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2026

Journal Article

Computational modelling of cell identity

Shim, Woo Jun, Chow, Chris Siu Yeung, Bao, Shaine Chenxin, Zhao, Qiongyi and Palpant, Nathan J. (2026). Computational modelling of cell identity. Biochemical Journal, 483 (6), 1049-1071. doi: 10.1042/bcj20250132

Computational modelling of cell identity

2026

Journal Article

Identifying therapeutic targets in low‐grade serous ovarian carcinomas with no specific molecular profile

Pishas, Kathleen I, Cowley, Karla J, Marinovic, Evanny, Köbel, Martin, Llaurado‐Fernandez, Marta, Kim, Hannah, Bao, Shaine Chenxin, Mizikovsky, Dalia, Palpant, Nathan J, Shrestha, Raunak, Vary, Robert, Luu, Jennii, Meunier, Liliane, Semple, Timothy, Blancafort, Pilar, Golden, Emily, Cohen, Paul A, Carey, Mark S, Campbell, Ian G, Simpson, Kaylene J and Cheasley, Dane (2026). Identifying therapeutic targets in low‐grade serous ovarian carcinomas with no specific molecular profile. The Journal of Pathology path.70075. doi: 10.1002/path.70075

Identifying therapeutic targets in low‐grade serous ovarian carcinomas with no specific molecular profile

2026

Journal Article

Preparing healthcare providers to use polygenic risk scores: a qualitative study of learning needs and educational preferences

Clark, Amy, Wallingford, Courtney K., Berkman, Jennifer, McInerney-Leo, Aideen, Nisselle, Amy, Terrill, Bronwyn, Palpant, Nathan, Young, Mary-Anne, James, Paul A. and Yanes, Tatiane (2026). Preparing healthcare providers to use polygenic risk scores: a qualitative study of learning needs and educational preferences. BMJ Open, 16 (5) e111898, e111898-5. doi: 10.1136/bmjopen-2025-111898

Preparing healthcare providers to use polygenic risk scores: a qualitative study of learning needs and educational preferences

2026

Journal Article

A scalable, multi-resolution consensus clustering approach for prioritizing robust signals from high-throughput screens

Bao, Shaine Chenxin, Pishas, Kathleen I, Cowley, Karla J, Zhao, Qiongyi, Goodall, Emily C A, Henderson, Ian R, Liu, Xin, Marinovic, Evanny, Carey, Mark S, Campbell, Ian G, Simpson, Kaylene J, Cheasley, Dane, Mizikovsky, Dalia and Palpant, Nathan J (2026). A scalable, multi-resolution consensus clustering approach for prioritizing robust signals from high-throughput screens. Briefings in Bioinformatics, 27 (3) bbag242. doi: 10.1093/bib/bbag242

A scalable, multi-resolution consensus clustering approach for prioritizing robust signals from high-throughput screens

2026

Journal Article

Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes

Cao, Yuanzhao, Redd, Meredith A., Outhwaite, Jennifer E., Mizikovsky, Dalia, Shim, Woo Jun, Fang, Chen, Vedelago, Courtney, Tan, Clarissa, Wu, Zhixuan, Daygon, Dara, Stark, Terra, Palfreyman, Robin, Chiu, Han Sheng, Thomas, Ulrich, Dragicevic, Elena, Sng, Julian D. J., Saez, Natalie J., Barrett, Helen L., Dorey, Emily S., King, Glenn F., Wuethrich, Alain, Trau, Matt, Shah, Sonia, Short, Kirsty R. and Palpant, Nathan J. (2026). Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes. Nature Communications. doi: 10.1038/s41467-026-71809-x

Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes

2026

Other Outputs

Protocol-dependent cardiomyocyte states determine disease modelling capacity of human iPSCs

Shen, Sophie, Tan, Clarissa, Cao, Yuanzhao, Chow, Chris Siu Yeung, Mizikovsky, Dalia, Reid, Janice, Dingwall, Steve, Prowse, Andrew, Sun, Yuliangzi, Wu, Zhixuan, Negi, Sumedha, Bao, Shaine Chenxin, Sinniah, Enakshi, Shim, Woo Jun, Zhao, Qiongyi, Thorpe, Jordan, Zahabi, Azadeh, Hanna, Amy, Cheng, Trishia, Hill, Adam, Hudson, James, Chong, James J. H. and Palpant, Nathan J. (2026). Protocol-dependent cardiomyocyte states determine disease modelling capacity of human iPSCs. doi: 10.64898/2026.03.29.715135

Protocol-dependent cardiomyocyte states determine disease modelling capacity of human iPSCs

2026

Other Outputs

Hierarchical control of cardiomyocyte maturation and ischaemia sensitivity by metabolic culture conditions

Cao, Yuanzhao, Chow, Chris Siu Yeung, Negi, Sumedha, Shim, Woo Jun, Shen, Sophie, Fang, Chen and Palpant, Nathan J. (2026). Hierarchical control of cardiomyocyte maturation and ischaemia sensitivity by metabolic culture conditions. doi: 10.64898/2026.03.12.711459

Hierarchical control of cardiomyocyte maturation and ischaemia sensitivity by metabolic culture conditions

2026

Journal Article

Bacterial reporter–paired scRNA sequencing reveals cross talk between zinc starvation and zinc toxicity in macrophage antibacterial defense

von Pein, Jessica B., Andersen, Stacey B., Xu, Jon, Phan, Minh-Duy, Dalton, Emma K., Koczerka, Michael, Stocks, Claudia J., Curson, James E. B., Vandeleur, Zoe, Condon, Nicholas D., Hancock, Steven J., Nefzger, Christian M., Palpant, Nathan J., Ramnath, Divya, Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2026). Bacterial reporter–paired scRNA sequencing reveals cross talk between zinc starvation and zinc toxicity in macrophage antibacterial defense. Proceedings of the National Academy of Sciences, 123 (11) e2530503123, 1-12. doi: 10.1073/pnas.2530503123

Bacterial reporter–paired scRNA sequencing reveals cross talk between zinc starvation and zinc toxicity in macrophage antibacterial defense

2026

Journal Article

Hi1a delivered in various modes reduces myocardial infarct size in mice

Wu, Jianxin, Gao, Ling, Villanueva, Jeanette, Doyle, Aoife, Dutta, Sanjay, Joshi, Yashutosh, MacLean, Campbell, Kesteven, Scott, King, Glenn, Palpant, Nathan, Feneley, Michael, Iismaa, Siiri, Graham, Robert and Macdonald, Peter (2026). Hi1a delivered in various modes reduces myocardial infarct size in mice. Journal of Molecular and Cellular Cardiology Plus, 15 100753, 100753. doi: 10.1016/j.jmccpl.2025.100753

Hi1a delivered in various modes reduces myocardial infarct size in mice

2026

Journal Article

Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial Infarction

Hume, Robert, Warwick, Jessica, Shim, Woo Jun, Malecki, Cassandra, Li, Mengbo, Harney, Dylan, Slaughter, Eugene, Wang, XiaoSuo, Nguyen, Lisa, Cole, Louise, Edelman, James, Rashid, Fairooj, Houlahan, Callum, Gao, Antony, Ferguson, Angela, Chong, James, Larance, Mark, O'Sullivan, John, Palpant, Nathan, Bannon, Paul and Lal, Sean (2026). Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial Infarction. Journal of Molecular and Cellular Cardiology Plus, 15 100505, 100505. doi: 10.1016/j.jmccpl.2025.100505

Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial Infarction

2026

Journal Article

The changing landscape of gene expression analysis

Zhao, Qiongyi, Shen, Sophie, Shim, Woo Jun and Palpant, Nathan J. (2026). The changing landscape of gene expression analysis. Briefings in Bioinformatics, 27 (2) bbag185, 2. doi: 10.1093/bib/bbag185

The changing landscape of gene expression analysis

2026

Journal Article

Nanopatterned cell sheet assembly of biomimetic cardiac laminae for modeling structure-function relationships

Jiao, Alex, Macadangdang, Jesse, Kim, Jinsung, Moerk, Charles Travis, Palpant, Nathan J., Mengsteab, Paulos Y., Park, Hyeon-Cheol, Murry, Charles E. and Kim, Deok-Ho (2026). Nanopatterned cell sheet assembly of biomimetic cardiac laminae for modeling structure-function relationships. Biomaterials Research, 30 0339, 1-12. doi: 10.34133/bmr.0339

Nanopatterned cell sheet assembly of biomimetic cardiac laminae for modeling structure-function relationships

2025

Journal Article

Conserved facultative heterochromatin across cell types identify regulatory sequences underpinning cell identity and disease

Sinniah, Enakshi, Mizikovsky, Dalia, Shim, Woo Jun, Chow, Chris Siu Yeung, Souilmi, Yassine, Cheng, Fei-Fei, Zeng, Zhili, Laurie, Jordan, Foster, Matthew, Shah, Sonia, Bodén, Mikael, Zeng, Jian, Llamas, Bastien and Palpant, Nathan J. (2025). Conserved facultative heterochromatin across cell types identify regulatory sequences underpinning cell identity and disease. Nucleic Acids Research, 53 (20) gkaf971, 1-23. doi: 10.1093/nar/gkaf971

Conserved facultative heterochromatin across cell types identify regulatory sequences underpinning cell identity and disease

2025

Journal Article

Epigenomics and transcriptomics profiles of developing zebrafish heart cells

Chahal, Gulrez, Eichenlaub, Michael P., Tondl, Markus, Pawlak, Michał, Mohenska, Monika, Grimm, Lin, Bottrell, Lauren, Drvodelic, Mark, Alaei, Sara, Hallab, Jeannette, Waylen, Lisa N., Polo, Jose M., Blanpain, Cédric, Palpant, Nathan, Rossello, Fernando J., Änkö, Minna-Liisa, Currie, Peter D., Hogan, Benjamin M., Winata, Cecilia, Salimova, Ekaterina, Nim, Hieu T. and Ramialison, Mirana (2025). Epigenomics and transcriptomics profiles of developing zebrafish heart cells. Scientific Data, 12 (1) 1620, 1-10. doi: 10.1038/s41597-025-05895-9

Epigenomics and transcriptomics profiles of developing zebrafish heart cells

2025

Other Outputs

Contractile function maintains cardiomyocyte differentiation and inhibits cell cycle activity

Devilée, Lynn A.C., Reid, Janice D., Krycer, James R., Robinson, Harley R., Humphrey, Sean J., Chow, Chris Siu Yeung, Lor, Mary, Fitzsimmons, Rebecca L., Wang, Qing-Dong, Doran, Michael, Porrello, Enzo R., Palpant, Nathan J., Foster, Simon R., Mills, Richard J. and Hudson, James E. (2025). Contractile function maintains cardiomyocyte differentiation and inhibits cell cycle activity. doi: 10.1101/2025.08.19.671044

Contractile function maintains cardiomyocyte differentiation and inhibits cell cycle activity

2025

Conference Publication

Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes

Cao, Y., Redd, M., Outhwaite, J., Mizikovsky, D., Shim, W., Fang, C., Wu, Z., Daygon, D., Stark, T., Palfreyman, R., Chiu, H., Tan, C., Thomas, U., Dragicevic, E., Sng, J., Barrett, H., Dorey, E., Shah, S., Short, K. and Palpant, N. (2025). Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes. 73rd Annual Scientific Meeting ofthe Cardiac Society of Australia and New Zealand, Brisbane, QLD Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier Australia. doi: 10.1016/j.hlc.2025.06.821

Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes

2025

Conference Publication

Recovery of rat hearts after cold storage with acid sensing ion channel inhibitor Hi1a varies by sex

Dutta, S. D., Villanueva, J., Gao, L., Doyle, A., Palpant, N., King, G. and Macdonald, P. (2025). Recovery of rat hearts after cold storage with acid sensing ion channel inhibitor Hi1a varies by sex. World Transplant Congress (WTC), San Francisco, CA United States, 2-6 August 2025. New York, NY United States: Elsevier.

Recovery of rat hearts after cold storage with acid sensing ion channel inhibitor Hi1a varies by sex

2025

Conference Publication

Multidimensional-Spatial Profiling of Human Heart Failure Reveals New Cardiomyocyte Subtypes and Fibro-Inflammatory Niches

Rashid, F., Muthiah, K., Qin, A., Sun, V., Nim, H., Sivasubramaniam, V., Barua, S., Eckford, H., O’Neil, T., Patrick, E., Clayton, Z., Reyes, L., Palpant, N., Ramialison, M., Hayward, C., Kizana, E. and Chong, J. (2025). Multidimensional-Spatial Profiling of Human Heart Failure Reveals New Cardiomyocyte Subtypes and Fibro-Inflammatory Niches. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Sydney, NSW Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.018

Multidimensional-Spatial Profiling of Human Heart Failure Reveals New Cardiomyocyte Subtypes and Fibro-Inflammatory Niches

2025

Conference Publication

Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial Infarction

Hume, R., Warwick, J., Shim, W., Malecki, C., Li, M., Harney, D., Slaughter, E., Wang, X., Nguyen, L., Cole, L., Edelman, J., Rashid, F., Houlahan, C., Gao, A., Ferguson, A., Chong, J., Larance, M., O’Sullivan, J., Palpant, N., Bannon, P. and Lal, S. (2025). Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial Infarction. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Sydney, NSW Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.332

Human Hearts Intrinsically Increase Cardiomyocyte Mitosis Following Myocardial Infarction

2025

Journal Article

A pluripotent stem cell atlas of multilineage differentiation

Shen, Sophie, Werner, Tessa, Chiu, Han Sheng, Chen, Xiaoli, Nguyen, Quan and Palpant, Nathan J. (2025). A pluripotent stem cell atlas of multilineage differentiation. Scientific Data, 12 (1) 1238, 1238. doi: 10.1038/s41597-025-05549-w

A pluripotent stem cell atlas of multilineage differentiation