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2022

Other Outputs

Methods and compositions for multiplexing cell analysis

Palpant, Nathan, Anderson, Stacey, Werner, Tessa, Lukowski, Samuel and Shen, Sophie (2022). Methods and compositions for multiplexing cell analysis. PCT/AU2022/051476.

Methods and compositions for multiplexing cell analysis

2022

Journal Article

The ins and outs of cellular pH during cardiac ischemia

Cao, Yuanzhao and Palpant, Nathan J. (2022). The ins and outs of cellular pH during cardiac ischemia. Journal of Molecular and Cellular Cardiology, 174, 133-134. doi: 10.1016/j.yjmcc.2022.12.004

The ins and outs of cellular pH during cardiac ischemia

2022

Journal Article

Defining the Fetal Gene Program at Single-Cell Resolution in Pediatric Dilated Cardiomyopathy

Mehdiabadi, Neda R., Boon Sim, Choon, Phipson, Belinda, Kalathur, Ravi K.R., Sun, Yuliangzi, Vivien, Celine J., ter Huurne, Menno, Piers, Adam T., Hudson, James E., Oshlack, Alicia, Weintraub, Robert G., Konstantinov, Igor E., Palpant, Nathan J., Elliott, David A. and Porrello, Enzo R. (2022). Defining the Fetal Gene Program at Single-Cell Resolution in Pediatric Dilated Cardiomyopathy. Circulation, 146 (14), 1105-1108. doi: 10.1161/circulationaha.121.057763

Defining the Fetal Gene Program at Single-Cell Resolution in Pediatric Dilated Cardiomyopathy

2022

Journal Article

Don’t turn off the tap! The importance of discovery science to the Australian cardiovascular sector and improving clinical outcomes into the future

Bursill, Christina A., Smith, Nicola J., Palpant, Nathan, Tan, Isabella, Sunde, Margaret, Harvey, Richard P., Lewis, Benjamin, Figtree, Gemma A., Vandenberg, Jamie I. and on behalf of the Australian Cardiovascular Alliance (2022). Don’t turn off the tap! The importance of discovery science to the Australian cardiovascular sector and improving clinical outcomes into the future. Heart, Lung and Circulation, 31 (10), 1321-1332. doi: 10.1016/j.hlc.2022.06.669

Don’t turn off the tap! The importance of discovery science to the Australian cardiovascular sector and improving clinical outcomes into the future

2022

Journal Article

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

Sinniah, Enakshi, Wu, Zhixuan, Shen, Sophie, Naval-Sanchez, Marina, Chen, Xiaoli, Lim, Junxian, Helfer, Abbigail, Iyer, Abishek, Tng, Jiahui, Lucke, Andrew J., Reid, Robert C., Redd, Meredith A., Nefzger, Christian M., Fairlie, David P. and Palpant, Nathan J. (2022). Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation. Cell Reports, 39 (7) 110818, 1-21. doi: 10.1016/j.celrep.2022.110818

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

2022

Conference Publication

Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, D., Clayton, Z., Prowse, A., Dingwall, S., George, J., Shah, H., Paterson, H., Jeyaprakesh, P., Wu, Z., Campbell, T., Kotake, Y., Turnbull, S., Nguyen, Q., Grieve, S., Palpant, N., Pathan, F., Kizana, E., Kumar, S., Gray, P. and Chong, J. (2022). Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. 70th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Gold Coast, QLD Australia, 11-14 August 2022. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2022.06.004

Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

2022

Book Chapter

Analysing genetic programs of cell differentiation to study cardiac cell diversification

Wu, Zhixuan, Shen, Sophie, Sun, Yuliangzi, Werner, Tessa, Bradford, Stephen T. and Palpant, Nathan J. (2022). Analysing genetic programs of cell differentiation to study cardiac cell diversification. Advanced technologies in cardiovascular bioengineering. (pp. 125-167) edited by Jianyi Zhang and Vahid Serpooshan. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-86140-7_8

Analysing genetic programs of cell differentiation to study cardiac cell diversification

Featured

2021

Journal Article

Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle

Lo, Harriet P., Lim, Ye-Wheen, Xiong, Zherui, Martel, Nick, Ferguson, Charles, Ariotti, Nicholas, Giacomotto, Jean, Rae, James, Floetenmeyer, Matthias, Moradi, Shayli Varasteh, Gao, Ya, Tillu, Vikas A., Xia, Di, Wang, Huang, Rahnama, Samira, Nixon, Susan J., Bastiani, Michele, Day, Ryan D., Smith, Kelly A., Palpant, Nathan J., Johnston, Wayne A., Alexandrov, Kirill, Collins, Brett M., Hall, Thomas E. and Parton, Robert G. (2021). Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle. Journal of Cell Biology, 220 (12) e201905065. doi: 10.1083/jcb.201905065

Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle

2021

Journal Article

Therapeutic Inhibition of Acid Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury (vol 144, pg 947, 2021)

Redd, Meredith A., Scheuer, Sarah E., Saez, Natalie J., Yoshikawa, Yusuke, Chiu, Han Sheng, Gao, Ling, Hicks, Mark, Villanueva, Jeanette E., Joshi, Yashutosh, Chow, Chun Yuen, Cuellar-Partida, Gabriel, Peart, Jason N., Hoe, Louise E. See, Chen, Xiaoli, Sun, Yuliangzi, Suen, Jacky Y., Hatch, Robert J., Rollo, Ben, Xia, Di, Alzubaidi, Mubarak A. H., Maljevic, Snezana, Quaife-Ryan, Gregory A., Hudson, James E., Porrello, Enzo R., White, Melanie Y., Cordwell, Stuart J., Fraser, John F., Petrou, Steven, Reichelt, Melissa E. ... Palpant, Nathan J. (2021). Therapeutic Inhibition of Acid Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury (vol 144, pg 947, 2021). Circulation, 144 (12), E211-E211. doi: 10.1161/CIR.0000000000001020

Therapeutic Inhibition of Acid Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury (vol 144, pg 947, 2021)

2021

Journal Article

scGPS: determining cell states and global fate potential of subpopulations

Thompson, Michael, Matsumoto, Maika, Ma, Tianqi, Senabouth, Anne, Palpant, Nathan J., Powell, Joseph E. and Nguyen, Quan (2021). scGPS: determining cell states and global fate potential of subpopulations. Frontiers in Genetics, 12 666771, 666771. doi: 10.3389/fgene.2021.666771

scGPS: determining cell states and global fate potential of subpopulations

2021

Journal Article

Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype

Kojic, Marija, Gawda, Tomasz, Gaik, Monika, Begg, Alexander, Salerno-Kochan, Anna, Kurniawan, Nyoman D., Jones, Alun, Drożdżyk, Katarzyna, Kościelniak, Anna, Chramiec-Głąbik, Andrzej, Hediyeh-Zadeh, Soroor, Kasherman, Maria, Shim, Woo Jun, Sinniah, Enakshi, Genovesi, Laura A., Abrahamsen, Rannvá K., Fenger, Christina D., Madsen, Camilla G., Cohen, Julie S., Fatemi, Ali, Stark, Zornitza, Lunke, Sebastian, Lee, Joy, Hansen, Jonas K., Boxill, Martin F., Keren, Boris, Marey, Isabelle, Saenz, Margarita S., Brown, Kathleen ... Wainwright, Brandon J. (2021). Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype. Nature Communications, 12 (1) 2678, 2678. doi: 10.1038/s41467-021-22888-5

Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype

2021

Journal Article

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

Neavin, Drew, Nguyen, Quan, Daniszewski, Maciej S., Liang, Helena H., Chiu, Han Sheng, Wee, Yong Kiat, Senabouth, Anne, Lukowski, Samuel W., Crombie, Duncan E., Lidgerwood, Grace E., Hernández, Damián, Vickers, James C., Cook, Anthony L., Palpant, Nathan J., Pébay, Alice, Hewitt, Alex W. and Powell, Joseph E. (2021). Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells. Genome Biology, 22 (1) 76, 1-19. doi: 10.1186/s13059-021-02293-3

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

2021

Book Chapter

scIVA: single cell database and tools for interactive visualisation and analysis

Crowhurst, Liam M., Mulay, Onkar, Palpant, Nathan and Nguyen, Quan H. (2021). scIVA: single cell database and tools for interactive visualisation and analysis. Practical guide to life science databases. (pp. 191-205) edited by Imad Abugessaisa and Takeya Kasukawa. Singapore: Springer. doi: 10.1007/978-981-16-5812-9_10

scIVA: single cell database and tools for interactive visualisation and analysis

2020

Other Outputs

Genome-edited induced pluripotent stem cells, and cells derived therefrom, and uses thereof

Palpant, Nathan and Redd, Meredith Ann (2020). Genome-edited induced pluripotent stem cells, and cells derived therefrom, and uses thereof. 17/116332.

Genome-edited induced pluripotent stem cells, and cells derived therefrom, and uses thereof

2020

Journal Article

Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep

Millar, Jonathan E., Bartnikowski, Nicole, Passmore, Margaret R., Obonyo, Nchafatso G, Malfertheiner, Maximillian V., von Bahr, Viktor, Redd, Meredith A., See Hoe, Louise, Ki, Katrina K., Pedersen, Sanne, Boyle, Andrew J., Baillie, J Kenneth, Shekar, Kiran, Palpant, Nathan, Suen, Jacky Y., Matthay, Michael A., McAuley, Daniel F., Fraser, John F. and Combining Extracorporeal Life Support and Cell Therapy in Critical Illness (CELTIC) investigators (2020). Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep. American Journal of Respiratory and Critical Care Medicine, 202 (3) rccm.201911-2143OC, 383-392. doi: 10.1164/rccm.201911-2143oc

Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep

2020

Conference Publication

A spider-venom peptide for preventing ischemic injuries of the heart: application to heart transplant and myocardial infarction

Redd, M. A., Scheuer, S. E., Saez, N. J., Macdonald, P. S., Palpant, N. J. and King, G. F. (2020). A spider-venom peptide for preventing ischemic injuries of the heart: application to heart transplant and myocardial infarction. Venom Week, Gainesville, FL, United States, 4-7 March, 2020. Oxford, United Kingdom : Elsevier.

A spider-venom peptide for preventing ischemic injuries of the heart: application to heart transplant and myocardial infarction

2020

Other Outputs

Human pluripotent stem cell derived endocardial endothelium

Murry, Charles E., Pabon, Lil and Palpant, Nathan (2020). Human pluripotent stem cell derived endocardial endothelium. 10612002 (2020).

Human pluripotent stem cell derived endocardial endothelium

2019

Journal Article

Genotype-free demultiplexing of pooled single-cell RNA-seq

Xu, Jun, Falconer, Caitlin, Nguyen, Quan, Crawford, Joanna, McKinnon, Brett D., Mortlock, Sally, Senabouth, Anne, Andersen, Stacey, Chiu, Han Sheng, Jiang, Longda, Palpant, Nathan J., Yang, Jian, Mueller, Michael D., Hewitt, Alex W., Pébay, Alice, Montgomery, Grant W., Powell, Joseph E. and Coin, Lachlan J. M. (2019). Genotype-free demultiplexing of pooled single-cell RNA-seq. Genome Biology, 20 (1) 290, 290. doi: 10.1186/s13059-019-1852-7

Genotype-free demultiplexing of pooled single-cell RNA-seq

2018

Journal Article

Evidence for minimal cardiogenic potential of stem cell sntigen 1-positive cells in the adult mouse heart

Neidig, Lauren E., Weinberger, Florian, Palpant, Nathan J., Mignone, John, Martinson, Amy M., Sorensen, Daniel W., Bender, Ingrid, Nemoto, Natsumi, Reinecke, Hans, Pabon, Lil, Molkentin, Jeffery D., Murry, Charles E. and van Berlo, Jop H. (2018). Evidence for minimal cardiogenic potential of stem cell sntigen 1-positive cells in the adult mouse heart. Circulation, 138 (25), 2960-2962. doi: 10.1161/CIRCULATIONAHA.118.035273

Evidence for minimal cardiogenic potential of stem cell sntigen 1-positive cells in the adult mouse heart

2018

Journal Article

Genetic lineage tracing of Sca-1 cells reveals endothelial but not myogenic contribution to the murine heart

Vagnozzi, Ronald J., Sargent, Michelle A., Lin, Suh-Chin J., Palpant, Nathan J., Murry, Charles E. and Molkentin, Jeffery D. (2018). Genetic lineage tracing of Sca-1 cells reveals endothelial but not myogenic contribution to the murine heart. Circulation, 138 (25), CIRCULATIONAHA.118.035210-2939. doi: 10.1161/CIRCULATIONAHA.118.035210

Genetic lineage tracing of Sca-1 cells reveals endothelial but not myogenic contribution to the murine heart