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2021 Journal Article Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoidsAguado, Julio, Chaggar, Harman K., Gómez‐Inclán, Cecilia, Shaker, Mohammed R., Leeson, Hannah C., Mackay‐Sim, Alan and Wolvetang, Ernst J. (2021). Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids. Aging Cell, 20 (9) e13468, 1-16. doi: 10.1111/acel.13468 |
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2021 Journal Article Klotho inhibits neuronal senescence in human brain organoidsShaker, Mohammed R., Aguado, Julio, Chaggar, Harman Kaur and Wolvetang, Ernst J. (2021). Klotho inhibits neuronal senescence in human brain organoids. npj Aging and Mechanisms of Disease, 7 (1) 18, 1-12. doi: 10.1038/s41514-021-00070-x |
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2021 Conference Publication Direct comparison of improved method for human induced pluripotent stem cell (IPSC) haematopoietic differentiation shows enhanced efficiency and sensitivity at reduced costTursky, Melinda, Alateeq, Suad, Artuz, Crisbel, Loi, To Ha, Ma, David, Molloy, Tim, Tao, Helen and Wolvetang, Ernst (2021). Direct comparison of improved method for human induced pluripotent stem cell (IPSC) haematopoietic differentiation shows enhanced efficiency and sensitivity at reduced cost. ISEH 50th Annual Scientific Meeting, Online, 26 August - 30 November 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2021.12.350 |
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2021 Journal Article TDP-43 mutation affects stress granule dynamics in differentiated NSC-34 motoneuron-like cellsDing, Qiao, Chaplin, Justin, Morris, Matthew J., Hilliard, Massimo A., Wolvetang, Ernst, Ng, Dominic C. H. and Noakes, Peter G. (2021). TDP-43 mutation affects stress granule dynamics in differentiated NSC-34 motoneuron-like cells. Frontiers in Cell and Developmental Biology, 9 611601, 611601. doi: 10.3389/fcell.2021.611601 |
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2021 Journal Article Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer linesAlharbi, Samah Abdulaali, Ovchinnikov, Dmitry A. and Wolvetang, Ernst (2021). Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines. World Journal of Gastroenterology, 27 (15), 1578-1594. doi: 10.3748/WJG.V27.I15.1578 |
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2021 Journal Article Rapid and efficient generation of myelinating human oligodendrocytes in organoidsShaker, Mohammed R., Pietrogrande, Giovanni, Martin, Sally, Lee, Ju-Hyun, Woong, Sun and Wolvetang, Ernst J. (2021). Rapid and efficient generation of myelinating human oligodendrocytes in organoids. Frontiers in Cellular Neuroscience, 15 631548, 1-11. doi: 10.3389/fncel.2021.631548 |
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2021 Journal Article Antiplasmodial and antileishmanial flavonoids from Mundulea sericeaChepkirui, Carolyne, Ochieng, Purity J., Sarkar, Biswajyoti, Hussain, Aabid, Pal, Chiranjib, Yang, Li Jun, Coghi, Paolo, Akala, Hoseah M., Derese, Solomon, Ndakala, Albert, Heydenreich, Matthias, Wong, Vincent K. W., Erdelyi, Mate and Yenesew, Abiy (2021). Antiplasmodial and antileishmanial flavonoids from Mundulea sericea. Fitoterapia, 149 104796, 1-6. doi: 10.1016/j.fitote.2020.104796 |
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2021 Journal Article Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasiaYeo, Abrey J., Kok, Chong L., Gatei, Magtouf, Zou, Dongxiu, Stewart, Romal, Withey, Sarah, Wolvetang, Ernst, Parton, Robert G., Brown, Adam D., Kastan, Michael B., Coman, David and Lavin, Martin F. (2021). Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia. iScience, 24 (1) 101972, 101972. doi: 10.1016/j.isci.2020.101972 |
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2021 Journal Article Testing the correlates of consciousness in brain organoids: how do we know and what do we do?Ankeny, Rachel A. and Wolvetang, Ernst (2021). Testing the correlates of consciousness in brain organoids: how do we know and what do we do?. The American Journal of Bioethics, 21 (1), 51-53. doi: 10.1080/15265161.2020.1845869 |
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2020 Journal Article Self-organizing 3D human choroid plexus-ventricle-cortical organoidsShaker, Mohammed R. , Cooper-White, Justin and Wolvetang, Ernst J. (2020). Self-organizing 3D human choroid plexus-ventricle-cortical organoids. |
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2020 Journal Article Direct comparison of four hematopoietic differentiation methods from human induced pluripotent stem cellsTursky, Melinda L., Loi, To Ha, Artuz, Crisbel M., Alateeq, Suad, Wolvetang, Ernst J., Tao, Helen, Ma, David D. and Molloy, Timothy J. (2020). Direct comparison of four hematopoietic differentiation methods from human induced pluripotent stem cells. Stem Cell Reports, 15 (3), 735-748. doi: 10.1016/j.stemcr.2020.07.009 |
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2020 Journal Article Telomere transcription in AgeingAguado, Julio, d’Adda di Fagagna, Fabrizio and Wolvetang, Ernst (2020). Telomere transcription in Ageing. Ageing Research Reviews, 62 101115, 101115. doi: 10.1016/j.arr.2020.101115 |
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2020 Conference Publication Thyroid hormone and TGF-? inhibition drive functional maturation of human pluripotent stem cell-derived hepatocytesWithey, Sarah, Gerrard, Dave, Leeson, Hannah, Atkinson-Dell, Rebecca, Harrison, Sean, Baxter, Melissa, Al-Anbaki, Ali, Hanley, Karen Piper, Wolvetang, Ernst and Hanley., Neil (2020). Thyroid hormone and TGF-? inhibition drive functional maturation of human pluripotent stem cell-derived hepatocytes. EASL: The Digital International Liver Congress, Online, 27-29 August 2020. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s0168-8278(20)31000-x |
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2020 Conference Publication Zika Virus sfRNA plays an essential role in the infection of insects and mammalsSlonchak, Andrii, Hugo, Leon E., Freney, Morgan, Amarilla, Alberto A., Hall-Mendelin, Sonja, Yan, Kexin, Torres, Francisco, Setoh, Yin Xiang, Peng, Nias, Chaggar, Harman K., Hurk, Andrew Van Den, Wolvetang, Ernst, Suhrbier, Andreas, Devine, Gregor J. and Khromykh, Alexander A. (2020). Zika Virus sfRNA plays an essential role in the infection of insects and mammals. Viruses 2020—Novel Concepts in Virology, Barcelona, Spain, 5–7 February 2020. Basel, Switzerland: MDPI. doi: 10.3390/proceedings2020050112 |
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2020 Journal Article Use of human induced pluripotent stem cells and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy for cystinosisHollywood, Jennifer A., Przepiorski, Aneta, D'Souza, Randall F., Sreebhavan, Sreevalsan, Wolvetang, Ernst J., Harrison, Patrick T., Davidson, Alan J. and Holm, Teresa M. (2020). Use of human induced pluripotent stem cells and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy for cystinosis. Journal of the American Society of Nephrology , 31 (5), 962-982. doi: 10.1681/ASN.2019070712 |
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2020 Journal Article Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responsesOvchinnikov, Dmitry A., Withey, Sarah L., Leeson, Hannah C., Lei, U. Wang, Sundarrajan, Ashmitha, Junday, Keerat, Pewarchuk, Michelle, Yeo, Abrey J., Kijas, Amanda W., Lavin, Martin F. and Wolvetang, Ernst J. (2020). Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses. Human Molecular Genetics, 29 (6), 990-1001. doi: 10.1093/hmg/ddaa023 |
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2020 Journal Article Induced pluripotent stem cell-derived mesenchymal stem cells from the Tasmanian devil (Sarcophilus harrisii) express immunomodulatory factors and a tropism toward devil facial tumor cellsWeeratunga, Prasanna, Shahsavari, Arash, Fennis, Evelien, Wolvetang, Ernst J., Ovchinnikov, Dmitry A. and Whitworth, Deanne J. (2020). Induced pluripotent stem cell-derived mesenchymal stem cells from the Tasmanian devil (Sarcophilus harrisii) express immunomodulatory factors and a tropism toward devil facial tumor cells. Stem Cells and Development, 29 (1), 25-37. doi: 10.1089/scd.2019.0203 |
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2020 Journal Article Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid developmentGlass, Nick R., Takasako, Minoru, Er, Pei Xuan, Titmarsh, Drew M., Hidalgo, Alejandro, Wolvetang, Ernst J., Little, Melissa H. and Cooper-White, Justin J. (2020). Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development. Science Advances, 6 (2) eaaw2746, 1-13. doi: 10.1126/sciadv.aaw2746 |
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2019 Journal Article Inflammatory responses to a pathogenic West Nile virus strainHuang, Bixing, West, Nic, Vider, Jelena, Zhang, Ping, Griffiths, Rebecca E., Wolvetang, Ernst, Burtonclay, Peter and Warrilow, David (2019). Inflammatory responses to a pathogenic West Nile virus strain. BMC Infectious Diseases, 19 (1) 912, 912. doi: 10.1186/s12879-019-4471-8 |
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2019 Journal Article Determinants of Zika virus host tropism uncovered by deep mutational scanningSetoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4 |
