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2016 Journal Article Triheptanoin protects motor neurons and delays the onset of motor symptoms in a mouse model of amyotrophic lateral sclerosisTefera, Tesfaye W., Wong, Yide, Barkl-Luke, Mallory E., Ngo, Shyuan T., Thomas, Nicola K., McDonald, Tanya S. and Borges, Karin (2016). Triheptanoin protects motor neurons and delays the onset of motor symptoms in a mouse model of amyotrophic lateral sclerosis. Plos One, 11 (8) e0161816, e0161816. doi: 10.1371/journal.pone.0161816 |
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2016 Journal Article Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial functionTan, Kah Ni, Carrasco-Pozo, Catalina, McDonald, Tanya S., Puchowicz, Michelle and Borges, Karin (2016). Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function. Journal Of Cerebral Blood Flow and Metabolism, 37 (6), 2035-2048. doi: 10.1177/0271678X16659498 |
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2015 Journal Article Sulforaphane is anticonvulsant and improves mitochondrial functionCarrasco-Pozo, Catalina, Tan, Kah Ni and Borges, Karin (2015). Sulforaphane is anticonvulsant and improves mitochondrial function. Journal of Neurochemistry, 135 (5), 932-942. doi: 10.1111/jnc.13361 |
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2015 Journal Article Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-l-CarnitineHadera, Mussie Ghezu, McDonald, Tanya, Smeland, Olav B., Meisingset, Tore W., Eloqayli, Haytham, Jaradat, Saied, Borges, Karin and Sonnewald, Ursula (2015). Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-l-Carnitine. Neurochemical Research, 41 (1-2), 86-95. doi: 10.1007/s11064-015-1728-5 |
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2015 Journal Article Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse modelsBenson, Melissa J., Manzanero, Silvia and Borges, Karin (2015). Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models. Epilepsia, 56 (6), 895-905. doi: 10.1111/epi.12960 |
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2015 Journal Article A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy modelsBenson, Melissa J, Thomas, Nicola K, Talwar, Sahil, Hodson, Mark P, Lynch, Joseph W, Woodruff, Trent M and Borges, Karin (2015). A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models. Neurobiology of Disease, 76, 87-97. doi: 10.1016/j.nbd.2015.02.004 |
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2014 Journal Article Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsHadera, Mussie G., Smeland, Olav B., McDonald, Tanya S., Tan, Kah Ni, Sonnewald, Ursula and Borges, Karin (2014). Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epileps. Journal of Neurochemistry, 129 (1), 107-119. doi: 10.1111/jnc.12610 |
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2014 Journal Article Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglyceridesMcDonald, Tanya S., Tan, Kah Ni, Hodson, Mark P. and Borges, Karin (2014). Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglycerides. Journal Of Cerebral Blood Flow and Metabolism, 34 (1), 153-160. doi: 10.1038/jcbfm.2013.184 |
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2013 Journal Article Slc10A4-what do we know about the function of this "secret ligand carrier" protein?Borges, Karin (2013). Slc10A4-what do we know about the function of this "secret ligand carrier" protein?. Experimental Neurology, 248, 258-261. doi: 10.1016/j.expneurol.2013.06.019 |
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2013 Journal Article Anticonvulsant screening of luteolin in four mouse seizure modelsShaikh, Mohd Farooq, Tan, Kah Ni and Borges, Karin (2013). Anticonvulsant screening of luteolin in four mouse seizure models. Neuroscience Letters, 550, 195-199. doi: 10.1016/j.neulet.2013.06.065 |
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2013 Journal Article Brain mitochondrial metabolic dysfunction and glutamate level reduction in the pilocarpine model of temporal lobe epilepsy in miceSmeland, Olav B., Hadera, Mussie G., McDonald, Tanya S., Sonnewald, Ursula and Borges, Karin (2013). Brain mitochondrial metabolic dysfunction and glutamate level reduction in the pilocarpine model of temporal lobe epilepsy in mice. Journal of Cerebral Blood Flow and Metabolism, 33 (7), 1090-1097. doi: 10.1038/jcbfm.2013.54 |
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2013 Journal Article Triheptanoin reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsyKim, Tae Hwan, Borges, Karin, Petrou, Steven and Reid, Christopher A. (2013). Triheptanoin reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsy. Epilepsy Research, 103 (1), 101-105. doi: 10.1016/j.eplepsyres.2012.09.016 |
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2012 Journal Article Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy miceSmeland, Olav B., Meisingset, Tore W., Borges, Karin and Sonnewald, Ursula (2012). Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice. Neurochemistry International, 61 (1), 100-107. doi: 10.1016/j.neuint.2012.04.008 |
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2012 Journal Article Triheptanoin - a medium chain triglyceride with odd chain fatty acids: a new anaplerotic anticonvulsant treatment?Borges, Karin and Sonnewald, Ursula (2012). Triheptanoin - a medium chain triglyceride with odd chain fatty acids: a new anaplerotic anticonvulsant treatment?. Epilepsy Research, 100 (3), 239-244. doi: 10.1016/j.eplepsyres.2011.05.023 |
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2012 Journal Article Triheptanoin in acute mouse seizure modelsNicola, Thomas K., Willis, Sarah, Sweetman, Lawrence and Borges, Karin (2012). Triheptanoin in acute mouse seizure models. Epilepsy Research, 99 (3), 312-317. doi: 10.1016/j.eplepsyres.2011.12.013 |
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2011 Journal Article Protective effect of the ketogenic diet in Scn1a mutant miceDutton, Stacey B. B., Sawyer, Nikki T., Kalume, Franck, Jumbo-Lucioni, Patricia, Borges, Karin, Catterall, William A. and Escayg, Andrew (2011). Protective effect of the ketogenic diet in Scn1a mutant mice. Epilepsia, 52 (11), 2050-2056. doi: 10.1111/j.1528-1167.2011.03211.x |
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2011 Journal Article The ketogenic diet changes metabolite levels in hippocampal extracellular fluidSamala, Ramakrishna, Klein, Jochen and Borges, Karin (2011). The ketogenic diet changes metabolite levels in hippocampal extracellular fluid. Neurochemistry International, 58 (1), 5-8. doi: 10.1016/j.neuint.2010.10.011 |
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2010 Journal Article Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure modelsWillis, Sarah, Stoll, James, Sweetman, Lawrence and Borges, Karin (2010). Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models. Neurobiology of Disease, 40 (3), 565-572. doi: 10.1016/j.nbd.2010.07.017 |
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2009 Journal Article Quantitative transcriptional neuroanatomy of the rat hippocampus: Evidence for wide-ranging, pathway-specific heterogeneity among three principal cell layersGreene, James G., Borges, Karin and Dingledine, Raymond (2009). Quantitative transcriptional neuroanatomy of the rat hippocampus: Evidence for wide-ranging, pathway-specific heterogeneity among three principal cell layers. Hippocampus, 19 (3), 253-264. doi: 10.1002/hipo.20502 |
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2009 Journal Article Eicosapentaenoic and docosahexaenoic acids are not anticonvulsant or neuroprotective in acute mouse seizure modelsWillis, Sarah, Samala, Ramakrishna, Rosenberger, Thad A. and Borges, Karin (2009). Eicosapentaenoic and docosahexaenoic acids are not anticonvulsant or neuroprotective in acute mouse seizure models. Epilepsia, 50 (1), 138-142. doi: 10.1111/j.1528-1167.2008.01722.x |
