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2017

Journal Article

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

Muttenthaler, Markus, Andersson, Asa, Vetter, Irina, Menon, Rohit, Busnelli, Marta, Ragnarsson, Lotten, Bergmayr, Christian, Arrowsmith, Sarah, Deuis, Jennifer R., Chiu, Han Sheng, Palpant, Nathan J., O'Brien, Margaret, Smith, Terry J., Wray, Susan, Neumann, Inga D., Gruber, Christian W., Lewis, Richard J. and Alewood, Paul F. (2017). Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling, 10 (508) eaan3398, 1-13. doi: 10.1126/scisignal.aan3398

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

2017

Journal Article

A transcribed enhancer dictates mesendoderm specification in pluripotency

Alexanian, Michael, Maric, Daniel, Jenkinson, Stephen P., Mina, Marco, Friedman, Clayton E., Ting, Ching-Chia, Micheletti, Rudi, Plaisance, Isabelle, Nemir, Mohamed, Maison, Damien, Kernen, Jasmin, Pezzuto, Iole, Villeneuve, Dominic, Burdet, Frederic, Ibberson, Mark, Leib, Stephen L., Palpant, Nathan J., Hernandez, Nouria, Ounzain, Samir and Pedrazzini, Thierry (2017). A transcribed enhancer dictates mesendoderm specification in pluripotency. Nature Communications, 8 (1) 1806, 1-19. doi: 10.1038/s41467-017-01804-w

A transcribed enhancer dictates mesendoderm specification in pluripotency

2017

Journal Article

Chromatin and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a regulator of primitive hematopoiesis

Palpant, Nathan J., Wang, Yuliang, Hadland, Brandon, Zaunbrecher, Rebecca J., Redd, Meredith, Jones, Daniel, Pabon, Lil, Jain, Rajan, Epstein, Jonathan, Ruzzo, Walter L., Zheng, Ying, Bernstein, Irwin, Margolin, Adam and Murry, Charles E. (2017). Chromatin and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a regulator of primitive hematopoiesis. Cell Reports, 20 (7), 1597-1608. doi: 10.1016/j.celrep.2017.07.067

Chromatin and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a regulator of primitive hematopoiesis

2017

Journal Article

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta

Zamir, Lyad, Singh, Reena, Nathan, Elisha, Patrick, Ralph, Yifa, Oren, Yahalom-Ronen, Yfat, Arrafi, Alaa A., Schultheiss, Thomas M., Suo, Shengbao, Han, Jing-Dong Jackie, Peng, Guangdun, Jing, Naihe, Wang, Yuliang, Palpant, Nathan, Tam, Patrick P. L., Harveyz, Richard P. and Tzahor, Eldad (2017). Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta. ELife, 6 e20994. doi: 10.7554/eLife.20994

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta

2017

Journal Article

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

Palpant, Nathan J., Pabon, Lil, Friedman, Clayton E., Roberts, Meredith, Hadland, Brandon, Zaunbrecher, Rebecca J., Bernstein, Irwin, Zheng, Ying and Murry, Charles E. (2017). Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells. Nature Protocols, 12 (1), 15-31. doi: 10.1038/nprot.2016.153

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

2017

Conference Publication

Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium

Palpant, Nathan, Wang, Yuliang, Hadland, Brandon, Zaunbrecher, Rebecca, Redd, Meredith, Pabon, Lil, Jain, Rajan, Epstein, Jonathan, Zheng, Ying, Bernstein, Irwin, Margolin, Adam and Murry, Charles (2017). Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium. 18th International Congress of Developmental Biology, Singapore, Singapore, 18 - 22 June 2017. E Park, Shannon, Clare Ireland: Elsevier Ireland. doi: 10.1016/j.mod.2017.04.263

Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium

2016

Journal Article

Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5

Szabo, Linda, Morey, Robert, Palpant, Nathan J., Wang, Peter L., Afari, Nastaran, Jiang, Chuan, Parast, Mana M., Murry, Charles E., Laurent, Louise C. and Salzman, Julia (2016). Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5. Genome Biology, 17 (1) 263. doi: 10.1186/s13059-016-1123-9

Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development [Genome Biology, 16, (2016) (126)], DOI: 10.1186/s13059-015-0690-5

2016

Journal Article

The developmental origins and lineage contributions of endocardial endothelium

Nakano, Atsushi, Nakano, Haruko, Smith, Kelly A. and Palpant, Nathan J. (2016). The developmental origins and lineage contributions of endocardial endothelium. Biochimica et Biophysica Acta. Molecular Cell Research, 1863 (7), 1937-1947. doi: 10.1016/j.bbamcr.2016.01.022

The developmental origins and lineage contributions of endocardial endothelium

2015

Journal Article

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

Szabo, Linda, Morey, Robert, Palpant, Nathan J., Wang, Peter L., Afari, Nastaran, Jiang, Chuan, Parast, Mana M., Murry, Charles E., Laurent, Louise C. and Salzman, Julia (2015). Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development. Genome Biology, 16 (1) 126. doi: 10.1186/s13059-015-0690-5

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

2015

Journal Article

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

Palpant, Nathan J., Hofsteen, Peter, Pabon, Lil, Reinecke, Hans and Murry, Charles E. (2015). Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes. PLoS ONE, 10 (5) 0126259, e0126259.1-e0126259. 19. doi: 10.1371/journal.pone.0126259

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and ecigarettes

2015

Conference Publication

Elevated microjet gradient device for directing spatiotemporal differentiation of embryonic stem cells

Bhattacharjee, N., Palpant, N. J., Murry, C. E. and Folch, A. (2015). Elevated microjet gradient device for directing spatiotemporal differentiation of embryonic stem cells. MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2015, Gyeongju, South Korea, 25-29 October 2015. San Diego, CA United States: Chemical and Biological Microsystems Society.

Elevated microjet gradient device for directing spatiotemporal differentiation of embryonic stem cells

2015

Journal Article

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

Palpant, Nathan J., Pabon, Lil, Roberts, Meredith, Hadland, Brandon, Jones, Daniel, Jones, Christina, Moon, Randall T., Ruzzo, Walter L., Bernstein, Irwin, Zheng, Ying and Murry, Charles E. (2015). Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes. Development (Cambridge), 142 (18), 3198-3209. doi: 10.1242/dev.117010

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

2014

Journal Article

Proliferation at the heart of preadolescence

Palpant, Nathan J. and Murry, Charles E. (2014). Proliferation at the heart of preadolescence. Cell, 157 (4), 765-767. doi: 10.1016/j.cell.2014.04.025

Proliferation at the heart of preadolescence

2014

Book Chapter

Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts

Zhu, Wei-Zhong, Filice, Dominic, Palpant, Nathan J. and Laflamme, Michael A. (2014). Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts. Cardiac tissue engineering: methods and protocols. (pp. 229-247) edited by Radisci, Milica and Black III, Lauren D.. New York, NY United States: Springer New York. doi: 10.1007/978-1-4939-1047-2_20

Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts

2014

Journal Article

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

Chong, James J. H., Yang, Xiulan, Don, Creighton W., Minami, Elina, Liu, Yen-Wen, Weyers, Jill J., Mahoney, William M., Van Biber, Benjamin, Cook, Savannah M., Palpant, Nathan J., Gantz, Jay A., Fugate, James A., Muskheli, Veronica, Gough, G. Michael, Vogel, Keith W., Astley, Cliff A., Hotchkiss, Charlotte E., Baldessari, Audrey, Pabon, Lil, Reinecke, Hans, Gill, Edward A., Nelson, Veronica, Kiem, Hans-Peter, Laflamme, Michael A. and Murry, Charles E. (2014). Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature, 510 (7504), 273-277. doi: 10.1038/nature13233

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

2013

Conference Publication

Transmembrane Protein 88: A Wnt Regulatory Protein That Specifies Cardiomyocyte Development

Palpant, Nathan, Pabon, Lil, Rabinowitz, Jeremy, Hadland, Brandon, Stoick-Cooper, Cristi, Paige, Sharon, Bernstein, Irwin, Moon, Randall and Murry, Charles (2013). Transmembrane Protein 88: A Wnt Regulatory Protein That Specifies Cardiomyocyte Development. Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association, Dallas Tx, Nov 16-17, 2013. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Transmembrane Protein 88: A Wnt Regulatory Protein That Specifies Cardiomyocyte Development

2013

Journal Article

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

Palpant, Nathan J., Pabon, Lil, Rabinowitz, Jeremy S., Hadland, Brandon K., Stoick-Cooper, Cristi L., Paige, Sharon L., Bernstein, Irwin D., Moon, Randall T. and Murry, Charles E. (2013). Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development. Development (Cambridge), 140 (18), 3799-3808. doi: 10.1242/dev.094789

Transmembrane protein 88: A Wnt regulatory protein that specifies cardiomyocyte development

2013

Journal Article

Cardiopoietry in motion

Murry, Charles E., Palpant, Nathan J. and MacLellan, W. Robb (2013). Cardiopoietry in motion. Journal of the American College of Cardiology, 61 (23), 2339-2340. doi: 10.1016/j.jacc.2013.03.028

Cardiopoietry in motion

2013

Book Chapter

Human dignity in the throes?: An introduction to the volume

Dilley, Stephen and Palpant, Nathan J. (2013). Human dignity in the throes?: An introduction to the volume. Human Dignity in Bioethics: From Worldviews to the Public Square. (pp. 3-18) New York, NY United States: Taylor and Francis. doi: 10.4324/9780203075005

Human dignity in the throes?: An introduction to the volume

2013

Book

Human dignity in bioethics: From worldviews to the public square

Dilley, Stephen and Palpant, Nathan J. (2013). Human dignity in bioethics: From worldviews to the public square. New York, United States: Routledge. doi: 10.4324/9780203075005

Human dignity in bioethics: From worldviews to the public square