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2024

Conference Publication

Improved recovery of rat hearts after prolonged cold storage by acid sensing ion channel (ASIC) inhibitor Hi1a varies with preservation solution

Dutta, Sanjay, Villanueva, Jeanette E., Gao, Ling, Doyle, Aoife, Palpant, Nathan, King, Glenn and Macdonald, Peter S. (2024). Improved recovery of rat hearts after prolonged cold storage by acid sensing ion channel (ASIC) inhibitor Hi1a varies with preservation solution. 30th International Congress of The Transplantation-Society (TTS), Istanbul, Turkey, 22-25 September 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Improved recovery of rat hearts after prolonged cold storage by acid sensing ion channel (ASIC) inhibitor Hi1a varies with preservation solution

2024

Conference Publication

Improved recovery of rat hearts after prolonged cold storage by acid sensing ion channel (ASIC) inhibitor Hi1a varies with preservation solution

Dutta, Sanjay, Villanueva, Jeanette E., Gao, Ling, Doyle, Aoife, Palpant, Nathan, King, Glenn and Macdonald, Peter S. (2024). Improved recovery of rat hearts after prolonged cold storage by acid sensing ion channel (ASIC) inhibitor Hi1a varies with preservation solution. 30th International Congress of the Transplantation Society, Istanbul, Turkey, 22-25 September 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0001066648.27486.ce

Improved recovery of rat hearts after prolonged cold storage by acid sensing ion channel (ASIC) inhibitor Hi1a varies with preservation solution

2024

Conference Publication

Mending achy-breaky hearts: cyclic peptide TL01 is an enhancer of cardiac intracellular protein-protein interactions and promotes heart contractility

Rojas-Azofeifa, Daniela, Passioura, Toby, McMillen, Timothy, Cheesman, Elisabeth, Saez, Natalie, Chow, Jonathan, Eagles, David, Norman, Alexander, Perry, Matthew, Molenar, Peter, Regnier, Michael, King, Glenn and Palpant, Nathan (2024). Mending achy-breaky hearts: cyclic peptide TL01 is an enhancer of cardiac intracellular protein-protein interactions and promotes heart contractility. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons.

Mending achy-breaky hearts: cyclic peptide TL01 is an enhancer of cardiac intracellular protein-protein interactions and promotes heart contractility

2024

Conference Publication

Preclinical models of Glycaemic variability recapitulate Clinical Cardiovascular outcomes in Diabetes

Cao, Y., Redd, M., Outhwaite, J., Shim, W., Fang, C., Negi, S., Shen, S., Mizikovsky, D., Chiu, H., Tan, C., Thomas, U., Dragicevic, E., Sng, J., Short, K. and Palpant, N. (2024). Preclinical models of Glycaemic variability recapitulate Clinical Cardiovascular outcomes in Diabetes. 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.332

Preclinical models of Glycaemic variability recapitulate Clinical Cardiovascular outcomes in Diabetes

2024

Conference Publication

Trastuzumab-Induced Cardiotoxicity Involves Antibody Dependent Cell Cytotoxicity (ADCC)

Griffiths, L., Ho, U., Burt, K., Watson, S., Patel, K., Bradford, J., Tan, C., Bhavsar, C., Palpant, N., Souza-Fonseca-Guimaraes, F., Wu, S., Reichelt, M. and Thomas, W. (2024). Trastuzumab-Induced Cardiotoxicity Involves Antibody Dependent Cell Cytotoxicity (ADCC). 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.397

Trastuzumab-Induced Cardiotoxicity Involves Antibody Dependent Cell Cytotoxicity (ADCC)

2024

Conference Publication

Dissecting the Role of Hopx Variants in Cardiac Remodelling and Dysfunction

Hanna, A., Negi, S., Outhwaite, J., Cheng, T., Tan, C., Chen, J., Fatkin, D., Haas, J. and Palpant, N. (2024). Dissecting the Role of Hopx Variants in Cardiac Remodelling and Dysfunction. International Clinical Cardiovascular Genetics Conference 2024, Brisbane, QLD Australia, 8-10 May 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.04.189

Dissecting the Role of Hopx Variants in Cardiac Remodelling and Dysfunction

2024

Other Outputs

Cell cultures and methods of use thereof

Hewitt, Alex, Powell, Joseph, Neavin, Drew, Farbehi, Nona, Pebay, Alice, Daniszewski, Maciej and Palpant, Nathan (2024). Cell cultures and methods of use thereof. 2023901013.

Cell cultures and methods of use thereof

2024

Journal Article

High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms

Kramer, Simon, Kotapati, Charan, Cao, Yuanzhao, Fry, Bryan G., Palpant, Nathan J., King, Glenn F. and Cardoso, Fernanda C. (2024). High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms. Toxicon: X, 21 100184, 100184. doi: 10.1016/j.toxcx.2024.100184

High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms

2024

Journal Article

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, Dinesh, Clayton, Zoe E., Prowse, Andrew, Dingwall, Steve, Kim, Sul Ki, Reyes, Leila, George, Jacob, Shah, Haisam, Chen, Siqi, Leung, Halina H. L., Hume, Robert D., Tjahjadi, Laurentius, Igoor, Sindhu, Skelton, Rhys J. P., Hing, Alfred, Paterson, Hugh, Foster, Sheryl L., Pearson, Lachlan, Wilkie, Emma, Marcus, Alan D., Jeyaprakash, Prajith, Wu, Zhixuan, Chiu, Han Shen, Ongtengco, Cherica Felize J., Mulay, Onkar, McArthur, Jeffrey R., Barry, Tony, Lu, Juntang, Tran, Vu ... Chong, James J. H. (2024). Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. Nature Cardiovascular Research, 3 (2), 145-165. doi: 10.1038/s44161-023-00419-3

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

2024

Conference Publication

How the Australian Functional Genomics Network (AFGN) contributes to improved patient care

Scott, Hamish S., Matotek, Ebony, Mattiske, Tessa, Bryson-Richardson, Robert J., Smyth, Ian, Gecz, Jozef, Christodoulou, John, Palpant, Nathan, Smith, Kelly, Warr, Coral, Bennetts, Bruce, Thomas, Paul, Bowles, Josephine, Hilliard, Massimo, Hime, Gary, Hool, Livia, Quinn, Leonie, Wolvetang, Ernst, Jamieson, Robyn, Baynam, Gareth, Dudding-Byth, Tracy, Tan, Tiong Yang, Milnes, Di, Wallis, Mathew, Palmer, Elizabeth, Patel, Chirag, Jones, Kristi, Tam, Patrick, Stark, Zornitza ... Sinclair, Andrew (2024). How the Australian Functional Genomics Network (AFGN) contributes to improved patient care. Pathology Update 2024, Adelaide, SA, Australia, 1-3 March 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2023.12.084

How the Australian Functional Genomics Network (AFGN) contributes to improved patient care

2023

Conference Publication

Disease modeling utilizing human pluripotent stem cell-derived cardiomyocytes and physiological characterization

Cao, Yuanzhao, Redd, Meredith A., Shim, Woo Jun, Fang, Chen, Chiu, Han, Azofeifa, Daniela Rojas, Thomas, Ulrich, Lemme, Marta, Dragicevic, Elena, Stoelzle-Feix, Sonja and Palpant, Nathan J. (2023). Disease modeling utilizing human pluripotent stem cell-derived cardiomyocytes and physiological characterization. Safety Pharmacology Society Annual Meeting, Brussels, Belgium, 18-21 September 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.vascn.2023.107267

Disease modeling utilizing human pluripotent stem cell-derived cardiomyocytes and physiological characterization

2023

Journal Article

A village in a dish model system for population-scale hiPSC studies

Neavin, Drew R., Steinmann, Angela M., Farbehi, Nona, Chiu, Han Sheng, Daniszewski, Maciej S., Arora, Himanshi, Bermudez, Yasmin, Moutinho, Cátia, Chan, Chia-Ling, Bax, Monique, Tyebally, Mubarika, Gnanasambandapillai, Vikkitharan, Lam, Chuan E., Nguyen, Uyen, Hernández, Damián, Lidgerwood, Grace E., Graham, Robert M., Hewitt, Alex W., Pébay, Alice, Palpant, Nathan J. and Powell, Joseph E. (2023). A village in a dish model system for population-scale hiPSC studies. Nature Communications, 14 (1) 3240, 1-12. doi: 10.1038/s41467-023-38704-1

A village in a dish model system for population-scale hiPSC studies

2023

Journal Article

Vascular cells improve functionality of human cardiac organoids

Voges, Holly K., Foster, Simon R., Reynolds, Liam, Parker, Benjamin L., Devilée, Lynn, Quaife-Ryan, Gregory A., Fortuna, Patrick R.J., Mathieson, Ellen, Fitzsimmons, Rebecca, Lor, Mary, Batho, Christopher, Reid, Janice, Pocock, Mark, Friedman, Clayton E., Mizikovsky, Dalia, Francois, Mathias, Palpant, Nathan J., Needham, Elise J., Peralta, Marina, Monte-Nieto, Gonzalo del, Jones, Lynelle K., Smyth, Ian M., Mehdiabadi, Neda R., Bolk, Francesca, Janbandhu, Vaibhao, Yao, Ernestene, Harvey, Richard P., Chong, James J.H., Elliott, David A. ... Hudson, James E. (2023). Vascular cells improve functionality of human cardiac organoids. Cell Reports, 42 (5) 112322, 1-22. doi: 10.1016/j.celrep.2023.112322

Vascular cells improve functionality of human cardiac organoids

2023

Journal Article

New drug targets and preclinical modelling recommendations for treating acute myocardial infarction

Cao, Yuanzhao, Redd, Meredith A., Fang, Chen, Mizikovsky, Dalia, Li, Xichun, Macdonald, Peter S., King, Glenn F. and Palpant, Nathan J. (2023). New drug targets and preclinical modelling recommendations for treating acute myocardial infarction. Heart, Lung and Circulation, 32 (7), 852-869. doi: 10.1016/j.hlc.2022.12.015

New drug targets and preclinical modelling recommendations for treating acute myocardial infarction

2023

Conference Publication

Improving asystolic warm ischemic time tolerance in donation after circulatory death donor hearts

Joshi, Y., Villanueva, J., Gao, L., Hwang, B., Wang, K., Kasavaraj, A., Doyle, A., Wu, J., Palpant, N., King, G., Iyer, A., Jansz, P. and MacDonald, P. (2023). Improving asystolic warm ischemic time tolerance in donation after circulatory death donor hearts. 43rd Annual Meeting of International Society for Heart and Lung Transplantation (ISHLT), Denver, CO United States, 19-22 April 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2023.02.878

Improving asystolic warm ischemic time tolerance in donation after circulatory death donor hearts

2023

Journal Article

PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction

Hume, Robert D., Deshmukh, Tejas, Doan, Tram, Shim, Woo Jun, Kanagalingam, Shaan, Tallapragada, Vikram, Rashid, Fairooj, Marcuello, Maria, Blessing, Daniel, Selvakumar, Dinesh, Raguram, Kalyan, Pathan, Faraz, Graham, Dinny, Ounzain, Samir, Kizana, Eddy, Harvey, Richard P., Palpant, Nathan J. and Chong, James J.H. (2023). PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction. JACC: Basic to Translational Science, 8 (6), 658-674. doi: 10.1016/j.jacbts.2022.11.006

PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction

2023

Journal Article

Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation

Alavattam, Kris G., Mitzelfelt, Katie A., Bonora, Giancarlo, Fields, Paul A., Yang, Xiulan, Chiu, Han Sheng, Pabon, Lil, Bertero, Alessandro, Palpant, Nathan J., Noble, William S. and Murry, Charles E. (2023). Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation. Stem Cell Reports, 18 (1), 159-174. doi: 10.1016/j.stemcr.2022.11.003

Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation

2023

Journal Article

A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification

Plaisance, Isabelle, Chouvardas, Panagiotis, Sun, Yuliangzi, Nemir, Mohamed, Aghagolzadeh, Parisa, Aminfar, Farhang, Shen, Sophie, Shim, Woo Jun, Rochais, Francesca, Johnson, Rory, Palpant, Nathan and Pedrazzini, Thierry (2023). A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification. Cardiovascular Research, 119 (6), 1361-1376. doi: 10.1093/cvr/cvac191

A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification

2022

Conference Publication

H3K27me3 predicted regulation of gene expression linked to calcium quantification in Nelore muscle

Afonso, J., Shim, W.J., Boden, M., Palpant, N., Fortes, M.R.S., Diniz, W.J.S., Lima, A.O., Rocha, M.I.P., Cardoso, T.F., Bruscadin, J.J., Gromboni, C.F., Nogueira, A.R.A., Mourão, G.B., Zerlotini, A., Coutinho, L.L. and Regitano, L.C.A. (2022). H3K27me3 predicted regulation of gene expression linked to calcium quantification in Nelore muscle. 12th World Congress on Genetics Applied to Livestock Production (WCGALP), Rotterdam, Netherlands, 3-8 July 2022. Wageningen, Netherlands: Wageningen Academic Publishers. doi: 10.3920/978-90-8686-940-4_553

H3K27me3 predicted regulation of gene expression linked to calcium quantification in Nelore muscle

2022

Other Outputs

Methods and compositions for multiplexing cell analysis

Palpant, Nathan, Anderson, Stacey, Werner, Tessa, Lukowski, Samuel and Shen, Sophie (2022). Methods and compositions for multiplexing cell analysis. PCT/AU2022/051476.

Methods and compositions for multiplexing cell analysis