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2015

Journal Article

Towards a dynamic understanding of cadherin-based mechanobiology

Hoffman, Brenton D. and Yap, Alpha S. (2015). Towards a dynamic understanding of cadherin-based mechanobiology. Trends in Cell Biology, 25 (12), 803-814. doi: 10.1016/j.tcb.2015.09.008

Towards a dynamic understanding of cadherin-based mechanobiology

2015

Journal Article

Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes

Marta Kubala, Norwood, Suzanne, Gomez, Guillermo, Jones, Alun, Johnston, Wayne A., Yap, Alpha S.K., Mureev, Sergey and Alexandrov, Kirill (2015). Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes. Biochemical and Biophysical Research Communications, 468 (4), 580-586. doi: 10.1016/j.bbrc.2015.10.148

Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes

2015

Journal Article

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies

Yap, Alpha S., Gomez, Guillermo A. and Parton, Robert G. (2015). Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies. Developmental Cell, 35 (1) 3402, 12-20. doi: 10.1016/j.devcel.2015.09.012

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies

2015

Journal Article

Modelling wound closure in an epithelial cell sheet using the cellular Potts model

Noppe, Adrian R., Roberts, Anthony P., Yap, Alpha S., Gomez, Guillermo A. and Neufeld, Zoltan (2015). Modelling wound closure in an epithelial cell sheet using the cellular Potts model. Integrative Biology (United Kingdom), 7 (10), 1253-1264. doi: 10.1039/c5ib00053j

Modelling wound closure in an epithelial cell sheet using the cellular Potts model

2015

Journal Article

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions

Priya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Verma, Suzie, Cox, Hayley L., Hamilton, Nicholas A. and Yap, Alpha S. (2015). Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nature Cell Biology, 17 (10), 1282-1293. doi: 10.1038/ncb3239

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions

2015

Journal Article

Making a choice: how cadherin switching controls cell migration

Priya, Rashmi and Yap, Alpha S. (2015). Making a choice: how cadherin switching controls cell migration. Developmental Cell, 34 (4) 3369, 383-384. doi: 10.1016/j.devcel.2015.08.002

Making a choice: how cadherin switching controls cell migration

2015

Journal Article

Seeing and believing: recent advances in imaging cell-cell interactions

Yap, Alpha S., Michael, Magdalene and Parton, Robert G. (2015). Seeing and believing: recent advances in imaging cell-cell interactions. F1000Research, 4 (F1000 Faculty Rev) 273, 273.1-273.8. doi: 10.12688/f1000research.6435.1

Seeing and believing: recent advances in imaging cell-cell interactions

2015

Journal Article

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization

Greenlees, Rebecca, Mihelec, Marija, Yousoof, Saira, Speidel, Daniel, Wu, Selwin K., Rinkwitz, Silke, Prokudin, Ivan, Perveen, Rahat, Cheng, Anson, Ma, Alan, Nash, Benjamin, Gillespie, Rachel, Loebel, David A. F., Clayton-Smith, Jill, Lloyd, I. Christopher, Grigg, John R., Tam, Patrick P. L., Yap, Alpha S., Becker, Thomas S., Black, Graeme C. M., Semina, Elena and Jamieson, Robyn V. (2015). Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization. Human Molecular Genetics, 24 (20), 5789-5804. doi: 10.1093/hmg/ddv298

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization

2015

Journal Article

E-cadherin junctions as active mechanical integrators in tissue dynamics

Lecuit, Thomas and Yap, Alpha S. (2015). E-cadherin junctions as active mechanical integrators in tissue dynamics. Nature Cell Biology, 17 (5), 533-539. doi: 10.1038/ncb3136

E-cadherin junctions as active mechanical integrators in tissue dynamics

2015

Journal Article

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

Gomez, Guillermo A., McLachlan, Robert W., Wu, Selwin K., Caldwell, Benjamin J., Moussa, Elliott, Verma, Suzie, Bastiani, Michele, Priya, Rashmi, Parton, Robert G., Gaus, Katharina, Sap, Jan and Yap, Alpha S. (2015). An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions. Molecular Biology of the Cell, 26 (7), 1249-1262. doi: 10.1091/mbc.E14-07-1223

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

2015

Journal Article

Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafish

Koltowska, Katarzyna, Lagendijk, Anne K., Pichol-Thievend, Cathy, Fischer, Johanna C., Francois, Mathias, Ober, Elke A., Yap, Alpha S. and Hogan, Benjamin M. (2015). Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafish. Cell Reports, 13 (9), 1828-1841. doi: 10.1016/j.celrep.2015.10.055

Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafish

2015

Journal Article

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

Papadopulos, Andreas, Gomez, Guillermo A., Martin, Sally, Jackson, Jade, Gormal, Rachel S., Keating, Damien J., Yap, Alpha S. and Meunier, Frederic A. (2015). Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking. Nature Communications, 6 (6297) 6297, 1-11. doi: 10.1038/ncomms7297

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

2015

Journal Article

Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer

Wu, Selwin K., Lagendijk, Anne K., Hogan, Benjamin M., Gomez, Guillermo A. and Yap, Alpha S. (2015). Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer. Cell Cycle, 14 (3), 315-322. doi: 10.4161/15384101.2014.989127

Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer

2015

Journal Article

Current perspectives on cadherin-cytoskeleton interactions and dynamics

Liang, Xuan, Gomez, Guillermo A. and Yap, Alpha S. (2015). Current perspectives on cadherin-cytoskeleton interactions and dynamics. Cell Health and Cytoskeleton, 7, 11-24. doi: 10.2147/CHC.S76107

Current perspectives on cadherin-cytoskeleton interactions and dynamics

2015

Journal Article

Preface

Yap, Alpha S. (2015). Preface. Cellular Adhesion in Development and Disease, 112, XV-XVII. doi: 10.1016/S0070-2153(15)00024-1

Preface

2014

Journal Article

Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctions

Moore, Thomas, Wu, Selwin, Michael, Magdalene, Yap, Alpha S.K., Gomez, Guillermo A. and Neufeld, Zoltan (2014). Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctions. Biophysical Journal, 107 (11), 2652-2661. doi: 10.1016/j.bpj.2014.10.045

Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctions

2014

Journal Article

Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens

Caldwell, Benjamin J., Lucas, Christine, Kee, Anthony J., Gaus, Katharina, Gunning, Peter W., Hardeman, Edna C., Yap, Alpha S. and Gomez, Guillermo A. (2014). Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens. Cytoskeleton, 71 (12), 663-676. doi: 10.1002/cm.21202

Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens

2014

Journal Article

Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions

Wu, Selwin K., Budnar, Srikanth, Yap, Alpha S. and Gomez, Guillermo A. (2014). Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions. European Journal of Cell Biology, 93 (10-12), 396-404. doi: 10.1016/j.ejcb.2014.09.001

Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions

2014

Journal Article

Tension-sensitive actin assembly supports contractility at the epitherlial zonula adherens

Leerberg, Joanne M., Gomez, Guillermo A., Verma, Suzie, Moussa, Elliott J., Wu, Selwin K., Priya, Rashmi, Hoffman, Brenton D., Grashoff, Carsten, Schwartz, Martin A. and Yap, Alpha S. (2014). Tension-sensitive actin assembly supports contractility at the epitherlial zonula adherens. Current Biology, 24 (15), 1689-1699. doi: 10.1016/j.cub.2014.06.028

Tension-sensitive actin assembly supports contractility at the epitherlial zonula adherens

2014

Journal Article

E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition

Chen, Augustine, Beetham, Henry, Black, Michael A., Priya, Rashmi, Telford, Bryony J., Guest, Joanne, Wiggins, George A. R., Godwin, Tanis D., Yap, Alpha S. and Guilford, Parry J. (2014). E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition. BMC Cancer, 14 (1) 552. doi: 10.1186/1471-2407-14-552

E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition