2015 Journal Article Towards a dynamic understanding of cadherin-based mechanobiologyHoffman, Brenton D. and Yap, Alpha S. (2015). Towards a dynamic understanding of cadherin-based mechanobiology. Trends in Cell Biology, 25 (12), 803-814. doi: 10.1016/j.tcb.2015.09.008 |
2015 Journal Article Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomesMarta Kubala, Norwood, Suzanne, Gomez, Guillermo, Jones, Alun, Johnston, Wayne A., Yap, Alpha S.K., Mureev, Sergey and Alexandrov, Kirill (2015). Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes. Biochemical and Biophysical Research Communications, 468 (4), 580-586. doi: 10.1016/j.bbrc.2015.10.148 |
2015 Journal Article Adherens Junctions Revisualized: Organizing Cadherins as NanoassembliesYap, Alpha S., Gomez, Guillermo A. and Parton, Robert G. (2015). Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies. Developmental Cell, 35 (1) 3402, 12-20. doi: 10.1016/j.devcel.2015.09.012 |
2015 Journal Article Modelling wound closure in an epithelial cell sheet using the cellular Potts modelNoppe, Adrian R., Roberts, Anthony P., Yap, Alpha S., Gomez, Guillermo A. and Neufeld, Zoltan (2015). Modelling wound closure in an epithelial cell sheet using the cellular Potts model. Integrative Biology (United Kingdom), 7 (10), 1253-1264. doi: 10.1039/c5ib00053j |
2015 Journal Article Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctionsPriya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Verma, Suzie, Cox, Hayley L., Hamilton, Nicholas A. and Yap, Alpha S. (2015). Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nature Cell Biology, 17 (10), 1282-1293. doi: 10.1038/ncb3239 |
2015 Journal Article Making a choice: how cadherin switching controls cell migrationPriya, Rashmi and Yap, Alpha S. (2015). Making a choice: how cadherin switching controls cell migration. Developmental Cell, 34 (4) 3369, 383-384. doi: 10.1016/j.devcel.2015.08.002 |
2015 Journal Article Seeing and believing: recent advances in imaging cell-cell interactionsYap, Alpha S., Michael, Magdalene and Parton, Robert G. (2015). Seeing and believing: recent advances in imaging cell-cell interactions. F1000Research, 4 (F1000 Faculty Rev) 273, 273.1-273.8. doi: 10.12688/f1000research.6435.1 |
2015 Journal Article Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organizationGreenlees, Rebecca, Mihelec, Marija, Yousoof, Saira, Speidel, Daniel, Wu, Selwin K., Rinkwitz, Silke, Prokudin, Ivan, Perveen, Rahat, Cheng, Anson, Ma, Alan, Nash, Benjamin, Gillespie, Rachel, Loebel, David A. F., Clayton-Smith, Jill, Lloyd, I. Christopher, Grigg, John R., Tam, Patrick P. L., Yap, Alpha S., Becker, Thomas S., Black, Graeme C. M., Semina, Elena and Jamieson, Robyn V. (2015). Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization. Human Molecular Genetics, 24 (20), 5789-5804. doi: 10.1093/hmg/ddv298 |
2015 Journal Article E-cadherin junctions as active mechanical integrators in tissue dynamicsLecuit, Thomas and Yap, Alpha S. (2015). E-cadherin junctions as active mechanical integrators in tissue dynamics. Nature Cell Biology, 17 (5), 533-539. doi: 10.1038/ncb3136 |
2015 Journal Article An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctionsGomez, Guillermo A., McLachlan, Robert W., Wu, Selwin K., Caldwell, Benjamin J., Moussa, Elliott, Verma, Suzie, Bastiani, Michele, Priya, Rashmi, Parton, Robert G., Gaus, Katharina, Sap, Jan and Yap, Alpha S. (2015). An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions. Molecular Biology of the Cell, 26 (7), 1249-1262. doi: 10.1091/mbc.E14-07-1223 |
2015 Journal Article Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafishKoltowska, Katarzyna, Lagendijk, Anne K., Pichol-Thievend, Cathy, Fischer, Johanna C., Francois, Mathias, Ober, Elke A., Yap, Alpha S. and Hogan, Benjamin M. (2015). Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafish. Cell Reports, 13 (9), 1828-1841. doi: 10.1016/j.celrep.2015.10.055 |
2015 Journal Article Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle dockingPapadopulos, Andreas, Gomez, Guillermo A., Martin, Sally, Jackson, Jade, Gormal, Rachel S., Keating, Damien J., Yap, Alpha S. and Meunier, Frederic A. (2015). Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking. Nature Communications, 6 (6297) 6297, 1-11. doi: 10.1038/ncomms7297 |
2015 Journal Article Active contractility at E-cadherin junctions and its implications for cell extrusion in cancerWu, Selwin K., Lagendijk, Anne K., Hogan, Benjamin M., Gomez, Guillermo A. and Yap, Alpha S. (2015). Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer. Cell Cycle, 14 (3), 315-322. doi: 10.4161/15384101.2014.989127 |
2015 Journal Article Current perspectives on cadherin-cytoskeleton interactions and dynamicsLiang, Xuan, Gomez, Guillermo A. and Yap, Alpha S. (2015). Current perspectives on cadherin-cytoskeleton interactions and dynamics. Cell Health and Cytoskeleton, 7, 11-24. doi: 10.2147/CHC.S76107 |
2015 Journal Article PrefaceYap, Alpha S. (2015). Preface. Cellular Adhesion in Development and Disease, 112, XV-XVII. doi: 10.1016/S0070-2153(15)00024-1 |
2014 Journal Article Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctionsMoore, Thomas, Wu, Selwin, Michael, Magdalene, Yap, Alpha S.K., Gomez, Guillermo A. and Neufeld, Zoltan (2014). Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctions. Biophysical Journal, 107 (11), 2652-2661. doi: 10.1016/j.bpj.2014.10.045 |
2014 Journal Article Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherensCaldwell, Benjamin J., Lucas, Christine, Kee, Anthony J., Gaus, Katharina, Gunning, Peter W., Hardeman, Edna C., Yap, Alpha S. and Gomez, Guillermo A. (2014). Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens. Cytoskeleton, 71 (12), 663-676. doi: 10.1002/cm.21202 |
2014 Journal Article Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctionsWu, Selwin K., Budnar, Srikanth, Yap, Alpha S. and Gomez, Guillermo A. (2014). Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions. European Journal of Cell Biology, 93 (10-12), 396-404. doi: 10.1016/j.ejcb.2014.09.001 |
2014 Journal Article Tension-sensitive actin assembly supports contractility at the epitherlial zonula adherensLeerberg, Joanne M., Gomez, Guillermo A., Verma, Suzie, Moussa, Elliott J., Wu, Selwin K., Priya, Rashmi, Hoffman, Brenton D., Grashoff, Carsten, Schwartz, Martin A. and Yap, Alpha S. (2014). Tension-sensitive actin assembly supports contractility at the epitherlial zonula adherens. Current Biology, 24 (15), 1689-1699. doi: 10.1016/j.cub.2014.06.028 |
2014 Journal Article E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transitionChen, Augustine, Beetham, Henry, Black, Michael A., Priya, Rashmi, Telford, Bryony J., Guest, Joanne, Wiggins, George A. R., Godwin, Tanis D., Yap, Alpha S. and Guilford, Parry J. (2014). E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition. BMC Cancer, 14 (1) 552. doi: 10.1186/1471-2407-14-552 |