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2017

Journal Article

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta

Zamir, Lyad, Singh, Reena, Nathan, Elisha, Patrick, Ralph, Yifa, Oren, Yahalom-Ronen, Yfat, Arrafi, Alaa A., Schultheiss, Thomas M., Suo, Shengbao, Han, Jing-Dong Jackie, Peng, Guangdun, Jing, Naihe, Wang, Yuliang, Palpant, Nathan, Tam, Patrick P. L., Harveyz, Richard P. and Tzahor, Eldad (2017). Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta. ELife, 6 e20994. doi: 10.7554/eLife.20994

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta

2017

Journal Article

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

Palpant, Nathan J., Pabon, Lil, Friedman, Clayton E., Roberts, Meredith, Hadland, Brandon, Zaunbrecher, Rebecca J., Bernstein, Irwin, Zheng, Ying and Murry, Charles E. (2017). Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells. Nature Protocols, 12 (1), 15-31. doi: 10.1038/nprot.2016.153

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

2016

Journal Article

Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5

Szabo, Linda, Morey, Robert, Palpant, Nathan J., Wang, Peter L., Afari, Nastaran, Jiang, Chuan, Parast, Mana M., Murry, Charles E., Laurent, Louise C. and Salzman, Julia (2016). Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5. Genome Biology, 17 (1) 263. doi: 10.1186/s13059-016-1123-9

Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5

2016

Journal Article

The developmental origins and lineage contributions of endocardial endothelium

Nakano, Atsushi, Nakano, Haruko, Smith, Kelly A. and Palpant, Nathan J. (2016). The developmental origins and lineage contributions of endocardial endothelium. Biochimica et Biophysica Acta. Molecular Cell Research, 1863 (7), 1937-1947. doi: 10.1016/j.bbamcr.2016.01.022

The developmental origins and lineage contributions of endocardial endothelium

2015

Journal Article

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

Szabo, Linda, Morey, Robert, Palpant, Nathan J., Wang, Peter L., Afari, Nastaran, Jiang, Chuan, Parast, Mana M., Murry, Charles E., Laurent, Louise C. and Salzman, Julia (2015). Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development. Genome Biology, 16 (1) 126. doi: 10.1186/s13059-015-0690-5

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

2015

Journal Article

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

Palpant, Nathan J., Hofsteen, Peter, Pabon, Lil, Reinecke, Hans and Murry, Charles E. (2015). Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes. PLoS ONE, 10 (5) 0126259, e0126259.1-e0126259. 19. doi: 10.1371/journal.pone.0126259

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

2015

Journal Article

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

Palpant, Nathan J., Pabon, Lil, Roberts, Meredith, Hadland, Brandon, Jones, Daniel, Jones, Christina, Moon, Randall T., Ruzzo, Walter L., Bernstein, Irwin, Zheng, Ying and Murry, Charles E. (2015). Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes. Development (Cambridge), 142 (18), 3198-3209. doi: 10.1242/dev.117010

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

2014

Journal Article

Proliferation at the heart of preadolescence

Palpant, Nathan J. and Murry, Charles E. (2014). Proliferation at the heart of preadolescence. Cell, 157 (4), 765-767. doi: 10.1016/j.cell.2014.04.025

Proliferation at the heart of preadolescence

2014

Journal Article

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

Chong, James J. H., Yang, Xiulan, Don, Creighton W., Minami, Elina, Liu, Yen-Wen, Weyers, Jill J., Mahoney, William M., Van Biber, Benjamin, Cook, Savannah M., Palpant, Nathan J., Gantz, Jay A., Fugate, James A., Muskheli, Veronica, Gough, G. Michael, Vogel, Keith W., Astley, Cliff A., Hotchkiss, Charlotte E., Baldessari, Audrey, Pabon, Lil, Reinecke, Hans, Gill, Edward A., Nelson, Veronica, Kiem, Hans-Peter, Laflamme, Michael A. and Murry, Charles E. (2014). Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature, 510 (7504), 273-277. doi: 10.1038/nature13233

