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2015

Journal Article

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

Palpant, Nathan J., Hofsteen, Peter, Pabon, Lil, Reinecke, Hans and Murry, Charles E. (2015). Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes. PLoS ONE, 10 (5) 0126259, e0126259.1-e0126259. 19. doi: 10.1371/journal.pone.0126259

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

2015

Journal Article

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

Palpant, Nathan J., Pabon, Lil, Roberts, Meredith, Hadland, Brandon, Jones, Daniel, Jones, Christina, Moon, Randall T., Ruzzo, Walter L., Bernstein, Irwin, Zheng, Ying and Murry, Charles E. (2015). Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes. Development (Cambridge), 142 (18), 3198-3209. doi: 10.1242/dev.117010

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

2014

Journal Article

Proliferation at the heart of preadolescence

Palpant, Nathan J. and Murry, Charles E. (2014). Proliferation at the heart of preadolescence. Cell, 157 (4), 765-767. doi: 10.1016/j.cell.2014.04.025

Proliferation at the heart of preadolescence

2014

Journal Article

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

Chong, James J. H., Yang, Xiulan, Don, Creighton W., Minami, Elina, Liu, Yen-Wen, Weyers, Jill J., Mahoney, William M., Van Biber, Benjamin, Cook, Savannah M., Palpant, Nathan J., Gantz, Jay A., Fugate, James A., Muskheli, Veronica, Gough, G. Michael, Vogel, Keith W., Astley, Cliff A., Hotchkiss, Charlotte E., Baldessari, Audrey, Pabon, Lil, Reinecke, Hans, Gill, Edward A., Nelson, Veronica, Kiem, Hans-Peter, Laflamme, Michael A. and Murry, Charles E. (2014). Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature, 510 (7504), 273-277. doi: 10.1038/nature13233

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

2013

Journal Article

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

Palpant, Nathan J., Pabon, Lil, Rabinowitz, Jeremy S., Hadland, Brandon K., Stoick-Cooper, Cristi L., Paige, Sharon L., Bernstein, Irwin D., Moon, Randall T. and Murry, Charles E. (2013). Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development. Development (Cambridge), 140 (18), 3799-3808. doi: 10.1242/dev.094789

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

2013

Journal Article

Cardiopoietry in motion

Murry, Charles E., Palpant, Nathan J. and MacLellan, W. Robb (2013). Cardiopoietry in motion. Journal of the American College of Cardiology, 61 (23), 2339-2340. doi: 10.1016/j.jacc.2013.03.028

Cardiopoietry in motion

2013

Journal Article

Zinc finger nucleases: looking toward translation

Palpant, N. J. and Dudzinski, D. (2013). Zinc finger nucleases: looking toward translation. Gene Therapy, 20 (2), 121-127. doi: 10.1038/gt.2012.2

Zinc finger nucleases: looking toward translation

2012

Journal Article

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

Gantz, Jan A., Palpant, Nathan J., Welikson, Robert E., Hauschka, Stephen D., Murry, Charles E. and Laflamme, Michael A. (2012). Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells. PLoS ONE, 7 (10) e46971, 1-9. doi: 10.1371/journal.pone.0046971

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

2012

Journal Article

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

Shiba, Yuji, Fernandes, Sarah, Zhu, Wei-Zhong, Filice, Dominic, Muskheli, Veronica, Kim, Jonathan, Palpant, Nathan J., Gantz, Jay, Moyes, Kara W., Reinecke, Hans, Van Biber, Benjamin, Dardas, Todd, Mignone, John L., Izawa, Atsushi, Hanna, Ramy, Viswanathan, Mohan, Gold, Joseph D., Kotlikoff, Michael I., Sarvazyan, Narine, Kay, Matthew W., Murry, Charles E. and Laflamme, Michael A. (2012). Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature, 489 (7415), 322-325. doi: 10.1038/nature11317

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

2012

Journal Article

Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy

Davis, J., Yasuda, S., Palpant, N.J., Martindale, J., Stevenson, T., Converso, K. and Metzger, J.M. (2012). Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy. Journal of Molecular and Cellular Cardiology, 53 (3), 446-457. doi: 10.1016/j.yjmcc.2012.05.018

Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy

2012

Journal Article

Regenerative medicine: reprogramming the injured heart

Palpant, Nathan J. and Murry, Charles E. (2012). Regenerative medicine: reprogramming the injured heart. Nature, 485 (7400), 585-586. doi: 10.1038/485585a

