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2024 Journal Article Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte functionSinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z |
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2024 Journal Article High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virusZhen Wei, Marcus Tong, Hulme, Katina D., Law, Soi Cheng, Noye, Ellesandra, Dorey, Emily S., Chew, Keng Yih, Rowntree, Louise C., van de Sandt, Carolien E., Kedzierska, Katherine, Goeijenbier, Marco, Ronacher, Katharina, Alzaid, Fawaz, Julla, Jean-Baptiste, Riveline, Jean-Pierre, Lineburg, Katie, Smith, Corey, Grant, Emma J., Gras, Stephanie, Gallo, Linda A., Barett, Helen L. and Short, Kirsty R. (2024). High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus. iScience, 27 (11) 111166, 111166. doi: 10.1016/j.isci.2024.111166 |
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2024 Journal Article Characterizing poorly controlled type 2 diabetes using 1H-NMR metabolomicsTheron, Isabella J., Mason, Shayne, van Reenen, Mari, Stander, Zinandré, Kleynhans, Léanie, Ronacher, Katharina and Loots, Du Toit (2024). Characterizing poorly controlled type 2 diabetes using 1H-NMR metabolomics. Metabolomics, 20 (3) 54, 54. doi: 10.1007/s11306-024-02127-w |
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2024 Journal Article Estrogen contributes to sex differences in M2a macrophages during multi‐walled carbon nanotube‐induced respiratory inflammationRay, Jessica L., Postma, Britten, Kendall, Rebekah L., Ngo, Minh Dao, Foo, Cheng Xiang, Saunders, Brett, Ronacher, Katharina, Gowdy, Kymberly M. and Holian, Andrij (2024). Estrogen contributes to sex differences in M2a macrophages during multi‐walled carbon nanotube‐induced respiratory inflammation. The FASEB Journal, 38 (1) e23350, 1-19. doi: 10.1096/fj.202301571rr |
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2024 Journal Article Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitusHulme, Katina D., Tong, Zhen Wei Marcus, Rowntree, Louise C., van de Sandt, Carolien E., Ronacher, Katharina, Grant, Emma J., Dorey, Emily S., Gallo, Linda A., Gras, Stephanie, Kedzierska, Katherine, Barrett, Helen L. and Short, Kirsty R. (2024). Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus. Cellular and Molecular Life Sciences, 81 (1) 35. doi: 10.1007/s00018-023-05010-4 |
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2024 Journal Article Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysisHamada, Yohhei, Quartagno, Matteo, Malik, Farihah, Ntshamane, Keolebogile, Tisler, Anna, Gaikwad, Sanjay, Acuna-Villaorduna, Carlos, Bhavani, Perumal Kannabiran, Alisjahbana, Bachti, Ronacher, Katharina, Apriani, Lika, Becerra, Mercedes, Chu, Alexander L., Creswell, Jacob, Diaz, Gustavo, Ferro, Beatriz E., Galea, Jerome T., Grandjean, Louis, Grewal, Harleen M. S., Gupta, Amita, Jones-López, Edward C., Kleynhans, Léanie, Lecca, Leonid, MacPherson, Peter, Murray, Megan, Marín, Diana, Restrepo, Blanca I., Shivakumar, Shri Vijay Bala Yogendra, Shu, Eileen ... Rangaka, Molebogeng X. (2024). Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis. Tropical Medicine and International Health, 29 (9), 768-780. doi: 10.1111/tmi.14038 |
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2023 Journal Article Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidityEckold, Clare, van Doorn, Cassandra L. R., Ruslami, Rovina, Ronacher, Katharina, Riza, Anca-Lelia, van Veen, Suzanne, Lee, Ji-Sook, Kumar, Vinod, Kerry-Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Leanie, Stanley, Kim, Joosten, Simone A., Critchley, Julia A., Hill, Philip C., van Crevel, Reinout, Wijmenga, Cisca, Haks, Marielle C., Ioana, Mihai, Alisjahbana, Bachti, Walzl, Gerhard, Ottenhoff, Tom H. M., Dockrell, Hazel M., Vianello, Eleonora, Cliff, Jacqueline M. and TANDEM Consortium, (2023). Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity. Clinical and Translational Medicine, 13 (9) e1375, 1-21. doi: 10.1002/ctm2.1375 |
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2023 Journal Article Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidityEckold, Clare, van Doorn, Cassandra L. R., Ruslami, Rovina, Ronacher, Katharina, Riza, Anca‐Lelia, van Veen, Suzanne, Lee, Ji‐Sook, Kumar, Vinod, Kerry‐Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Léanie, Stanley, Kim, Joosten, Simone A., Critchley, Julia A, Hill, Philip C., van Crevel, Reinout, Wijmenga, Cisca, Haks, Mariëlle C., Ioana, Mihai, Alisjahbana, Bachti, Walzl, Gerhard, Ottenhoff, Tom H. M., Dockrell, Hazel M., Vianello, Eleonora and Cliff, Jacqueline M. (2023). Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity. Clinical and Translational Medicine, 13 (9) e1375. doi: 10.1002/ctm2.1375 |
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2023 Journal Article GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infectionFoo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022 |
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2022 Journal Article Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosisMeier, Stuart, Seddon, James A., Maasdorp, Elizna, Kleynhans, Léanie, du Plessis, Nelita, Loxton, Andre G., Malherbe, Stephanus T., Zak, Daniel E., Thompson, Ethan, Duffy, Fergal J., Kaufmann, Stefan H.E., Ottenhoff, Tom H.M., Scriba, Thomas J., Suliman, Sara, Sutherland, Jayne S., Winter, Jill, Kuivaniemi, Helena, Walzl, Gerhard, Tromp, Gerard, Black, Gillian F., van der Spuy, Gian, Stanley, Kim, Kriel, Magdalena, Nene, Nonhlanhla, Roberts, Teri, Gutschmidt, Andrea, Smith, Bronwyn, Chegou, Novel N., Tabb, David ... Warwick, James M. (2022). Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis. PLoS One, 17 (12 ) e0278295, 1-24. doi: 10.1371/journal.pone.0278295 |
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2022 Journal Article Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatmentvan Doorn, Cassandra L. R., Eckold, Clare, Ronacher, Katharina, Ruslami, Rovina, van Veen, Suzanne, Lee, Ji-Sook, Kumar, Vinod, Kerry-Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Léanie, Stanley, Kim, Hill, Philip C., Joosten, Simone A., van Crevel, Reinout, Wijmenga, Cisca, Critchley, Julia A., Walzl, Gerhard, Alisjahbana, Bachti, Haks, Mariëlle C., Dockrell, Hazel M., Ottenhoff, Tom H. M., Vianello, Eleonora, Cliff, Jacqueline M. and on behalf of the TANDEM Consortium (2022). Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment. EBioMedicine, 82 104173, 1-17. doi: 10.1016/j.ebiom.2022.104173 |
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2022 Journal Article A blunted GPR183/oxysterol axis during dysglycemia results in delayed recruitment of macrophages to the lung during Mycobacterium tuberculosis infectionNgo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Foo, Cheng Xiang, Sinha, Roma, Arachige, Buddhika Jayakody, Reed, Sarah, Mandrup-Poulsen, Thomas, Rosenkilde, Mette Marie and Ronacher, Katharina (2022). A blunted GPR183/oxysterol axis during dysglycemia results in delayed recruitment of macrophages to the lung during Mycobacterium tuberculosis infection. The Journal of Infectious Diseases, 225 (12), 2219-2228. doi: 10.1093/infdis/jiac102 |
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2022 Journal Article Interplay Between the Immune and Endocrine Systems in the Lung: Implications for TB SusceptibilityWebber, Tariq, Ronacher, Katharina, Conradie-Smit, Marli and Kleynhans, Léanie (2022). Interplay Between the Immune and Endocrine Systems in the Lung: Implications for TB Susceptibility. Frontiers in immunology, 13 829355. doi: 10.3389/fimmu.2022.829355 |
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2022 Journal Article Oxysterols in the immune response to bacterial and viral infectionsFoo, Cheng Xiang, Bartlett, Stacey and Ronacher, Katharina (2022). Oxysterols in the immune response to bacterial and viral infections. Cells, 11 (2) 201, 201. doi: 10.3390/cells11020201 |
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2021 Journal Article Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. dyslipidemiaNgo, Minh Dao, Bartlett, Stacey and Ronacher, Katharina (2021). Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. dyslipidemia. Microorganisms, 9 (11) 2282, 2282. doi: 10.3390/microorganisms9112282 |
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2021 Journal Article Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is ProtectiveSinha, Roma, Ngo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Keshvari, Sahar, Hasnain, Sumaira Z., Donovan, Meg L., Kling, Jessica C., Blumenthal, Antje, Chen, Chen, Short, Kirsty R. and Ronacher, Katharina (2021). Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective. Frontiers in Cellular and Infection Microbiology, 11 691823, 691823. doi: 10.3389/fcimb.2021.691823 |
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2021 Journal Article Chronological metabolic response to intensive phase TB therapy in patients with cured and failed treatment outcomesOpperman, Monique, Loots, Du Toit, van Reenen, Mari, Ronacher, Katharina, Walzl, Gerhard and du Preez, Ilse (2021). Chronological metabolic response to intensive phase TB therapy in patients with cured and failed treatment outcomes. ACS Infectious Diseases, 7 (6) acsinfecdis.1c00162, 1859-1869. doi: 10.1021/acsinfecdis.1c00162 |
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2021 Journal Article Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment responseCilliers, Karen, Menezes, Angela, Webber, Tariq, Dockrell, Hazel M., Cliff, Jacqueline M., Kleynhans, Léanie, Chegou, Novel N., du Plessis, Nelita, Loxton, André G., Kidd, Martin, Djoba Siawaya, Joel Fleury, Ronacher, Katharina and Walzl, Gerhard (2021). Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment response. Tuberculosis, 128 102082, 102082. doi: 10.1016/j.tube.2021.102082 |
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2021 Journal Article The peripheral blood transcriptome is correlated with PET measures of lung inflammation during successful tuberculosis treatmentOdia, Trust, Malherbe, Stephanus T., Meier, Stuart, Maasdorp, Elizna, Kleynhans, Léanie, du Plessis, Nelita, Loxton, Andre G., Zak, Daniel E., Thompson, Ethan, Duffy, Fergal J., Kuivaniemi, Helena, Ronacher, Katharina, Winter, Jill, Walzl, Gerhard, Tromp, Gerard and Catalysis TB-Biomarker Consortium (2021). The peripheral blood transcriptome is correlated with PET measures of lung inflammation during successful tuberculosis treatment. Frontiers in Immunology, 11 Frontiers Research Foundation. doi: 10.3389/fimmu.2020.596173 |
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2020 Journal Article GPR183 regulates interferons, autophagy, and bacterial growth during Mycobacterium tuberculosis infection and is associated with TB disease severityBartlett, Stacey, Gemiarto, Adrian Tandhyka, Ngo, Minh Dao, Sajiir, Haressh, Hailu, Semira, Sinha, Roma, Foo, Cheng Xiang, Kleynhans, Léanie, Tshivhula, Happy, Webber, Tariq, Bielefeldt-Ohmann, Helle, West, Nicholas P., Hiemstra, Andriette M., MacDonald, Candice E., Christensen, Liv von Voss, Schlesinger, Larry S., Walzl, Gerhard, Rosenkilde, Mette Marie, Mandrup-Poulsen, Thomas and Ronacher, Katharina (2020). GPR183 regulates interferons, autophagy, and bacterial growth during Mycobacterium tuberculosis infection and is associated with TB disease severity. Frontiers in Immunology, 11 601534, 601534. doi: 10.3389/fimmu.2020.601534 |