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

2013

Journal Article

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

Palpant, Nathan J., Pabon, Lil, Rabinowitz, Jeremy S., Hadland, Brandon K., Stoick-Cooper, Cristi L., Paige, Sharon L., Bernstein, Irwin D., Moon, Randall T. and Murry, Charles E. (2013). Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development. Development (Cambridge), 140 (18), 3799-3808. doi: 10.1242/dev.094789

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

2013

Journal Article

Cardiopoietry in motion

Murry, Charles E., Palpant, Nathan J. and MacLellan, W. Robb (2013). Cardiopoietry in motion. Journal of the American College of Cardiology, 61 (23), 2339-2340. doi: 10.1016/j.jacc.2013.03.028

Cardiopoietry in motion

2013

Journal Article

Zinc finger nucleases: looking toward translation

Palpant, N. J. and Dudzinski, D. (2013). Zinc finger nucleases: looking toward translation. Gene Therapy, 20 (2), 121-127. doi: 10.1038/gt.2012.2

Zinc finger nucleases: looking toward translation

2012

Journal Article

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

Gantz, Jan A., Palpant, Nathan J., Welikson, Robert E., Hauschka, Stephen D., Murry, Charles E. and Laflamme, Michael A. (2012). Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells. PLoS ONE, 7 (10) e46971, 1-9. doi: 10.1371/journal.pone.0046971

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

2012

Journal Article

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

Shiba, Yuji, Fernandes, Sarah, Zhu, Wei-Zhong, Filice, Dominic, Muskheli, Veronica, Kim, Jonathan, Palpant, Nathan J., Gantz, Jay, Moyes, Kara W., Reinecke, Hans, Van Biber, Benjamin, Dardas, Todd, Mignone, John L., Izawa, Atsushi, Hanna, Ramy, Viswanathan, Mohan, Gold, Joseph D., Kotlikoff, Michael I., Sarvazyan, Narine, Kay, Matthew W., Murry, Charles E. and Laflamme, Michael A. (2012). Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature, 489 (7415), 322-325. doi: 10.1038/nature11317

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

2012

Journal Article

Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy

Davis, J., Yasuda, S., Palpant, N.J., Martindale, J., Stevenson, T., Converso, K. and Metzger, J.M. (2012). Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy. Journal of Molecular and Cellular Cardiology, 53 (3), 446-457. doi: 10.1016/j.yjmcc.2012.05.018

Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy

2012

Journal Article

Regenerative medicine: reprogramming the injured heart

Palpant, Nathan J. and Murry, Charles E. (2012). Regenerative medicine: reprogramming the injured heart. Nature, 485 (7400), 585-586. doi: 10.1038/485585a

Regenerative medicine: reprogramming the injured heart

2012

Journal Article

pH-responsive titratable inotropic performance of histidine-modified cardiac troponin i

Palpant, Nathan J., Houang, Evelyne M., Sham, Yuk Y. and Metzger, Joseph M. (2012). pH-responsive titratable inotropic performance of histidine-modified cardiac troponin i. Biophysical Journal, 102 (7), 1570-1579. doi: 10.1016/j.bpj.2012.01.024

pH-responsive titratable inotropic performance of histidine-modified cardiac troponin i

2011

Journal Article

Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies

Palpant, Nathan J., Bedada, Fikru B., Peacock, Brandon, Blazar, Bruce R., Metzger, Joseph M. and Tolar, Jakub (2011). Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies. American Journal of Physiology - Heart and Circulatory Physiology, 300 (1), H356-H365. doi: 10.1152/ajpheart.00774.2010

Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies

2010

Journal Article

Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains

Barnabei, Matthew S., Palpant, Nathan J. and Metzger, Joseph M. (2010). Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains. Physiological Genomics, 42A (2), 103-113. doi: 10.1152/physiolgenomics.00071.2010

Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains

2010

Journal Article

Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations

Palpant N.J., Houang E.M., Delport W., Hastings K.E.M., Onufriev A.V., Sham Y.Y. and Metzger J.M. (2010). Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations. Physiological Genomics, 42 (2), 287-299. doi: 10.1152/physiolgenomics.00033.2010

Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations