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2020

Journal Article

Symmetry breaking and epithelial cell extrusion

Nanavati, Bageshri Naimish, Yap, Alpha S. and Teo, Jessica L. (2020). Symmetry breaking and epithelial cell extrusion. Cells, 9 (6) 1403, 1416. doi: 10.3390/cells9061416

Symmetry breaking and epithelial cell extrusion

2020

Journal Article

Endocytosis, cadherins and tissue dynamics

Katsuno‐Kambe, Hiroko and Yap, Alpha S. (2020). Endocytosis, cadherins and tissue dynamics. Traffic, 21 (3) tra.12721, 268-273. doi: 10.1111/tra.12721

Endocytosis, cadherins and tissue dynamics

2020

Journal Article

Caveolae control contractile tension for epithelia to eliminate tumor cells

Teo, Jessica L., Gomez, Guillermo A., Weeratunga, Saroja, Davies, Elizabeth M., Noordstra, Ivar, Budnar, Srikanth, Katsuno-Kambe, Hiroko, McGrath, Meagan J., Verma, Suzie, Tomatis, Vanesa, Acharya, Bipul R., Balasubramaniam, Lakshmi, Templin, Rachel M., McMahon, Kerrie-Ann, Lee, Yoke Seng, Ju, Robert J., Stebhens, Samantha J., Ladoux, Benoit, Mitchell, Christina A., Collins, Brett M., Parton, Robert G. and Yap, Alpha S. (2020). Caveolae control contractile tension for epithelia to eliminate tumor cells. Developmental Cell, 54 (1), 75-91.e7. doi: 10.1016/j.devcel.2020.05.002

Caveolae control contractile tension for epithelia to eliminate tumor cells

2019

Journal Article

Five piconewtons: the difference between osteogenic and adipogenic fate choice in human mesenchymal stem cells

Han, Pingping, Frith, Jessica E., Gomez, Guillermo A., Yap, Alpha S., O'Neill, Geraldine M. and Cooper-White, Justin J. (2019). Five piconewtons: the difference between osteogenic and adipogenic fate choice in human mesenchymal stem cells. ACS Nano, 13 (10) acsnano.9b03914, 11129-11143. doi: 10.1021/acsnano.9b03914

Five piconewtons: the difference between osteogenic and adipogenic fate choice in human mesenchymal stem cells

2019

Journal Article

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

McMahon, Kerrie-Ann, Wu, Yeping, Gambin, Yann, Sierecki, Emma, Tillu, Vikas A., Hall, Thomas, Martel, Nick, Okano, Satomi, Moradi, Shayli Varasteh, Ruelcke, Jayde E., Ferguson, Charles, Yap, Alpha S., Alexandrov, Kirill, Hill, Michelle M. and Parton, Robert G. (2019). Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nature Communications, 10 (1) 3279, 3279. doi: 10.1038/s41467-019-11111-1

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

2019

Journal Article

The membrane environment of cadherin adhesion receptors: a working hypothesis

Teo, Jessica L., Parton, Robert G. and Yap, Alpha S. (2019). The membrane environment of cadherin adhesion receptors: a working hypothesis. Biochemical Society Transactions, 47 (4), BST20180012-995. doi: 10.1042/bst20180012

The membrane environment of cadherin adhesion receptors: a working hypothesis

2019

Journal Article

Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics

Budnar, Srikanth, Husain, Kabir B., Gomez, Guillermo A., Naghibosadat, Maedeh, Varma, Amrita, Verma, Suzie, Hamilton, Nicholas A., Morris, Richard G. and Yap, Alpha S. (2019). Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics. Developmental Cell, 49 (6), 894-906.e1-e12. doi: 10.1016/j.devcel.2019.04.031

Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics

2019

Journal Article

Erratum to: Wetting by living tissues (Nature Physics, (2018), 10.1038/s41567-018-0316-4)

Morris, Richard G. and Yap, Alpha S. (2019). Erratum to: Wetting by living tissues (Nature Physics, (2018), 10.1038/s41567-018-0316-4). Nature Physics, 15 (1), 103-103. doi: 10.1038/s41567-018-0337-z

Erratum to: Wetting by living tissues (Nature Physics, (2018), 10.1038/s41567-018-0316-4)

2018

Journal Article

A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress

Acharya, Bipul R., Nestor-Bergmann, Alexander, Liang, Xuan, Gupta, Shafali, Duszyc, Kinga, Gauquelin, Estelle, Gomez, Guillermo A., Budnar, Srikanth, Marcq, Philippe, Jensen, Oliver E., Bryant, Zev and Yap, Alpha S. (2018). A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress. Developmental Cell, 47 (4), 439-452. doi: 10.1016/j.devcel.2018.09.016

A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress

2018

Journal Article

Mechanosensing and mechanotransduction at cell-cell junctions

Yap, Alpha S., Duszyc, Kinga and Viasnoff, Virgile (2018). Mechanosensing and mechanotransduction at cell-cell junctions. Cold Spring Harbor Perspectives in Biology, 10 (8) a028761, a028761. doi: 10.1101/cshperspect.a028761

Mechanosensing and mechanotransduction at cell-cell junctions

2018

Journal Article

Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets

Gao, Xumei, Acharya, Bipul R., Engl, Wilfried Claude Otto, De Mets, Richard, Thiery, Jean Paul, Yap, Alpha S. and Viasnoff, Virgile (2018). Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets. APL Bioengineering, 2 (2) 026111, 026111. doi: 10.1063/1.5025216

Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets

2018

Journal Article

Tensile forces and mechanotransduction at cell-cell junctions

Charras, Guillaume and Yap, Alpha S (2018). Tensile forces and mechanotransduction at cell-cell junctions. Current Biology, 28 (8), R445-R457. doi: 10.1016/j.cub.2018.02.003

Tensile forces and mechanotransduction at cell-cell junctions

2018

Journal Article

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

Boucher, Dave, Monteleone, Mercedes, Coll, Rebecca C., Chen, Kaiwen W., Ross, Connie M., Teo, Jessica L., Gomez, Guillermo A., Holley, Caroline L., Bierschenk, Damien, Stacey, Katryn J., Yap, Alpha S., Bezbradica, Jelena S. and Schroder, Kate (2018). Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity. The Journal of Experimental Medicine, 215 (3), 827-840. doi: 10.1084/jem.20172222

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

2018

Journal Article

Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation

Liang, Xuan, Kiru, Sajini, Gomez, Guillermo A. and Yap, Alpha S. (2018). Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation. Cytoskeleton, 75 (2), 61-69. doi: 10.1002/cm.21420

Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation

2018

Journal Article

Role of contact inhibition of locomotion and junctional mechanics in epithelial collective responses to injury

Coburn, Luke, Lopez, Hender, Schouwenaar, Irin-Maya, Yap, Alpha S., Lobaskin, Vladimir and Gomez, Guillermo A. (2018). Role of contact inhibition of locomotion and junctional mechanics in epithelial collective responses to injury. Physical Biology, 15 (2) 024001, 024001. doi: 10.1088/1478-3975/aa976b

Role of contact inhibition of locomotion and junctional mechanics in epithelial collective responses to injury

2018

Journal Article

Notching a new pathway in vascular flow sensing

Lagendijk, Anne K., Yap, Alpha S. and Hogan, Benjamin M. (2018). Notching a new pathway in vascular flow sensing. Trends in Cell Biology, 28 (3), 173-175. doi: 10.1016/j.tcb.2017.12.003

Notching a new pathway in vascular flow sensing

2018

Journal Article

Wetting by living tissues

Morris, Richard G. and Yap, Alpha S. (2018). Wetting by living tissues. Nature Physics, 15 (1), 6-7. doi: 10.1038/s41567-018-0316-4

Wetting by living tissues

2017

Journal Article

Author Correction: tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Liang, Xuan, Budnar, Srikanth, Gupta, Shafali, Verma, Suzie, Han, Siew-Ping, Hill, Michelle M., Daly, Roger J, Parton, Robert G., Hamilton, Nicholas A., Gomez, Guillermo A. and Yap, Alpha S. (2017). Author Correction: tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nature Communications, 8 (2021) 2021, 2021. doi: 10.1038/s41467-017-02131-w

Author Correction: tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

2017

Journal Article

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Liang, Xuan, Budnar, Srikanth, Gupta, Shafali, Verma, Suzie, Han, Siew-Ping, Hill, Michelle M., Daly, Roger J., Parton, Robert G., Hamilton, Nicholas A., Gomez, Guillermo A. and Yap, Alpha S. (2017). Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nature Communications, 8 (1) 790, 790. doi: 10.1038/s41467-017-00797-w

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

2017

Journal Article

Versatile Scaffold: Extrajunctional Roles for α-Catenin

Budnar, Srikanth and Yap, Alpha S. (2017). Versatile Scaffold: Extrajunctional Roles for α-Catenin. Developmental Cell, 43 (4), 381-382. doi: 10.1016/j.devcel.2017.11.004

Versatile Scaffold: Extrajunctional Roles for α-Catenin