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2020 Journal Article An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteriaElliott, Alysha G., Huang, Johnny X., Neve, Søren, Zuegg, Johannes, Edwards, Ingrid A., Cain, Amy K., Boinett, Christine J., Barquist, Lars, Lundberg, Carina Vingsbo, Steen, Jason, Butler, Mark S., Mobli, Mehdi, Porter, Kaela M., Blaskovich, Mark A. T., Lociuro, Sergio, Strandh, Magnus and Cooper, Matthew A. (2020). An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria. Nature Communications, 11 (1) 3184, 3184. doi: 10.1038/s41467-020-16950-x |
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2020 Journal Article Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding genePineda, Sandy S., Chin, Yanni K.-Y., Undheim, Eivind A. B., Senff, Sebastian, Mobli, Mehdi, Dauly, Claire, Escoubas, Pierre, Nicholson, Graham M., Kaas, Quentin, Guo, Shaodong, Herzig, Volker, Mattick, John S. and King, Glenn F. (2020). Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene. Proceedings of the National Academy of Sciences, 117 (21) A41, 201914536-11408. doi: 10.1073/pnas.1914536117 |
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2020 Journal Article Mapping the molecular surface of the analgesic NaV1.7-selective peptide Pn3a reveals residues essential for membrane and channel interactionsMueller, Alexander, Dekan, Zoltan, Kaas, Quentin, Agwa, Akello J., Starobova, Hana, Alewood, Paul F., Schroeder, Christina I., Mobli, Mehdi, Deuis, Jennifer R. and Vetter, Irina (2020). Mapping the molecular surface of the analgesic NaV1.7-selective peptide Pn3a reveals residues essential for membrane and channel interactions. ACS Pharmacology and Translational Science. doi: 10.1021/acsptsci.0c00002 |
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2020 Journal Article Residual dipolar couplings for resolving cysteine bridges in disulfide-rich peptidesRamanujam, Venkatraman, Shen, Yang, Ying, Jinfa and Mobli, Mehdi (2020). Residual dipolar couplings for resolving cysteine bridges in disulfide-rich peptides. Frontiers in Chemistry, 7 889, 1-13. doi: 10.3389/fchem.2019.00889 |
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2019 Journal Article Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosaElnahriry, Khaled A., Wai, Dorothy C.C., Krishnarjuna, Bankala, Badawy, Noha N., Chittoor, Balasubramanyam, MacRaild, Christopher A., Williams-Noonan, Billy J., Surm, Joachim M., Chalmers, David K., Zhang, Alan H., Peigneur, Steve, Mobli, Mehdi, Tytgat, Jan, Prentis, Peter and Norton, Raymond S. (2019). Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa. Toxicon, 168, 104-112. doi: 10.1016/j.toxicon.2019.07.002 |
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2019 Journal Article A new vector coupling ligation-independent cloning with sortase a fusion for efficient cloning and one-step purification of tag-free recombinant proteinsJia, Xinying, Crawford, Theo, Zhang, Alan H. and Mobli, Mehdi (2019). A new vector coupling ligation-independent cloning with sortase a fusion for efficient cloning and one-step purification of tag-free recombinant proteins. Protein Expression and Purification, 161, 1-7. doi: 10.1016/j.pep.2019.04.004 |
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2019 Journal Article Elucidating the lipid binding properties of membrane-active peptides using cyclised nanodiscsZhang, Alan H., Edwards, Ingrid A., Mishra, Biswa P., Sharma, Gagan, Healy, Michael D., Elliott, Alysha, Blaskovich, Mark A. T., Cooper, Matthew A., Collins, Brett M., Jia, Xinying and Mobli, Mehdi (2019). Elucidating the lipid binding properties of membrane-active peptides using cyclised nanodiscs. Frontiers in Chemistry, 7 (MAR) 238, 238. doi: 10.3389/fchem.2019.00238 |
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2019 Journal Article Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificitiesChandra, Mintu, Chin, Yanni K.-Y., Mas, Caroline, Feathers, J. Ryan, Paul, Blessy, Datta, Sanchari, Chen, Kai-En, Jia, Xinying, Yang, Zhe, Norwood, Suzanne J., Mohanty, Biswaranjan, Bugarcic, Andrea, Teasdale, Rohan D., Henne, W. Mike, Mobli, Mehdi and Collins, Brett M. (2019). Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nature Communications, 10 (1) 1528, 1528. doi: 10.1038/s41467-019-09355-y |
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2019 Journal Article Optimizing the transformation of HYSCORE data using the maximum entropy algorithmMotygullina, Alina E., Mobli, Mehdi and Harmer, Jeffrey R. (2019). Optimizing the transformation of HYSCORE data using the maximum entropy algorithm. Journal of Magnetic Resonance, 301, 30-39. doi: 10.1016/j.jmr.2019.02.002 |
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2019 Journal Article Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell CarcinomaCrawford, Theo, Fletcher, Nicholas, Veitch, Margaret, Gonzalez Cruz, Jazmina L., Pett, Nicola, Brereton, Ian, Wells, James W., Mobli, Mehdi and Tesiram, Yasvir (2019). Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma. Frontiers in Medicine, 6 (FEB) 22, 22. doi: 10.3389/fmed.2019.00022 |
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2019 Journal Article Video with impact: access to the world's Magnetic-Resonance experts for the scientific-education communityKwan, Ann H., Mobli, Mehdi, Schirra, Horst J., Wilson, Jennifer C. and Jones, Oliver A. H. (2019). Video with impact: access to the world's Magnetic-Resonance experts for the scientific-education community. Journal of Chemical Education, 96 (1), 159-164. doi: 10.1021/acs.jchemed.8b00523 |
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2019 Journal Article Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeuticsBrinson, Robert G., Marino, John P., Delaglio, Frank, Arbogast, Luke W., Evans, Ryan M., Kearsley, Anthony, Gingras, Geneviève, Ghasriani, Houman, Aubin, Yves, Pierens, Gregory K., Jia, Xinying, Mobli, Mehdi, Grant, Hamish G., Keizer, David W., Schweimer, Kristian, Ståhle, Jonas, Widmalm, Göran, Zartler, Edward R., Lawrence, Chad W., Reardon, Patrick N., Cort, John R., Xu, Ping, Ni, Feng, Yanaka, Saeko, Kato, Koichi, Parnham, Stuart R., Tsao, Desiree, Blomgren, Andreas, Rundlöf, Torgny ... Wikström, Mats (2019). Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics. mAbs, 11 (1), 94-105. doi: 10.1080/19420862.2018.1544454 |
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2019 Journal Article Framework for and evaluation of bursts in random sampling of multidimensional NMR experimentsMobli, M. and Miljenovic, Tomas M. (2019). Framework for and evaluation of bursts in random sampling of multidimensional NMR experiments. Journal of Magnetic Resonance, 300, 103-113. doi: 10.1016/j.jmr.2019.01.014 |
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2018 Journal Article Secreted cysteine-rich repeat proteins "SCREPs": a novel multi-domain architectureMaxwell, Michael, Undheim, Eivind A. B. and Mobli, Mehdi (2018). Secreted cysteine-rich repeat proteins "SCREPs": a novel multi-domain architecture. Frontiers in Pharmacology, 9 (NOV) 01333, 1333. doi: 10.3389/fphar.2018.01333 |
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2018 Journal Article Efficient biosynthesis of heterodimeric C3-aryl pyrroloindoline alkaloidsTian, Wenya, Sun, Chenghai, Zheng, Mei, Harmer, Jeffrey R., Yu, Mingjia, Zhang, Yanan, Peng, Haidong, Zhu, Dongqing, Deng, Zixin, Chen, Shi-Lu, Mobli, Mehdi, Jia, Xinying and Qu, Xudong (2018). Efficient biosynthesis of heterodimeric C3-aryl pyrroloindoline alkaloids. Nature Communications, 9 (1) 4428, 4428. doi: 10.1038/s41467-018-06528-z |
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2018 Journal Article Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal PeptidesHerzig, Volker, de Araujo, Aline, Greenwood, Kathryn, Chin, Yanni, Windley, Monique, Chong, Youmie, Muttenthaler, Markus, Mobli, Mehdi, Audsley, Neil, Nicholson, Graham, Alewood, Paul and King, Glenn (2018). Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines, 6 (3) 90, 90. doi: 10.3390/biomedicines6030090 |
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2018 Journal Article Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature deathRichards, Kay L., Milligan, Carol J., Richardson, Robert J., Jancovski, Nikola, Grunnet, Morten, Jacobson, Laura H., Undheim, Eivind A. B., Mobli, Mehdi, Chow, Chun Yuen, Herzig, Volker, Csoti, Agota, Panyi, Gyorgy, Reid, Christopher A., King, Glenn F. and Petrou, Steven (2018). Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death. Proceedings of the National Academy of Sciences, 115 (34), 201804764-E8085. doi: 10.1073/pnas.1804764115 |
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2018 Journal Article Corrigendum to: Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter (Angewandte Chemie International Edition, (2013), 52, 46, (12020-12023), 10.1002/anie.201304660)Brust, Andreas, Wang, Ching-I. A., Daly, Norelle L., Kennerly, Joe, Sadeghi, Mahsa, Christie, Macdonald J., Lewis, Richard J., Mobli, Mehdi and Alewood, Paul F. (2018). Corrigendum to: Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter (Angewandte Chemie International Edition, (2013), 52, 46, (12020-12023), 10.1002/anie.201304660). Angewandte Chemie - International Edition, 57 (19), 5203-5203. doi: 10.1002/anie.201803138 |
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2018 Journal Article A complicated complex: ion channels, voltage sensing, cell membranes and peptide inhibitorsZhang, Alan H., Sharma, Gagan, Undheim, Eivind A. B., Jia, Xinying and Mobli, Mehdi (2018). A complicated complex: ion channels, voltage sensing, cell membranes and peptide inhibitors. Neuroscience Letters, 679, 35-47. doi: 10.1016/j.neulet.2018.04.030 |
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2018 Journal Article Structural insights into the mechanism of inhibition of AHAS by herbicidesLonhienne, Thierry, Garcia, Mario D., Pierens, Gregory, Mobli, Mehdi, Nouwens, Amanda and Guddat, Luke W. (2018). Structural insights into the mechanism of inhibition of AHAS by herbicides. Proceedings of the National Academy of Sciences of the United States of America, 115 (9), E1945-E1954. doi: 10.1073/pnas.1714392115 |
