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2014

Journal Article

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Graham, Robert R., Manoharan, Arun, Ortmann, Ward, Bhangale, Tushar, Denny, Joshua C., Carroll, Robert J., Eyler, Anne E., Greenberg, Jeffrey D., Kremer, Joel M., Pappas, Dimitrios A., Jiang, Lei, Yin, Jian, Ye, Lingying, Su, Ding-Feng, Yang, Jian, Xie, Gang, Keystone, Ed, Westra, Harm-Jan, Esko, Tonu ... Brown, Matthew A. (2014). Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature, 506 (7488), 376-381. doi: 10.1038/nature12873

Genetics of rheumatoid arthritis contributes to biology and drug discovery

2014

Journal Article

Common genetic variants explain the majority of the correlation between height and intelligence: The generation scotland study

Marioni, Riccardo E., Batty, G. David, Hayward, Caroline, Kerr, Shona M., Campbell, Archie, Hocking, Lynne J., Porteous, David J., Visscher, Peter M. and Deary, Ian J. (2014). Common genetic variants explain the majority of the correlation between height and intelligence: The generation scotland study. Behavior Genetics, 44 (2), 91-96. doi: 10.1007/s10519-014-9644-z

Common genetic variants explain the majority of the correlation between height and intelligence: The generation scotland study

2014

Journal Article

Novel risk loci for rheumatoid arthritis in han chinese and congruence with risk variants in europeans

Jiang, Lei, Yin, Jian, Ye, Lingying, Yang, Jian, Hemani, Gibran, Liu, Ai-Jun, Zou, Hejian, He, Dongyi, Sun, Lingyun, Zeng, Xiaofeng, Li, Zhanguo, Zheng Yi, Lin, Yiping, Liu, Yi, Fang, Yongfei, Xu, Jianhua, Li, Yinong, Dai, Shengming, Guan, Jianlong, Jiang, Lindi, Wei, Qianghua, Wang, Yi, Li, Yang, Huang, Cibo, Zuo, Xiaoxia, Liu, Yu, Wu, Xin, Zhang, Libin, Zhou, Ling ... Xu, Huji (2014). Novel risk loci for rheumatoid arthritis in han chinese and congruence with risk variants in europeans. Arthritis and Rheumatology, 66 (5), 1121-1132. doi: 10.1002/art.38353

Novel risk loci for rheumatoid arthritis in han chinese and congruence with risk variants in europeans

2014

Journal Article

Changing Microspatial Patterns of SulfateReducing Microorganisms (SRM) during Cycling of Marine Stromatolite Mats

Petrisor, Alexandru I., Szyjka, Sandra, Kawaguchi, Tomohiro, Visscher, Pieter T., Norman, Robert Sean and Decho, Alan W. (2014). Changing Microspatial Patterns of SulfateReducing Microorganisms (SRM) during Cycling of Marine Stromatolite Mats. International Journal of Molecular Sciences, 15 (1), 850-877. doi: 10.3390/ijms15010850

Changing Microspatial Patterns of SulfateReducing Microorganisms (SRM) during Cycling of Marine Stromatolite Mats

2014

Journal Article

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

Visscher, Peter M., Hemani, Gibran, Vinkhuyzen, Anna A. E., Chen, Guo-Bo, Lee, Sang Hong, Wray, Naomi R., Goddard, Michael E. and Yang, Jian (2014). Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples. PLoS Genetics, 10 (4) e1004269, e1004269.1-e1004269.10. doi: 10.1371/journal.pgen.1004269

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

2014

Journal Article

Two opposing effects of sulfate reduction on carbonate precipitation in normal marine, hypersaline, and alkaline environments Comment

Gallagher, Kimberley L., Dupraz, Christophe and Visscher, Pieter T. (2014). Two opposing effects of sulfate reduction on carbonate precipitation in normal marine, hypersaline, and alkaline environments Comment. Geology, 42 (1), E313-E314. doi: 10.1130/G34639C.1

Two opposing effects of sulfate reduction on carbonate precipitation in normal marine, hypersaline, and alkaline environments Comment

2014

Journal Article

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Catts, Stanley V., Gratten, Jacob, Lee, S. Hong, Wray, Naomi R., Visscher, Peter M., Mowry, Bryan J., Nertney, Deborah A., Psychosis Endophenotypes International Consortium and Wellcome Trust Case-Control Consortium 2 (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511 (7510), 421-427. doi: 10.1038/nature13595

Biological insights from 108 schizophrenia-associated genetic loci

2014

Journal Article

Molecular genetic contributions to socioeconomic status and intelligence

Marioni, Riccardo E., Davies, Gail, Hayward, Caroline, Liewald, Dave, Kerr, Shona M., Campbell, Archie, Luciano, Michelle, Smith, Blair H., Padmanabhan, Sandosh, Hocking, Lynne J., Hastie, Nicholas D., Wright, Alan F., Porteous, David J., Visscher, Peter M. and Deary, Ian J. (2014). Molecular genetic contributions to socioeconomic status and intelligence. Intelligence (Kidlington), 44 (1), 26-32. doi: 10.1016/j.intell.2014.02.006

Molecular genetic contributions to socioeconomic status and intelligence

2014

Journal Article

Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index

Hoggart, C. J., Venturini, G., Mangino, M., Gomez, F., Ascari, G., Zhao, J.H., Teumer, A., Winkler, T. W., Tsernikova, N., Luan, J., Mihailov, E., Ehret, G. B., Zhang, W., Lamparter, D., Esko, T., Mace, A., Rueger, S., Bochud, P.-Y., Barcella, M., Dauvilliers, Y., Benyamin, B., Evans, D. M., Hayward, C., Lopez, M. F., Franke, L., Russo, A., Heid, I. M., Salvi, E., Vendantam, S. ... Kutalik Z. (2014). Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index. PLoS Genetics, 10 (7) e1004508, 1-12. doi: 10.1371/journal.pgen.1004508

Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index

2014

Journal Article

Large-scale genomics unveils the genetic architecture of psychiatric disorders

Gratten, Jacob, Wray, Naomi R., Keller, Matthew C. and Visscher, Peter M. (2014). Large-scale genomics unveils the genetic architecture of psychiatric disorders. Nature Neuroscience, 17 (6), 782-790. doi: 10.1038/nn.3708

Large-scale genomics unveils the genetic architecture of psychiatric disorders

2013

Journal Article

Schizophrenia genetic variants are not associated with intelligence

Terwisscha van Scheltinga, A. F., Bakker, S. C., Van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Cahn, W., Ripke, S., Ophoff, R. A., Kahn, R. S., Psychiatric Genomic-Wide Association Study (GWAS) Consortium, Visscher, P. M., Mowry, B. J., Brown, M. A., McGrath, J. J. and McLean, Duncan E. (2013). Schizophrenia genetic variants are not associated with intelligence. Psychological Medicine, 43 (12), 2563-2570. doi: 10.1017/S0033291713000196

Schizophrenia genetic variants are not associated with intelligence

2013

Journal Article

Author reply to A commentary on Pitfalls of predicting complex traits from SNPs

Wray, Naomi R., Yang, Jian, Hayes, Ben J., Price, Alkes L., Goddard, Michael E. and Visscher, Peter M. (2013). Author reply to A commentary on Pitfalls of predicting complex traits from SNPs. Nature Reviews Genetics, 14 (12), 894-894. doi: 10.1038/nrg3457-c2

Author reply to A commentary on Pitfalls of predicting complex traits from SNPs

2013

Journal Article

A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability

Derks, Eske M., Ayub, Muhammad, Chambert, Kimberly, Del Favero, Jurgen, Johnstone, Mandy, Macgregor, Stuart, Maclean, Alan, McKechanie, Andrew G., McRae, Allan F., Moran, Jennifer L., Pickard, Benjamin S., Purcell, Shaun, Sklar, Pamela, St Clair, David M., Wray, Naomi R., Visscher, Peter M. and Blackwood, Douglas H. R. (2013). A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 162 (8), 847-854. doi: 10.1002/ajmg.b.32189

A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability

2013

Journal Article

Estimation and partition of heritability in human populations using whole-genome analysis methods

Vinkhuyzen, Anna A.E., Wray, Naomi R., Yang, Jiang, Goddard, Michael E. and Visscher, Peter M. (2013). Estimation and partition of heritability in human populations using whole-genome analysis methods. Annual Review of Genetics, Review in Advance: 47 (5), 93-113. doi: 10.1146/annurev-genet-111212-133258

Estimation and partition of heritability in human populations using whole-genome analysis methods

2013

Journal Article

Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs

Hemani, Gibran, Yang, Jian, Vinkhuyzen, Anna, Powell, Joseph E., Willemsen, Gonneke, Hottenga, Jouke-Jan, Abdellaoui, Abdel, Mangino, Massimo, Valdes, Ana M., Medland, Sarah E., Madden, Pamela A., Heath, Andrew C., Henders, Anjali K., Nyholt, Dale R., de Geus, Eco J. C., Magnusson, Patrik K. E., Ingelsson, Erik, Montgomery, Grant W., Spector, Timothy D., Boomsma, Dorret I., Pedersen, Nancy L., Martin, Nicholas G. and Visscher, Peter M. (2013). Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs. American Journal of Human Genetics, 93 (5), 865-875. doi: 10.1016/j.ajhg.2013.10.005

Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs

2013

Journal Article

Stromatolitic knobs in Storr's Lake (San Salvador, Bahamas): a model system for formation and alteration of laminae

Dupraz, C., Fowler, A., Tobias, C. and Visscher, P. T. (2013). Stromatolitic knobs in Storr's Lake (San Salvador, Bahamas): a model system for formation and alteration of laminae. Geobiology, 11 (6), 527-548. doi: 10.1111/gbi.12063

Stromatolitic knobs in Storr's Lake (San Salvador, Bahamas): a model system for formation and alteration of laminae

2013

Journal Article

Response to 'Predicting the diagnosis of autism spectrum disorder using gene pathway analysis'

Robinson, E. B., Howrigan, D., Yang, J., Ripke, S., Anttila, V., Duncan, L. E., Jostins, L., Barrett, J. C., Medland, S. E., Macarthur, D. G., Breen, G., O'Donovan, M. C., Wray, N. R., Devlin, B., Daly, M. J., Visscher, P. M., Sullivan, P. F. and Neale, B. M. (2013). Response to 'Predicting the diagnosis of autism spectrum disorder using gene pathway analysis'. Molecular Psychiatry, 19 (8), 859-861. doi: 10.1038/mp.2013.125

Response to 'Predicting the diagnosis of autism spectrum disorder using gene pathway analysis'

2013

Journal Article

A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk

Revez, J. A., Bain, L., Chapman, B., Powell, J. E., Jansen, R., Duffy, D. L., Tung, J. Y., AAGC Collaborators, Penninx, B. W., Visscher, P. M., De Geus, E. J. C., Boomsma, D. I., Hinds, D. A., Martin, N. G., Montgomery, G. W., Ferreira, M. A. R., Danoy, Patrick and Brown, Matthew A. (2013). A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk. Genes and Immunity, 14 (7), 441-446. doi: 10.1038/gene.2013.38

A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk

2013

Journal Article

Systematic identification of trans eQTLs as putative drivers of known disease associations

Westra, Harm-Jan, Peters, Marjolein J., Esko, Tonu, Yaghootkar, Hanieh, Schurmann, Claudia, Kettunen, Johannes, Christiansen, Mark W., Fairfax, Benjamin P., Schramm, Katharina, Powell, Joseph E., Zhernakova, Alexandra, Zhernakova, Daria V., Veldink, Jan H., Van den Berg, Leonard H., Karjalainen, Juha, Withoff, Sebo, Uitterlinden, Andre G., Hofman, Albert, Rivadeneira, Fernando, Hoen, Peter A. C't, Reinmaa, Eva, Fischer, Krista, Nelis, Mari, Milani, Lili, Melzer, David, Ferrucci, Luigi, Singleton, Andrew B., Hernandez, Dena G., Nalls, Michael A. ... Franke, Lude (2013). Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genetics, 45 (10), 1238-U195. doi: 10.1038/ng.2756

Systematic identification of trans eQTLs as putative drivers of known disease associations

2013

Journal Article

What if we had whole-genome sequence data for millions of individuals?

Visscher, Peter and Gibson, Greg (2013). What if we had whole-genome sequence data for millions of individuals?. Genome Medicine, 5 (80) 80, 80.1-80.3. doi: 10.1186/gm484

What if we had whole-genome sequence data for millions of individuals?