2020 Journal Article High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrierHulme, Katina Dee, Yan, Limin, Marshall, Rebecca J., Bloxham, Conor J., Upton, Kyle R., Hasnain, Sumaira Z., Bielefeldt-Ohmann, Helle, Loh, Zhixuan, Ronacher, Katharina, Chew, Keng Yih , Gallo, Linda A. and Short, Kirsty Renfree (2020). High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier. eLife, 9 e56907, 1-20. doi: 10.7554/elife.56907 |
2020 Journal Article Impact of intermediate hyperglycaemia as well as diabetes on immune dysfunction in tuberculosisEckold, Clare, Kumar, Vinod, Weiner Rd, January, Alisjahbana, Bachti, Riza, Anca-Lelia, Ronacher, Katharina, Coronel, Jorge, Kerry-Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Leanie, Stanley, Kim, Ruslami, Rovina, Ioana, Mihai, Ugarte-Gil, Cesar, Walzl, Gerhard, van Crevel, Reinout, Wijmenga, Cisca, Critchley, Julia A., Dockrell, Hazel M., Cliff, Jacqueline M. and for the TANDEM consortium (2020). Impact of intermediate hyperglycaemia as well as diabetes on immune dysfunction in tuberculosis. Clinical Infectious Diseases, 72 (1), 69-78. doi: 10.1093/cid/ciaa751 |
2020 Journal Article Glycemic variability in diabetes increases the severity of influenzaMarshall, Rebecca J., Armart, Pornthida, Hulme, Katina D., Chew, Keng Yih, Brown, Alexandra C., Hansbro, Philip M., Bloxham, Conor J., Flint, Melanie, Ronacher, Katharina, Bielefeldt-Ohmann, Helle, Gallo, Linda A. and Short, Kirsty R. (2020). Glycemic variability in diabetes increases the severity of influenza. mBio, 11 (2) e02841-19. doi: 10.1128/mbio.02841-19 |
2020 Journal Article Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment responseMalherbe, Stephanus T., Chen, Ray Y., Dupont, Patrick, Kant, Ilse, Kriel, Magdalena, Loxton, André G., Smith, Bronwyn, Beltran, Caroline G. G., van Zyl, Susan, McAnda, Shirely, Abrahams, Charmaine, Maasdorp, Elizna, Doruyter, Alex, Via, Laura E., Barry, Clifton E., Alland, David, Griffith-Richards, Stephanie , Ellman, Annare, Peppard, Thomas, Belisle, John, Tromp, Gerard, Ronacher, Katharina, Warwick, James M., Winter, Jill and Walzl, Gerhard (2020). Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response. EJNMMI Research, 10 (1) 8, 8. doi: 10.1186/s13550-020-0591-9 |
2019 Journal Article Time-dependent changes in urinary metabolome before and after intensive phase tuberculosis therapy: A pharmacometabolomics studyCombrink, Monique, du Preez, Ilse, Ronacher, Katharina, Walzl, Gerhard and Loots, Du Toit (2019). Time-dependent changes in urinary metabolome before and after intensive phase tuberculosis therapy: A pharmacometabolomics study. OMICS: A Journal of Integrative Biology, 23 (11) omi.2019.0140, 560-572. doi: 10.1089/omi.2019.0140 |
2019 Journal Article Distinct serum biosignatures are associated with different tuberculosis treatment outcomesRonacher, Katharina, Chegou, Novel N., Kleynhans, Léanie, Djoba Siawaya, Joel F., du Plessis, Nelita, Loxton, André G., Maasdorp, Elizna, Tromp, Gerard, Kidd, Martin, Stanley, Kim, Kriel, Magdalena, Menezes, Angela, Gutschmidt, Andrea, van der Spuy, Gian D., Warren, Robin M., Dietze, Reynaldo, Okwera, Alphonse, Thiel, Bonnie, Belisle, John T., Cliff, Jacqueline M., Boom, W. Henry, Johnson, John L., van Helden, Paul D., Dockrell, Hazel M. and Walzl, Gerhard (2019). Distinct serum biosignatures are associated with different tuberculosis treatment outcomes. Tuberculosis, 118 101859, 101859. doi: 10.1016/j.tube.2019.101859 |
2019 Journal Article Diabetes mellitus among pulmonary tuberculosis patients from four TB-endemic countries: the TANDEM studyUgarte-Gil, Cesar, Alisjahbana, Bachti, Ronacher, Katharina, Riza, Anca Lelia, Koesoemadinata, Raspati C., Malherbe, Stephanus T., Cioboata, Ramona, Llontop, Juan Carlos, Kleynhans, Leanie, Lopez, Sonia, Santoso, Prayudi, Marius, Ciontea, Villaizan, Katerine, Ruslami, Rovina, Walzl, Gerhard, Panduru, Nicolae Mircea, Dockrell, Hazel M., Hill, Philip C., Mc Allister, Susan, Pearson, Fiona, Moore, David A. J, Critchley, Julia A., van Crevel, Reinout and TANDEM Consortium (2019). Diabetes mellitus among pulmonary tuberculosis patients from four TB-endemic countries: the TANDEM study. Clinical Infectious Diseases, 70 (5), 780-788. doi: 10.1093/cid/ciz284 |
2019 Journal Article Point of care HbA1c level for diabetes mellitus management and its accuracy among tuberculosis patients: a study in four countriesHuangfu, P., Laurence, Y. V., Alisjahbana, B., Ugarte-Gil, C., Riza, A-L., Walzl, G., Ruslami, R., Moore, D. A. J., Ioana, M.., McAllister, S., Ronacher, K., Koesoemadinata, R. C., Grint, D., Kerry, S., Coronel, J., Malherbe, S. T., Griffiths, U., Dockrell, H. M., Hill, P. C., van Crevel, R., Pearson, F. and Critchley, J. A. (2019). Point of care HbA1c level for diabetes mellitus management and its accuracy among tuberculosis patients: a study in four countries. International Journal of Tuberculosis and Lung Disease, 23 (3), 283-292. doi: 10.5588/ijtld.18.0359 |
2018 Journal Article Erratum to: A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes (Nature, (2018), 560, 7720, (644-648), 10.1038/s41586-018-0439-x)Roy Chowdhury, Roshni, Vallania, Francesco, Yang, Qianting, Lopez Angel, Cesar Joel, Darboe, Fatoumatta, Penn-Nicholson, Adam, Rozot, Virginie, Nemes, Elisa, Malherbe, Stephanus T., Ronacher, Katharina, Walzl, Gerhard, Hanekom, Willem, Davis, Mark M., Winter, Jill, Chen, Xinchun, Scriba, Thomas J., Khatri, Purvesh and Chien, Yueh-hsiu (2018). Erratum to: A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes (Nature, (2018), 560, 7720, (644-648), 10.1038/s41586-018-0439-x). Nature, 564 (7734), E5-E5. doi: 10.1038/s41586-018-0635-8 |
2018 Journal Article Diabetes screen during tuberculosis contact investigations highlights opportunity for new diabetes diagnosis and reveals metabolic differences between ethnic groupsRestrepo, Blanca I., Kleynhans, Léanie, Salinas, Alejandra B., Abdelbary, Bassent, Tshivhula, Happy, Aguillón-Durán, Genesis P., Kunsevi-Kilola, Carine, Salinas, Gloria, Stanley, Kim, Malherbe, Stephanus T., Maasdorp, Elizna, Garcia-Viveros, Moncerrato, Louw, Ilze, Garcia-Oropesa, Esperanza M., Lopez-Alvarenga, Juan Carlos, Prins, John B., Walzl, Gerhard, Schlesinger, Larry S. and Ronacher, Katharina (2018). Diabetes screen during tuberculosis contact investigations highlights opportunity for new diabetes diagnosis and reveals metabolic differences between ethnic groups. Tuberculosis, 113, 10-18. doi: 10.1016/j.tube.2018.08.007 |
2018 Journal Article 119. Prospective Validation of a 3-Gene Signature for Tuberculosis Diagnosis, Predicting Progression and Evaluating Treatment ResponseWarsinske, Hayley, Rao, Aditya, Moreira, Flora Martinez Figueira, Dos Santos, Paulo Cesar Pereira, Liu, Andrew, Scott, Madeleine, Malherbe, Stephanus, Ronacher, Katharina, Walzl, Gerhard, Winter, Jill, Sweeney, Timothy E, Croda, Julio, Andrews, Jason R and Khatri, Purvesh (2018). 119. Prospective Validation of a 3-Gene Signature for Tuberculosis Diagnosis, Predicting Progression and Evaluating Treatment Response. Open Forum Infectious Diseases, 5 (suppl_1). doi: 10.1093/ofid/ofy209.010 |
2018 Journal Article Assessment of validity of a blood-based 3-gene signature score for progression and diagnosis of tuberculosis, disease severity, and treatment responseWarsinske, Hayley C., Rao, Aditya M., Moreira, Flora M. F., Cesar, Paulo, Liu, Andrew B., Scott, Madeleine, Malherbe, Stephaus T., Ronacher, Katharina, Walzl, Gerhard, Winter, Jill , Sweeney, Timothy E. , Croda, Julio , Andrews, Jason R. and Khatri, Purvesh (2018). Assessment of validity of a blood-based 3-gene signature score for progression and diagnosis of tuberculosis, disease severity, and treatment response. JAMA Network Open, 1 (6), e183779. doi: 10.1001/jamanetworkopen.2018.3779 |
2018 Journal Article IL-22: an underestimated player in natural resistance to tuberculosis?Ronacher, Katharina, Sinha, Roma and Cestari, Michelle (2018). IL-22: an underestimated player in natural resistance to tuberculosis?. Frontiers in Immunology, 9 (SEP) 2209. doi: 10.3389/fimmu.2018.02209 |
2018 Journal Article Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South AfricaGrint, Daniel, Alisjhabana, Bachti, Ugarte-Gil, Cesar, Riza, Anca-Leila, Walzl, Gerhard, Pearson, Fiona, Ruslami, Rovina, Moore, David A. J., Ioana, Mihai, McAllister, Susan, Ronacher, Katharina, Koeseomadinata, Raspati C., Kerry-Barnard, Sarah R., Coronel, Jorge, Malherbe, Stephanus T., Dockrell, Hazel M., Hill, Philip C., Van Crevel, Reinout and Critchley, Julia A. (2018). Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa. Bulletin of the World Health Organization, 96 (11), 738-749. doi: 10.2471/blt.17.206227 |
2018 Journal Article A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomesRoy Chowdhury, Roshni, Vallania, Francesco, Yang, Qiantian, Lopez Angel, Cesar Joel, Darboe, Fatoumatta, Penn-Nicholson, Adam, Rozot, Virginie, Nemes, Elisa, Malherbe, Stephanus T., Ronacher, Katharina, Walzl, Gerhard, Hanekom, Willem, Davis, Mark M., Winter, Jill, Chen, Xinchun, Scriba, Thomas J., Khatri, Purvesh and Chien, Yueh-hsiu (2018). A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes. Nature, 560 (7720), 644-648. doi: 10.1038/s41586-018-0439-x |
2018 Journal Article Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South AfricaSoetedjo, Nanny N. M., McAllister, Susan M., Ugarte-Gil, Cesar, Firanescu, Adela G., Ronacher, Katharina, Alisjahbana, Bachti, Costache, Anca L., Zubiate, Carlos, Malherbe, Stephanus T., Koesoemadinata, Raspati C., Laurence, Yoko V., Pearson, Fiona, Kerry-Barnard, Sarah, Ruslami, Rovina, Moore, David A. J., Ioana, Mihai, Kleynhans, Leanie, Pernama, Hikmat, Hill, Philip C., Mota, Maria, Walzl, Gerhard, Dockrell, Hazel M., Critchley, Julia A. and van Crevel, Reinout (2018). Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South Africa. Tropical Medicine and International Health, 23 (10), 1118-1128. doi: 10.1111/tmi.13137 |
2018 Journal Article A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography imagesMalherbe, Stephanus T., Dupont, Patrick, Kant, Ilse, Ahlers, Petri, Kriel, Magdalena, Loxton, Andre G., Chen, Ray Y., Via, Laura E., Thienemann, Friedrich, Wilkinson, Robert J., Barry, Clifton E., Griffith-Richards, Stephanie, Ellman, Annare, Ronacher, Katharina, Winter, Jill, Walzl, Gerhard and Warwick, James M. (2018). A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images. EJNMMI Research, 8 (1) 55, 55-14. doi: 10.1186/s13550-018-0411-7 |
2018 Journal Article Patients with concurrent tuberculosis and diabetes have a pro-atherogenic plasma lipid profileVrieling, Frank, Ronacher, Katharina, Kleynhans, Léanie, van den Akker, Erik, Walzl, Gerhard, Ottenhoff, Tom H. M. and Joosten, Simone A. (2018). Patients with concurrent tuberculosis and diabetes have a pro-atherogenic plasma lipid profile. EBioMedicine, 32, 192-200. doi: 10.1016/j.ebiom.2018.05.011 |
2017 Journal Article Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cureMalherbe, Stephanus T, Shenai, Shubhada, Ronacher, Katharina, Loxton, Andre G, Dolganov, Gregory, Kriel, Magdalena, Van, Tran, Chen, Ray Y, Warwick, James, Via, Laura E, Song, Taeksun, Lee, Myungsun, Schoolnik, Gary, Tromp, Gerard, Alland, David, Barry, Clifton E, Winter, Jill and Walzl, Gerhard (2017). Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure. Nature Medicine, 23 (12), 1499-1499. doi: 10.1038/nm1217-1499a |
2017 Journal Article Host blood RNA signatures predict the outcome of tuberculosis treatmentThompson, Ethan G., Du, Ying, Malherbe, Stephanus T., Shankar, Smitha, Braun, Jackie, Valvo, Joe, Ronacher, Katharina, Tromp, Gerard, Tabb, David L. , Alland, David , Shenai, Shubhada, Via, Laura E., Warwick, James, Aderem, Alan, Scriba, Thomas J., Winter, Jill, Walzl, Gerhard, Zak, Daniel E. and Catalysis TB-Biomarker Consortium (2017). Host blood RNA signatures predict the outcome of tuberculosis treatment. Tuberculosis, 107, 45-58. doi: 10.1016/j.tube.2017.08.004 |