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2015 Journal Article Clostridium difficile infection: current and emerging therapeuticsJarrad, Angie M., Blaskovich, Mark A. T., Lyras, Dena and Cooper, Matthew A. (2015). Clostridium difficile infection: current and emerging therapeutics. Current Treatment Options in Infectious Diseases, 7 (4), 317-334. doi: 10.1007/s40506-015-0062-4 |
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2015 Journal Article Mucin binding reduces colistin antimicrobial activityHuang, Johnny X., Blaskovich, Mark A.T., Pelingon, Ruby, Ramu, Soumya, Kavanagh, Angela, Elliott, Alysha G., Butler, Mark S., Montgomery, A. Bruce and Cooper, Matthew A. (2015). Mucin binding reduces colistin antimicrobial activity. Antimicrobial Agents and Chemotherapy, 59 (10), 5925-5931. doi: 10.1128/AAC.00808-15 |
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2015 Journal Article Metronidazole-triazole conjugates: activity against Clostridium difficile and parasitesJarrad, Angie M., Karoli, Tomislav, Anjan, Debnath, Tay, Chin Yen, Huang, Johnny X., Kaeslin, Geraldine, Elliott, Alysha G., Miyamoto, Yukiko, Ramu, Soumya, Kavanagh, Angela M., Zuegg, Johannes, Eckmann, Lars, Blaskovich, Mark A. and Cooper, Matthew A. (2015). Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites. European Journal of Medicinal Chemistry, 101 7946, 96-102. doi: 10.1016/j.ejmech.2015.06.019 |
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2015 Journal Article Clostridium difficile drug pipeline: challenges in discover and development of new agentsJarrad, Angie M., Karoli, Tomislav, Blaskovich, Mark A.T., Lyras, Dena and Cooper, Matthew A. (2015). Clostridium difficile drug pipeline: challenges in discover and development of new agents. Journal of Medicinal Chemistry, 58 (13), 5164-5185. doi: 10.1021/jm5016846 |
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2015 Journal Article A new antibiotic with potent activity targets MscLIscla, Irene, Wray, Robin, Blount, Paul, Larkins-Ford, Johah, Conery, Annie L., Ausubel, Frederick M., Ramu, Soumya, Kavanagh, Angela, Huang, Johnny X., Blaskovich, Mark A., Cooper, Matthew A., Obregon-Henao, Andres, Orme, Ian, Tjandra, Edwin S., Stroeher, Uwe H., Brown, Melissa H., Macardle, Cindy, van Holst, Nick, Tong, Chee Ling, Slattery, Ashley D., Gibson, Christopher T., Raston, Colin L. and Boulos, Ramiz A. (2015). A new antibiotic with potent activity targets MscL. The Journal of Antibiotics, 68 (7), 453-462. doi: 10.1038/ja.2015.4 |
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2015 Journal Article Helping chemists discover new antibioticsBlaskovich, Mark A. T., Zuegg, Johannes, Elliott, Alysha G. and Cooper, Matthew (2015). Helping chemists discover new antibiotics. ACS Infectious Diseases, 1 (7), 285-287. doi: 10.1021/acsinfecdis.5b00044 |
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2015 Journal Article Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cellsHuang, Johnny Xiao, Geraldine Kaeslin, Max Ranall, Blaskovich, Mark, Bernd Becker, Butler, Mark, Little, Melissa H., Lash, Lawrence H. and Cooper, Matthew (2015). Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells. Pharmacology Research and Perspectives, 3 (3) e00148, e00148. doi: 10.1002/prp2.148 |
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2015 Journal Article Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strainsAzmi, Fazren, Elliott, Alysha G., Khalil, Zeinab G., Hussein, Waleed M., Kavanagh, Angela, Huang, Johnny X., Quezada, Michelle, Blaskovich, Mark A. T., Capon, Robert J., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2015). Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains. Nanomedicine, 10 (22), 3359-3371. doi: 10.2217/nnm.15.137 |
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2014 Journal Article Cell- and biomarker-based assays for predicting nephrotoxicityHuang, Johnny X., Blaskovich, Mark A. and Cooper, Matthew A. (2014). Cell- and biomarker-based assays for predicting nephrotoxicity. Expert Opinion on Drug Metabolism and Toxicology, 10 (12), 1621-1635. doi: 10.1517/17425255.2014.967681 |
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2014 Journal Article Glycopeptide antibiotics: back to the futureButler, Mark S., Hansford, Karl A., Blaskovich, Mark A. T., Halai, Reena and Cooper, Matthew A. (2014). Glycopeptide antibiotics: back to the future. Journal of Antibiotics, 67 (9), 631-644. doi: 10.1038/ja.2014.111 |
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2014 Journal Article An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variantsPhetsang, Wanida, Blaskovich, Mark A. T., Butler, Mark S., Huang, Johnny Xiao, Zuegg, Johannes, Mamidyala, Sreeman K., Ramu, Soumya, Kavanagh, Angela M. and Cooper, Matthew A. (2014). An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants. Bioorganic and Medicinal Chemistry, 22 (16), 4490-4498. doi: 10.1016/j.bmc.2014.05.054 |
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2014 Journal Article Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancinCheng, Mu, Ziora, Zyta M., Hansford, Karl A., Blaskovich, Mark A., Butler, Mark S. and Cooper, Matthew A. (2014). Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin. Organic and Biomolecular Chemistry, 12 (16), 2568-2575. doi: 10.1039/c3ob42428f |
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2013 Journal Article ChemInform abstract: lipoamino acids as major components of absorption promoters in drug deliveryZiora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2013). ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery. ChemInform, 44 (43), no-no. doi: 10.1002/chin.201343267 |
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2013 Journal Article Antibiotics in the clinical pipeline in 2013Butler, Mark S., Blaskovich, Mark A. and Cooper, Matthew A. (2013). Antibiotics in the clinical pipeline in 2013. Journal of Antibiotics, 66 (10), 571-591. doi: 10.1038/ja.2013.86 |
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2013 Journal Article Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microthecaBarnes, Emma C., Kavanagh, Angela M., Ramu, Soumya, Blaskovich, Mark A., Cooper, Matthew A. and Davis, Rohan A. (2013). Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca. Phytochemistry, 93, 162-169. doi: 10.1016/j.phytochem.2013.02.021 |
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2012 Journal Article Resolving biofilm infections: current therapy and drug discovery strategiesRanall, Max V., Butler, Mark S., Blaskovich, Mark A. and Cooper, Matthew A. (2012). Resolving biofilm infections: current therapy and drug discovery strategies. Current Drug Targets, 13 (11), 1375-1385. doi: 10.2174/138945012803530251 |
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2012 Journal Article Lipoamino acids as major components of absorption promoters in drug deliveryZiora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2012). Lipoamino acids as major components of absorption promoters in drug delivery. Current Topics in Medicinal Chemistry, 12 (14), 1562-1580. doi: 10.2174/156802612802652448 |
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2009 Journal Article Drug discovery and protein tyrosine phosphatasesBlaskovich, M. A. T. (2009). Drug discovery and protein tyrosine phosphatases. Current Medicinal Chemistry, 16 (17), 2095-2176. doi: 10.2174/092986709788612693 |
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2008 Journal Article A convenient reduction of α-amino acids to 1,2-amino alcohols with retention of optical purityHwang, Sun-Hee, Blaskovich, Mark A. and Kim, Hwa-Ok (2008). A convenient reduction of α-amino acids to 1,2-amino alcohols with retention of optical purity. Open Organic Chemistry Journal, 2 (1), 107-109. doi: 10.2174/1874095200802010107 |
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2003 Journal Article Design and synthesis of phosphotyrosine mimeticsYan, Zheng, Kahn, Michael, Qabar, Maher, Urban, Jan, Kim, Hwa-Ok and Blaskovich, Mark (2003). Design and synthesis of phosphotyrosine mimetics. Bioorganic & Medicinal Chemistry Letters, 13 (12), 2083-2085. doi: 10.1016/S0960-894X(03)00253-1 |
