Skip to menu Skip to content Skip to footer

2024

Journal Article

Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function

Sinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z

Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function

2024

Journal Article

High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus

Zhen Wei, Marcus Tong, Hulme, Katina D., Law, Soi Cheng, Noye, Ellesandra, Dorey, Emily S., Chew, Keng Yih, Rowntree, Louise C., van de Sandt, Carolien E., Kedzierska, Katherine, Goeijenbier, Marco, Ronacher, Katharina, Alzaid, Fawaz, Julla, Jean-Baptiste, Riveline, Jean-Pierre, Lineburg, Katie, Smith, Corey, Grant, Emma J., Gras, Stephanie, Gallo, Linda A., Barett, Helen L. and Short, Kirsty R. (2024). High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus. iScience, 27 (11) 111166, 111166. doi: 10.1016/j.isci.2024.111166

High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus

2024

Journal Article

Characterizing poorly controlled type 2 diabetes using 1H-NMR metabolomics

Theron, Isabella J., Mason, Shayne, van Reenen, Mari, Stander, Zinandré, Kleynhans, Léanie, Ronacher, Katharina and Loots, Du Toit (2024). Characterizing poorly controlled type 2 diabetes using 1H-NMR metabolomics. Metabolomics, 20 (3) 54, 54. doi: 10.1007/s11306-024-02127-w

Characterizing poorly controlled type 2 diabetes using 1H-NMR metabolomics

2024

Journal Article

Estrogen contributes to sex differences in M2a macrophages during multi‐walled carbon nanotube‐induced respiratory inflammation

Ray, Jessica L., Postma, Britten, Kendall, Rebekah L., Ngo, Minh Dao, Foo, Cheng Xiang, Saunders, Brett, Ronacher, Katharina, Gowdy, Kymberly M. and Holian, Andrij (2024). Estrogen contributes to sex differences in M2a macrophages during multi‐walled carbon nanotube‐induced respiratory inflammation. The FASEB Journal, 38 (1) e23350, 1-19. doi: 10.1096/fj.202301571rr

Estrogen contributes to sex differences in M2a macrophages during multi‐walled carbon nanotube‐induced respiratory inflammation

2024

Journal Article

Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus

Hulme, Katina D., Tong, Zhen Wei Marcus, Rowntree, Louise C., van de Sandt, Carolien E., Ronacher, Katharina, Grant, Emma J., Dorey, Emily S., Gallo, Linda A., Gras, Stephanie, Kedzierska, Katherine, Barrett, Helen L. and Short, Kirsty R. (2024). Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus. Cellular and Molecular Life Sciences, 81 (1) 35. doi: 10.1007/s00018-023-05010-4

Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus

2024

Book Chapter

Oxysterols in infectious diseases

Foo, Cheng X., Fessler, Michael B. and Ronacher, Katharina (2024). Oxysterols in infectious diseases. Implication of oxysterols and phytosterols in aging and human diseases. (pp. 125-147) edited by Gérard Lizard. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-43883-7_7

Oxysterols in infectious diseases

2024

Journal Article

Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis

Hamada, Yohhei, Quartagno, Matteo, Malik, Farihah, Ntshamane, Keolebogile, Tisler, Anna, Gaikwad, Sanjay, Acuna-Villaorduna, Carlos, Bhavani, Perumal Kannabiran, Alisjahbana, Bachti, Ronacher, Katharina, Apriani, Lika, Becerra, Mercedes, Chu, Alexander L., Creswell, Jacob, Diaz, Gustavo, Ferro, Beatriz E., Galea, Jerome T., Grandjean, Louis, Grewal, Harleen M. S., Gupta, Amita, Jones-López, Edward C., Kleynhans, Léanie, Lecca, Leonid, MacPherson, Peter, Murray, Megan, Marín, Diana, Restrepo, Blanca I., Shivakumar, Shri Vijay Bala Yogendra, Shu, Eileen ... Rangaka, Molebogeng X. (2024). Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis. Tropical Medicine and International Health, 29 (9), 768-780. doi: 10.1111/tmi.14038

Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis

2023

Journal Article

Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity

Eckold, Clare, van Doorn, Cassandra L. R., Ruslami, Rovina, Ronacher, Katharina, Riza, Anca-Lelia, van Veen, Suzanne, Lee, Ji-Sook, Kumar, Vinod, Kerry-Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Leanie, Stanley, Kim, Joosten, Simone A., Critchley, Julia A., Hill, Philip C., van Crevel, Reinout, Wijmenga, Cisca, Haks, Marielle C., Ioana, Mihai, Alisjahbana, Bachti, Walzl, Gerhard, Ottenhoff, Tom H. M., Dockrell, Hazel M., Vianello, Eleonora, Cliff, Jacqueline M. and TANDEM Consortium, (2023). Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity. Clinical and Translational Medicine, 13 (9) e1375, 1-21. doi: 10.1002/ctm2.1375

Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity

2023

Journal Article

Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity

Eckold, Clare, van Doorn, Cassandra L. R., Ruslami, Rovina, Ronacher, Katharina, Riza, Anca‐Lelia, van Veen, Suzanne, Lee, Ji‐Sook, Kumar, Vinod, Kerry‐Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Léanie, Stanley, Kim, Joosten, Simone A., Critchley, Julia A, Hill, Philip C., van Crevel, Reinout, Wijmenga, Cisca, Haks, Mariëlle C., Ioana, Mihai, Alisjahbana, Bachti, Walzl, Gerhard, Ottenhoff, Tom H. M., Dockrell, Hazel M., Vianello, Eleonora and Cliff, Jacqueline M. (2023). Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity. Clinical and Translational Medicine, 13 (9) e1375. doi: 10.1002/ctm2.1375

Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity

2023

Journal Article

GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection

Foo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022

GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection

2022

Journal Article

Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis

Meier, Stuart, Seddon, James A., Maasdorp, Elizna, Kleynhans, Léanie, du Plessis, Nelita, Loxton, Andre G., Malherbe, Stephanus T., Zak, Daniel E., Thompson, Ethan, Duffy, Fergal J., Kaufmann, Stefan H.E., Ottenhoff, Tom H.M., Scriba, Thomas J., Suliman, Sara, Sutherland, Jayne S., Winter, Jill, Kuivaniemi, Helena, Walzl, Gerhard, Tromp, Gerard, Black, Gillian F., van der Spuy, Gian, Stanley, Kim, Kriel, Magdalena, Nene, Nonhlanhla, Roberts, Teri, Gutschmidt, Andrea, Smith, Bronwyn, Chegou, Novel N., Tabb, David ... Warwick, James M. (2022). Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis. PLoS One, 17 (12 ) e0278295, 1-24. doi: 10.1371/journal.pone.0278295

Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis

2022

Journal Article

Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment

van Doorn, Cassandra L. R., Eckold, Clare, Ronacher, Katharina, Ruslami, Rovina, van Veen, Suzanne, Lee, Ji-Sook, Kumar, Vinod, Kerry-Barnard, Sarah, Malherbe, Stephanus T., Kleynhans, Léanie, Stanley, Kim, Hill, Philip C., Joosten, Simone A., van Crevel, Reinout, Wijmenga, Cisca, Critchley, Julia A., Walzl, Gerhard, Alisjahbana, Bachti, Haks, Mariëlle C., Dockrell, Hazel M., Ottenhoff, Tom H. M., Vianello, Eleonora, Cliff, Jacqueline M. and on behalf of the TANDEM Consortium (2022). Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment. EBioMedicine, 82 104173, 1-17. doi: 10.1016/j.ebiom.2022.104173

Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment

2022

Journal Article

A blunted GPR183/oxysterol axis during dysglycemia results in delayed recruitment of macrophages to the lung during Mycobacterium tuberculosis infection

Ngo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Foo, Cheng Xiang, Sinha, Roma, Arachige, Buddhika Jayakody, Reed, Sarah, Mandrup-Poulsen, Thomas, Rosenkilde, Mette Marie and Ronacher, Katharina (2022). A blunted GPR183/oxysterol axis during dysglycemia results in delayed recruitment of macrophages to the lung during Mycobacterium tuberculosis infection. The Journal of Infectious Diseases, 225 (12), 2219-2228. doi: 10.1093/infdis/jiac102

A blunted GPR183/oxysterol axis during dysglycemia results in delayed recruitment of macrophages to the lung during Mycobacterium tuberculosis infection

2022

Journal Article

Interplay Between the Immune and Endocrine Systems in the Lung: Implications for TB Susceptibility

Webber, Tariq, Ronacher, Katharina, Conradie-Smit, Marli and Kleynhans, Léanie (2022). Interplay Between the Immune and Endocrine Systems in the Lung: Implications for TB Susceptibility. Frontiers in immunology, 13 829355. doi: 10.3389/fimmu.2022.829355

Interplay Between the Immune and Endocrine Systems in the Lung: Implications for TB Susceptibility

2022

Journal Article

Oxysterols in the immune response to bacterial and viral infections

Foo, Cheng Xiang, Bartlett, Stacey and Ronacher, Katharina (2022). Oxysterols in the immune response to bacterial and viral infections. Cells, 11 (2) 201, 201. doi: 10.3390/cells11020201

Oxysterols in the immune response to bacterial and viral infections

2021

Journal Article

Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. dyslipidemia

Ngo, Minh Dao, Bartlett, Stacey and Ronacher, Katharina (2021). Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. dyslipidemia. Microorganisms, 9 (11) 2282, 2282. doi: 10.3390/microorganisms9112282

Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. dyslipidemia

2021

Journal Article

Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective

Sinha, Roma, Ngo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Keshvari, Sahar, Hasnain, Sumaira Z., Donovan, Meg L., Kling, Jessica C., Blumenthal, Antje, Chen, Chen, Short, Kirsty R. and Ronacher, Katharina (2021). Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective. Frontiers in Cellular and Infection Microbiology, 11 691823, 691823. doi: 10.3389/fcimb.2021.691823

Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective

2021

Journal Article

Chronological metabolic response to intensive phase TB therapy in patients with cured and failed treatment outcomes

Opperman, Monique, Loots, Du Toit, van Reenen, Mari, Ronacher, Katharina, Walzl, Gerhard and du Preez, Ilse (2021). Chronological metabolic response to intensive phase TB therapy in patients with cured and failed treatment outcomes. ACS Infectious Diseases, 7 (6) acsinfecdis.1c00162, 1859-1869. doi: 10.1021/acsinfecdis.1c00162

Chronological metabolic response to intensive phase TB therapy in patients with cured and failed treatment outcomes

2021

Journal Article

Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment response

Cilliers, Karen, Menezes, Angela, Webber, Tariq, Dockrell, Hazel M., Cliff, Jacqueline M., Kleynhans, Léanie, Chegou, Novel N., du Plessis, Nelita, Loxton, André G., Kidd, Martin, Djoba Siawaya, Joel Fleury, Ronacher, Katharina and Walzl, Gerhard (2021). Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment response. Tuberculosis, 128 102082, 102082. doi: 10.1016/j.tube.2021.102082

Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment response

2021

Journal Article

The peripheral blood transcriptome is correlated with PET measures of lung inflammation during successful tuberculosis treatment

Odia, Trust, Malherbe, Stephanus T., Meier, Stuart, Maasdorp, Elizna, Kleynhans, Léanie, du Plessis, Nelita, Loxton, Andre G., Zak, Daniel E., Thompson, Ethan, Duffy, Fergal J., Kuivaniemi, Helena, Ronacher, Katharina, Winter, Jill, Walzl, Gerhard, Tromp, Gerard and Catalysis TB-Biomarker Consortium (2021). The peripheral blood transcriptome is correlated with PET measures of lung inflammation during successful tuberculosis treatment. Frontiers in Immunology, 11 Frontiers Research Foundation. doi: 10.3389/fimmu.2020.596173

The peripheral blood transcriptome is correlated with PET measures of lung inflammation during successful tuberculosis treatment