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2015

Journal Article

Helping chemists discover new antibiotics

Blaskovich, Mark A. T., Zuegg, Johannes, Elliott, Alysha G. and Cooper, Matthew (2015). Helping chemists discover new antibiotics. ACS Infectious Diseases, 1 (7), 285-287. doi: 10.1021/acsinfecdis.5b00044

Helping chemists discover new antibiotics

2015

Journal Article

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

Huang, Johnny Xiao, Geraldine Kaeslin, Max Ranall, Blaskovich, Mark, Bernd Becker, Butler, Mark, Little, Melissa H., Lash, Lawrence H. and Cooper, Matthew (2015). Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells. Pharmacology Research and Perspectives, 3 (3) e00148, e00148. doi: 10.1002/prp2.148

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

2015

Journal Article

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains

Azmi, Fazren, Elliott, Alysha G., Khalil, Zeinab G., Hussein, Waleed M., Kavanagh, Angela, Huang, Johnny X., Quezada, Michelle, Blaskovich, Mark A. T., Capon, Robert J., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2015). Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains. Nanomedicine, 10 (22), 3359-3371. doi: 10.2217/nnm.15.137

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains

2014

Journal Article

Cell- and biomarker-based assays for predicting nephrotoxicity

Huang, Johnny X., Blaskovich, Mark A. and Cooper, Matthew A. (2014). Cell- and biomarker-based assays for predicting nephrotoxicity. Expert Opinion on Drug Metabolism and Toxicology, 10 (12), 1621-1635. doi: 10.1517/17425255.2014.967681

Cell- and biomarker-based assays for predicting nephrotoxicity

2014

Journal Article

Glycopeptide antibiotics: back to the future

Butler, Mark S., Hansford, Karl A., Blaskovich, Mark A. T., Halai, Reena and Cooper, Matthew A. (2014). Glycopeptide antibiotics: back to the future. Journal of Antibiotics, 67 (9), 631-644. doi: 10.1038/ja.2014.111

Glycopeptide antibiotics: back to the future

2014

Journal Article

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

Phetsang, Wanida, Blaskovich, Mark A. T., Butler, Mark S., Huang, Johnny Xiao, Zuegg, Johannes, Mamidyala, Sreeman K., Ramu, Soumya, Kavanagh, Angela M. and Cooper, Matthew A. (2014). An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants. Bioorganic and Medicinal Chemistry, 22 (16), 4490-4498. doi: 10.1016/j.bmc.2014.05.054

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

2014

Journal Article

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

Cheng, Mu, Ziora, Zyta M., Hansford, Karl A., Blaskovich, Mark A., Butler, Mark S. and Cooper, Matthew A. (2014). Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin. Organic and Biomolecular Chemistry, 12 (16), 2568-2575. doi: 10.1039/c3ob42428f

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin

2013

Journal Article

ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2013). ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery. ChemInform, 44 (43), no-no. doi: 10.1002/chin.201343267

ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery

2013

Journal Article

Antibiotics in the clinical pipeline in 2013

Butler, Mark S., Blaskovich, Mark A. and Cooper, Matthew A. (2013). Antibiotics in the clinical pipeline in 2013. Journal of Antibiotics, 66 (10), 571-591. doi: 10.1038/ja.2013.86

Antibiotics in the clinical pipeline in 2013

2013

Journal Article

Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca

Barnes, Emma C., Kavanagh, Angela M., Ramu, Soumya, Blaskovich, Mark A., Cooper, Matthew A. and Davis, Rohan A. (2013). Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca. Phytochemistry, 93, 162-169. doi: 10.1016/j.phytochem.2013.02.021

Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca

2012

Journal Article

Resolving biofilm infections: current therapy and drug discovery strategies

Ranall, Max V., Butler, Mark S., Blaskovich, Mark A. and Cooper, Matthew A. (2012). Resolving biofilm infections: current therapy and drug discovery strategies. Current Drug Targets, 13 (11), 1375-1385. doi: 10.2174/138945012803530251

Resolving biofilm infections: current therapy and drug discovery strategies

2012

Journal Article

Lipoamino acids as major components of absorption promoters in drug delivery

Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2012). Lipoamino acids as major components of absorption promoters in drug delivery. Current Topics in Medicinal Chemistry, 12 (14), 1562-1580. doi: 10.2174/156802612802652448

Lipoamino acids as major components of absorption promoters in drug delivery

2009

Journal Article

Drug discovery and protein tyrosine phosphatases

Blaskovich, M. A. T. (2009). Drug discovery and protein tyrosine phosphatases. Current Medicinal Chemistry, 16 (17), 2095-2176. doi: 10.2174/092986709788612693

Drug discovery and protein tyrosine phosphatases

2008

Journal Article

A convenient reduction of α-amino acids to 1,2-amino alcohols with retention of optical purity

Hwang, Sun-Hee, Blaskovich, Mark A. and Kim, Hwa-Ok (2008). A convenient reduction of α-amino acids to 1,2-amino alcohols with retention of optical purity. Open Organic Chemistry Journal, 2 (1), 107-109. doi: 10.2174/1874095200802010107

A convenient reduction of α-amino acids to 1,2-amino alcohols with retention of optical purity

2003

Journal Article

Design and synthesis of phosphotyrosine mimetics

Yan, Zheng, Kahn, Michael, Qabar, Maher, Urban, Jan, Kim, Hwa-Ok and Blaskovich, Mark (2003). Design and synthesis of phosphotyrosine mimetics. Bioorganic & Medicinal Chemistry Letters, 13 (12), 2083-2085. doi: 10.1016/S0960-894X(03)00253-1

Design and synthesis of phosphotyrosine mimetics

2002

Journal Article

Recent discovery and development of protein tyrosine phosphatase inhibitors

Blaskovich, Mark A. and Kim, Hwa-Ok (2002). Recent discovery and development of protein tyrosine phosphatase inhibitors. Expert Opinion on Therapeutic Patents, 12 (6), 871-905. doi: 10.1517/13543776.12.6.871

Recent discovery and development of protein tyrosine phosphatase inhibitors

2002

Journal Article

Preparation of 1-[N-Benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo-[2.2.2]octane

Rose, Nicholas G.W., Blaskovich, Mark A., Evindar, Ghotas, Wilkinson, Scott, Luo, Yue, Reid, C. and Lajoie, Gilles A. (2002). Preparation of 1-[N-Benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo-[2.2.2]octane. Organic syntheses, 79, 216-221. doi: 10.1002/0471264180.os079.26

Preparation of 1-[N-Benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo-[2.2.2]octane

2002

Journal Article

Preparation of 1-[N-benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo[2.2.2] octane: [Carbamic acid, [1-(4-methyl-2,6,7-trioxabicyclo[2.2.2]oct-1-yl)-2-oxoethyl]-, phenylmethyl ester, (S)-]

Rose, Nicholas G. W., Blaskovich, Mark A., Evindar, Ghotas, Wilkinson, Scott, Luo, Yue, Fishlock, Dan, Reid, Chris, Lajoie, Gilles A., Gordon, Richard S. and Holmes, Andrew B. (2002). Preparation of 1-[N-benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo[2.2.2] octane: [Carbamic acid, [1-(4-methyl-2,6,7-trioxabicyclo[2.2.2]oct-1-yl)-2-oxoethyl]-, phenylmethyl ester, (S)-]. Organic Syntheses, 79 doi: 10.15227/orgsyn.079.0216

Preparation of 1-[N-benzyloxycarbonyl-(1S)-1-amino-2-oxoethyl]-4-methyl-2,6,7-trioxabicyclo[2.2.2] octane: [Carbamic acid, [1-(4-methyl-2,6,7-trioxabicyclo[2.2.2]oct-1-yl)-2-oxoethyl]-, phenylmethyl ester, (S)-]

2001

Journal Article

Synthesis of enantiomerically enriched beta,gamma-unsaturated-alpha-amino acids

Rose, Ngw, Blaskovich, MA, Wong, A and Lajoie, GA (2001). Synthesis of enantiomerically enriched beta,gamma-unsaturated-alpha-amino acids. Tetrahedron, 57 (8), 1497-1507. doi: 10.1016/S0040-4020(00)01146-7

Synthesis of enantiomerically enriched beta,gamma-unsaturated-alpha-amino acids

1999

Journal Article

Stereoselective synthesis of beta-substituted alpha,beta-diamino acids from beta-hydroxy amino acids

Luo, Y, Blaskovich, MA and Lajoie, GA (1999). Stereoselective synthesis of beta-substituted alpha,beta-diamino acids from beta-hydroxy amino acids. Journal of Organic Chemistry, 64 (16), 6106-6111. doi: 10.1021/jo9904718

Stereoselective synthesis of beta-substituted alpha,beta-diamino acids from beta-hydroxy amino acids