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2013 Journal Article Designing a multicomponent spray-dried formulation platform for pulmonary delivery of biomacromolecules: the effect of polymers on the formation of an amorphous matrix for glassy state stabilization of biomacromoleculesSou, Tomás, McIntosh, Michelle P., Kaminskas, Lisa M., Prankerd, Richard J. and Morton, David A. V. (2013). Designing a multicomponent spray-dried formulation platform for pulmonary delivery of biomacromolecules: the effect of polymers on the formation of an amorphous matrix for glassy state stabilization of biomacromolecules. Drying Technology, 31 (13-14), 1451-1458. doi: 10.1080/07373937.2013.788019 |
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2013 Journal Article Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependentRyan, Gemma M., Kaminskas, Lisa M., Kelly, Brian D., Owen, David J., McIntosh, Michelle P. and Porter, Christopher J. H. (2013). Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependent. Molecular Pharmaceutics, 10 (8), 2986-2995. doi: 10.1021/mp400091n |
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2013 Journal Article Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniaeVelkov, Tony, Deris, Zakuan Z., Huang, Johnny X., Azad, Mohammad A. K., Butler, Mark, Sivanesan, Sivashangarie, Kiminskas, Lisa M., Dong, Yao-Da, Boyd, Ben, Baker, Mark A., Cooper, Matthew A., Nation, Roger L. and Li, Jian (2013). Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae. Innate Immunity, 20 (4), 350-363. doi: 10.1177/1753425913493337 |
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2013 Journal Article PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastasesKaminskas, Lisa M., Ascher, David B., McLeod, Victoria M., Herold, Marco J., Le, Caroline P., Sloan, Erica K. and Porter, Christopher J. H. (2013). PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases. Journal of Controlled Release, 168 (2), 200-208. doi: 10.1016/j.jconrel.2013.03.006 |
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2013 Journal Article The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromoleculesSou, Tomás, Kaminskas, Lisa M., Nguyen, Tri-Hung, Carlberg, Renée, McIntosh, Michelle P. and Morton, David A.V. (2013). The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules. European Journal of Pharmaceutics and Biopharmaceutics, 83 (2), 234-243. doi: 10.1016/j.ejpb.2012.10.015 |
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2012 Journal Article Chaperone heat shock protein 90 mobilization and hydralazine cytoprotection against acrolein-induced carbonyl stressBurcham, Philip C., Raso, Albert and Kaminskas, Lisa M. (2012). Chaperone heat shock protein 90 mobilization and hydralazine cytoprotection against acrolein-induced carbonyl stress. Molecular Pharmacology, 82 (5), 876-886. doi: 10.1124/mol.112.078956 |
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2012 Journal Article Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor modelsKaminskas, Lisa M., McLeod, Victoria M., Kelly, Brian D., Cullinane, Carleen, Sberna, Gian, Williamson, Mark, Boyd, Ben J., Owen, David J. and Porter, Christopher J. H. (2012). Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor models. Molecular Pharmaceutics, 9 (3), 422-432. doi: 10.1021/mp200522d |
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2012 Journal Article Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulationKaminskas, Lisa M., McLeod, Victoria M., Porter, Christopher J. H. and Boyd, Ben J. (2012). Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulation. Molecular Pharmaceutics, 9 (3), 355-373. doi: 10.1021/mp2005966 |
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2012 Journal Article Erratum: Dendrimer pharmacokinetics: The effect of size, structure and surface characteristics on ADME properties (Nanomedicine (2011) 6:6 (1063-1084))Kaminskas, Lisa M., Boyd, Ben J. and Porter, Christopher J.H. (2012). Erratum: Dendrimer pharmacokinetics: The effect of size, structure and surface characteristics on ADME properties (Nanomedicine (2011) 6:6 (1063-1084)). Nanomedicine, 7 (1). doi: 10.2217/nnm.11.173 |
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2012 Journal Article A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systemsKaminskas, Lisa M., McLeod, Victoria M., Kelly, Brian D., Sberna, Gian, Boyd, Ben J., Williamson, Mark, Owen, David J. and Porter, Christopher J. H. (2012). A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems. Nanomedicine: Nanotechnology, Biology and Medicine, 8 (1), 103-111. doi: 10.1016/j.nano.2011.05.013 |
