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2024 Journal Article Metabolic aspects of genetic ion channel epilepsiesNeal, Elliott S., Xu, Weizhi and Borges, Karin (2024). Metabolic aspects of genetic ion channel epilepsies. Journal of Neurochemistry, 168 (12), 3911-3935. doi: 10.1111/jnc.15938 |
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2024 Journal Article “Brain propane’’: Propionate Fuels the Brain in Mice With Brain Energy DeficitsNeal, Elliott S. and Borges, Karin (2024). “Brain propane’’: Propionate Fuels the Brain in Mice With Brain Energy Deficits. Epilepsy Currents, 15357597241293843. doi: 10.1177/15357597241293843 |
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2024 Journal Article DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long TermBodea, Liviu-Gabriel and Borges, Karin (2024). DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long Term. Epilepsy Currents, 24 (6), 420-422. doi: 10.1177/15357597241279761 |
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2024 Journal Article Case for supporting astrocyte energetics in glucose transporter 1 deficiency syndromeXu, Weizhi and Borges, Karin (2024). Case for supporting astrocyte energetics in glucose transporter 1 deficiency syndrome. Epilepsia, 65 (8), 2213-2226. doi: 10.1111/epi.18013 |
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2024 Journal Article The benefits of “spoilt milk”: lactic acid can limit excitability via HCAR1Borges, Karin (2024). The benefits of “spoilt milk”: lactic acid can limit excitability via HCAR1. Epilepsy Currents, 24 (3), 206-208. doi: 10.1177/15357597241249037 |
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2024 Journal Article Transient anticonvulsant effects of time-restricted feeding in the 6-Hz mouse modelArmstrong, Oliver J., Neal, Elliott S., Vidovic, Diana, Xu, Weizhi and Borges, Karin (2024). Transient anticonvulsant effects of time-restricted feeding in the 6-Hz mouse model. Epilepsy and Behavior, 151 109618. doi: 10.1016/j.yebeh.2023.109618 |
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2024 Journal Article Brain energy metabolism: A roadmap for future researchRae, Caroline D., Baur, Joseph A., Borges, Karin, Dienel, Gerald, Díaz‐García, Carlos Manlio, Douglass, Starlette R., Drew, Kelly, Duarte, João M. N., Duran, Jordi, Kann, Oliver, Kristian, Tibor, Lee‐Liu, Dasfne, Lindquist, Britta E., McNay, Ewan C., Robinson, Michael B., Rothman, Douglas L., Rowlands, Benjamin D., Ryan, Timothy A., Scafidi, Joseph, Scafidi, Susanna, Shuttleworth, C. William, Swanson, Raymond A., Uruk, Gökhan, Vardjan, Nina, Zorec, Robert and McKenna, Mary C. (2024). Brain energy metabolism: A roadmap for future research. Journal of Neurochemistry, 168 (5), 910-954. doi: 10.1111/jnc.16032 |
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2023 Journal Article Vitamin B12 deficiency induces glucose intolerance, delays peak insulin levels and promotes ketogenesis in female ratsNeal, Elliott, Kumar, Vinod, Borges, Karin and Cuffe, James S.M. (2023). Vitamin B12 deficiency induces glucose intolerance, delays peak insulin levels and promotes ketogenesis in female rats. The Journal of Endocrinology, 256 (2) e220158, 1-16. doi: 10.1530/joe-22-0158 |
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2022 Journal Article Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure modelsXu, Weizhi, Neal, Elliott S., Plan, Manuel and Borges, Karin (2022). Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models. Epilepsy and Behavior, 137 (Part A) 108964, 108964. doi: 10.1016/j.yebeh.2022.108964 |
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2022 Journal Article Potential new roles for glycogen in epilepsyDienel, Gerald A., Gillinder, Lisa, McGonigal, Aileen and Borges, Karin (2022). Potential new roles for glycogen in epilepsy. Epilepsia, 64 (1), 29-53. doi: 10.1111/epi.17412 |
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2022 Journal Article β-hydroxybutyrate and medium-chain fatty acids are metabolized by different cell types in mouse cerebral cortex slicesAndersen, Jens V., Westi, Emil W., Neal, Elliott S., Aldana, Blanca I. and Borges, Karin (2022). β-hydroxybutyrate and medium-chain fatty acids are metabolized by different cell types in mouse cerebral cortex slices. Neurochemical Research, 48 (1), 1-8. doi: 10.1007/s11064-022-03726-6 |
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2022 Journal Article Brain glycogen content is increased in the acute and interictal chronic stages of the mouse pilocarpine model of epilepsyYoung Seo, Gi, Neal, Elliott S., Han, Felicity, Vidovic, Diana, Nooru‐Mohamed, Fathima, Dienel, Gerald A., Sullivan, Mitchell A. and Borges, Karin (2022). Brain glycogen content is increased in the acute and interictal chronic stages of the mouse pilocarpine model of epilepsy. Epilepsia Open, 7 (2), 361-367. doi: 10.1002/epi4.12599 |
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2021 Journal Article Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supplyAndersen, Jens V., Westi, Emil W., Jakobsen, Emil, Urruticoechea, Nerea, Borges, Karin and Aldana, Blanca I. (2021). Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply. Molecular Brain, 14 (1) 132, 1-13. doi: 10.1186/s13041-021-00842-2 |
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2021 Journal Article Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in miceXu, Weizhi, Maqbool, Faheem, Kumar, Vinod, Falconer, James R., Cui, Cedric S., Woodruff, Trent M., Borges, Karin, Whittaker, Andrew K., Smith, Maree T. and Han, Felicity Y. (2021). Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice. Drug Delivery and Translational Research, 12 (10), 2518-2526. doi: 10.1007/s13346-021-01093-3 |
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2021 Journal Article Fructose 1,6-bisphosphate is anticonvulsant and improves oxidative glucose metabolism within the hippocampus and liver in the chronic pilocarpine mouse epilepsy modelMcDonald, Tanya S., Neal, Elliott S. and Borges, Karin (2021). Fructose 1,6-bisphosphate is anticonvulsant and improves oxidative glucose metabolism within the hippocampus and liver in the chronic pilocarpine mouse epilepsy model. Epilepsy and Behavior, 122 108223, 1-9. doi: 10.1016/j.yebeh.2021.108223 |
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2021 Journal Article Dietary medium chain triglycerides for management of epilepsy: new data from human, dog, and rodent studiesHan, Felicity Y., Conboy‐Schmidt, Lisa, Rybachuk, Galena, Volk, Holger A., Zanghi, Brian, Pan, Yuanlong and Borges, Karin (2021). Dietary medium chain triglycerides for management of epilepsy: new data from human, dog, and rodent studies. Epilepsia, 62 (8) epi.16972, 1790-1806. doi: 10.1111/epi.16972 |
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2021 Journal Article CNS glucose metabolism in amyotrophic lateral sclerosis: a therapeutic target?Tefera, Tesfaye Wolde, Steyn, Frederik J., Ngo, Shyuan T. and Borges, Karin (2021). CNS glucose metabolism in amyotrophic lateral sclerosis: a therapeutic target?. Cell & Bioscience, 11 (1) 14, 14. doi: 10.1186/s13578-020-00511-2 |
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2020 Journal Article Open label long term treatment of add-on triheptanoin in adults with drug-resistant epilepsyBorges, Karin, Kaul, Neha, Germaine, Jack, Carrasco-Pozo, Catalina, Kwan, Patrick and O'Brien, Terence J. (2020). Open label long term treatment of add-on triheptanoin in adults with drug-resistant epilepsy. Epilepsia Open, 5 (2), 230-239. doi: 10.1002/epi4.12391 |
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2020 Journal Article Combined diffusion tensor imaging and quantitative susceptibility mapping discern discrete facets of white matter pathology post-injury in the rodent brainSoni, Neha, Vegh, Viktor, To, Xuan Vinh, Mohamed, Abdalla Z., Borges, Karin and Nasrallah, Fatima A. (2020). Combined diffusion tensor imaging and quantitative susceptibility mapping discern discrete facets of white matter pathology post-injury in the rodent brain. Frontiers in Neurology, 11 153, 1-16. doi: 10.3389/fneur.2020.00153 |
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2020 Journal Article Prenatal betamethasone exposure increases corticotropin-releasing hormone expression along with increased hippocampal slice excitability in the developing hippocampusBenson, Melissa J., Lauková, Marcela, Borges, Karin, Velíšková, Jana and Velíšek, Libor (2020). Prenatal betamethasone exposure increases corticotropin-releasing hormone expression along with increased hippocampal slice excitability in the developing hippocampus. Epilepsy Research, 160 106276, 106276. doi: 10.1016/j.eplepsyres.2020.106276 |
