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2017

Conference Publication

Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium

Palpant, Nathan, Wang, Yuliang, Hadland, Brandon, Zaunbrecher, Rebecca, Redd, Meredith, Pabon, Lil, Jain, Rajan, Epstein, Jonathan, Zheng, Ying, Bernstein, Irwin, Margolin, Adam and Murry, Charles (2017). Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium. 18th International Congress of Developmental Biology, Singapore, Singapore, 18 - 22 June 2017. E Park, Shannon, Clare Ireland: Elsevier Ireland. doi: 10.1016/j.mod.2017.04.263

Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium

2017

Journal Article

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

Palpant, Nathan J., Pabon, Lil, Friedman, Clayton E., Roberts, Meredith, Hadland, Brandon, Zaunbrecher, Rebecca J., Bernstein, Irwin, Zheng, Ying and Murry, Charles E. (2017). Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells. Nature Protocols, 12 (1), 15-31. doi: 10.1038/nprot.2016.153

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

2016

Journal Article

Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5

Szabo, Linda, Morey, Robert, Palpant, Nathan J., Wang, Peter L., Afari, Nastaran, Jiang, Chuan, Parast, Mana M., Murry, Charles E., Laurent, Louise C. and Salzman, Julia (2016). Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5. Genome Biology, 17 (1) 263. doi: 10.1186/s13059-016-1123-9

Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5

2016

Journal Article

The developmental origins and lineage contributions of endocardial endothelium

Nakano, Atsushi, Nakano, Haruko, Smith, Kelly A. and Palpant, Nathan J. (2016). The developmental origins and lineage contributions of endocardial endothelium. Biochimica et Biophysica Acta. Molecular Cell Research, 1863 (7), 1937-1947. doi: 10.1016/j.bbamcr.2016.01.022

The developmental origins and lineage contributions of endocardial endothelium

2015

Journal Article

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

Szabo, Linda, Morey, Robert, Palpant, Nathan J., Wang, Peter L., Afari, Nastaran, Jiang, Chuan, Parast, Mana M., Murry, Charles E., Laurent, Louise C. and Salzman, Julia (2015). Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development. Genome Biology, 16 (1) 126. doi: 10.1186/s13059-015-0690-5

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

2015

Journal Article

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

Palpant, Nathan J., Hofsteen, Peter, Pabon, Lil, Reinecke, Hans and Murry, Charles E. (2015). Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes. PLoS ONE, 10 (5) 0126259, e0126259.1-e0126259. 19. doi: 10.1371/journal.pone.0126259

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

2015

Conference Publication

Elevated microjet gradient device for directing spatiotemporal differentiation of embryonic stem cells

Bhattacharjee, N., Palpant, N. J., Murry, C. E. and Folch, A. (2015). Elevated microjet gradient device for directing spatiotemporal differentiation of embryonic stem cells. MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2015, Gyeongju, South Korea, 25-29 October 2015. San Diego, CA United States: Chemical and Biological Microsystems Society.

Elevated microjet gradient device for directing spatiotemporal differentiation of embryonic stem cells

2015

Journal Article

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

Palpant, Nathan J., Pabon, Lil, Roberts, Meredith, Hadland, Brandon, Jones, Daniel, Jones, Christina, Moon, Randall T., Ruzzo, Walter L., Bernstein, Irwin, Zheng, Ying and Murry, Charles E. (2015). Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes. Development (Cambridge), 142 (18), 3198-3209. doi: 10.1242/dev.117010

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

2014

Journal Article

Proliferation at the heart of preadolescence

Palpant, Nathan J. and Murry, Charles E. (2014). Proliferation at the heart of preadolescence. Cell, 157 (4), 765-767. doi: 10.1016/j.cell.2014.04.025

Proliferation at the heart of preadolescence

2014

Journal Article

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

Chong, James J. H., Yang, Xiulan, Don, Creighton W., Minami, Elina, Liu, Yen-Wen, Weyers, Jill J., Mahoney, William M., Van Biber, Benjamin, Cook, Savannah M., Palpant, Nathan J., Gantz, Jay A., Fugate, James A., Muskheli, Veronica, Gough, G. Michael, Vogel, Keith W., Astley, Cliff A., Hotchkiss, Charlotte E., Baldessari, Audrey, Pabon, Lil, Reinecke, Hans, Gill, Edward A., Nelson, Veronica, Kiem, Hans-Peter, Laflamme, Michael A. and Murry, Charles E. (2014). Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature, 510 (7504), 273-277. doi: 10.1038/nature13233

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

2014

Book Chapter

Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts

Zhu, Wei-Zhong, Filice, Dominic, Palpant, Nathan J. and Laflamme, Michael A. (2014). Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts. Cardiac tissue engineering: methods and protocols. (pp. 229-247) edited by Radisci, Milica and Black III, Lauren D.. New York, NY United States: Springer New York. doi: 10.1007/978-1-4939-1047-2_20

Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts

2013

Journal Article

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

Palpant, Nathan J., Pabon, Lil, Rabinowitz, Jeremy S., Hadland, Brandon K., Stoick-Cooper, Cristi L., Paige, Sharon L., Bernstein, Irwin D., Moon, Randall T. and Murry, Charles E. (2013). Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development. Development (Cambridge), 140 (18), 3799-3808. doi: 10.1242/dev.094789

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

2013

Journal Article

Cardiopoietry in motion

Murry, Charles E., Palpant, Nathan J. and MacLellan, W. Robb (2013). Cardiopoietry in motion. Journal of the American College of Cardiology, 61 (23), 2339-2340. doi: 10.1016/j.jacc.2013.03.028

Cardiopoietry in motion

2013

Book Chapter

Human dignity and the debate over early human embryos

Palpant, Nathan J. and Holland, Suzanne (2013). Human dignity and the debate over early human embryos. Human dignity in bioethics: from worldviews to the public square. (pp. 239-263) New York, NY, United States: Routledge. doi: 10.4324/9780203075005

Human dignity and the debate over early human embryos

2013

Journal Article

Zinc finger nucleases: looking toward translation

Palpant, N. J. and Dudzinski, D. (2013). Zinc finger nucleases: looking toward translation. Gene Therapy, 20 (2), 121-127. doi: 10.1038/gt.2012.2

Zinc finger nucleases: looking toward translation

2013

Book Chapter

Human dignity in the throes?: An introduction to the volume

Dilley, Stephen and Palpant, Nathan J. (2013). Human dignity in the throes?: An introduction to the volume. Human Dignity in Bioethics: From Worldviews to the Public Square. (pp. 3-18) New York, NY United States: Taylor and Francis. doi: 10.4324/9780203075005

Human dignity in the throes?: An introduction to the volume

2013

Book

Human dignity in bioethics: From worldviews to the public square

Dilley, Stephen and Palpant, Nathan J. (2013). Human dignity in bioethics: From worldviews to the public square. New York, United States: Routledge. doi: 10.4324/9780203075005

Human dignity in bioethics: From worldviews to the public square

2012

Journal Article

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

Gantz, Jan A., Palpant, Nathan J., Welikson, Robert E., Hauschka, Stephen D., Murry, Charles E. and Laflamme, Michael A. (2012). Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells. PLoS ONE, 7 (10) e46971, 1-9. doi: 10.1371/journal.pone.0046971

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

2012

Journal Article

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

Shiba, Yuji, Fernandes, Sarah, Zhu, Wei-Zhong, Filice, Dominic, Muskheli, Veronica, Kim, Jonathan, Palpant, Nathan J., Gantz, Jay, Moyes, Kara W., Reinecke, Hans, Van Biber, Benjamin, Dardas, Todd, Mignone, John L., Izawa, Atsushi, Hanna, Ramy, Viswanathan, Mohan, Gold, Joseph D., Kotlikoff, Michael I., Sarvazyan, Narine, Kay, Matthew W., Murry, Charles E. and Laflamme, Michael A. (2012). Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature, 489 (7415), 322-325. doi: 10.1038/nature11317

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

2012

Journal Article

Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy

Davis, J., Yasuda, S., Palpant, N.J., Martindale, J., Stevenson, T., Converso, K. and Metzger, J.M. (2012). Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy. Journal of Molecular and Cellular Cardiology, 53 (3), 446-457. doi: 10.1016/j.yjmcc.2012.05.018

Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy