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2018 Journal Article The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environmentCondic-Jurkic, Karmen, Subramanian, Nandhitha, Mark, Alan E. and O'Mara, Megan L. (2018). The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment. PloS One, 13 (1) e0191882, 1-24. doi: 10.1371/journal.pone.0191882 |
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2017 Journal Article Capturing the dynamics of a spring-loaded proteinMitchell, Joshua A. and O'Mara, Megan L. (2017). Capturing the dynamics of a spring-loaded protein. Structure, 25 (7), 963-964. doi: 10.1016/j.str.2017.06.008 |
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2017 Journal Article A potential new, stable state of the E-cadherin strand-swapped dimer in solutionSchumann-Gillett, Alexandra, Mark, Alan E., Deplazes, Evelyne and O'Mara, Megan L. (2017). A potential new, stable state of the E-cadherin strand-swapped dimer in solution. European Biophysics Journal, 47 (1), 59-67. doi: 10.1007/s00249-017-1229-3 |
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2017 Journal Article Hydrogen bond-driven self–assembly between amidinium cations and carboxylate anions: a combined molecular dynamics, NMR spectroscopy, and single crystal X-ray diffraction studyThomas, Michael, Anglim Lagones, Thomas, Judd, Martyna, Morshedi, Mahbod, O'Mara, Megan L. and White, Nicholas G. (2017). Hydrogen bond-driven self–assembly between amidinium cations and carboxylate anions: a combined molecular dynamics, NMR spectroscopy, and single crystal X-ray diffraction study. Chemistry - An Asian Journal, 12 (13), 1587-1597. doi: 10.1002/asia.201700406 |
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2017 Book Chapter Method for developing optical sensors using a synthetic dye-fluorescent protein FRET pair and computational modeling and assessmentMitchell, Joshua A., Zhang, William H., Herde, Michel K., Henneberger, Christian, Janovjak, Harald, O’Mara, Megan L. and Jackson, Colin J. (2017). Method for developing optical sensors using a synthetic dye-fluorescent protein FRET pair and computational modeling and assessment. Synthetic Protein Switches: Methods and Protocols. (pp. 89-99) New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-6940-1_6 |
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2017 Journal Article Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate bindingAnandan, Anandhi, Evans, Genevieve L., Condic-Jurkic, Karmen, O'Mara, Megan L., John, Constance M., Phillips, Nancy J., Jarvis, Gary A., Wills, Siobhan S., Stubbs, Keith A., Moraes, Isabel, Kahler, Charlene M. and Vrielink, Alice (2017). Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding. Proceedings of the National Academy of Sciences of the United States of America, 114 (9), 2218-2223. doi: 10.1073/pnas.1612927114 |
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2017 Book Chapter Thylakoid ultrastructure: visualizing the photosynthetic machinerySteinbeck, Janina, O’Mara, Megan L., Ross, Ian L., Stahlberg, Henning and Hankamer, Ben (2017). Thylakoid ultrastructure: visualizing the photosynthetic machinery. Chlamydomonas: Biotechnology and Biomedicine. (pp. 149-191) edited by Michael Hippler. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-66360-9_7 |
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2017 Journal Article Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNAKretzmann, Jessica A., Ho, Diwei, Evans, Cameron W., Plani-Lam, Janice H. C., Garcia-Bloj, Benjamin, Mohamed, A. Elaaf, O'Mara, Megan L., Ford, Ethan, Tan, Dennis E. K., Lister, Ryan, Blancafort, Pilar, Norret, Marck and Iyer, K. Swaminathan (2017). Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA. Chemical Science, 8 (4), 2923-2930. doi: 10.1039/c7sc00097a |
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2017 Journal Article Simple design of an enzyme-inspired supported catalyst based on a catalytic triadNothling, Mitchell D., Ganesan, Aravindhan, Condic-Jurkic, Karmen, Pressly, Eric, Davalos, Ashley, Gotrik, Michael R., Xiao, Zeyun, Khoshdel, Ezat, Hawker, Craig J., O'Mara, Megan L., Coote, Michelle L. and Connal, Luke A. (2017). Simple design of an enzyme-inspired supported catalyst based on a catalytic triad. Chem, 2 (5), 732-745. doi: 10.1016/j.chempr.2017.04.004 |
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2017 Journal Article Erratum: Simple Design of an Enzyme-Inspired Supported Catalyst Based on a Catalytic Triad (Chem (2017) 2(5) (732–745) (S2451929417301705) (10.1016/j.chempr.2017.04.004))Nothling, Mitchell D., Ganesan, Aravindhan, Condic-Jurkic, Karmen, Pressly, Eric, Davalos, Ashley, Gotrik, Michael R., Xiao, Zeyun, Khoshdel, Ezat, Hawker, Craig J., O'Mara, Megan L., Coote, Michelle L. and Connal, Luke A. (2017). Erratum: Simple Design of an Enzyme-Inspired Supported Catalyst Based on a Catalytic Triad (Chem (2017) 2(5) (732–745) (S2451929417301705) (10.1016/j.chempr.2017.04.004)). Chem, 2 (6), 893-894. doi: 10.1016/j.chempr.2017.05.015 |
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2017 Journal Article Location of contact residues in pharmacologically distinct drug binding sites on P-glycoproteinMittra, Rituparna, Pavy, Megan, Subramanian, Nanditha, George, Anthony M., O'Mara, Megan L., Kerr, Ian D. and Callaghan, Richard (2017). Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein. Biochemical Pharmacology, 123, 19-28. doi: 10.1016/j.bcp.2016.10.002 |
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2016 Journal Article Rangefinder: a semisynthetic FRET sensor design algorithmMitchell, Joshua A., Whitfield, Jason H., Zhang, William H., Henneberger, Christian, Janovjak, Harald, O'Mara, Megan L. and Jackson, Colin J. (2016). Rangefinder: a semisynthetic FRET sensor design algorithm. ACS Sensors, 1 (11), 1286-1290. doi: 10.1021/acssensors.6b00576 |
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2016 Journal Article Hydrophobic shielding drives catalysis of hydride transfer in a family of F420H2-dependent enzymesMohamed, A. Elaaf, Condic-Jurkic, Karmen, Ahmed, F. Hafna, Yuan, Peng, O'Mara, Megan L., Jackson, Colin J. and Coote, Michelle L. (2016). Hydrophobic shielding drives catalysis of hydride transfer in a family of F420H2-dependent enzymes. Biochemistry, 55 (49), 6908-6918. doi: 10.1021/acs.biochem.6b00683 |
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2016 Journal Article Rv2074 is a novel F420H2-dependent biliverdin reductase in Mycobacterium tuberculosisAhmed, F. Hafna, Mohamed, A. Elaaf, Carr, Paul D., Lee, Brendon M., Condic-Jurkic, Karmen, O'Mara, Megan L. and Jackson, Colin J. (2016). Rv2074 is a novel F420H2-dependent biliverdin reductase in Mycobacterium tuberculosis. Protein Science, 25 (9), 1692-1709. doi: 10.1002/pro.2975 |
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2016 Journal Article Correction: Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2Subramanian, Nandhitha, Scopelliti, Amanda J., Carland, Jane E., Ryan, Renae M., O'Mara, Megan L. and Vandenberg, Robert J. (2016). Correction: Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2. PLoS One, 11 (7) e0159896, e0159896. doi: 10.1371/journal.pone.0159896 |
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2016 Journal Article Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2Subramanian, Nandhitha, Scopelitti, Amanda J., Carland, Jane E., Ryan, Renae M., O'Mara, Megan L. and Vandenberg, Robert J. (2016). Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2. PLoS ONE, 11 (6) e0157583, e0157583. doi: 10.1371/journal.pone.0157583 |
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2016 Journal Article Structural and dynamic perspectives on the promiscuous transport activity of P-glycoproteinSubramanian, Nandhitha, Condic-Jurkic, Karmen and O'Mara, Megan L. (2016). Structural and dynamic perspectives on the promiscuous transport activity of P-glycoprotein. Neurochemistry International, 98, 146-152. doi: 10.1016/j.neuint.2016.05.005 |
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2016 Journal Article Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioningSubramanian, Nandhitha, Schumann-Gillett, Alexandra, Mark, Alan E. and O'Mara, Megan L. (2016). Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioning. Biochimica et Biophysica Acta: Biomembranes, 1858 (4), 776-782. doi: 10.1016/j.bbamem.2015.12.025 |
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2016 Conference Publication Going downstream - how does GH binding activate JAK2Brooks, Andrew, Dai, W., O'Mara, M. L., Abankwa, D., Chhabra, Y., Pelekanos, R. A., Gardon, O., Tunny, K. A., Blucher, K. M., Morton, C. J., Parker, M. W., Sierecki, E., Gambin, Y., Gomez, G. A., Alexandrov, K., Wilson, I. A., Doxastakis, M., Mark, A. E. and Waters, M. J. (2016). Going downstream - how does GH binding activate JAK2. Annual Scientific Meeting of the Endocrine Society of Australia, Adelaide, Australia, 23-26 August, 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/cen.13010 |
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2016 Conference Publication Mechanism of JAK2 Activation by the Archetype Class I Cytokine Receptor, the Growth Hormone ReceptorBrooks, Andrew J., O’Mara, Megan L., Dai, Wei, Abankwa, Daniel, Chhabra, Yash, Tunny, Kathryn A., Parker, Michael W., Sierecki, Emma, Gambin, Yann, Gomez, Guillermo A., Haxholm, Gitte W., Nikolajsen, Louise F., Doxastakis, Manolis, Mark, Alan E. and Waters, Michael J. (2016). Mechanism of JAK2 Activation by the Archetype Class I Cytokine Receptor, the Growth Hormone Receptor. Biophysical Meeting, Los Angeles, CA, United States, 27 February - 2 March 2016. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2015.11.233 |
