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2015 Journal Article Genome-wide genetic homogeneity between sexes and populations for human height and body mass indexYang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A. E., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, Study, Lifelines Cohort, Esko, Tonu, Milani, Lili, Maegi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K. E., Pedersen, Nancy L., Ingelsson, Erik and Visscher, Peter M. (2015). Genome-wide genetic homogeneity between sexes and populations for human height and body mass index. Human Molecular Genetics, 24 (25), 7445-7449. doi: 10.1093/hmg/ddv443 |
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2015 Journal Article Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysisLoh, Po-Ru, Bhatia, Gaurav, Gusev, Alexander, Finucane, Hilary K., Bulik-Sullivan, Brendan K., Pollack, Samuela J., de Candia, Teresa R., Lee, Sang Hong, Wray, Naomi R., Kendler, Kenneth S., O'Donovan, Michael C., Neale, Benjamin M., Patterson, Nick, Price, Alkes L., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Visscher, Peter M. and Mowry, Bryan J. (2015). Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. Nature Genetics, 47 (12), 1385-1392. doi: 10.1038/ng.3431 |
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2015 Journal Article The transcriptional landscape of age in human peripheral bloodPeters, Marjolein J., Joehanes, Roby, Pilling, Luke C., Schurmann, Claudia, Conneely, Karen N., Powell, Joseph, Reinmaa, Eva, Sutphin, George L., Zhernakova, Alexandra, Schramm, Katharina, Wilson, Yana A., Kobes, Sayuko, Tukiainen, Taru, Ramos, Yolande F., Goring, Harald H. H., Fornage, Myriam, Liu, Yongmei, Gharib, Sina A., Stranger, Barbara E., De Jager, Philip L., Aviv, Abraham, Levy, Daniel, Murabito, Joanne M., Munson, Peter J., Huan, Tianxiao, Hofman, Albert, Uitterlinden, Andre G., Rivadeneira, Fernando, Van Rooij, Jeroen ... NABEC/UKBEC Consortium (2015). The transcriptional landscape of age in human peripheral blood. Nature Communications, 6 (1) 8570, 8570.1-8570.14. doi: 10.1038/ncomms9570 |
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2015 Journal Article Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk ScoresVilhjalmsson, Bjarni J., Yang, Jian, Finucane, Hilary K., Gusev, Alexander, Lindstrom, Sara, Ripke, Stephan, Genovese, Giulio, Loh, Po-Ru, Bhatia, Gaurav, Do, Ron, Hayeck, Tristan, Won, Hong-Hee, Kathiresan, Sekar, Pato, Michele, Pato, Carlos, Tamimi, Rulla, Stahl, Eli, Zaitlen, Noah, Pasaniuc, Bogdan, Belbin, Gillian, Kenny, Eimear E., Schierup, Mikkel H., De Jager, Philip, Patsopouos, Nikolaos A., Mc Carroll, Steve, Daly, Mark, Purce, Shaun, Chasman, Daniel, Neale, Benjamin ... Price, Alkes L. (2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics, 97 (4), 576-592. doi: 10.1016/j.ajhg.2015.09.001 |
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2015 Journal Article The UK10K project identifies rare variants in health and diseaseThe UK10K Consortium, Evans, David M., Kemp, John P., Visscher, Peter M. and Yang, Jian (2015). The UK10K project identifies rare variants in health and disease. Nature, 526 (7571), 82-89. doi: 10.1038/nature14962 |
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2015 Journal Article Genome-wide autozygosity is associated with lower general cognitive abilityHowrigan, D.P., Simonson, M.A., Davies, G., Harris, S.E., Tenesa, A., Starr, J.M., Liewald, D.C., Deary, I.J., McRae, A., Wright, M.J., Montgomery, G.W., Hansell, N., Martin, N.G., Payton, A., Horan, M., Ollier, W.E., Abdellaoui, A., Boomsma, D.I., DeRosse, P., Knowles, E.E.M., Glahn, D.C., Djurovic, S., Melle, I., Andreassen, O.A., Christoforou, A., Steen, V.M., Hellard, S.L., Sundet, K., Reinvang, I. ... Keller, M.C. (2015). Genome-wide autozygosity is associated with lower general cognitive ability. Molecular Psychiatry, 21 (6), 837-843. doi: 10.1038/mp.2015.120 |
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2015 Journal Article Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panelHuang, Jie, Howie, Bryan, McCarthy, Shane, Memari, Yasin, Walter, Klaudia, Min, Josine L., Danecek, Petr, Malerba, Giovanni, Trabetti, Elisabetta, Zheng, Hou-Feng, Gambaro, Giovanni, Richards, J. Brent, Durbin, Richard, Timpson, Nicholas J., Marchini, Jonathan, Soranzo, Nicole, UK10K Consortium, Evans, David M., Kemp, John P., Visscher, Peter M. and Yang, Jian (2015). Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel. Nature Communications, 6 (1) 8111, 8111.1-8111.9. doi: 10.1038/ncomms9111 |
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2015 Journal Article Population genetic differentiation of height and body mass index across EuropeRobinson, Matthew R., Hemani, Gibran, Medina-Gomez, Carolina, Mezzavilla, Massimo, Esko, Tonu, Shakhbazov, Konstantin, Powell, Joseph E., Vinkhuyzen, Anna, Berndt, Sonja I., Gustafsson, Stefan, Justice, Anne E., Kahali, Bratati, Locke, Adam E., Pers, Tune H., Vedantam, Sailaja, Wood, Andrew R., van Rheenen, Wouter, Andreassen, Ole A., Gasparini, Paolo, Metspalu, Andres, van den Berg, Leonard H., Veldink, Jan H., Rivadeneira, Fernando, Werge, Thomas M., Abecasis, Goncalo R., Boomsma, Dorret I., Chasman, Daniel I., de Geus, Eco J. C., Frayling, Timothy M. ... Visscher, Peter M. (2015). Population genetic differentiation of height and body mass index across Europe. Nature Genetics, 47 (11), 1357-1361. doi: 10.1038/ng.3401 |
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2015 Journal Article 3-D Facial Landmark Localization With Asymmetry Patterns and Shape Regression from Incomplete Local FeaturesSukno, Federico M., Waddington, John L. and Whelan, Paul F. (2015). 3-D Facial Landmark Localization With Asymmetry Patterns and Shape Regression from Incomplete Local Features. Ieee Transactions On Cybernetics, 45 (9), 1717-1730. doi: 10.1109/TCYB.2014.2359056 |
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2015 Journal Article Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass indexYang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A. E., Lee, Sang Hong, Robinson, Matthew R., Perry, John R. B., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, The LifeLines Cohort Study, Esko, Tonu, Milani, Lili, Maegi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K. E., Pedersen, Nancy L., Ingelsson, Erik, Soranzo, Nicole, Keller, Matthew C., Wray, Naomi R., Goddard, Michael E. and Visscher, Peter M. (2015). Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index. Nature Genetics, 47 (10), 1114-1120. doi: 10.1038/ng.3390 |
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2015 Journal Article The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936Marioni, Riccardo E., Shah, Sonia, McRae, Allan F., Ritchie, Stuart J., Muniz-Terrera, Graciela, Harris, Sarah E., Gibson, Jude, Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Taylor, Adele, Murphy, Lee, Starr, John M., Horvath, Steve, Visscher, Peter M., Wray, Naomi R. and Deary, Ian J. (2015). The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. International Journal of Epidemiology, 44 (4), 1388-1396. doi: 10.1093/ije/dyu277 |
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2015 Journal Article The association between intelligence and lifespan is mostly geneticArden, Rosalind, Luciano, Michelle, Deary, Ian J., Reynolds, Chandra A., Pedersen, Nancy L., Plassman, Brenda L., McGue, Matt, Christensen, Kaare and Visscher, Peter M. (2015). The association between intelligence and lifespan is mostly genetic. International Journal of Epidemiology, 45 (1), 178-185. doi: 10.1093/ije/dyv112 |
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2015 Journal Article Improving phenotypic prediction by combining genetic and epigenetic associationsShah, Sonia, Bonder, Marc J., Marioni, Riccardo E., Zhu, Zhihong, McRae, Allan F., Zhernakova, Alexandra, Harris, Sarah E., Liewald, Dave, Henders, Anjali K., Mendelson, Michael M., Liu, Chunyu, Joehanes, Roby, Liang, Liming, Levy, Daniel, Martin, Nicholas G., Starr, John M., Wijmenga, Cisca, Wray, Naomi R., Yang, Jian, Montgomery, Grant W., Franke, Luke, Deary, Ian J., Visscher, Peter M. and BIOS Consortium (2015). Improving phenotypic prediction by combining genetic and epigenetic associations. American Journal of Human Genetics, 97 (1), 75-85. doi: 10.1016/j.ajhg.2015.05.014 |
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2015 Journal Article Genetic variation links creativity to psychiatric disordersKeller, Matthew C. and Visscher, Peter M. (2015). Genetic variation links creativity to psychiatric disorders. Nature Neuroscience, 18 (7), 928-929. doi: 10.1038/nn.4047 |
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2015 Journal Article C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosisHe, Ji, Tang, Lu, Benyamin, Beben, Shah, Sonia, Hemani, Gib, Liu, Rong, Ye, Shan, Liu, Xiaolu, Ma, Yan, Zhang, Huagang, Cremin, Katie, Leo, Paul, Wray, Naomi R., Visscher, Peter M., Xu, Huji, Brown, Matthew A., Bartlett, Perry F., Mangelsdorf, Marie and Fan, Dongsheng (2015). C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosis. Neurobiology of Aging, 36 (9) 2660.e1, 2660.e1-2660.e8. doi: 10.1016/j.neurobiolaging.2015.06.002 |
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2015 Journal Article Shared genetics underlying epidemiological association between endometriosis and ovarian cancerLu, Yi, Cuellar-Partida, Gabriel, Painter, Jodie N., Nyholt, Dale R., Morris, Andrew P., Fasching, Peter A., Hein, Alexander, Burghaus, Stefanie, Beckmann, Matthias W., Lambrechts, Diether, Van Nieuwenhuysen, Els, Vergote, Ignace, Vanderstichele, Adriaan, Doherty, Jennifer Anne, Rossing, Mary Anne, Wicklund, Kristine G., Chang-Claude, Jenny, Eilber, Ursula, Rudolph, Anja, Wang-Gohrke, Shan, Goodman, Marc T., Bogdanova, Natalia, Doerk, Thilo, Duerst, Matthias, Hillemanns, Peter, Runnebaum, Ingo B., Antonenkova, Natalia, Butzow, Ralf, Leminen, Arto ... Visscher, Peter M. (2015). Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. Human Molecular Genetics, 24 (20), 5955-5964. doi: 10.1093/hmg/ddv306 |
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2015 Journal Article Human fertility, molecular genetics, and natural selection in modern societiesTropf, Felix C., Stulp, Gert, Barban, Nicola, Visscher, Peter M., Yang, Jian, Snieder, Harold and Mills, Melinda C. (2015). Human fertility, molecular genetics, and natural selection in modern societies. Plos One, 10 (6) e0126821, 1-14. doi: 10.1371/journal.pone.0126821 |
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2015 Journal Article Meta-analysis of the heritability of human traits based on fifty years of twin studiesPolderman, Tinca J. C., Benyamin, Beben, de Leeuw, Christiaan A, Sullivan, Patrick F., van Bochoven, Arjen, Visscher, Peter M. and Posthuma, Danielle (2015). Meta-analysis of the heritability of human traits based on fifty years of twin studies. Nature Genetics, 47 (7), 702-709. doi: 10.1038/ng.3285 |
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2015 Journal Article Mixed model with correction for case-control ascertainment increases association powerHayeck, Tristan J., Zaitlen, Noah A., Loh, Po-Ru, Vilhjalmsson, Bjarni, Pollack, Samuela, Gusev, Alexander, Yang, Jian, Chen, Guo-Bo, Goddard, Michael E., Visscher, Peter M., Patterson, Nick and Price, Alkes L. (2015). Mixed model with correction for case-control ascertainment increases association power. American Journal of Human Genetics, 96 (5), 720-730. doi: 10.1016/j.ajhg.2015.03.004 |
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2015 Journal Article Simultaneous discovery, estimation and prediction analysis of complex traits using a bayesian mixture modelMoser, Gerhard, Lee, Sang Hong, Hayes, Ben J., Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2015). Simultaneous discovery, estimation and prediction analysis of complex traits using a bayesian mixture model. PLoS Genetics, 11 (4) e1004969, 1-22. doi: 10.1371/journal.pgen.1004969 |
