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2020

Journal Article

How to stimulate and facilitate early stage antibiotic discovery

Zuegg, Johannes, Hansford, Karl A., Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). How to stimulate and facilitate early stage antibiotic discovery. ACS Infectious Diseases, 6 (6), 1302-1304. doi: 10.1021/acsinfecdis.0c00163

How to stimulate and facilitate early stage antibiotic discovery

2020

Journal Article

Metal complexes as a promising source for new antibiotics

Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray V., Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher Gerard, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed Moustafa, Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna, Rutledge, Peter, Sadler, Peter J., Todd, Matthew Houghton, Willans, Charlotte E., Wilson, Justin Jeff, Cooper, Matthew Allister and Blaskovich, Mark (2020). Metal complexes as a promising source for new antibiotics. Chemical Science, 11 (10), 2627-2639. doi: 10.1039/c9sc06460e

Metal complexes as a promising source for new antibiotics

2019

Journal Article

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Stone, M. Rhia L., Masi, Muriel, Phetsang, Wanida, Pagès, Jean-Marie, Cooper, Matthew A. and Blaskovich, Mark A. T. (2019). Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux. MedChemComm, 10 (6), 901-906. doi: 10.1039/c9md00124g

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

2019

Journal Article

The diminished antimicrobial pipeline

Blaskovich, Mark A.T. (2019). The diminished antimicrobial pipeline. Microbiology Australia, 40 (2), 92-96. doi: 10.1071/MA19025

The diminished antimicrobial pipeline

2018

Journal Article

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

Blaskovich, Mark A. T., Pitt, Miranda E., Elliott, Alysha G. and Cooper, Matthew A. (2018). Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?. Expert Review of Anti-infective Therapy, 16 (6), 485-499. doi: 10.1080/14787210.2018.1483240

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

2018

Journal Article

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

Stone, M Rhia L., Butler, Mark S., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2018). Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance. Trends in Biotechnology, 36 (5), 523-536. doi: 10.1016/j.tibtech.2018.01.004

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

Featured

2018

Journal Article

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria

Velkov, Tony, Gallardo-Godoy, Alejandra, Swarbrick, James D., Blaskovich, Mark A. T., Elliott, Alysha G., Han, Meiling, Thompson, Philip E., Roberts, Kade D., Huang, Johnny X., Becker, Bernd, Butler, Mark S., Lash, Lawrence H., Henriques, Sónia Troeira, Nation, Roger L., Sivanesan, Sivashangarie, Sani, Marc-Antoine, Separovic, Frances, Mertens, Haydyn, Bulach, Dieter, Seemann, Torsten, Owen, Jeremy, Li, Jian and Cooper, Matthew A. (2018). Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria. Cell Chemical Biology, 25 (4), 380-391.e5. doi: 10.1016/j.chembiol.2018.01.005

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria

2018

Journal Article

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

2016

Journal Article

Unusual amino acids in medicinal chemistry

Blaskovich, Mark A. T. (2016). Unusual amino acids in medicinal chemistry. Journal of Medicinal Chemistry, 59 (24), 10807-10836. doi: 10.1021/acs.jmedchem.6b00319

Unusual amino acids in medicinal chemistry

2016

Journal Article

Antibiotics in the clinical pipeline at the end of 2015

Butler, Mark S., Blaskovich, Mark A. T. and Cooper, Matthew A. (2016). Antibiotics in the clinical pipeline at the end of 2015. The Journal of Antibiotics, 70 (1), 1-22. doi: 10.1038/ja.2016.72

Antibiotics in the clinical pipeline at the end of 2015

2016

Journal Article

Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli

Phetsang, Wanida, Pelingon, Ruby, Butler, Mark S., KC, Sanjaya, Pitt, Miranda, Kaeslin, Geraldine, Cooper, Matthew A. and Blaskovich, Mark A. T. (2016). Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli. ACS Infectious Diseases, 2 (10), 688-701. doi: 10.1021/acsinfecdis.6b00080

Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli

2025

Journal Article

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Yadav, Sharda, KC, Sanjaya, Blaskovich, Mark A. T., Lu, Cu‐tai, Lam, Alfred K and Nguyen, Nam‐Trung (2025). RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer. Advanced Biology, e2400626. doi: 10.1002/adbi.202400626

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

2024

Journal Article

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

Floyd, Holly E. E., Kavanagh, Angela M., Lowe, Gabrielle J., Amado, Maite, Fraser, James A., Blaskovich, Mark A. T., Elliott, Alysha G. and Zuegg, Johannes (2024). Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans. Scientific Reports, 14 (1) 23407. doi: 10.1038/s41598-024-74068-2

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

2024

Journal Article

Adjuvant strategies to tackle mcr-mediated polymyxin resistance

Nuske, Madison R., Zhong, Junlang, Huang, Renjie, Sarojini, Vijayalekshmi, Chen, Jack L. Y., Squire, Christopher J., Blaskovich, Mark A. T. and Leung, Ivanhoe K. H. (2024). Adjuvant strategies to tackle mcr-mediated polymyxin resistance. RSC Medicinal Chemistry, 16 (2), 465-480. doi: 10.1039/d4md00654b

Adjuvant strategies to tackle mcr-mediated polymyxin resistance

2024

Journal Article

A review of antibacterial candidates with new modes of action

Butler, Mark S., Vollmer, Waldemar, Goodall, Emily C. A., Capon, Robert J., Henderson, Ian R. and Blaskovich, Mark A. T. (2024). A review of antibacterial candidates with new modes of action. ACS Infectious Diseases, 10 (10), 3440-3474. doi: 10.1021/acsinfecdis.4c00218

A review of antibacterial candidates with new modes of action

2024

Journal Article

Tetrazoles: A multi-potent motif in drug design

Yuan, Ye, Li, Muzi, Apostolopoulos, Vasso, Matsoukas, John, Wolf, Wojciech M., Blaskovich, Mark A.T., Bojarska, Joanna and Ziora, Zyta M. (2024). Tetrazoles: A multi-potent motif in drug design. European Journal of Medicinal Chemistry, 279 116870, 116870. doi: 10.1016/j.ejmech.2024.116870

Tetrazoles: A multi-potent motif in drug design

2024

Journal Article

Modelling and statistical interpretation of phenol adsorption behaviour of 3-Dimensional hybrid aerogel of waste-derived carbon nanotubes and graphene oxide

Jain, Marut, Sahoo, Abhisek, Mishra, Deepti, Aiman Khan, Sadaf, Kishore Pant, Kamal, Ziora, Zyta M. and Blaskovich, Mark A.T. (2024). Modelling and statistical interpretation of phenol adsorption behaviour of 3-Dimensional hybrid aerogel of waste-derived carbon nanotubes and graphene oxide. Chemical Engineering Journal, 490 151351, 1-17. doi: 10.1016/j.cej.2024.151351

Modelling and statistical interpretation of phenol adsorption behaviour of 3-Dimensional hybrid aerogel of waste-derived carbon nanotubes and graphene oxide

2024

Journal Article

Facile one-pot fabrication of multifunctional silver nanoparticles utilizing biowaste for efficient pollutant degradation, heavy metal sensing, and bactericidal activity

Khan, Sadaf Aiman, Zeng, Junya, Jain, Marut, Pant, Kamal Kishore, Ziora, Zyta Maria, Blaskovich, Mark A.T. and Seneviratne, Chaminda Jayampath (2024). Facile one-pot fabrication of multifunctional silver nanoparticles utilizing biowaste for efficient pollutant degradation, heavy metal sensing, and bactericidal activity. Materials Chemistry and Physics, 322 129606, 129606. doi: 10.1016/j.matchemphys.2024.129606

Facile one-pot fabrication of multifunctional silver nanoparticles utilizing biowaste for efficient pollutant degradation, heavy metal sensing, and bactericidal activity

2024

Journal Article

Phage-induced efflux down-regulation boosts antibiotic efficacy

Kraus, Samuel, Fletcher, Megan L., Łapińska, Urszula, Chawla, Krina, Baker, Evan, Attrill, Erin L., O’Neill, Paul, Farbos, Audrey, Jeffries, Aaron, Galyov, Edouard E., Korbsrisate, Sunee, Barnes, Kay B., Harding, Sarah V., Tsaneva-Atanasova, Krasimira, Blaskovich, Mark A.T. and Pagliara, Stefano (2024). Phage-induced efflux down-regulation boosts antibiotic efficacy. PLoS Pathogens, 20 (6 June) e1012361, e1012361. doi: 10.1371/journal.ppat.1012361

Phage-induced efflux down-regulation boosts antibiotic efficacy

2024

Journal Article

New antibiotics to combat One Health AMR

Ogunniyi, Abiodun David, Venter, Henrietta and Blaskovich, Mark A. T. (2024). New antibiotics to combat One Health AMR. Microbiology Australia, 45 (2), 74-78. doi: 10.1071/ma24022

New antibiotics to combat One Health AMR