|
2014 Journal Article The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmiasChen, Wenqian, Wang, Ruiwu, Chen, Biyi, Zhong, Xiaowei, Kong, Huihui, Bai, Yunlong, Zhou, Qiang, Xie, Cuihong, Zhang, Jingqun, Guo, Ang, Tian, Xixi, Jones, Peter P., O'Mara, Megan L., Liu, Yingjie, Mi, Tao, Zhang, Lin, Bolstad, Jeff, Semeniuk, Lisa, Cheng, Hongqiang, Zhang, Jianlin, Chen, Ju, Tieleman, D. Peter, Gillis, Anne M., Duff, Henry J., Fill, Michael, Song, Long-Sheng and Chen, S. R. Wayne (2014). The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias. Nature Medicine, 20 (2), 184-192. doi: 10.1038/nm.3440 |
|
2014 Journal Article Imperfect coordination chemistry facilitates metal ion release in the Psa permeaseCouñago, Rafael M., Ween, Miranda P., Begg, Stephanie L., Bajaj, Megha, Zuegg, Johannes, O'Mara, Megan L., Cooper, Matthew A., McEwan, Alastair G., Paton, James C., Kobe, Bostjan and McDevitt, Christopher A. (2014). Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology, 10 (1), 35-41. doi: 10.1038/nCHeMBIO.1382 |
|
2012 Journal Article The effect of environment on the structure of a membrane protein: P-glycoprotein under physiological conditionsO’Mara, Megan L. and Mark, Alan E. (2012). The effect of environment on the structure of a membrane protein: P-glycoprotein under physiological conditions. Journal of Chemical Theory and Computation, 8 (10), 3964-3976. doi: 10.1021/ct300254y |
|
2024 Journal Article Amphetamine-like Deferiprone and Clioquinol Derivatives as Iron Chelating AgentsEl Safadi, Mahmoud, Wilson, Katie A., Strudwicke, Indigo J., O’Mara, Megan L., Bhadbhade, Mohan, Rawling, Tristan and McDonagh, Andrew M. (2024). Amphetamine-like Deferiprone and Clioquinol Derivatives as Iron Chelating Agents. Molecules, 29 (17) 4213, 4213. doi: 10.3390/molecules29174213 |
|
2024 Journal Article How molecular architecture defines quantum yieldsPashley-Johnson, Fred, Munaweera, Rangika, Hossain, Sheikh I., Gauci, Steven C., Delafresnaye, Laura, Frisch, Hendrik, O’Mara, Megan L., Du Prez, Filip E. and Barner-Kowollik, Christopher (2024). How molecular architecture defines quantum yields. Nature Communications, 15 (1) 6033, 1-9. doi: 10.1038/s41467-024-50366-1 |
|
2024 Journal Article Lipidome modifications in A. baumannii alter membrane properties and antimicrobial peptide interactionsO'Mara, Megan L., MacDermott-Opeskin, Hugo and Wilson, Katie A. (2024). Lipidome modifications in A. baumannii alter membrane properties and antimicrobial peptide interactions. Biophysical Journal, 123 (3), 455a. doi: 10.1016/j.bpj.2023.11.2771 |
|
2024 Journal Article Main-chain macromolecular hydrazone photoswitchesThai, Linh Duy, Fanelli, Julian, Munaweera, Rangika, O'Mara, Megan L., Barner-Kowollik, Christopher and Mutlu, Hatice (2024). Main-chain macromolecular hydrazone photoswitches. Angewandte Chemie - International Edition, 63 (4) e202315887, 1-12. doi: 10.1002/anie.202315887 |
|
2024 Journal Article Introduction to the <i>RSC Advances</i> themed collection on <i>New insights into biomolecular systems from large-scale simulations</i>O’Mara, Megan L., Rauscher, Sarah and Wetmore, Stacey D. (2024). Introduction to the RSC Advances themed collection on New insights into biomolecular systems from large-scale simulations. RSC Advances, 14 (10), 6985-6986. doi: 10.1039/d4ra90012j |
|
2023 Journal Article The efficacy of the analgesic GlyT2 inhibitor, ORG25543, is determined by two connected allosteric sitesChater, Ryan Cantwell, Quinn, Ada S., Wilson, Katie, Frangos, Zachary J., Sutton, Patrick, Jayakumar, Srinivasan, Cioffi, Christopher L., O'Mara, Megan L. and Vandenberg, Robert J. (2023). The efficacy of the analgesic GlyT2 inhibitor, ORG25543, is determined by two connected allosteric sites. Journal of Neurochemistry. doi: 10.1111/jnc.16028 |
|
2023 Journal Article The net electrostatic potential and hydration of ABCG2 affect substrate transportGose, Tomoka, Aitken, Heather M., Wang, Yao, Lynch, John, Rampersaud, Evadnie, Fukuda, Yu, Wills, Medb, Baril, Stefanie A., Ford, Robert C., Shelat, Anang, O'Mara, Megan L. and Schuetz, John D. (2023). The net electrostatic potential and hydration of ABCG2 affect substrate transport. Nature Communications, 14 (1) 5035, 5035. doi: 10.1038/s41467-023-40610-5 |