Regenerative medicine: reprogramming the injured heart

2012

Journal Article

pH-responsive titratable inotropic performance of histidine-modified cardiac troponin i

Palpant, Nathan J., Houang, Evelyne M., Sham, Yuk Y. and Metzger, Joseph M. (2012). pH-responsive titratable inotropic performance of histidine-modified cardiac troponin i. Biophysical Journal, 102 (7), 1570-1579. doi: 10.1016/j.bpj.2012.01.024

pH-responsive titratable inotropic performance of histidine-modified cardiac troponin i

2011

Journal Article

Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies

Palpant, Nathan J., Bedada, Fikru B., Peacock, Brandon, Blazar, Bruce R., Metzger, Joseph M. and Tolar, Jakub (2011). Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies. American Journal of Physiology - Heart and Circulatory Physiology, 300 (1), H356-H365. doi: 10.1152/ajpheart.00774.2010

Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies

2010

Journal Article

Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains

Barnabei, Matthew S., Palpant, Nathan J. and Metzger, Joseph M. (2010). Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains. Physiological Genomics, 42A (2), 103-113. doi: 10.1152/physiolgenomics.00071.2010

Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains

2010

Journal Article

Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations

Palpant N.J., Houang E.M., Delport W., Hastings K.E.M., Onufriev A.V., Sham Y.Y. and Metzger J.M. (2010). Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations. Physiological Genomics, 42 (2), 287-299. doi: 10.1152/physiolgenomics.00033.2010

Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations

2010

Journal Article

Aesthetic cardiology: adipose-derived stem cells for myocardial repair

Palpant, N.J. and Metzger, J.M. (2010). Aesthetic cardiology: adipose-derived stem cells for myocardial repair. Current Stem Cell Research and Therapy, 5 (2), 145-152. doi: 10.2174/157488810791268654

Aesthetic cardiology: adipose-derived stem cells for myocardial repair

2009

Journal Article

Artificial selection for whole animal low intrinsic aerobic capacity co-segregates with hypoxia-induced cardiac pump failure

Palpant, Nathan J., Szatkowski, Michael L., Wang, Wang, Townsend, DeWayne, Bedada, Fikru B., Koch, Lauren G., Britton, Steven L. and Metzger, Joseph M. (2009). Artificial selection for whole animal low intrinsic aerobic capacity co-segregates with hypoxia-induced cardiac pump failure. PLoS One, 4 (7) e6117, e6117. doi: 10.1371/journal.pone.0006117

Artificial selection for whole animal low intrinsic aerobic capacity co-segregates with hypoxia-induced cardiac pump failure

2009

Journal Article

Single histidine button in cardiac troponin I sustains heart performance in response to severe hypercapnic respiratory acidosis in vivo

Palpant, Nathan J., D'Alecy, Louis G. and Metzger, Joseph M. (2009). Single histidine button in cardiac troponin I sustains heart performance in response to severe hypercapnic respiratory acidosis in vivo. FASEB Journal, 23 (5), 1529-1540. doi: 10.1096/fj.08-121996

Single histidine button in cardiac troponin I sustains heart performance in response to severe hypercapnic respiratory acidosis in vivo

2008

Journal Article

Molecular Cardiology in Translation: Gene, Cell and Chemical-Based Experimental Therapeutics for the Failing Heart

Turner, Immanuel, Belema-Bedada, Fikru, Martindale, Joshua, Townsend, DeWayne, Wang, Wang, Palpant, Nathan, Yasuda, So-chiro, Barnabei, Matthew, Fomicheva, Ekaterina and Metzger, Joseph M. (2008). Molecular Cardiology in Translation: Gene, Cell and Chemical-Based Experimental Therapeutics for the Failing Heart. Journal of Cardiovascular Translational Research, 1 (4), 317-327. doi: 10.1007/s12265-008-9065-6

Molecular Cardiology in Translation: Gene, Cell and Chemical-Based Experimental Therapeutics for the Failing Heart

2008

Journal Article

Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction

Palpant, Nathan J., Day, Sharlene M., Herron, Todd J., Converso, Kimber L. and Metzger, Joseph M. (2008). Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction. Cardiovascular Research, 80 (2), 209-218. doi: 10.1093/cvr/cvn198

Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction