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2022 Journal Article Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron DiseaseDing, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5 |
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2022 Journal Article Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screeningHunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2022). Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening. Stem Cell Research, 60 102673, 102673. doi: 10.1016/j.scr.2022.102673 |
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2022 Conference Publication Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomesCooper-White, Justin, Chowdhury, Mahfuz, Wolvetang, Ernst, Zimmerman, Samuel, Mar, Jessica, Polo, Jose, Laslett, Andrew and Nefzger, Christian (2022). Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomes. TERMIS 6th World Congress, Maastricht, Netherlands, 15-19 November 2021. New Rochelle, NY United States: Mary Ann Liebert. |
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2022 Conference Publication Age-dependent changes in perivascular stem cells and the impacts of altered sensing on vascular ageingCooper-White, Justin, Chowdhury, Mahfuz, Wolvetang, Ernst and Veleva, Desi (2022). Age-dependent changes in perivascular stem cells and the impacts of altered sensing on vascular ageing. TERMIS 6th World Congress, Maastricht, Netherlands, 15-19 November 2021. New Rochelle, NY United States: Mary Ann Liebert. |
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2022 Journal Article Inhibition of the CDK9-cyclin T1 protein-protein interaction as a new approach against triple-negative breast cancerCheng, Sha-Sha, Qu, Yuan-Qing, Wu, Jia, Yang, Guan-Jun, Liu, Hao, Wang, Wanhe, Huang, Qi, Chen, Feng, Li, Guodong, Wong, Chun-Yuen, Wong, Vincent Kam Wai, Ma, Dik-Lung and Leung, Chung-Hang (2022). Inhibition of the CDK9-cyclin T1 protein-protein interaction as a new approach against triple-negative breast cancer. Acta Pharmaceutica Sinica B, 12 (3), 1390-1405. doi: 10.1016/j.apsb.2021.10.024 |
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2022 Journal Article 2-Bromo-3-((1-(7-chloroquinolin-4-yl)-1H-1,2,3-triazol-4-yl)-methoxy)-benzaldehydeYun, Xiaoyun, Xie, Yuhan, Ng, Jerome P. L., Law, Betty Yuen Kwan, Wong, Vincent Kam Wai and Coghi, Paolo (2022). 2-Bromo-3-((1-(7-chloroquinolin-4-yl)-1H-1,2,3-triazol-4-yl)-methoxy)-benzaldehyde. Molbank, 2022 (1) M1351, 1-7. doi: 10.3390/M1351 |
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2022 Journal Article Exploring aging interventions in human brain organoidsAguado, Julio and Wolvetang, Ernst J (2022). Exploring aging interventions in human brain organoids. Aging, 14 (4), 1592-1593. doi: 10.18632/aging.203925 |
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2022 Journal Article Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell typesShaker, Mohammed R., Kahtan, Amna, Prasad, Renuka, Lee, Ju-Hyun, Pietrogrande, Giovanni, Leeson, Hannah C., Sun, Woong, Wolvetang, Ernst J. and Slonchak, Andrii (2022). Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types. Frontiers in Cell and Developmental Biology, 10 803061, 803061. doi: 10.3389/fcell.2022.803061 |
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2022 Journal Article Nimbolide inhibits 2D and 3D prostate cancer cells migration, affects microtubules and angiogenesis and suppresses B-RAF/p.ERK-mediated in vivo tumor growthMahmoud, Nuha, Dawood, Mona, Huang, Qi, Ng, Jerome P. L., Ren, Fang, Wong, Vincent K. W. and Efferth, Thomas (2022). Nimbolide inhibits 2D and 3D prostate cancer cells migration, affects microtubules and angiogenesis and suppresses B-RAF/p.ERK-mediated in vivo tumor growth. Phytomedicine, 94 153826, 1-13. doi: 10.1016/j.phymed.2021.153826 |
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2021 Journal Article Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural networkGrapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2021). Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. Nature Communications, 12 (1) 3297. doi: 10.1038/s41467-021-23143-7 |
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2021 Journal Article Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohortLeeson, Hannah C., Hunter, Zoe, Chaggar, Harman Kaur, Mackay-Sim, Alan and Wolvetang, Ernst J. (2021). Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohort. Stem Cell Research, 56 102527, 102527. doi: 10.1016/j.scr.2021.102527 |
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2021 Journal Article Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutationsLeeson, Hannah C., Hunter, Zoe, Chaggar, Harman Kaur, Lavin, Martin F., Mackay-Sim, Alan and Wolvetang, Ernst J. (2021). Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutations. Stem Cell Research, 56 102528, 102528. doi: 10.1016/j.scr.2021.102528 |
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2021 Journal Article Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patientsHunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2021). Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients. Stem Cell Research, 56 102564, 102564. doi: 10.1016/j.scr.2021.102564 |
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2021 Journal Article Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoidsAguado, Julio, Chaggar, Harman K., Gómez‐Inclán, Cecilia, Shaker, Mohammed R., Leeson, Hannah C., Mackay‐Sim, Alan and Wolvetang, Ernst J. (2021). Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids. Aging Cell, 20 (9) e13468, 1-16. doi: 10.1111/acel.13468 |
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2021 Journal Article Klotho inhibits neuronal senescence in human brain organoidsShaker, Mohammed R., Aguado, Julio, Chaggar, Harman Kaur and Wolvetang, Ernst J. (2021). Klotho inhibits neuronal senescence in human brain organoids. npj Aging and Mechanisms of Disease, 7 (1) 18, 1-12. doi: 10.1038/s41514-021-00070-x |
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2021 Conference Publication Direct comparison of improved method for human induced pluripotent stem cell (IPSC) haematopoietic differentiation shows enhanced efficiency and sensitivity at reduced costTursky, Melinda, Alateeq, Suad, Artuz, Crisbel, Loi, To Ha, Ma, David, Molloy, Tim, Tao, Helen and Wolvetang, Ernst (2021). Direct comparison of improved method for human induced pluripotent stem cell (IPSC) haematopoietic differentiation shows enhanced efficiency and sensitivity at reduced cost. ISEH 50th Annual Scientific Meeting, Online, 26 August - 30 November 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.exphem.2021.12.350 |
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2021 Journal Article TDP-43 mutation affects stress granule dynamics in differentiated NSC-34 motoneuron-like cellsDing, Qiao, Chaplin, Justin, Morris, Matthew J., Hilliard, Massimo A., Wolvetang, Ernst, Ng, Dominic C. H. and Noakes, Peter G. (2021). TDP-43 mutation affects stress granule dynamics in differentiated NSC-34 motoneuron-like cells. Frontiers in Cell and Developmental Biology, 9 611601, 611601. doi: 10.3389/fcell.2021.611601 |
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2021 Journal Article Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer linesAlharbi, Samah Abdulaali, Ovchinnikov, Dmitry A. and Wolvetang, Ernst (2021). Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines. World Journal of Gastroenterology, 27 (15), 1578-1594. doi: 10.3748/WJG.V27.I15.1578 |
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2021 Journal Article Antiplasmodial and antileishmanial flavonoids from Mundulea sericeaChepkirui, Carolyne, Ochieng, Purity J., Sarkar, Biswajyoti, Hussain, Aabid, Pal, Chiranjib, Yang, Li Jun, Coghi, Paolo, Akala, Hoseah M., Derese, Solomon, Ndakala, Albert, Heydenreich, Matthias, Wong, Vincent K. W., Erdelyi, Mate and Yenesew, Abiy (2021). Antiplasmodial and antileishmanial flavonoids from Mundulea sericea. Fitoterapia, 149 104796, 1-6. doi: 10.1016/j.fitote.2020.104796 |
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2021 Journal Article Rapid and efficient generation of myelinating human oligodendrocytes in organoidsShaker, Mohammed R., Pietrogrande, Giovanni, Martin, Sally, Lee, Ju-Hyun, Woong, Sun and Wolvetang, Ernst J. (2021). Rapid and efficient generation of myelinating human oligodendrocytes in organoids. Frontiers in Cellular Neuroscience, 15 631548, 1-11. doi: 10.3389/fncel.2021.631548 |