|
2023 Journal Article Structural basis of promiscuous substrate transport by Organic Cation Transporter 1Zeng, Yi C., Sobti, Meghna, Quinn, Ada, Smith, Nicola J., Brown, Simon H.J., Vandenberg, Jamie I., Ryan, Renae M., O'Mara, Megan L. and Stewart, Alastair G. (2023). Structural basis of promiscuous substrate transport by Organic Cation Transporter 1. Nature Communications, 14 (1) 6374, 1-14. doi: 10.1038/s41467-023-42086-9 |
|
2023 Journal Article Extracellular vesicle lipids in cancer immunoevasionChen, Siyu, Iannotta, Dalila, O'Mara, Megan L., Goncalves, Jenifer Pendiuk and Wolfram, Joy (2023). Extracellular vesicle lipids in cancer immunoevasion. Trends in Cancer, 9 (11), 883-886. doi: 10.1016/j.trecan.2023.08.006 |
|
2023 Journal Article Visible light reactive single‐chain nanoparticlesMundsinger, Kai, Tuten, Bryan T., Wang, Lily, Neubauer, Kira, Kropf, Christian, O'Mara, Megan L. and Barner-Kowollik, Christopher (2023). Visible light reactive single‐chain nanoparticles. Angewandte Chemie, 135 (23) e202302995. doi: 10.1002/ange.202302995 |
|
2023 Journal Article Visible-Light-Reactive Single-Chain NanoparticlesMundsinger, Kai, Tuten, Bryan T., Wang, Lily, Neubauer, Kira, Kropf, Christian, O'Mara, Megan L. and Barner-Kowollik, Christopher (2023). Visible-Light-Reactive Single-Chain Nanoparticles. Angewandte Chemie - International Edition, 62 (23) e202302995, e202302995. doi: 10.1002/anie.202302995 |
|
2023 Journal Article The impact of antimicrobial peptides on the Acinetobacter baumannii inner membrane is modulated by lipid polyunsaturationMacDermott-Opeskin, Hugo I., Wilson, Katie A. and O’Mara, Megan L. (2023). The impact of antimicrobial peptides on the Acinetobacter baumannii inner membrane is modulated by lipid polyunsaturation. ACS Infectious Diseases, 9 (4), 815-826. doi: 10.1021/acsinfecdis.2c00530 |
|
2023 Conference Publication Identification and characterisation of lipids that are positive allosteric modulators of glycine receptorsGallagher, Casey I., Lin, Yie Chang, Kumar, Arvind, Ha, Damian, Cioffi, Christopher L., Chakrapani, Sudha, O'Mara, Megan L. and Vandenberg, Robert J. (2023). Identification and characterisation of lipids that are positive allosteric modulators of glycine receptors. 66th Annual Meeting of the Biophysical-Society, San Francisco Ca, Feb 19-23, 2022. CAMBRIDGE: CELL PRESS. |
|
2023 Conference Publication Identification and characterisation of lipids that are positive allosteric modulators of glycine receptorsGallagher, Casey I., Chang Lin, Yie, Kumar, Arvind, Ha, Damian, Cioffi, Christopher L., Chakrapani, Sudha, O'Mara, Megan L. and Vandenberg, Robert J. (2023). Identification and characterisation of lipids that are positive allosteric modulators of glycine receptors. 67th Biophysical Society Annual Meeting 2023, San Diego, CA United States, 18-22 February 2023. St Louis, MO United States: Cell Press. doi: 10.1016/j.bpj.2022.11.2138 |
|
2023 Conference Publication Polyunsaturated lipids promote membrane phase separation and antimicrobial sensitivityMacDermott-Opeskin, Hugo, Wilson, Katie A., Eijkelkamp, Bart and O'Mara, Megan L. (2023). Polyunsaturated lipids promote membrane phase separation and antimicrobial sensitivity. Biophysical Society 67th Annual Meeting, San Diego, CA United States, 18-22 February 2023. St. Louis, MO United States: Cell Press. doi: 10.1016/j.bpj.2022.11.1805 |
|
2023 Journal Article Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2Frangos, Zachary J., Wilson, Katie A., Aitken, Heather M., Cantwell Chater, Ryan, Vandenberg, Robert J. and O’Mara, Megan L. (2023). Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2. Life Science Alliance, 6 (4) e202201708, 1-17. doi: 10.26508/lsa.202201708 |
|
2022 Journal Article Protonophoric and mitochondrial uncoupling activity of aryl-carbamate substituted fatty acidsMacDermott-Opeskin, Hugo, Clarke, Callum, Wu, Xin, Roseblade, Ariane, York, Edward, Pacchini, Ethan, Roy, Ritik, Cranfield, Charles, Gale, Philip A., O'Mara, Megan L., Murray, Michael and Rawling, Tristan (2022). Protonophoric and mitochondrial uncoupling activity of aryl-carbamate substituted fatty acids. Organic and Biomolecular Chemistry, 21 (1), 132-139. doi: 10.1039/d2ob02049a |
