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2008

Journal Article

The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of pegylated poly L-lysine dendrimers

Kaminskas, Lisa M., Boyd, Ben J., Karellas, Peter, Krippner, Guy Y., Lessene, Romina, Kelly, Brian and Porter, Chrisiopher J. H. (2008). The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of pegylated poly L-lysine dendrimers. Molecular Pharmaceutics, 5 (3), 449-463. doi: 10.1021/mp7001208

The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of pegylated poly L-lysine dendrimers

2008

Journal Article

Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury

Burcham, P. C., Kaminskas, L. M., Tan, D. and Pyke, S. M. (2008). Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury. Mini-Reviews in Medicinal Chemistry, 8 (4), 319-330. doi: 10.2174/138955708783955953

Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury

2007

Journal Article

Impact of surface derivatization of poly-L-lysine dendrimers with anionic arylsulfonate or succinate groups on intravenous pharmacokinetics and disposition

Kaminskas, Lisa M., Boyd, Ben J., Karellas, Peter, Henderson, Scott A., Giannis, Michael P., Krippner, Guy Y. and Porter, Christopher J. H. (2007). Impact of surface derivatization of poly-L-lysine dendrimers with anionic arylsulfonate or succinate groups on intravenous pharmacokinetics and disposition. Molecular Pharmaceutics, 4 (6), 949-961. doi: 10.1021/mp070047s

Impact of surface derivatization of poly-L-lysine dendrimers with anionic arylsulfonate or succinate groups on intravenous pharmacokinetics and disposition

2007

Journal Article

Michael addition of acrolein to lysinyl and N-terminal residues of a model peptide: targets for cytoprotective hydrazino drugs

Kaminskas, Lisa M., Pyke, Simon M. and Burcham, Philip C. (2007). Michael addition of acrolein to lysinyl and N-terminal residues of a model peptide: targets for cytoprotective hydrazino drugs. Rapid Communications in Mass Spectrometry, 21 (7), 1155-1164. doi: 10.1002/rcm.2945

Michael addition of acrolein to lysinyl and N-terminal residues of a model peptide: targets for cytoprotective hydrazino drugs

2006

Journal Article

Cationic poly-L-lysine dendrimers: pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats

Boyd, Ben J., Kaminskas, Lisa M., Karellas, Peter, Krippner, Guy, Lessene, Romina and Porter, Christopher J. H. (2006). Cationic poly-L-lysine dendrimers: pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats. Molecular Pharmaceutics, 3 (5), 614-627. doi: 10.1021/mp060032e

Cationic poly-L-lysine dendrimers: pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats

2005

Journal Article

Differences in lysine adduction by acrolein and methyl vinyl ketone: implications for cytotoxicity in cultured hepatocytes

Kaminskas, Lisa M., Pyke, Simon M. and Burcham, Philip C. (2005). Differences in lysine adduction by acrolein and methyl vinyl ketone: implications for cytotoxicity in cultured hepatocytes. Chemical Research in Toxicology, 18 (11), 1627-1633. doi: 10.1021/tx0502387

Differences in lysine adduction by acrolein and methyl vinyl ketone: implications for cytotoxicity in cultured hepatocytes

2004

Journal Article

Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde

Kaminskas, Lisa M., Pyke, Simon M. and Burcham, Philip C. (2004). Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde. Organic and Biomolecular Chemistry, 2 (18), 2578-2584. doi: 10.1039/b408796h

Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde

2004

Journal Article

Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice

Kaminskas, Lisa M., Pyke, Simon M. and Burcham, Philip C. (2004). Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice. Journal of Pharmacology and Experimental Therapeutics, 310 (3), 1003-1010. doi: 10.1124/jpet.104.067330

Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice

2004

Journal Article

Protein Adduct-Trapping by Hydrazinophthalazine Drugs: Mechanisms of Cytoprotection Against Acrolein-Mediated Toxicity

Burcham, Philip C., Fontaine, Frank R., Kaminskas, Lisa M., Petersen, Dennis R. and Pyke, Simon M. (2004). Protein Adduct-Trapping by Hydrazinophthalazine Drugs: Mechanisms of Cytoprotection Against Acrolein-Mediated Toxicity. Molecular Pharmacology, 65 (3), 655-664. doi: 10.1124/mol.65.3.655

Protein Adduct-Trapping by Hydrazinophthalazine Drugs: Mechanisms of Cytoprotection Against Acrolein-Mediated Toxicity

2002

Journal Article

Aldehyde-Sequestering Drugs: Tools for Studying Protein Damage by Lipid Peroxidation Products

Burcham, Philip C., Kaminskas, Lisa M., Fontaine, Frank R., Petersen, Dennis R. and Pyke, Simon M. (2002). Aldehyde-Sequestering Drugs: Tools for Studying Protein Damage by Lipid Peroxidation Products. Toxicology, 181-182, 229-236. doi: 10.1016/S0300-483X(02)00287-1

Aldehyde-Sequestering Drugs: Tools for Studying Protein Damage by Lipid Peroxidation Products

2002

Journal Article

The contribution of the metabolitep-hydroxyamphetamine to the central actions ofp-methoxyamphetamine

Kaminskas, Lisa M., Irvine, Rodney J., Callaghan, Paul D., White, Jason M. and Kirkbride, Paul (2002). The contribution of the metabolitep-hydroxyamphetamine to the central actions ofp-methoxyamphetamine. Psychopharmacology, 160 (2), 155-160. doi: 10.1007/s00213-001-0984-z

The contribution of the metabolitep-hydroxyamphetamine to the central actions ofp-methoxyamphetamine

2000

Journal Article

Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions

Gamble, Jennifer R., Drew, Jenny, Trezise, Libby, Underwood, Anne, Parsons, Michelle, Kasminkas, Lisa, Rudge, John, Yancopoulos, George and Vadas, Mathew A. (2000). Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions. Circulation research, 87 (7), 603-607. doi: 10.1161/01.res.87.7.603

Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions