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2022

Journal Article

Correction: Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction

Cavanaugh, Kate E., Staddon, Michael F., Chmiel, Theresa A., Harmon, Robert, Budnar, Srikanth, Yap, Alpha S., Banerjee, Shiladitya and Gardel, Margaret L. (2022). Correction: Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction. Current Biology, 32 (21) 4779, 4779-4779. doi: 10.1016/j.cub.2022.10.011

Correction: Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction

2022

Journal Article

Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction

Cavanaugh, Kate E., Staddon, Michael F., Chmiel, Theresa A., Harmon, Robert, Budnar, Srikanth, Yap, Alpha S., Banerjee, Shiladitya and Gardel, Margaret L. (2022). Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction. Current Biology, 32 (9), 1986-2000.e5. doi: 10.1016/j.cub.2022.03.024

Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction

2022

Journal Article

Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death

Bonfim-Melo, Alexis, Noordstra, Ivar, Gupta, Shafali, Chan, Amy H., Jones, Mathew J.K., Schroder, Kate and Yap, Alpha S. (2022). Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death. Cell Reports, 38 (5) 110316, 110316. doi: 10.1016/j.celrep.2022.110316

Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death

2022

Journal Article

Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis

Bonfim-Melo, Alexis, Duszyc, Kinga, Gomez, Guillermo A. and Yap, Alpha S. (2022). Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis. The European Physical Journal E, 45 (1) 9, 9. doi: 10.1140/epje/s10189-022-00163-9

Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis

2021

Journal Article

Live imaging of apoptotic extrusion and quantification of apical extrusion in epithelial cells

Duszyc, Kinga, Noordstra, Ivar, Yap, Alpha S and Gomez, Guillermo A (2021). Live imaging of apoptotic extrusion and quantification of apical extrusion in epithelial cells. Bio-protocol, 11 (22) e4232, e4232. doi: 10.21769/BioProtoc.4232

Live imaging of apoptotic extrusion and quantification of apical extrusion in epithelial cells

2021

Journal Article

Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

Katsuno-Kambe, Hiroko, Teo, Jessica L., Ju, Robert J., Hudson, James, Stehbens, Samantha J. and Yap, Alpha S. (2021). Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation. eLife, 10 e67915. doi: 10.7554/elife.67915

Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

2021

Journal Article

Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers

Gupta, Shafali, Duszyc, Kinga, Verma, Suzie, Budnar, Srikanth, Liang, Xuan, Gomez, Guillermo A., Marcq, Philippe, Noordstra, Ivar and Yap, Alpha S. (2021). Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers. Journal of Cell Science, 134 (17) jcs258767, 1-13. doi: 10.1242/jcs.258767

Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers

2021

Journal Article

Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

McMahon, Kerrie-Ann, Stroud, David A., Gambin, Yann, Tillu, Vikas, Bastiani, Michele, Sierecki, Emma, Polinkovsky, Mark E., Hall, Thomas E., Gomez, Guillermo A., Wu, Yeping, Parat, Marie-Odile, Martel, Nick, Lo, Harriet P., Khanna, Kum Kum, Alexandrov, Kirill, Daly, Roger, Yap, Alpha, Ryan, Michael T. and Parton, Robert G. (2021). Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response. eLife, 10 e61407, 1-35. doi: 10.7554/elife.61407

Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

2021

Journal Article

For whom the cell tolls

Noordstra, Ivar and Yap, Alpha S. (2021). For whom the cell tolls. Developmental Cell, 56 (11), 1555-1557. doi: 10.1016/j.devcel.2021.05.013

For whom the cell tolls

2021

Journal Article

Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers

Balasubramaniam, Lakshmi, Doostmohammadi, Amin, Saw, Thuan Beng, Narayana, Gautham Hari Narayana Sankara, Mueller, Romain, Dang, Tien, Thomas, Minnah, Gupta, Shafali, Sonam, Surabhi, Yap, Alpha S., Toyama, Yusuke, Mège, René-Marc, Yeomans, Julia M. and Ladoux, Benoît (2021). Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers. Nature Materials, 20 (8), 1156-1166. doi: 10.1038/s41563-021-00919-2

Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers

2021

Journal Article

Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion

Duszyc, Kinga, Gomez, Guillermo A., Lagendijk, Anne K., Yau, Mei-Kwan, Nanavati, Bageshri Naimish, Gliddon, Briony L., Hall, Thomas E., Verma, Suzie, Hogan, Benjamin M., Pitson, Stuart M., Fairlie, David P., Parton, Robert G. and Yap, Alpha S. (2021). Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion. Current Biology, 31 (6), 1326-1336.e5. doi: 10.1016/j.cub.2021.01.003

Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion

2021

Journal Article

Caveolin-1 influences epithelial collective cell migration via FMNL2 formin

Katsuno-Kambe, Hiroko, Parton, Robert G, Yap, Alpha S and Teo, Jessica L (2021). Caveolin-1 influences epithelial collective cell migration via FMNL2 formin. Biology of the Cell, 113 (2), 107-117. doi: 10.1111/boc.202000116

Caveolin-1 influences epithelial collective cell migration via FMNL2 formin

2021

Journal Article

Author Correction: Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers (Nature Materials, (2021), 10.1038/s41563-021-00919-2)

Balasubramaniam, Lakshmi, Doostmohammadi, Amin, Saw, Thuan Beng, Narayana, Gautham Hari Narayana Sankara, Mueller, Romain, Dang, Tien, Thomas, Minnah, Gupta, Shafali, Sonam, Surabhi, Yap, Alpha S., Toyama, Yusuke, Mège, René-Marc, Yeomans, Julia M. and Ladoux, Benoît (2021). Author Correction: Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers (Nature Materials, (2021), 10.1038/s41563-021-00919-2). Nature Materials, 20 (8), 1167-1167. doi: 10.1038/s41563-021-00974-9

Author Correction: Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers (Nature Materials, (2021), 10.1038/s41563-021-00919-2)

2020

Journal Article

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies

Gormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies

2020

Journal Article

Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion

Teo, Jessica L, Tomatis, Vanesa M, Coburn, Luke, Lagendijk, Anne K, Schouwenaar, Irin-Maya, Budnar, Srikanth, Hall, Thomas E, Verma, Suzie, McLachlan, Robert W, Hogan, Benjamin M, Parton, Robert G, Yap, Alpha S and Gomez, Guillermo A (2020). Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion. Molecular Biology of the Cell, 31 (23), 2495-2629. doi: 10.1091/mbc.E20-01-0084

Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion

2020

Journal Article

Hands and feet: closer than you think in epithelial migration

Gupta, Shafali and Yap, Alpha S. (2020). Hands and feet: closer than you think in epithelial migration. Journal of Cell Biology, 219 (10) e202008069. doi: 10.1083/jcb.202008069

Hands and feet: closer than you think in epithelial migration

2020

Journal Article

A biologist’s guide to traction force microscopy using polydimethylsiloxane substrate for two-dimensional cell cultures

Teo, Jessica L., Lim, Chwee Teck, Yap, Alpha S. and Saw, Thuan Beng (2020). A biologist’s guide to traction force microscopy using polydimethylsiloxane substrate for two-dimensional cell cultures. STAR Protocols, 1 (2) 100098, 100098. doi: 10.1016/j.xpro.2020.100098

A biologist’s guide to traction force microscopy using polydimethylsiloxane substrate for two-dimensional cell cultures

2020

Journal Article

Anillin: the first proofreading-like scaffold?

Morris, Richard G., Husain, Kabir B., Budnar, Srikanth and Yap, Alpha S. (2020). Anillin: the first proofreading-like scaffold?. BioEssays, 42 (10) 2000055, e2000055. doi: 10.1002/bies.202000055

Anillin: the first proofreading-like scaffold?

2020

Journal Article

Forces, growth and form: an editorial introduction

Yap, Alpha S. (2020). Forces, growth and form: an editorial introduction. Molecular Biology of the Cell, 31 (16), 1651-1653. doi: 10.1091/mbc.E20-06-0414

Forces, growth and form: an editorial introduction

2020

Journal Article

Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell–matrix adhesion

Wee, Kenneth, Hediyeh-Zadeh, Soroor, Duszyc, Kinga, Verma, Suzie, Nanavati, Bageshri N., Khare, Satyajeet, Varma, Amrita, Daly, Roger J., Yap, Alpha S., Davis, Melissa J. and Budnar, Srikanth (2020). Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell–matrix adhesion. Journal of Cell Science, 133 (13) jcs235622, jcs235622. doi: 10.1242/jcs.235622

Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell–matrix adhesion