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2015

Journal Article

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop

Bende, Niraj S., Dziemborowicz, Slawomir, Herzig, Volker, Ramanujam, Venkatraman, Brown, Geoffrey W., Bosmans, Frank, Nicholson, Graham M., King, Glenn F. and Mobli, Mehdi (2015). The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop. FEBS Journal, 282 (5), 904-920. doi: 10.1111/febs.13189

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop

2015

Book Chapter

The Structural Universe of Disulfide-Rich Venom Peptides

Lavergne, Vincent, Alewood, Paul F., Mobli, Mehdi and King, Glenn F. (2015). The Structural Universe of Disulfide-Rich Venom Peptides. Venoms to Drugs : Venom as a Source for the Development of Human Therapeutics. (pp. 37-79) edited by King, Glenn F.. London, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00037

The Structural Universe of Disulfide-Rich Venom Peptides

2015

Journal Article

Erratum to "Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR" [Prog. Nucl. Magn. Reson. Spectrosc. 83 (2014) 21-41]

Mobli, Mehdi and Hoch, Jeffrey C. (2015). Erratum to "Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR" [Prog. Nucl. Magn. Reson. Spectrosc. 83 (2014) 21-41]. Progress in Nuclear Magnetic Resonance Spectroscopy, 86-87, 80-80. doi: 10.1016/j.pnmrs.2015.02.001

Erratum to "Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR" [Prog. Nucl. Magn. Reson. Spectrosc. 83 (2014) 21-41]

2015

Journal Article

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors

Wan, Jingjing, Huang, Johnny X., Vetter, Irina, Mobli, Mehdi, Lawson, Joshua, Tae, Han-Shen, Abraham, Nikita, Paul, Blessy, Cooper, Matthew A., Adams, David J., Lewis, Richard J. and Alewood, Paul F. (2015). α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society, 137 (9), 3209-3212. doi: 10.1021/jacs.5b00244

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors

2015

Book Chapter

Research methods

Fry, B. G., Undheim, E. A. B., Jackson, T. N. W., Georgieva, D., Vetter, I., Calvete, J. J., Schieb, H., Cribb, B. W., Yang, D. C., Daly, N. L., Manchadi, M. L. Roy, Gutierrez, J. M., Roelants, K., Lomonte, B., Nicholson, G. M., Dziemborowicz, S., Lavergne, V., Ragnarsson, L., Rash, L. D., Mobli, M., Hodgson, W. C., Casewell, N. R., Nouwens, A., Wagstaff, S. C., Ali, S. A., Whitehead, D. L., Herzig, V., Monagle, P., Kurniawan, N. D. ... Sunagar, K. (2015). Research methods. Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. (pp. 153-214) New York, NY, United States: Oxford University Press.

Research methods

2015

Conference Publication

Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker

Rahnama, S., Lachlan, R., Cardoso, F. C., Smith, J., Deuis, J., Vetter, I., King, G. F. and Mobli, M. (2015). Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker. The 40th Lorne Conference on Protein Structure and Function, Lorne VIC, Australia, 8-12 February 2015.

Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker

2015

Conference Publication

Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design

Schroeder, Christina, Henriques, Sonia, Mobli, Mehdi, Chaousis, Stephanie, Walsh, Phillip, Thongyoo, Panumart and Craik, David (2015). Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design. 29th Annual Symposium of the Protein Society, Barcelona Spain, Jul 22-25, 2015. Hoboken, United States: Wiley-Blackwell Publishing. doi: 10.1002/pro.2823

Delineating toxin:lipid:ion channel interactions for rationally sodium channel inhibitors design

2014

Journal Article

Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR

Mobli, Mehdi and Hoch, Jeffrey C. (2014). Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR. Progress in Nuclear Magnetic Resonance Spectroscopy, 83, 21-41. doi: 10.1016/j.pnmrs.2014.09.002

Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR

2014

Journal Article

Molecular insights into the interaction between plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide

Wang, Geqing, MacRaild, Christopher A., Mohanty, Biswaranjan, Mobli, Mehdi, Cowieson, Nathan P., Anders, Robin F., Simpson, Jamie S., McGowan, Sheena, Norton, Raymond S. and Scanlon, Martin J. (2014). Molecular insights into the interaction between plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide. PLoS One, 9 (10) e109674, 1-12. doi: 10.1371/journal.pone.0109674

Molecular insights into the interaction between plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide

2014

Journal Article

Non-uniform sampling in EPR-optimizing data acquisition for HYSCORE spectroscopy

Nakka, K. K., Tesiram, Y. A., Brereton, I. M., Mobli, M. and Harmer, J. R. (2014). Non-uniform sampling in EPR-optimizing data acquisition for HYSCORE spectroscopy. Physical Chemistry Chemical Physics, 16 (31), 16378-16382. doi: 10.1039/c4cp02172j

Non-uniform sampling in EPR-optimizing data acquisition for HYSCORE spectroscopy

2014

Journal Article

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

Bende, Niraj S., Dziemborowicz, Sławomir, Mobli, Mehdi, Herzig, Volker, Gilchrist, John, Wagner, Jordan, Nicholson, Graham M., King, Glenn F and Bosmans, Frank (2014). A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nature Communications, 5 (1) 4350, 4350. doi: 10.1038/ncomms5350

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

2014

Journal Article

Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels

Klint, Julie K., Berecki, Géza, Durek, Thomas, Mobli, Mehdi, Knapp, Oliver, King, Glenn F., Adams, David J., Alewood, Paul F. and Rash, Lachlan D. (2014). Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels. Biochemical Pharmacology, 89 (2), 276-286. doi: 10.1016/j.bcp.2014.02.008

Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels

2014

Journal Article

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6

Bobby, Romel, Robustelli, Paul, Kralicek, Andrew V., Mobli, Mehdi, King, Glenn F., Grotzinger, Joachim and Dingley, Andrew J. (2014). Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6. FEBS Journal, 281 (10), 2471-2483. doi: 10.1111/febs.12800

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6

2014

Journal Article

Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl

Dekan, Zoltan, Mobli, Mehdi, Pennington, Michael W., Fung, Eileen, Nemeth, Elizabeta and Alewood, Paul F. (2014). Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl. Angewandte Chemie International Edition, 53 (11), 2931-2934. doi: 10.1002/anie.201310103

Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl

2014

Journal Article

Nonuniform sampling and maximum entropy reconstruction in multidimensional NMR

Hoch, Jeffrey C., Maciejewski, Mark W., Mobli, Mehdi, Schuyler, Adam D. and Stern, Alan S. (2014). Nonuniform sampling and maximum entropy reconstruction in multidimensional NMR. Accounts of Chemical Research, 47 (2), 708-717. doi: 10.1021/ar400244v

Nonuniform sampling and maximum entropy reconstruction in multidimensional NMR

2014

Journal Article

A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain

Gui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric and Nitabach, Michael N. (2014). A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain. Current Biology, 24 (5), 473-483. doi: 10.1016/j.cub.2014.01.013

A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain

2014

Journal Article

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2. Angewandte Chemie International Edition, 53 (4), 1017-1020. doi: 10.1002/anie.201308898

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

2014

Journal Article

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie, 126 (4), 1035-1038. doi: 10.1002/ange.201308898

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

2014

Journal Article

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J. and Mulvenna, Jason (2014). Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10), 1-26. doi: 10.1074/jbc.M113.531558

Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni

2014

Journal Article

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

Dantas De Araujo, Aline, Mobli, Mehdi, Castro, Joel, Harrington, Andrea M., Vetter, Irina, Dekan, Zoltan, Muttenthale, Markus, Wan, JingJing, Lewis, Richard J., King, Glenn F., Brierley, Stuart M. and Alewood, Paul F. (2014). Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications, 5 (1) 3165, 3165.1-3165.12. doi: 10.1038/ncomms4165

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain