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2022 Journal Article Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutationsLeeson, Hannah C., Goh, Denise, Coman, David and Wolvetang, Ernst J. (2022). Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutations. Stem Cell Research, 64 102917, 1-5. doi: 10.1016/j.scr.2022.102917 |
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2022 Journal Article Generation of human induced pluripotential stem cells from individuals with complex heterozygous, isogenic corrected, and homozygous Bloc1s1 mutationsWu, Kaiyuan, Takanohashi, Asako, Woidill, Sarah, Seylani, Allen, Helman, Guy, Dias, Patricia, Beers, Jeanette, Lin, Yongshun, Simons, Cas, Wolvetang, Ernst, Zou, Jizhong, Vanderver, Adeline and Sack, Michael N. (2022). Generation of human induced pluripotential stem cells from individuals with complex heterozygous, isogenic corrected, and homozygous Bloc1s1 mutations. Stem Cell Research, 64 102905, 1-6. doi: 10.1016/j.scr.2022.102905 |
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2022 Conference Publication A human iPSC-based cardiac tissue model to understand age-related heart failureGopalakrishnan, Aswathi, Wolvetang, Ernst, Li, Joan and Cooper-White, Justin (2022). A human iPSC-based cardiac tissue model to understand age-related heart failure. Tissue Engineering and Regenerative Medicine International Society Asia Pacific Chapter Conference (TERMIS-AP), Jeju, South Korea, 5-8 October 2022. New Rochelle, NY United States: Mary Ann Liebert. |
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2022 Journal Article Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η proteinGao, Zhenxiong, Fan, Tingting, Chen, Linbo, Yang, Mengchu, Wong, Vincent Kam Wai, Chen, Dawei, Liu, Zijian, Zhou, Yaoyao, Wu, Weibin, Qiu, Zixuan, Zhang, Cunlong, Li, Yuan and Jiang, Yuyang (2022). Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein. European Journal of Medicinal Chemistry, 238 114402, 1-15. doi: 10.1016/j.ejmech.2022.114402 |
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2022 Journal Article The hallmarks of aging in ataxia-telangiectasiaAguado, Julio, Gómez-Inclán, Cecilia, Leeson, Hannah C., Lavin, Martin F., Shiloh, Yosef and Wolvetang, Ernst J. (2022). The hallmarks of aging in ataxia-telangiectasia. Ageing Research Reviews, 79 101653, 1-15. doi: 10.1016/j.arr.2022.101653 |
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2022 Journal Article Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variantsIsaacs, Ariel, Amarilla, Alberto A., Aguado, Julio, Modhiran, Naphak, Albornoz, Eduardo A., Baradar, Alireza A., McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, McMillan, Nigel A. J., Muller, David A., Young, Paul R., Woodruff, Trent M., Wolvetang, Ernst J., Chappell, Keith J. and Watterson, Daniel (2022). Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants. Frontiers in Immunology, 13 926262, 926262. doi: 10.3389/fimmu.2022.926262 |
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2022 Journal Article Robust and highly reproducible generation of cortical brain organoids for modelling brain neuronal senescence in vitroShaker, Mohammed R., Hunter, Zoe L. and Wolvetang, Ernst J. (2022). Robust and highly reproducible generation of cortical brain organoids for modelling brain neuronal senescence in vitro. Journal of Visualized Experiments, 2022 (183) e63714. doi: 10.3791/63714 |
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2022 Journal Article Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron DiseaseDing, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5 |
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2022 Conference Publication Age-dependent changes in perivascular stem cells and the impacts of altered sensing on vascular ageingCooper-White, Justin, Chowdhury, Mahfuz, Wolvetang, Ernst and Veleva, Desi (2022). Age-dependent changes in perivascular stem cells and the impacts of altered sensing on vascular ageing. TERMIS 6th World Congress, Maastricht, Netherlands, 15-19 November 2021. New Rochelle, NY United States: Mary Ann Liebert. |
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2022 Journal Article Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screeningHunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2022). Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening. Stem Cell Research, 60 102673, 102673. doi: 10.1016/j.scr.2022.102673 |
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2022 Conference Publication Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomesCooper-White, Justin, Chowdhury, Mahfuz, Wolvetang, Ernst, Zimmerman, Samuel, Mar, Jessica, Polo, Jose, Laslett, Andrew and Nefzger, Christian (2022). Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomes. TERMIS 6th World Congress, Maastricht, Netherlands, 15-19 November 2021. New Rochelle, NY United States: Mary Ann Liebert. |
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2022 Journal Article Inhibition of the CDK9-cyclin T1 protein-protein interaction as a new approach against triple-negative breast cancerCheng, Sha-Sha, Qu, Yuan-Qing, Wu, Jia, Yang, Guan-Jun, Liu, Hao, Wang, Wanhe, Huang, Qi, Chen, Feng, Li, Guodong, Wong, Chun-Yuen, Wong, Vincent Kam Wai, Ma, Dik-Lung and Leung, Chung-Hang (2022). Inhibition of the CDK9-cyclin T1 protein-protein interaction as a new approach against triple-negative breast cancer. Acta Pharmaceutica Sinica B, 12 (3), 1390-1405. doi: 10.1016/j.apsb.2021.10.024 |
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2022 Journal Article 2-Bromo-3-((1-(7-chloroquinolin-4-yl)-1H-1,2,3-triazol-4-yl)-methoxy)-benzaldehydeYun, Xiaoyun, Xie, Yuhan, Ng, Jerome P. L., Law, Betty Yuen Kwan, Wong, Vincent Kam Wai and Coghi, Paolo (2022). 2-Bromo-3-((1-(7-chloroquinolin-4-yl)-1H-1,2,3-triazol-4-yl)-methoxy)-benzaldehyde. Molbank, 2022 (1) M1351, 1-7. doi: 10.3390/M1351 |
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2022 Journal Article Exploring aging interventions in human brain organoidsAguado, Julio and Wolvetang, Ernst J (2022). Exploring aging interventions in human brain organoids. Aging, 14 (4), 1592-1593. doi: 10.18632/aging.203925 |
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2022 Journal Article Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell typesShaker, Mohammed R., Kahtan, Amna, Prasad, Renuka, Lee, Ju-Hyun, Pietrogrande, Giovanni, Leeson, Hannah C., Sun, Woong, Wolvetang, Ernst J. and Slonchak, Andrii (2022). Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types. Frontiers in Cell and Developmental Biology, 10 803061, 803061. doi: 10.3389/fcell.2022.803061 |
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2022 Journal Article Nimbolide inhibits 2D and 3D prostate cancer cells migration, affects microtubules and angiogenesis and suppresses B-RAF/p.ERK-mediated in vivo tumor growthMahmoud, Nuha, Dawood, Mona, Huang, Qi, Ng, Jerome P. L., Ren, Fang, Wong, Vincent K. W. and Efferth, Thomas (2022). Nimbolide inhibits 2D and 3D prostate cancer cells migration, affects microtubules and angiogenesis and suppresses B-RAF/p.ERK-mediated in vivo tumor growth. Phytomedicine, 94 153826, 1-13. doi: 10.1016/j.phymed.2021.153826 |
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2021 Journal Article Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural networkGrapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2021). Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. Nature Communications, 12 (1) 3297. doi: 10.1038/s41467-021-23143-7 |
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2021 Journal Article Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patientsHunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2021). Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients. Stem Cell Research, 56 102564, 102564. doi: 10.1016/j.scr.2021.102564 |
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2021 Journal Article Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohortLeeson, Hannah C., Hunter, Zoe, Chaggar, Harman Kaur, Mackay-Sim, Alan and Wolvetang, Ernst J. (2021). Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohort. Stem Cell Research, 56 102527, 102527. doi: 10.1016/j.scr.2021.102527 |
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2021 Journal Article Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutationsLeeson, Hannah C., Hunter, Zoe, Chaggar, Harman Kaur, Lavin, Martin F., Mackay-Sim, Alan and Wolvetang, Ernst J. (2021). Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutations. Stem Cell Research, 56 102528, 102528. doi: 10.1016/j.scr.2021.102528 |
