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2018

Journal Article

A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images

Malherbe, Stephanus T., Dupont, Patrick, Kant, Ilse, Ahlers, Petri, Kriel, Magdalena, Loxton, Andre G., Chen, Ray Y., Via, Laura E., Thienemann, Friedrich, Wilkinson, Robert J., Barry, Clifton E., Griffith-Richards, Stephanie, Ellman, Annare, Ronacher, Katharina, Winter, Jill, Walzl, Gerhard and Warwick, James M. (2018). A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images. EJNMMI Research, 8 (1) 55, 55-14. doi: 10.1186/s13550-018-0411-7

A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images

2018

Journal Article

Patients with concurrent tuberculosis and diabetes have a pro-atherogenic plasma lipid profile

Vrieling, Frank, Ronacher, Katharina, Kleynhans, Léanie, van den Akker, Erik, Walzl, Gerhard, Ottenhoff, Tom H. M. and Joosten, Simone A. (2018). Patients with concurrent tuberculosis and diabetes have a pro-atherogenic plasma lipid profile. EBioMedicine, 32, 192-200. doi: 10.1016/j.ebiom.2018.05.011

Patients with concurrent tuberculosis and diabetes have a pro-atherogenic plasma lipid profile

2017

Journal Article

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

Malherbe, Stephanus T, Shenai, Shubhada, Ronacher, Katharina, Loxton, Andre G, Dolganov, Gregory, Kriel, Magdalena, Van, Tran, Chen, Ray Y, Warwick, James, Via, Laura E, Song, Taeksun, Lee, Myungsun, Schoolnik, Gary, Tromp, Gerard, Alland, David, Barry, Clifton E, Winter, Jill and Walzl, Gerhard (2017). Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure. Nature Medicine, 23 (12), 1499-1499. doi: 10.1038/nm1217-1499a

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

2017

Journal Article

Host blood RNA signatures predict the outcome of tuberculosis treatment

Thompson, Ethan G., Du, Ying, Malherbe, Stephanus T., Shankar, Smitha, Braun, Jackie, Valvo, Joe, Ronacher, Katharina, Tromp, Gerard, Tabb, David L. , Alland, David , Shenai, Shubhada, Via, Laura E., Warwick, James, Aderem, Alan, Scriba, Thomas J., Winter, Jill, Walzl, Gerhard, Zak, Daniel E. and Catalysis TB-Biomarker Consortium (2017). Host blood RNA signatures predict the outcome of tuberculosis treatment. Tuberculosis, 107, 45-58. doi: 10.1016/j.tube.2017.08.004

Host blood RNA signatures predict the outcome of tuberculosis treatment

2017

Journal Article

Predicting tuberculosis treatment outcome using metabolomics

Luies, Laneke, Reenen, Mari van, Ronacher, Katharina, Walzl, Gerhard and Loots, Du Toit (2017). Predicting tuberculosis treatment outcome using metabolomics. Biomarkers in Medicine, 11 (12), 1057-1067. doi: 10.2217/bmm-2017-0133

Predicting tuberculosis treatment outcome using metabolomics

2017

Journal Article

Urinary metabolite markers characterising tuberculosis treatment failure

Luies, Laneke, Mienie, Japie, Motshwane, Christinah, Ronacher, Katharina, Walzl, Gerhard and Loots, Du Toit  (2017). Urinary metabolite markers characterising tuberculosis treatment failure. Metabolomics, 13 (10) 124. doi: 10.1007/s11306-017-1261-4

Urinary metabolite markers characterising tuberculosis treatment failure

2017

Journal Article

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management

Critchley, Julia A., Restrepo, Blanca I., Ronacher, Katharina, Kapur, Anil, Bremer, Andrew A., Schlesinger, Larry S., Basaraba, Randall, Kornfeld, Hardy and van Crevel, Reinout (2017). Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management. Chest, 152 (1), 165-173. doi: 10.1016/j.chest.2017.04.155

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management

2017

Journal Article

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 2: underlying biological mechanisms

Ronacher, Katharina, van Crevel, Reinout, Critchley, Julia, Bremer, Andrew A., Schlesinger, Larry S., Kapur, Anil, Basaraba, Randall, Kornfeld, Hardy and Restrepo, Blanca I. (2017). Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 2: underlying biological mechanisms. Chest, 152 (1), 174-180. doi: 10.1016/j.chest.2017.02.032

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 2: underlying biological mechanisms

2017

Journal Article

Changes in host immune-endocrine relationships during tuberculosis treatment in patients with cured and failed treatment outcomes

Kleynhans, Leanie, Ruzive, Sheena, Ehlers, Lizaan, Thiart, Lani, Chegou, Novel N., Conradie, Magda, Kriel, Magdalena, Stanley, Kim, van der Spuy, Gian D., Kidd, Martin, van Helden, Paul D., Walzl, Gerhard and Ronacher, Katharina (2017). Changes in host immune-endocrine relationships during tuberculosis treatment in patients with cured and failed treatment outcomes. Frontiers in Immunology, 8 (JUN) 690, 690. doi: 10.3389/fimmu.2017.00690

Changes in host immune-endocrine relationships during tuberculosis treatment in patients with cured and failed treatment outcomes

2017

Journal Article

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

Malherbe, Stephanus T, Shenai, Shubhada, Ronacher, Katharina, Loxton, Andre G, Dolganov, Gregory, Kriel, Magdalena, Van, Tran, Chen, Ray Y, Warwick, James, Via, Laura E, Song, Taeksun, Lee, Myungsun, Schoolnik, Gary, Tromp, Gerard, Alland, David, Barry, Clifton E, Winter, Jill, Walzl, Gerhard and Catalysis TB–Biomarker Consortium (2017). Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure. Nature Medicine, 23 (4), 526-526. doi: 10.1038/nm0417-526a

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

2017

Journal Article

High-throughput identification of DNA-encoded IgG ligands that distinguish active and latent Mycobacterium tuberculosis infections

Mendes, Kimberly R., Malone, Marie Lynne, Ndungu, John Maina, Suponitsky-Kroyter, Irena, Cavett, Valerie J., McEnaney, Patrick J., MacConnell, Andrew B., Doran, Todd M., Ronacher, Katharina, Stanley, Kim, Utset, Ofelia, Walzl, Gerhard, Paegel, Brian M. and Kodadek, Thomas (2017). High-throughput identification of DNA-encoded IgG ligands that distinguish active and latent Mycobacterium tuberculosis infections. ACS Chemical Biology, 12 (1), 234-243. doi: 10.1021/acschembio.6b00855

High-throughput identification of DNA-encoded IgG ligands that distinguish active and latent Mycobacterium tuberculosis infections

2016

Journal Article

Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

Malherbe, Stephanus T., Shenai, Shubhada, Ronacher, Katharina, Loxton, Andre G., Dolganov, Gregory, Kriel, Magdalena, Van, Tran, Chen, Ray Y., Warwick, James, Via, Laura E., Song, Taeksun, Lee, Myungsun, Schoolnik, Gary, Tromp, Gerard, Alland, David, Barry, Clifton E, Winter, Jill, Walzl, Gerhard, Catalysis TB–Biomarker Consortium, Lucas, L., Spuy, G.V.D., Stanley, K., Theart, L., Smith, B., Burger, N., Beltran, C.G.G., Maasdorp, E., Ellmann, A., Choi, H. ... Griffith-Richards, S. (2016). Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure. Nature Medicine, 22 (10), 1094-1100. doi: 10.1038/nm.4177

Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

2016

Journal Article

Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA

van Rensburg, Ilana C., Wagman, Chandre, Stanley, Kim, Beltran, Caroline, Ronacher, Katharina, Walzl, Gerhard and Loxton, Andre G. (2016). Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA. Oncotarget, 8 (2), 2037-2043. doi: 10.18632/oncotarget.12184

Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA

2016

Journal Article

Bacterial loads measured by the Xpert MTB/RIF assay as markers of culture conversion and biological cure in pulmonary TB

Shenai, Shubhada, Ronacher, Katharina, Malherbe, Stefanus, Stanley, Kim, Kriel, Magdalena, Winter, Jill, Peppard, Thomas, Barry, Charles E., Wang, Jing, Dodd, Lori E., Via, Laura E., Barry, Clifton E. 3rd, Walzl, Gerhard and Alland, David (2016). Bacterial loads measured by the Xpert MTB/RIF assay as markers of culture conversion and biological cure in pulmonary TB. PLoS One, 11 (8) e0160062, e0160062.1-e0160062.13. doi: 10.1371/journal.pone.0160062

Bacterial loads measured by the Xpert MTB/RIF assay as markers of culture conversion and biological cure in pulmonary TB

2016

Journal Article

Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy

Honeyborne, Isobella, McHugh, Timothy D., Kuittinen, Iitu, Cichonska, Anna, Evangelopoulos, Dimitrios, Ronacher, Katharina, van Helden, Paul D., Gillespie, Stephen H., Fernandez-Reyes, Delmiro, Walzl, Gerhard, Rousu, Juho, Butcher, Philip D. and Waddell, Simon J. (2016). Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy. BMC Medicine, 14 (1) 68, 68.1-68.13. doi: 10.1186/s12916-016-0609-3

Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy

2016

Journal Article

The functional response of B cells to antigenic stimulation: a preliminary report of latent tuberculosis

Du Plessis, Willem J., Kleynhans, Léanie, Du Plessis, Nelita, Stanley, Kim, Malherbe, Stephanus T., Maasdorp, Elizna, Ronacher, Katharina , Chegou, Novel N., Walzl, Gerhard and Loxton, Andre G. (2016). The functional response of B cells to antigenic stimulation: a preliminary report of latent tuberculosis. PLoS One, 11 (4) e0152710, e0152710.1-e0152710.16. doi: 10.1371/journal.pone.0152710

The functional response of B cells to antigenic stimulation: a preliminary report of latent tuberculosis

2016

Journal Article

Excessive cytolytic responses predict tuberculosis relapse after apparently successful treatment

Cliff, Jacqueline M., Cho, Jang-Eun, Lee, Ji-Sook, Ronacher, Katharina, King, Elizabeth C., van Helden, Paul, Walzl, Gerhard and Dockrell, Hazel M. (2016). Excessive cytolytic responses predict tuberculosis relapse after apparently successful treatment. Journal of Infectious Diseases, 213 (3), 485-495. doi: 10.1093/infdis/jiv447

Excessive cytolytic responses predict tuberculosis relapse after apparently successful treatment

2015

Journal Article

Relationship between female genital tract infections, mucosal interleukin-17 production and local T helper type 17 cells

Masson, Lindi, Salkinder, Amy L. , Olivier, Abraham Jacobus, Mckinnon, Lyle R. , Gamieldien, Hoyam, Mlisana, Koleka, Scriba, Thomas J. , Lewis, David A. , Little, Francesca, Jaspan, Heather B. , Ronacher, Katharina, Denny, Lynette, Abdool Karim, Salim S. and Passmore, Jo-Ann S. (2015). Relationship between female genital tract infections, mucosal interleukin-17 production and local T helper type 17 cells. Immunology, 146 (4), 557-567. doi: 10.1111/imm.12527

Relationship between female genital tract infections, mucosal interleukin-17 production and local T helper type 17 cells

2015

Journal Article

Genital Inflammation and the Risk of HIV Acquisition in Women

Masson L., Passmore J.-A.S., Liebenberg L.J., Werner L., Baxter C., Arnold K.B., Williamson C., Little F., Mansoor L.E., Naranbhai V., Lauffenburger D.A., Ronacher K., Walzl G., Garrett N.J., Williams B.L., Couto-Rodriguez M., Hornig M., Lipkin W.I., Grobler A., Abdool Karim Q. and Abdool Karim S.S. (2015). Genital Inflammation and the Risk of HIV Acquisition in Women. Clinical Infectious Diseases, 61 (2), 260-269. doi: 10.1093/cid/civ298

Genital Inflammation and the Risk of HIV Acquisition in Women

2015

Journal Article

Clinical immunology and multiplex biomarkers of human tuberculosis

Walzl, Gerhard, Haks, Mariëlle C., Joosten, Simone A., Kleynhans, Léanie, Ronacher, Katharina and Ottenhoff, Tom H. M. (2015). Clinical immunology and multiplex biomarkers of human tuberculosis. Cold Spring Harbor Perspectives in Medicine, 5 (4) a018515. doi: 10.1101/cshperspect.a018515

Clinical immunology and multiplex biomarkers of human tuberculosis