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2018

Book Chapter

Nonuniform sampling in biomolecular NMR

Miljenovic, Tomas Marko, Jia, Xinying and Mobli, Mehdi (2018). Nonuniform sampling in biomolecular NMR. Modern magnetic resonance. (pp. 2035-2054) edited by Graham A. Webb. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-28388-3_118

Nonuniform sampling in biomolecular NMR

2017

Journal Article

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling

Hughes, Mark M., Lavrencic, Peter, Coll, Rebecca C., Ve, Thomas, Ryan, Dylan G., Williams, Niamh C., Menon, Deepthi, Mansell, Ashley, Board, Philip G., Mobli, Mehdi, Kobe, Bostjan and O'Neill, Luke A. J. (2017). Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling. Proceedings of the National Academy of Sciences, 114 (32), E6480-E6489. doi: 10.1073/pnas.1701868114

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling

2017

Journal Article

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

Ve, Thomas, Vajjhala, Parimala, Hedger, Andrew, Croll, Tristan, DiMaio, Frank, Horsefield, Shane, Yu, Xiong, Lavrencic, Peter, Hassan, Zahid, Morgan, Garry P., Mansell, Ashley, Mobli, Mehdi, O'Carroll, Ailis, Chauvin, Brieuc, Gambin, Yann, Sierecki, Emma, Landsberg, Michael J., Stacey, Katryn, Egelman, Edward H. and Kobe, Bostjan (2017). Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling. Nature Structural and Molecular Biology, 24 (9), 743-751. doi: 10.1038/nsmb.3444

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

2017

Journal Article

Two proteins for the price of one: structural studies of the dual-destiny protein preproalbumin with sunflower trypsin inhibitor-1

Franke, Bastian, James, Amy M., Mobli, Mehdi, Colgrave, Michelle L., Mylne, Joshua S. and Rosengren, K. Johan (2017). Two proteins for the price of one: structural studies of the dual-destiny protein preproalbumin with sunflower trypsin inhibitor-1. The Journal of Biological Chemistry, 292 (30), 12398-12411. doi: 10.1074/jbc.M117.776955

Two proteins for the price of one: structural studies of the dual-destiny protein preproalbumin with sunflower trypsin inhibitor-1

2017

Journal Article

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.

Wingerd, Joshua S., Mozar, Christine A., Ussing, Christine A., Murali, Swetha S., Chin, Yanni K. -Y., Cristofori-Armstrong, Ben, Durek, Thomas, Gilchrist, John, Vaughan, Christopher W., Bosmans, Frank, Adams, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Christie, Macdonald J. and Rash, Lachlan D. (2017). The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.. Scientific Reports, 7 (1) 974, 974. doi: 10.1038/s41598-017-01129-0

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.

2017

Journal Article

Modulation of ion channels by cysteine-rich peptides: from sequence to structure

Mobli, Mehdi, Undheim, Eivind A.B. and Rash, Lachlan D. (2017). Modulation of ion channels by cysteine-rich peptides: from sequence to structure. Advances in Pharmacology, 79, 199-223. doi: 10.1016/bs.apha.2017.03.001

Modulation of ion channels by cysteine-rich peptides: from sequence to structure

2017

Journal Article

The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant

Rahnama, Sassan, Deuis, Jennifer R., Cardoso, Fernanda C., Ramanujam, Venkatraman, Lewis, Richard J., Rash, Lachlan D., King, Glenn F., Vetter, Irina and Mobli, Mehdi (2017). The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant. PLoS One, 12 (3) e0173551, e0173551. doi: 10.1371/journal.pone.0173551

The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant

2017

Journal Article

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a

Chassagnon, Irene R., McCarthy, Claudia A., Chin, Yanni K.-Y., Pineda, Sandy S., Keramidas, Angelo, Mobli, Mehdi, Pham, Vi, De Silva, T. Michael, Lynch, Joseph W., Widdop, Robert E., Rash, Lachlan D. and King, Glenn F. (2017). Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a. Proceedings from the National Academy of Sciences of the United States of America, 114 (14), 3750-3755. doi: 10.1073/pnas.1614728114

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a

2017

Journal Article

A non-uniform sampling approach enables studies of dilute and unstable proteins

Miljenović, Tomas, Jia, Xinying, Lavrencic, Peter, Kobe, Bostjan and Mobli, Mehdi (2017). A non-uniform sampling approach enables studies of dilute and unstable proteins. Journal of Biomolecular NMR, 68 (2), 1-9. doi: 10.1007/s10858-017-0091-z

A non-uniform sampling approach enables studies of dilute and unstable proteins

2017

Journal Article

Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responses

Wan, Jingjing, Mobli, Mehdi, Brust, Andreas, Muttenthaler, Markus, Andersson, Asa, Ragnarsson, Lotten, Castro, Joel, Vetter, Irina, Huang, Johnny X., Nilsson, Mathias, Brierley, Stuart M., Cooper, Matthew A., Lewis, Richard J. and Alewood, Paul F. (2017). Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responses. Australian Journal of Chemistry, 70 (2), 162-171. doi: 10.1071/CH16407

Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responses

2017

Book Chapter

Fast NMR data acquisition: beyond the Fourier transform: Preface

Mobli, Mehdi and Hoch, Jeffrey C. (2017). Fast NMR data acquisition: beyond the Fourier transform: Preface. Fast NMR data acquisition: beyond the Fourier transform. (pp. VIII-X) edited by Mehdi Mobli and Jeffrey C. Hoch. Cambridge, United Kingdom: Royal Society of Chemistry.

Fast NMR data acquisition: beyond the Fourier transform: Preface

2017

Book Chapter

Maximum entropy reconstruction

Mobli, Mehdi, Stern, Alan S. and Hoch, Jeffrey C. (2017). Maximum entropy reconstruction. Fast NMR data acquisition: beyond the Fourier transform. (pp. 252-266) edited by Mehdi Mobli and Jeffrey C. Hoch. Cambridge, United Kingdom: Royal Society of Chemistry.

Maximum entropy reconstruction

2017

Book

Fast NMR data acquisition: beyond the Fourier transform

Mehdi Mobli and Jeffrey C. Hoch eds. (2017). Fast NMR data acquisition: beyond the Fourier transform. New Developments in NMR, Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781782628361

Fast NMR data acquisition: beyond the Fourier transform

2016

Journal Article

NaV1.7 as a pain target – from gene to pharmacology

Vetter, Irina, Deuis, Jennifer, Mueller, Alexander, Israel, Mathilde R., Hana Starobova, Zhang, Alan, Rash, Lachlan D. and Mobli, Mehdi (2016). NaV1.7 as a pain target – from gene to pharmacology. Pharmacology and Therapeutics, 172, 73-100. doi: 10.1016/j.pharmthera.2016.11.015

NaV1.7 as a pain target – from gene to pharmacology

2016

Journal Article

The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins

Casey, Lachlan W., Lavrencic, Peter, Bentham, Adam R., Cesari, Stella, Ericsson, Daniel J., Croll, Tristan, Turk, Dušan, Anderson, Peter A., Mark, Alan E., Dodds, Peter N., Mobli, Mehdi, Kobe, Bostjan and Williams, Simon J. (2016). The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins. Proceedings of the National Academy of Sciences, 113 (45), 12856-12861. doi: 10.1073/pnas.1609922113

The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins

2016

Journal Article

Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data

Mohanty, Biswaranjan, Williams, Martin L., Doak, Bradley C., Vazirani, Mansha, Ilyichova, Olga, Wang, Geqing, Bermel, Wolfgang, Simpson, Jamie S., Chalmers, David K., King, Glenn F., Mobli, Mehdi and Scanlon, Martin J. (2016). Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data. Journal of Biomolecular NMR, 66 (3), 195-208. doi: 10.1007/s10858-016-0067-4

Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data

2016

Journal Article

Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels

Lau, Carus H.Y., King, Glenn F and Mobli, Mehdi (2016). Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels. Scientific Reports, 6 (1) 34333, 34333. doi: 10.1038/srep34333

Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels

2016

Journal Article

Correction: Sparse sampling methods in multidimensional NMR

Mobli, Mehdi, Maciejewski, Mark W, Schuyler, Adam D, Stern, Alan S and Hoch, Jeffrey C (2016). Correction: Sparse sampling methods in multidimensional NMR. Physical Chemistry Chemical Physics, 18 (28), 19482-19482. doi: 10.1039/c6cp90157c

Correction: Sparse sampling methods in multidimensional NMR

2016

Journal Article

Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides

Undheim, Eivind A., Mobli, Mehdi and King, Glenn F. (2016). Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides. Bioessays, 38 (6), 539-548. doi: 10.1002/bies.201500165

Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides

2016

Journal Article

Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8

Deuis, Jennifer R, Dekan, Zoltan, Inserra, Marco C., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Craik, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Schroeder, Christina I., Henriques, Sónia Troeira and Vetter, Irina (2016). Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8. Journal of Biological Chemistry, 291 (22), 11829-11842. doi: 10.1074/jbc.M116.721662

Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8