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2011 Journal Article Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: a design of experiment approachSou, Tomas, Orlando, Laurence, McIntosh, Michelle P., Kaminskas, Lisa M. and Morton, David A. V. (2011). Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: a design of experiment approach. International Journal of Pharmaceutics, 421 (2), 220-229. doi: 10.1016/j.ijpharm.2011.09.018 |
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2011 Journal Article Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearanceKaminskas, Lisa M., Mcleod, Victoria M., Porter, Christopher J. H. and Boyd, Ben J. (2011). Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearance. Journal of Pharmaceutical Sciences, 100 (11), 5069-5077. doi: 10.1002/jps.22682 |
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2011 Journal Article Targeting the lymphatics using dendritic polymers (dendrimers)Kaminskas, Lisa M. and Porter, Christopher J. H. (2011). Targeting the lymphatics using dendritic polymers (dendrimers). Advanced Drug Delivery Reviews, 63 (10-11), 890-900. doi: 10.1016/j.addr.2011.05.016 |
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2011 Journal Article Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME propertiesKaminskas, Lisa M., Boyd, Ben J. and Porter, Christopher J. H. (2011). Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties. Nanomedicine, 6 (6), 1063-1084. doi: 10.2217/nnm.11.67 |
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2011 Journal Article Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linkerKaminskas, Lisa M., Kelly, Brian D., McLeod, Victoria M., Sberna, Gian, Owen, David J., Boyd, Ben J. and Porter, Christopher J. H. (2011). Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker. Journal of Controlled Release, 152 (2), 241-248. doi: 10.1016/j.jconrel.2011.02.005 |
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2011 Journal Article New developments in dry powder pulmonary vaccine deliverySou, Tomas, Meeusen, Els N., de Veer, Michael, Morton, David A. V., Kaminskas, Lisa M. and McIntosh, Michelle P. (2011). New developments in dry powder pulmonary vaccine delivery. Trends in Biotechnology, 29 (4), 191-198. doi: 10.1016/j.tibtech.2010.12.009 |
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2011 Journal Article Capping methotrexate α-carboxyl groups enhances systemic exposure and retains the cytotoxicity of drug conjugated pegylated polylysine dendrimersKaminskas, Lisa M., Kelly, Brian D., McLeod, Victoria M., Sberna, Gian, Boyd, Ben J., Owen, David J. and Porter, Christopher J. H. (2011). Capping methotrexate α-carboxyl groups enhances systemic exposure and retains the cytotoxicity of drug conjugated pegylated polylysine dendrimers. Molecular Pharmaceutics, 8 (2), 338-349. doi: 10.1021/mp1001872 |
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2009 Journal Article PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in ratsKaminskas, Lisa M., Kota, Jagannath, McLeod, Victoria M., Kelly, Brian D., Karellas, Peter and Porter, Christopher J. H. (2009). PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats. Journal of Controlled Release, 140 (2), 108-116. doi: 10.1016/j.jconrel.2009.08.005 |
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2009 Journal Article Partly-PEGylated poly-L-lysine dendrimers have reduced plasma stability and circulation times compared with fully PEGylated dendrimersKaminskas, L. M., Wu, Z., Barlow, N., Krippner, G. Y., Boyd, B. J. and Porter, C. J. H. (2009). Partly-PEGylated poly-L-lysine dendrimers have reduced plasma stability and circulation times compared with fully PEGylated dendrimers. Journal of Pharmaceutical Sciences, 98 (10), 3871-3875. doi: 10.1002/jps.21692 |
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2009 Journal Article Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly-L-lysine dendrimersKaminskas, Lisa M., Kelly, Brian D., McLeod, Victoria M., Boyd, Ben J., Krippner, Guy Y., Williams, Elizabeth D. and Porter, Christopher J. H. (2009). Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly-L-lysine dendrimers. Molecular Pharmaceutics, 6 (4), 1190-1204. doi: 10.1021/mp900049a |
