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2016 Journal Article Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cellsKlawitter, Sabine, Fuchs,Nina V., Upton, Kyle R., Munoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Canadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Merkert, Sylvia, Gerdes, Patricia, Pulgarin, J. Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Sarkadi, Balazs, Lower, Johannes, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltan, Izsvak, Zsuzsanna, Garcia-Perez, Jose L., Faulkner, Geoffrey J. and Schumann, Gerald G. (2016). Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. Nature Communications, 7 (1) 10286, 1-14. doi: 10.1038/ncomms10286 |
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2016 Conference Publication Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasiaQuek, H., Luff, J., Cheung, K., Kozlov, S., Gatei, M., Lee, C. S., Bellingham, M., Noakes, P., Lim, Y. C., Barnett, N., Dingwall, S., Wolvetang, E., Mashimo, T., Roberts, T. and Lavin, M. (2016). Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia. International Congress of Immunology (ICI), Melbourne, VIC Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Chondro-inductive injectable hydrogels for stem cell-based intervertebral disc tissue engineeringNaidoo, Taryn, Frith, Jessica, Menzies, Donna, Pradal, Clementine, Cameron, Andrew, Wolvetang, Ernst, Grondahl, Lisbeth, Whitehead, Darryl, Gronthos, Stan, Zannettino, Andrew, Ghosh, Peter and Cooper-White, Justin (2016). Chondro-inductive injectable hydrogels for stem cell-based intervertebral disc tissue engineering. 10th World Biomaterials Congress, Montreal, Canada, 17-22 May 2016. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.fbioe.2016.01.02659 |
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2016 Journal Article Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd edition) (vol 12, pg 1, 2015)Kliosnky, D., Ernst Wolvetang and Mark J. Walker (2016). Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd edition) (vol 12, pg 1, 2015). Autophagy, 12 (2), 443-443. doi: 10.1080/15548627.2016.1147886 |
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2016 Conference Publication Reprogramming initiates mobilization of endogenous mutagenic LINE-1, Alu and SVA retrotransposons in human induced pluripotent stem cells with consequences for host gene expressionSchumann, Gerald, Jung-Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Munoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Canadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Gerdes, Patricia, Merkert, Sylvia, Pulgarin, Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltan, Izsvak, Zsuzsanna, Garcia-Perez, J. and Faulkner, Geoffrey J. (2016). Reprogramming initiates mobilization of endogenous mutagenic LINE-1, Alu and SVA retrotransposons in human induced pluripotent stem cells with consequences for host gene expression. Frontiers of Retrovirology Conference 2016, Erlangen, Germany, 12 - 14 September 2016. London, United Kingdom: BioMed Central. doi: 10.1186/s12977-016-0294-5 |
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2015 Journal Article The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosomeHurst, Laurence D., Ghanbarian, Avazeh T., Forrest, Alistair R. R., Huminiecki, Lukasz, Rehli, Michael, Baillie, J. Kenneth, de Hoon, Michiel J. L., Haberle, Vanja, Lassmann, Timo, Kulakovskiy, Ivan V., Lizio, Marina, Itoh, Masayoshi, Andersson, Robin, Mungall, Christopher J., Meehan, Terrence F., Schmeier, Sebastian, Bertin, Nicolas, Jorgensen, Mette, Dimont, Emmanuel, Arner, Erik, Schmidl, Christian, Schaefer, Ulf, Medvedeva, Yulia A., Plessy, Charles, Vitezic, Morana, Severin, Jessica, Semple, Colin A., Ishizu, Yuri, Young, Robert S. ... Hayashizaki, Yoshihide (2015). The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome. PLoS Biology, 13 (12) e1002315, e1002315. doi: 10.1371/journal.pbio.1002315 |
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2015 Journal Article Generation of footprint-free induced pluripotent stem cells from human fibroblasts using episomal plasmid vectorsOvchinnikov, Dmitry A., Sun, Jane and Wolvetang, Ernst J. (2015). Generation of footprint-free induced pluripotent stem cells from human fibroblasts using episomal plasmid vectors. Methods in Molecular Biology, 1330, 37-45. doi: 10.1007/978-1-4939-2848-4_4 |
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2015 Journal Article Mechanisms of long non-coding RNAs in mammalian nervous system development, plasticity, disease, and evolutionBriggs, James A., Wolvetang, Ernst J., Mattick, John S., Rinn, John L. and Barry, Guy (2015). Mechanisms of long non-coding RNAs in mammalian nervous system development, plasticity, disease, and evolution. Neuron, 88 (5), 861-877. doi: 10.1016/j.neuron.2015.09.045 |
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2015 Journal Article Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesisTakasato, Minoru, Er, Pei X., Chiu, Han S., Maier, Barbara, Baillie, Gregory J., Ferguson, Charles, Parton, Robert G., Wolvetang, Ernst J., Roost, Matthias S., de Sousa Lopes, Susana M. Chuva and Little, Melissa H. (2015). Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 526 (7574), 564-568. doi: 10.1038/nature15695 |
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2015 Journal Article A protocol for the identification and validation of novel genetic causes of kidney diseaseMallett, Andrew, Patel, Chirag, Maier, Barbara, McGaughran, Julie, Gabbett, Michael, Takasato, Minoru, Cameron, Anne, Trnka, Peter, Alexander, Stephen I., Rangan, Gopala, Tchan, Michel C., Caruana, Georgina, John, George, Quinlan, Cathy, McCarthy, Hugh J., Hyland, Valentine, Hoy, Wedy E., Wolvetang, Ernst, Taft, Ryan, Simons, Cas, Healy H. and Little, Melissa (2015). A protocol for the identification and validation of novel genetic causes of kidney disease. BMC Nephrology, 16 (152) 148, 152. doi: 10.1186/s12882-015-0148-8 |
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2015 Conference Publication Multiplexed Microbioreactor Arrays for Rapid Optimisation of Pluripotent Stem Cell Maintenance and DifferentiationTitmarsh, D., Glass, N., Hudson, J., Hidalgo, A., Porrello, E., Little, M., Wolvetang, E. and Cooper-White, J. (2015). Multiplexed Microbioreactor Arrays for Rapid Optimisation of Pluripotent Stem Cell Maintenance and Differentiation. 4th TERMIS World Congress, Boston Ma, Sep 08-11, 2015. NEW ROCHELLE: MARY ANN LIEBERT, INC. |
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2015 Journal Article Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic DevelopmentHasegawa, Yu., Taylor, Deanne., Ovchinnikov, Dmitry A., Wolvetang, Ernst J., de Torrente, Laurence. and Mar, Jessica C. (2015). Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development. PLoS Genetics, 11 (8) e1005428, e1005428. doi: 10.1371/journal.pgen.1005428 |
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2015 Journal Article A new model to study neurodegeneration in ataxia oculomotor apraxia type 2Becherel, Olivier J., Sun, Jane, Yeo, Abrey J., Nayler, Sam, Fogel, Brent L., Gao, Fuying, Coppola, Giovanni, Criscuolo, Chiara, De Michele, Giuseppe, Wolvetang, Ernst and Lavin, Martin F. (2015). A new model to study neurodegeneration in ataxia oculomotor apraxia type 2. Human Molecular Genetics, 24 (20), 5759-5774. doi: 10.1093/hmg/ddv296 |
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2015 Journal Article Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cellsArner, Erik, Daub, Carsten O., Vitting-Seerup, Kristoffer, Andersson, Robin, Lilje, Berit, Drabløs, Finn, Lennartsson, Andreas, Rönnerblad, Michelle, Hrydziuszko, Olga, Vitezic, Morana, Freeman, Tom C., Alhendi, Ahmad M. N., Arner, Peter, Axton, Richard, Baillie, J. Kenneth, Beckhouse, Anthony, Bodega, Beatrice, Briggs, James, Brombacher, Frank, Davis, Margaret, Detmar, Michael, Ehrlund, Anna, Endoh, Mitsuhiro, Eslami, Afsaneh, Fagiolini, Michela, Fairbairn, Lynsey, Faulkner, Geoffrey J., Ferrai, Carmelo, Fisher, Malcolm E. ... Hayashizaki, Yoshihide (2015). Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science, 347 (6225), 1010-1014. doi: 10.1126/science.1259418 |
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2015 Journal Article High-throughput, deterministic single cell trapping and long-term clonal cell culture in microfluidic devicesChen, Huaying, Sun, Jane, Wolvetang, Ernst and Cooper-White, Justin (2015). High-throughput, deterministic single cell trapping and long-term clonal cell culture in microfluidic devices. Lab on a Chip, 15 (4), 1072-1083. doi: 10.1039/C4LC01176G |
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2015 Journal Article TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation.Thakar, Nilay Y., Ovchinnikov, Dmitry A., Hastie, Marcus L., Kobe, Bostjan, Gorman, Jeffrey J. and Wolvetang, Ernst J. (2015). TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation.. Molecular Biology of the Cell, 26 (5), 993-1006. doi: 10.1091/mbc.E14-08-1290 |
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2015 Book Chapter Ascorbate as a modulator of the epigenomeThakar, Nilay Y. and Wolvetang, Ernst J. (2015). Ascorbate as a modulator of the epigenome. Nutrition and epigenetics. (pp. 199-218) edited by Emily Ho and Frederick Domann. Boca Raton, FL, United States: CRC Press. doi: 10.1201/b17530-11 |
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2015 Journal Article Advances in reprogramming to pluripotencyAlateeq, Suad, Fortuna, Patrick R. J. and Wolvetang, Ernst (2015). Advances in reprogramming to pluripotency. Current Stem Cell Research and Therapy, 10 (3), 193-207. doi: 10.2174/1574888X10666150220154820 |
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2015 Conference Publication Platypus Induced Pluripotent Stem Cells Reveal that Acquisition of SOX2 Responsiveness Facilitated Expansion of the Pluripotency Network During Mammalian EvolutionWhitworth, D. J., Gauthier, M.-E., Ovchinnikov, D. A., Grimmond, S. M., Marshall Graves, J. A. and Wolvetang, E. J. (2015). Platypus Induced Pluripotent Stem Cells Reveal that Acquisition of SOX2 Responsiveness Facilitated Expansion of the Pluripotency Network During Mammalian Evolution. Annual Meeting of the International Society for Stem Cell Research, Stockholm , Sweden, 24-27 June 2015. |
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2015 Journal Article ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1Kijas, Amanda W., Lim, Yi Chieh, Bolderson, Emma, Cerosaletti, Karen, Gatei, Magtouf, Jakob, Burkhard, Tobias, Frank, Taucher-Scholz, Gisela, Gueven, Nuri, Oakley, Greg, Concannon, Patrick, Wolvetang, Ernst, Khanna, Kum Kum, Wiesmuller, Lisa and Lavin, Martin F. (2015). ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. Nucleic Acids Research, 43 (17), 8352-8367. doi: 10.1093/nar/gkv754 |
