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2016

Journal Article

Inhibition of the norepinephrine transporter by χ-conotoxin dendrimers

Wan, Jingjing, Brust, Andreas, Bhola, Rebecca F., Jha, Prerna, Mobli, Mehdi, Lewis, Richard J., Christie, Macdonald J. and Alewood, Paul F. (2016). Inhibition of the norepinephrine transporter by χ-conotoxin dendrimers. Journal of Peptide Science, 22 (5), 280-289. doi: 10.1002/psc.2857

Inhibition of the norepinephrine transporter by χ-conotoxin dendrimers

2016

Conference Publication

Rational design and synthesis of a novel membrane binding NaV1.8 selective inhibitor with in vivo activity in pain models

Schroeder, Christina I., Deuis, Jennifer, Henriques, Sonia Troeria, Dekan, Zoltan, Inserra, Marco, Mobli, Mehdi and Vetter, Irina (2016). Rational design and synthesis of a novel membrane binding NaV1.8 selective inhibitor with in vivo activity in pain models. 60th Annual Meeting of the Biophysical Society, Los Angeles, CA, United States, 27 Feb - 2 Mar 2016. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2015.11.247

Rational design and synthesis of a novel membrane binding NaV1.8 selective inhibitor with in vivo activity in pain models

2016

Conference Publication

Structural Features of An Unusual Sun-Flower Proalbumin Protein That Gives Rise to a Small Cyclic Peptide and a Seed Storage Protein

Franke, B., James, A., Mobli, M., Mylne, J. S. and Rosengren, K. J. (2016). Structural Features of An Unusual Sun-Flower Proalbumin Protein That Gives Rise to a Small Cyclic Peptide and a Seed Storage Protein. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. HOBOKEN: Wiley.

Structural Features of An Unusual Sun-Flower Proalbumin Protein That Gives Rise to a Small Cyclic Peptide and a Seed Storage Protein

2015

Journal Article

Rational engineering defines a molecular switch that is essential for activity of spider-venom peptides against the analgesics target na(v)1.7

Klint, Julie K., Chin, Yanni K. -Y. and Mobli, Mehdi (2015). Rational engineering defines a molecular switch that is essential for activity of spider-venom peptides against the analgesics target na(v)1.7. Molecular Pharmacology, 88 (6), 1002-1010. doi: 10.1124/mol.115.100784

Rational engineering defines a molecular switch that is essential for activity of spider-venom peptides against the analgesics target na(v)1.7

2015

Journal Article

Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a

Saez, Natalie J., Deplazes, Evelyne, Cristofori-Armstrong, Ben, Chassagnon, Irene R., Lin, Xiaozhen, Mobli, Mehdi, Mark, Alan E., Rash, Lachlan D. and King, Glenn F. (2015). Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a. British Journal of Pharmacology, 172 (20), 4985-4995. doi: 10.1111/bph.13267

Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a

2015

Journal Article

Weaponization of a hormone: convergent recruitment of hyperglycemic hormone into the venom of arthropod predators

Undheim, Eivind A. B., Grimm, Lena L., Low, Chek -Fong, Morgenstern, David, Herzig, Volker, Zobel-Thropp, Pamela, Pineda, Sandy Steffany, Habib, Rosaline, Dziemborowicz, Slawomir, Fry, Bryan G., Nicholson, Graham M., Binford, Greta J., Mobli, Mehdi and King, Glenn F. (2015). Weaponization of a hormone: convergent recruitment of hyperglycemic hormone into the venom of arthropod predators. Structure, 23 (7) 3184, 1283-1292. doi: 10.1016/j.str.2015.05.003

Weaponization of a hormone: convergent recruitment of hyperglycemic hormone into the venom of arthropod predators

2015

Journal Article

Reducing seed dependent variability of non-uniformly sampled multidimensional NMR data

Mobli, Mehdi (2015). Reducing seed dependent variability of non-uniformly sampled multidimensional NMR data. Journal of Magnetic Resonance, 256, 60-69. doi: 10.1016/j.jmr.2015.04.003

Reducing seed dependent variability of non-uniformly sampled multidimensional NMR data

2015

Journal Article

Solution structure of the RNA-binding cold shock domain of the Chlamydomonas reinhardtii NAB1 protein and insights into RNA recognition

Sawyer, Anne L., Landsberg, Michael J., Ross, Ian L., Kruse, Olaf, Mobli, Mehdi and Hankamer, Ben (2015). Solution structure of the RNA-binding cold shock domain of the Chlamydomonas reinhardtii NAB1 protein and insights into RNA recognition. Biochemical Journal, 469 (1), 97-106. doi: 10.1042/BJ20150217

Solution structure of the RNA-binding cold shock domain of the Chlamydomonas reinhardtii NAB1 protein and insights into RNA recognition

2015

Journal Article

Backbone and side chain NMR assignments of Geobacillus stearothermophilus ZapA allow identification of residues that mediate the interaction of ZapA with FtsZ

Nogueira, Maria Luiza C., Sforca, Mauricio Luis, Chin, Yanni K. -Y., Mobli, Mehdi, Handler, Aaron, Gorbatyuk, Vitaliy Y., Robson, Scott A., King, Glenn F., Gueiros-Filho, Frederico J. and de Mattos Zeri, Ana Carolina (2015). Backbone and side chain NMR assignments of Geobacillus stearothermophilus ZapA allow identification of residues that mediate the interaction of ZapA with FtsZ. Biomolecular NMR Assignments, 9 (2), 387-391. doi: 10.1007/s12104-015-9615-1

Backbone and side chain NMR assignments of Geobacillus stearothermophilus ZapA allow identification of residues that mediate the interaction of ZapA with FtsZ

2015

Journal Article

Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach

Klint, Julie K., Smith, Jennifer J., Vetter, Irina, Rupasinghe, Darshani B., Er, Sing Yan, Senff, Sebastian, Herzig, Volker, Mobli, Mehdi, Lewis, Richard J., Bosmans, Frank and King, Glenn F. (2015). Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach. British Journal of Pharmacology, 172 (10), 2445-2458. doi: 10.1111/bph.13081

Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach

2015

Journal Article

RNA polymerase-induced remodelling of NusA produces a pause enhancement complex

Ma, Cong, Mobli, Mehdi, Yang, Xiao, Keller, Andrew N., King, Glenn F. and Lewis, Peter J. (2015). RNA polymerase-induced remodelling of NusA produces a pause enhancement complex. Nucleic Acids Research, 43 (5), 2829-2840. doi: 10.1093/nar/gkv108

RNA polymerase-induced remodelling of NusA produces a pause enhancement complex

2015

Journal Article

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop

Bende, Niraj S., Dziemborowicz, Slawomir, Herzig, Volker, Ramanujam, Venkatraman, Brown, Geoffrey W., Bosmans, Frank, Nicholson, Graham M., King, Glenn F. and Mobli, Mehdi (2015). The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop. FEBS Journal, 282 (5), 904-920. doi: 10.1111/febs.13189

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop

2015

Journal Article

Erratum to "Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR" [Prog. Nucl. Magn. Reson. Spectrosc. 83 (2014) 21-41]

Mobli, Mehdi and Hoch, Jeffrey C. (2015). Erratum to "Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR" [Prog. Nucl. Magn. Reson. Spectrosc. 83 (2014) 21-41]. Progress in Nuclear Magnetic Resonance Spectroscopy, 86-87, 80-80. doi: 10.1016/j.pnmrs.2015.02.001

Erratum to "Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR" [Prog. Nucl. Magn. Reson. Spectrosc. 83 (2014) 21-41]

2015

Journal Article

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors

Wan, Jingjing, Huang, Johnny X., Vetter, Irina, Mobli, Mehdi, Lawson, Joshua, Tae, Han-Shen, Abraham, Nikita, Paul, Blessy, Cooper, Matthew A., Adams, David J., Lewis, Richard J. and Alewood, Paul F. (2015). α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society, 137 (9), 3209-3212. doi: 10.1021/jacs.5b00244

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors

2015

Book Chapter

Research methods

Fry, B. G., Undheim, E. A. B., Jackson, T. N. W., Georgieva, D., Vetter, I., Calvete, J. J., Schieb, H., Cribb, B. W., Yang, D. C., Daly, N. L., Manchadi, M. L. Roy, Gutierrez, J. M., Roelants, K., Lomonte, B., Nicholson, G. M., Dziemborowicz, S., Lavergne, V., Ragnarsson, L., Rash, L. D., Mobli, M., Hodgson, W. C., Casewell, N. R., Nouwens, A., Wagstaff, S. C., Ali, S. A., Whitehead, D. L., Herzig, V., Monagle, P., Kurniawan, N. D. ... Sunagar, K. (2015). Research methods. Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. (pp. 153-214) New York, NY, United States: Oxford University Press.

Research methods

2015

Conference Publication

Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker

Rahnama, S., Lachlan, R., Cardoso, F. C., Smith, J., Deuis, J., Vetter, I., King, G. F. and Mobli, M. (2015). Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker. The 40th Lorne Conference on Protein Structure and Function, Lorne VIC, Australia, 8-12 February 2015.

Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker

2015

Conference Publication

Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design

Schroeder, Christina, Henriques, Sonia, Mobli, Mehdi, Chaousis, Stephanie, Walsh, Phillip, Thongyoo, Panumart and Craik, David (2015). Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design. 29th Annual Symposium of the Protein Society, Barcelona Spain, Jul 22-25, 2015. Hoboken, United States: Wiley-Blackwell Publishing. doi: 10.1002/pro.2823

Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design

2015

Book Chapter

The Structural Universe of Disulfide-Rich Venom Peptides

Lavergne, Vincent, Alewood, Paul F., Mobli, Mehdi and King, Glenn F. (2015). The Structural Universe of Disulfide-Rich Venom Peptides. Venoms to Drugs : Venom as a Source for the Development of Human Therapeutics. (pp. 37-79) edited by King, Glenn F.. London, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00037

The Structural Universe of Disulfide-Rich Venom Peptides

2014

Journal Article

Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR

Mobli, Mehdi and Hoch, Jeffrey C. (2014). Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR. Progress in Nuclear Magnetic Resonance Spectroscopy, 83, 21-41. doi: 10.1016/j.pnmrs.2014.09.002

Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR

2014

Journal Article

Molecular insights into the interaction between plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide

Wang, Geqing, MacRaild, Christopher A., Mohanty, Biswaranjan, Mobli, Mehdi, Cowieson, Nathan P., Anders, Robin F., Simpson, Jamie S., McGowan, Sheena, Norton, Raymond S. and Scanlon, Martin J. (2014). Molecular insights into the interaction between plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide. PLoS One, 9 (10) e109674, 1-12. doi: 10.1371/journal.pone.0109674

Molecular insights into the interaction between plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide