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2014

Journal Article

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

Bracken, Cameron P., Li, Xiaochun, Wright, Joesphine A., Lawrence, David, Pillman, Katherine A., Salmanidis, Markia, Anderson, Matthew A., Dredge, B. Kate, Gregory, Philip A., Tsykin, Anna, Neilsen, Corine, Thomson, Daniel W., Bert, Andrew G., Leerberg, Joanne M., Yap, Alpha S., Jensen, Kirk B., Khew-Goodall, Yeesim and Goodall, Gregory J. (2014). Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion. The EMBO Journal, 33 (18), 2040-2056. doi: 10.15252/embj.201488641

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

2014

Journal Article

Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis

Chaudhary, Natasha, Gomez, Guillermo A., Howes, Mark T., Lo, Harriet P., McMahon, Kerrie-Ann, Rae, James A., Schieber, Nicole L., Hill, Michelle M., Gaus, Katharina, Yap, Alpha S. and Parton, Robert G. (2014). Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis. PLoS Biology, 12 (4) e1001832, e1001832.1-e1001832.20. doi: 10.1371/journal.pbio.1001832

Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis

2014

Journal Article

alpha-Catenin cytomechanics: role in cadherin-dependent adhesion and mechanotransduction

Barry, Adrienne K., Tabdili, Hamid, Muhamed, Ismaeel, Wu, Jun, Shashikanth, Nitesh, Gomez, Guillermo A., Yap, Alpha S., Gottardi, Cara J., de Rooij, Johan, Wang, Ning and Leckband, Deborah E. (2014). alpha-Catenin cytomechanics: role in cadherin-dependent adhesion and mechanotransduction. Journal of Cell Science, Advance Online Article (8), 1-42. doi: 10.1242/jcs.139014

alpha-Catenin cytomechanics: role in cadherin-dependent adhesion and mechanotransduction

2014

Journal Article

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

Wu, Selwin K., Gomez, Guillermo A., Michael, Magdalene, Verma, Suzie, Cox, Hayley L., Lefevre, James G., Parton, Robert G., Hamilton, Nicholas A., Neufeld, Zoltan and Yap, Alpha S. (2014). Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia. Nature Cell Biology, 16 (2), 167-178. doi: 10.1038/ncb2900

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

2014

Journal Article

The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells

Cameron, Andrew R., Frith, Jessica E., Gomez, Guillermo A., Yap, Alpha S and Cooper-White, Justin J. (2014). The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells. Biomaterials, 35 (6), 1857-1868. doi: 10.1016/j.biomaterials.2013.11.023

The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells

2014

Journal Article

Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens

Han, Siew Ping, Gambin, Yann, Gomez, Guillermo A., Verma, Suzie, Giles, Nichole, Michael, Magdalene, Wu, Selwin K., Guo, Zhong, Johnston, Wayne, Sierecki, Emma, Parton, Robert G., Alexandrov, Kirill and Yap, Alpha S. (2014). Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens. Journal of Biological Chemistry, 289 (11) 790, 7764-7775. doi: 10.1074/jbc.M113.544478

Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens

2014

Journal Article

RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin

Truffi, Marta, Dubreuil, Veronique, Liang, Xuan, Vacaresse, Nathalie, Nigon, Fabienne, Han, Siew Ping, Yap, Alpha S., Gomez, Guillermo A. and Sap, Jan (2014). RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin. Journal of Cell Science, 127 (11), 2420-2432. doi: 10.1242/jcs.134379

RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin

2014

Journal Article

Endothelial cell-cell adhesion during zebrafish vascular development

Lagendijk, Anne Karine, Yap, Alpha S. and Hogan, Benjamin M. (2014). Endothelial cell-cell adhesion during zebrafish vascular development. Cell Adhesion and Migration, 8 (2), 136-145. doi: 10.4161/cam.28229

Endothelial cell-cell adhesion during zebrafish vascular development

2013

Journal Article

Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions

Wu, Selwin Kaixiang and Yap, Alpha S. (2013). Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions. Cell Communication and Adhesion, 20 (6), 201-212. doi: 10.3109/15419061.2013.856889

Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions

2013

Journal Article

On giant's shoulders: an interview with Masatoshi Takeichi (RIKEN Centre for Developmental Biology, Kobe)

Yap, Alpha S. and Takeichi, Masatoshi (2013). On giant's shoulders: an interview with Masatoshi Takeichi (RIKEN Centre for Developmental Biology, Kobe). Cell Communication and Adhesion, Early Online (6), 1-3. doi: 10.3109/15419061.2013.854333

On giant's shoulders: an interview with Masatoshi Takeichi (RIKEN Centre for Developmental Biology, Kobe)

2013

Journal Article

E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens

Priya, Rashmi, Yap, Alpha S. and Gomez, Guillermo A. (2013). E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens. Differentiation, 86 (3), 133-140. doi: 10.1016/j.diff.2013.01.002

E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens

2013

Journal Article

A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton

Budnar S. and Yap A.S. (2013). A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton. F1000 Prime Reports, 5 (35) 35, 35.1-35.6. doi: 10.12703/P5-35

A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton

2013

Journal Article

Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions

Leerberg, Joanne M. and Yap, Alpha S.K. (2013). Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions. Protoplasma, 250 (4), 817-829. doi: 10.1007/s00709-012-0475-6

Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions

2013

Journal Article

Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries

Bulgakova, Natalia A., Grigoriev, Ilya, Yap, Alpha S., Akhmanova, Anna and Brown, Nicholas H. (2013). Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries. Journal of Cell Biology, 201 (6), 887-901. doi: 10.1083/jcb.201211159

Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries

2013

Journal Article

The regulation and functional impact of actin assembly at cadherin cell-cell adhesions

Magdalene, Michael and Yap, Alpha S. (2013). The regulation and functional impact of actin assembly at cadherin cell-cell adhesions. Seminars in Cell & Developmental Biology, 24 (4), 298-307. doi: 10.1016/j.semcdb.2012.12.004

The regulation and functional impact of actin assembly at cadherin cell-cell adhesions

2013

Journal Article

An alpha-catenin deja vu

Han, Siew-Ping and Yap, Alpha S. (2013). An alpha-catenin deja vu. Nature Cell Biology, 15 (3), 238-239. doi: 10.1038/ncb2700

An alpha-catenin deja vu

2013

Journal Article

Cadherin junctions and their cytoskeleton(s)

Brieher, William M. and Yap, Alpha S. (2013). Cadherin junctions and their cytoskeleton(s). Current Opinion in Cell Biology, 25 (1), 39-46. doi: 10.1016/j.ceb.2012.10.010

Cadherin junctions and their cytoskeleton(s)

2012

Journal Article

A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

Verma, Suzie, Han, Siew Ping, Michael, Magdalene, Gomez, Guillermo, Yang, Zhe, Teasdale, Rohan D., Ratheesh, Aparna, Kovacs, Eva M., Ali, Radiya G. and Yap, Alpha S.K. (2012). A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens. Molecular Biology of The Cell, 23 (23), 4601-4610. doi: 10.1091/mbc.E12-08-0574

A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

2012

Journal Article

A bigger picture: classical cadherins and the dynamic actin cytoskeleton

Ratheesh, Aparna and Yap, Alpha S. (2012). A bigger picture: classical cadherins and the dynamic actin cytoskeleton. Nature Reviews Molecular Cell Biology, 13 (10), 673-679. doi: 10.1038/nrm3431

A bigger picture: classical cadherins and the dynamic actin cytoskeleton

2012

Journal Article

The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI

Mangold, Sabine, Norwood, Suzanne J., Yap, Alpha S and Collins, Brett M. (2012). The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI. BioArchitecture, 2 (5), 185-188. doi: 10.4161/bioa.22082

The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI