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2014

Journal Article

Non-uniform sampling in EPR-optimizing data acquisition for HYSCORE spectroscopy

Nakka, K. K., Tesiram, Y. A., Brereton, I. M., Mobli, M. and Harmer, J. R. (2014). Non-uniform sampling in EPR-optimizing data acquisition for HYSCORE spectroscopy. Physical Chemistry Chemical Physics, 16 (31), 16378-16382. doi: 10.1039/c4cp02172j

Non-uniform sampling in EPR-optimizing data acquisition for HYSCORE spectroscopy

2014

Journal Article

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

Bende, Niraj S., Dziemborowicz, Sławomir, Mobli, Mehdi, Herzig, Volker, Gilchrist, John, Wagner, Jordan, Nicholson, Graham M., King, Glenn F and Bosmans, Frank (2014). A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nature Communications, 5 (1) 4350, 4350. doi: 10.1038/ncomms5350

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

2014

Journal Article

Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels

Klint, Julie K., Berecki, Géza, Durek, Thomas, Mobli, Mehdi, Knapp, Oliver, King, Glenn F., Adams, David J., Alewood, Paul F. and Rash, Lachlan D. (2014). Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels. Biochemical Pharmacology, 89 (2), 276-286. doi: 10.1016/j.bcp.2014.02.008

Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels

2014

Journal Article

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6

Bobby, Romel, Robustelli, Paul, Kralicek, Andrew V., Mobli, Mehdi, King, Glenn F., Grotzinger, Joachim and Dingley, Andrew J. (2014). Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6. FEBS Journal, 281 (10), 2471-2483. doi: 10.1111/febs.12800

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6

2014

Journal Article

Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl

Dekan, Zoltan, Mobli, Mehdi, Pennington, Michael W., Fung, Eileen, Nemeth, Elizabeta and Alewood, Paul F. (2014). Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl. Angewandte Chemie International Edition, 53 (11), 2931-2934. doi: 10.1002/anie.201310103

Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl

2014

Journal Article

Nonuniform sampling and maximum entropy reconstruction in multidimensional NMR

Hoch, Jeffrey C., Maciejewski, Mark W., Mobli, Mehdi, Schuyler, Adam D. and Stern, Alan S. (2014). Nonuniform sampling and maximum entropy reconstruction in multidimensional NMR. Accounts of Chemical Research, 47 (2), 708-717. doi: 10.1021/ar400244v

Nonuniform sampling and maximum entropy reconstruction in multidimensional NMR

2014

Journal Article

A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain

Gui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric and Nitabach, Michael N. (2014). A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain. Current Biology, 24 (5), 473-483. doi: 10.1016/j.cub.2014.01.013

A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain

2014

Journal Article

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie, 126 (4), 1035-1038. doi: 10.1002/ange.201308898

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

2014

Journal Article

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2. Angewandte Chemie International Edition, 53 (4), 1017-1020. doi: 10.1002/anie.201308898

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

2014

Journal Article

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J. and Mulvenna, Jason (2014). Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10), 1-26. doi: 10.1074/jbc.M113.531558

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

2014

Journal Article

Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores

Jensen, Jonas E., Cristofori-Armstrong, Ben, Anangi, Raveendra, Rosengren, K. Johan, Lau, Carus H. Y., Mobli, Mehdi, Brust, Andreas, Alewood, Paul F., King, Glenn F. and Rash, Lachlan D. (2014). Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores. Journal of Medicinal Chemistry, 57 (21), 9195-9203. doi: 10.1021/jm501400p

Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores

2014

Journal Article

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

Dantas De Araujo, Aline, Mobli, Mehdi, Castro, Joel, Harrington, Andrea M., Vetter, Irina, Dekan, Zoltan, Muttenthale, Markus, Wan, JingJing, Lewis, Richard J., King, Glenn F., Brierley, Stuart M. and Alewood, Paul F. (2014). Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications, 5 (1) 3165, 3165.1-3165.12. doi: 10.1038/ncomms4165

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

2014

Journal Article

Measuring interactions of FERM domain-containing sorting nexin proteins with endosomal lipids and cargo molecules

Ghai, Rajesh, Mobli, Mehdi and Collins, Brett M. (2014). Measuring interactions of FERM domain-containing sorting nexin proteins with endosomal lipids and cargo molecules. Methods in Enzymology, 534, 331-349. doi: 10.1016/B978-0-12-397926-1.00019-6

Measuring interactions of FERM domain-containing sorting nexin proteins with endosomal lipids and cargo molecules

2013

Journal Article

Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?

Dantas De Araujo, Aline, Herzig, Volker, Windley, Monique J., Dziemborowicz, Slawomir, Mobli, Mehdi, Nicholson, Graham M., Alewood, Paul F. and King, Glenn F. (2013). Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?. Antioxidants and Redox Signaling, 19 (16), 1976-1980. doi: 10.1089/ars.2013.5365

Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?

2013

Journal Article

Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter

Brust, Andreas, Wang, Ching-I. A., Daly, Norelle L., Kennerly, Joe, Sadeghi, Mahsa, Christie, Macdonald J., Lewis, Richard J., Mobli, Mehdi and Alewood, Paul F. (2013). Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter. Angewandte Chemie (International Edition), 52 (46), 12020-12023. doi: 10.1002/anie.201304660

Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter

2013

Journal Article

Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula

Hardy, Margaret C., Daly, Norelle L., Mobli, Mehdi, Morales, Rodrigo A. V. and King, Glenn F. (2013). Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula. PLoS ONE, 8 (9), e73136.1-e73136.12. doi: 10.1371/journal.pone.0073136

Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula

2013

Journal Article

Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein

Smirnova, Ekaterina, Shanbhag, Riya, Kurabi, Arwa, Mobli, Mehdi, Kwan, Jamie J. and Donaldson, Logan W. (2013). Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein. PLoS ONE, 8 (6) e65605, e65605.1-e65605.8. doi: 10.1371/journal.pone.0065605

Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein

2013

Journal Article

Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli

Klint, Julie K., Senff, Sebastian, Saez, Natalie J., Seshadri, Radha, Lau, Ho Yee, Bende, Nira J., Undheim, Eivind A. B., Rash, Lachlan D., Mobli, Mehdi and King, Glenn F. (2013). Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli. PLoS One, 8 (5) e63865, e63865.1-e63865.12. doi: 10.1371/journal.pone.0063865

Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli

2013

Other Outputs

Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula (Table S1)

Hardy, Margaret, Daly, Norelle L., Mobli, Mehdi , Morales, Rodrigo and King, Glenn F (2013). Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula (Table S1). Figshare. (Dataset) doi: 10.1371/journal.pone.0073136.s001

Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula (Table S1)

2013

Journal Article

The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels

Bende, Niraj S., Kang, Eunji, Herzig, Volker, Bosmans, Frank, Nicholson, Graham M., Mobli, Mehdi and King, Glenn F. (2013). The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels. Biochemical Pharmacology, 85 (10), 1542-1554. doi: 10.1016/j.bcp.2013.02.030

The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels