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2017

Journal Article

Mitochondrial dysfunction and mitophagy in neurodegenerative diseases

Kao, L. P. and Wolvetang, E. J. (2017). Mitochondrial dysfunction and mitophagy in neurodegenerative diseases. Cell and Developmental Biology, 6 doi: 10.4172/2168-9296.1000184

Mitochondrial dysfunction and mitophagy in neurodegenerative diseases

2017

Journal Article

DNA methylation in schizophrenia in different patient-derived cell types

Vitale, Alejandra M., Matigian, Nicholas A., Cristino, Alexandre S., Nones, Katia, Ravishankar, Sugandha, Bellette, Bernadette, Fan, Yongjun, Wood, Stephen A., Wolvetang, Ernst and Mackay-Sim, Alan (2017). DNA methylation in schizophrenia in different patient-derived cell types. Schizophrenia, 3 (1) 6, 1-11. doi: 10.1038/s41537-016-0006-0

DNA methylation in schizophrenia in different patient-derived cell types

2017

Journal Article

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states

Barry, Guy, Briggs, James A., Hwang, Do Won, Nayler, Sam P., Fortuna, Patrick R. J., Jonkhout, Nicky, Dachet, Fabien, Maag, Jesper L. V., Mestdagh, Pieter, Singh, Erin M., Avesson, Lotta, Kaczorowski, Dominik C., Ozturk, Ezgi, Jones, Nigel C., Vetter, Irina, Arriola-Martinez, Luis, Hu, Jianfei, Franco, Gloria R., Warn, Victoria M., Gong, Andrew, Dinger, Marcel E., Rigo, Frank, Lipovich, Leonard, Morris, Margaret J., O'Brien, Terence J., Lee, Dong Soo, Loeb, Jeffrey A., Blackshaw, Seth, Mattick, John S. and Wolvetang, Ernst J. (2017). The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states. Scientific Reports, 7 (1) 40127, 40127. doi: 10.1038/srep40127

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states

2017

Conference Publication

Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain

Woodruff, Trent M., Hawksworth, Owen A., Li, Rui, Balachandran, Anushree, Leel, John D., Sepehrband', Farshid, Kurniawan, Nyoman, Jeanes, Angela, Simmons, David G., Wolvetang, Ernst and Coulthard, Liam G. (2017). Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain. 16th European Meeting on Complement in Human Disease (EMCHD), Copenhagen Denmark, 8-12 September 2017. Kidlington, Oxford United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2017.06.178

Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain

2017

Book Chapter

Lentiviral reprogramming of A-T patient fibroblasts to induced pluripotent stem cells

Nayler, Sam, Kozlov, Sergei V., Lavin, Martin F. and Wolvetang, Ernst (2017). Lentiviral reprogramming of A-T patient fibroblasts to induced pluripotent stem cells. In Sergei V. Kozlov (Ed.), ATM kinase: methods and protocols (pp. 401-418) New York, NY, United States: Humana Press; Springer Science+Business Media. doi:10.1007/978-1-4939-6955-5_29

Lentiviral reprogramming of A-T patient fibroblasts to induced pluripotent stem cells

2016

Journal Article

Therapeutic targets and investigated treatments for Ataxia-Telangiectasia

Lavin, Martin F., Yeo, Abrey J., Kijas, Amanda W., Wolvetang, Ernst, Sly, Peter D., Wainwright, Claire and Sinclair, Kate (2016). Therapeutic targets and investigated treatments for Ataxia-Telangiectasia. Expert Opinion on Orphan Drugs, 4 (12), 1263-1276. doi: 10.1080/21678707.2016.1254618

Therapeutic targets and investigated treatments for Ataxia-Telangiectasia

2016

Journal Article

Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage

Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C. Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. Journal of Leukocyte Biology, 101 (4), 927-947. doi: 10.1189/jlb.4VMA0716-316R

Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage

2016

Journal Article

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype

Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype. Human Molecular Genetics, 26 (1), 109-123. doi: 10.1093/hmg/ddw371

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype

2016

Journal Article

Antagonizing STAT5B dimerization with an osmium complex

Liu, Li-Juan, Wang, Wanhe, Kang, Tian-Shu, Liang, Jia-Xin, Liu, Chenfu, Kwong, Daniel W. J., Wong, Vincent Kam Wai, Ma, Dik-Lung and Leung, Chung-Hang (2016). Antagonizing STAT5B dimerization with an osmium complex. Scientific Reports, 6 36044. doi: 10.1038/srep36044

Antagonizing STAT5B dimerization with an osmium complex

2016

Journal Article

Profiling ribonucleotide and deoxyribonucleotide pools perturbed by gemcitabine in human non-small cell lung cancer cells

Guo, Jian-Ru, Chen, Qian-Qian, Lam, Christopher Wai Kei, Wang, Cai-Yun, Wong, Vincent Kam Wai, Chang, Zee-Fen and Zhang, Wei (2016). Profiling ribonucleotide and deoxyribonucleotide pools perturbed by gemcitabine in human non-small cell lung cancer cells. Scientific Reports, 6 (1) 37250. doi: 10.1038/srep37250

Profiling ribonucleotide and deoxyribonucleotide pools perturbed by gemcitabine in human non-small cell lung cancer cells

2016

Journal Article

Corrigendum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

Takasato, Minoru, Er, Pei X., Chiu, Han S., Maier, Barbara, Baillie, Gregory J., Ferguson, Charles, Parton, Robert G., Wolvetang, Ernst J., Roost, Matthias S., Lopes, Susana M. Chuva de Sousa and Little, Melissa H. (2016). Corrigendum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 536 (7615), 238-238. doi: 10.1038/nature17982

Corrigendum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

2016

Journal Article

AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation

Cullen, Jason K., Murad, Norazian Abdul, Yeo, Abrey, McKenzie, Matthew, Ward, Micheal, Chong, Kok Leong, Schieber, Nicole L., Parton, Robert G., Lim, Yi Chieh, Wolvetang, Ernst, Maghzal, Ghassan J., Stocker, Roland and Lavin, Martin F. (2016). AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation. Plos One, 11 (7) e0160162, e0160162. doi: 10.1371/journal.pone.0160162

AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation

2016

Journal Article

Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays

Titmarsh, Drew M., Glass, Nick R., Mills, Richard J., Hidalgo, Alejandro, Wolvetang, Ernst J., Porrello, Enzo R., Hudson, James E. and Cooper-White, Justin J. (2016). Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays. Scientific Reports, 6 (1) 24637, 24637. doi: 10.1038/srep24637

Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays

2016

Journal Article

AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation

Cullen, Jason K., Murad, Norazian Abdul, Yeo, Abrey, McKenzie, Matthew, Ward, Micheal, Chong, Kok Leong, Schieber, Nicole L., Parton, Robert G., Lim, Yi Chieh, Wolvetang, Ernst, Maghzal, Ghassan J., Stocker, Roland and Lavin, Martin F. (2016). AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation. PLoS One, 11 (2) e0148213, e0148213. doi: 10.1371/journal.pone.0148213

AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation

2016

Other Outputs

Brain cells transformed from blood: a cell model for investigating autism

Dawson, Paul A., Heussler, Helen, Wolvetang, Ernst, Lee, Soohyun and Thakar, Nilay (2016). Brain cells transformed from blood: a cell model for investigating autism. Brisbane, QLD, Australia: Autism CRC.

Brain cells transformed from blood: a cell model for investigating autism

2016

Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, Daniel J., et al., Wolvetang, Ernst and Walker, Mark J. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12 (1), 1-222. doi: 10.1080/15548627.2015.1100356

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

2016

Journal Article

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

Klawitter, Sabine, Fuchs,Nina V., Upton, Kyle R., Munoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Canadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Merkert, Sylvia, Gerdes, Patricia, Pulgarin, J. Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Sarkadi, Balazs, Lower, Johannes, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltan, Izsvak, Zsuzsanna, Garcia-Perez, Jose L., Faulkner, Geoffrey J. and Schumann, Gerald G. (2016). Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. Nature Communications, 7 (1) 10286, 1-14. doi: 10.1038/ncomms10286

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

2016

Conference Publication

Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia

Quek, H., Luff, J., Cheung, K., Kozlov, S., Gatei, M., Lee, C. S., Bellingham, M., Noakes, P., Lim, Y. C., Barnett, N., Dingwall, S., Wolvetang, E., Mashimo, T., Roberts, T. and Lavin, M. (2016). Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia. International Congress of Immunology (ICI), Melbourne, VIC Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Neuroinflammation drives the neuronal degenerative phenotype in a rat model of Ataxia-telangiectasia

2016

Conference Publication

Chondro-inductive injectable hydrogels for stem cell-based intervertebral disc tissue engineering

Naidoo, Taryn, Frith, Jessica, Menzies, Donna, Pradal, Clementine, Cameron, Andrew, Wolvetang, Ernst, Grondahl, Lisbeth, Whitehead, Darryl, Gronthos, Stan, Zannettino, Andrew, Ghosh, Peter and Cooper-White, Justin (2016). Chondro-inductive injectable hydrogels for stem cell-based intervertebral disc tissue engineering. 10th World Biomaterials Congress, Montreal, Canada, 17-22 May 2016. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.fbioe.2016.01.02659

Chondro-inductive injectable hydrogels for stem cell-based intervertebral disc tissue engineering

2016

Journal Article

Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd edition) (vol 12, pg 1, 2015)

Kliosnky, D., Ernst Wolvetang and Mark J. Walker (2016). Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd edition) (vol 12, pg 1, 2015). Autophagy, 12 (2), 443-443. doi: 10.1080/15548627.2016.1147886

Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd edition) (vol 12, pg 1, 2015)