2021 Journal Article Testing the correlates of consciousness in brain organoids: how do we know and what do we do?Ankeny, Rachel A. and Wolvetang, Ernst (2021). Testing the correlates of consciousness in brain organoids: how do we know and what do we do?. The American Journal of Bioethics, 21 (1), 51-53. doi: 10.1080/15265161.2020.1845869 |
2020 Journal Article Self-organizing 3D human choroid plexus-ventricle-cortical organoidsShaker, Mohammed R. , Cooper-White, Justin and Wolvetang, Ernst J. (2020). Self-organizing 3D human choroid plexus-ventricle-cortical organoids. |
2020 Journal Article Direct comparison of four hematopoietic differentiation methods from human induced pluripotent stem cellsTursky, Melinda L., Loi, To Ha, Artuz, Crisbel M., Alateeq, Suad, Wolvetang, Ernst J., Tao, Helen, Ma, David D. and Molloy, Timothy J. (2020). Direct comparison of four hematopoietic differentiation methods from human induced pluripotent stem cells. Stem Cell Reports, 15 (3), 735-748. doi: 10.1016/j.stemcr.2020.07.009 |
2020 Journal Article Telomere transcription in AgeingAguado, Julio, d’Adda di Fagagna, Fabrizio and Wolvetang, Ernst (2020). Telomere transcription in Ageing. Ageing Research Reviews, 62 101115, 101115. doi: 10.1016/j.arr.2020.101115 |
2020 Conference Publication Thyroid hormone and TGF-? inhibition drive functional maturation of human pluripotent stem cell-derived hepatocytesWithey, Sarah, Gerrard, Dave, Leeson, Hannah, Atkinson-Dell, Rebecca, Harrison, Sean, Baxter, Melissa, Al-Anbaki, Ali, Hanley, Karen Piper, Wolvetang, Ernst and Hanley., Neil (2020). Thyroid hormone and TGF-? inhibition drive functional maturation of human pluripotent stem cell-derived hepatocytes. EASL: The Digital International Liver Congress, Online, 27-29 August 2020. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s0168-8278(20)31000-x |
2020 Conference Publication Zika Virus sfRNA plays an essential role in the infection of insects and mammalsSlonchak, Andrii, Hugo, Leon E., Freney, Morgan, Amarilla, Alberto A., Hall-Mendelin, Sonja, Yan, Kexin, Torres, Francisco, Setoh, Yin Xiang, Peng, Nias, Chaggar, Harman K., Hurk, Andrew Van Den, Wolvetang, Ernst, Suhrbier, Andreas, Devine, Gregor J. and Khromykh, Alexander A. (2020). Zika Virus sfRNA plays an essential role in the infection of insects and mammals. Viruses 2020—Novel Concepts in Virology, Barcelona, Spain, 5–7 February 2020. Basel, Switzerland: MDPI. doi: 10.3390/proceedings2020050112 |
2020 Journal Article Use of human induced pluripotent stem cells and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy for cystinosisHollywood, Jennifer A., Przepiorski, Aneta, D'Souza, Randall F., Sreebhavan, Sreevalsan, Wolvetang, Ernst J., Harrison, Patrick T., Davidson, Alan J. and Holm, Teresa M. (2020). Use of human induced pluripotent stem cells and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy for cystinosis. Journal of the American Society of Nephrology , 31 (5), 962-982. doi: 10.1681/ASN.2019070712 |
2020 Journal Article Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responsesOvchinnikov, Dmitry A., Withey, Sarah L., Leeson, Hannah C., Lei, U. Wang, Sundarrajan, Ashmitha, Junday, Keerat, Pewarchuk, Michelle, Yeo, Abrey J., Kijas, Amanda W., Lavin, Martin F. and Wolvetang, Ernst J. (2020). Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses. Human Molecular Genetics, 29 (6), 990-1001. doi: 10.1093/hmg/ddaa023 |
2020 Journal Article Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid developmentGlass, Nick R., Takasako, Minoru, Er, Pei Xuan, Titmarsh, Drew M., Hidalgo, Alejandro, Wolvetang, Ernst J., Little, Melissa H. and Cooper-White, Justin J. (2020). Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development. Science Advances, 6 (2) eaaw2746, 1-13. doi: 10.1126/sciadv.aaw2746 |
2020 Journal Article Induced pluripotent stem cell-derived mesenchymal stem cells from the Tasmanian devil (Sarcophilus harrisii) express immunomodulatory factors and a tropism toward devil facial tumor cellsWeeratunga, Prasanna, Shahsavari, Arash, Fennis, Evelien, Wolvetang, Ernst J., Ovchinnikov, Dmitry A. and Whitworth, Deanne J. (2020). Induced pluripotent stem cell-derived mesenchymal stem cells from the Tasmanian devil (Sarcophilus harrisii) express immunomodulatory factors and a tropism toward devil facial tumor cells. Stem Cells and Development, 29 (1), 25-37. doi: 10.1089/scd.2019.0203 |
2019 Journal Article Inflammatory responses to a pathogenic West Nile virus strainHuang, Bixing, West, Nic, Vider, Jelena, Zhang, Ping, Griffiths, Rebecca E., Wolvetang, Ernst, Burtonclay, Peter and Warrilow, David (2019). Inflammatory responses to a pathogenic West Nile virus strain. BMC Infectious Diseases, 19 (1) 912, 912. doi: 10.1186/s12879-019-4471-8 |
2019 Journal Article Determinants of Zika virus host tropism uncovered by deep mutational scanningSetoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4 |
2019 Other Outputs Use of human iPSCs and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy to treat cystinosisHollywood, Jennifer A., Przepiorski, Aneta, Harrison, Patrick T., Wolvetang, Ernst J., Davidson, Alan J. and Holm, Teresa M. (2019). Use of human iPSCs and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy to treat cystinosis. doi: 10.1101/595264 |
2019 Journal Article Dynamic methylation of an L1 transduction family during reprogramming and neurodifferentiationSalvador-Palomeque, Carmen, Sanchez-Luque, Francisco J., Fortuna, Patrick R. J., Ewing, Adam D., Wolvetang, Ernst J., Richardson, Sandra R. and Faulkner, Geoffrey J. (2019). Dynamic methylation of an L1 transduction family during reprogramming and neurodifferentiation. Molecular and Cellular Biology, 39 (7) e00499-18, 1-19. doi: 10.1128/mcb.00499-18 |
2019 Journal Article GRGD-decorated three-dimensional nanoworm hydrogels for culturing human embryonic stem cellsKessel, Stefanie, Thakar, Nilay, Jia, Zhongfan, Wolvetang, Ernst J. and Monteiro, Michael J. (2019). GRGD-decorated three-dimensional nanoworm hydrogels for culturing human embryonic stem cells. Journal of Polymer Science Part A: Polymer Chemistry, 57 (18), 1956-1963. doi: 10.1002/pola.29342 |
2019 Journal Article Platypus induced pluripotent stem cells: the unique pluripotency signature of a monotremeWhitworth, Deanne J., Limnios, Ioannis J., Gauthier, Marie-Emilie, Weeratunga, Prasanna, Ovchinnikov, Dmitry A., Baillie, Gregory, Grimmond, Sean M., Graves, Jennifer A. Marshall and Wolvetang, Ernst J. (2019). Platypus induced pluripotent stem cells: the unique pluripotency signature of a monotreme. Stem Cells and Development, 28 (3), 151-164. doi: 10.1089/scd.2018.0179 |
2019 Journal Article Global proteomic and methylome analysis in human induced pluripotent stem cells reveals overexpression of a human TLR3 affecting proper innate immune response signalingRequena, J., Alvarez-Palomo, A. B., Codina-Pascual, M., Delgado-Morales, R., Moran, S., Esteller, M., Sal, M., Juan, M., Boronat Barado, A., Consiglio, A., Bogle, O. A., Wolvetang, E., Ovchinnikov, D., Alvarez, I., Jaraquemada, D., Mezquita-Pla, J., Oliva, R. and Edel, M. J. (2019). Global proteomic and methylome analysis in human induced pluripotent stem cells reveals overexpression of a human TLR3 affecting proper innate immune response signaling. Stem Cells, 37 (4), 476-488. doi: 10.1002/stem.2966 |
2018 Journal Article Evaluation of variability in human kidney organoidsPhipson, Belinda, Er, Pei X., Combes, Alexander N., Forbes, Thomas A., Howden, Sara E., Zappia, Luke, Yen, Hsan-Jan, Lawlor, Kynan T., Hale, Lorna J., Sun, Jane, Wolvetang, Ernst, Takasato, Minoru, Oshlack, Alicia and Little, Melissa H. (2018). Evaluation of variability in human kidney organoids. Nature Methods, 16 (1), 79-87. doi: 10.1038/s41592-018-0253-2 |
2018 Journal Article Identification of on-target mutagenesis during correction of a beta-thalassemia splice mutation in iPS cells with optimised CRISPR/Cas9-double nickase reveals potential safety concernsAlateeq, Suad, Ovchinnikov, Dmitry, Tracey, Timothy, Whitworth, Deanne, Al-Rubaish, Abdullah, Al-Ali, Amein and Wolvetang, Ernst (2018). Identification of on-target mutagenesis during correction of a beta-thalassemia splice mutation in iPS cells with optimised CRISPR/Cas9-double nickase reveals potential safety concerns. APL Bioengineering, 2 (4) 046103, 046103. doi: 10.1063/1.5048625 |
2018 Journal Article Erratum to: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells (Nature Communications, (2016), 7, 1, (10286), 10.1038/ncomms10286)Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Muñoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Cañadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Merkert, Sylvia, Gerdes, Patricia, Pulgarin, J. Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Sarkadi, Balázs, Löwer, Johannes, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltán, Izsvák, Zsuzsanna, Garcia-Perez, Jose L., Faulkner, Geoffrey J. and Schumann, Gerald G. (2018). Erratum to: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells (Nature Communications, (2016), 7, 1, (10286), 10.1038/ncomms10286). Nature Communications, 9 (1) 5398, 5398. doi: 10.1038/s41467-018-07917-0 |