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2024

Journal Article

Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxemia in sleep apnea patients

Pahari, Purbanka, Korkalainen, Henri, Arnardóttir, Erna Sif, Islind, Anna Sigridur, August, Elias, Oksenberg, Arie, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2024). Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxemia in sleep apnea patients. ERJ Open Research, 10 (4) 01051-2023, 1-12. doi: 10.1183/23120541.01051-2023

Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxemia in sleep apnea patients

2024

Journal Article

Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations

Jäntti, Jiri, Joenathan, Anisha, Fugazzola, Maria, Tuppurainen, Juuso, Honkanen, Juuso T. J., Töyräs, Juha, van Weeren, René, Snyder, Brian D., Grinstaff, Mark W., Matikka, Hanna and Mäkelä, Janne T.A. (2024). Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations. Osteoarthritis and Cartilage, 32 (3), 299-309. doi: 10.1016/j.joca.2023.11.020

Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations

2024

Journal Article

Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients

Ebrahimian, Serajeddin, Sillanmäki, Saara, Hietakoste, Salla, Kulkas, Antti, Töyräs, Juha, Bailon, Raquel, Hernando, David, Lombardi, Carolina, Grote, Ludger, Bonsignore, Maria R, Saaresranta, Tarja, Pépin, Jean-Louis, Leppänen, Timo and Kainulainen, Samu (2024). Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients. American Journal of Physiology-Heart and Circulatory Physiology, 326 (5), H1094-H1104. doi: 10.1152/ajpheart.00760.2023

Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients

2024

Journal Article

Variation in the photoplethysmogram response to arousal from sleep depending on the cause of arousal and the presence of desaturation

Luukinen, Mieli, Pitkänen, Henna, Leppänen, Timo, Töyräs, Juha, Islind, Anna Sigridur, Kainulainen, Samu and Korkalainen, Henri (2024). Variation in the photoplethysmogram response to arousal from sleep depending on the cause of arousal and the presence of desaturation. IEEE Journal of Translational Engineering in Health and Medicine, 12, 328-339. doi: 10.1109/jtehm.2024.3349916

Variation in the photoplethysmogram response to arousal from sleep depending on the cause of arousal and the presence of desaturation

2024

Journal Article

Triple contrast computed tomography reveals site‐specific biomechanical differences in the human knee joint—A proof of concept study

Orava, Heta, Paakkari, Petri, Jäntti, Jiri, Honkanen, Miitu K. M., Honkanen, Juuso T. J., Virén, Tuomas, Joenathan, Anisha, Tanska, Petri, Korhonen, Rami K., Grinstaff, Mark W., Töyräs, Juha and Mäkelä, Janne T. A. (2024). Triple contrast computed tomography reveals site‐specific biomechanical differences in the human knee joint—A proof of concept study. Journal of Orthopaedic Research, 42 (2), 415-424. doi: 10.1002/jor.25683

Triple contrast computed tomography reveals site‐specific biomechanical differences in the human knee joint—A proof of concept study

2024

Journal Article

Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia

Hietakoste, Salla, Armañac-Julián, Pablo, Karhu, Tuomas, Bailón, Raquel, Sillanmäki, Saara, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2024). Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia. IEEE Transactions on Biomedical Engineering, 71 (1), 326-333. doi: 10.1109/tbme.2023.3300079

Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia

2023

Journal Article

Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index

Pitkänen, Minna, Nath, Rajdeep Kumar, Korkalainen, Henri, Nikkonen, Sami, Mahamid, Alaa, Oksenberg, Arie, Duce, Brett, Töyräs, Juha, Kainulainen, Samu and Leppänen, Timo (2023). Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index. Sleep Advances, 5 (1) zpad054, 1-9. doi: 10.1093/sleepadvances/zpad054

Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index

2023

Journal Article

Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrix

Kafian-Attari, Iman, Nippolainen, Ervin, Bergmann, Florian, George, Akuroma, Paakkari, Petri, Mirhashemi, Arash, Foschum, Florian, Kienle, Alwin, Töyräs, Juha and Afara, Isaac O. (2023). Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrix. Journal of biomedical optics, 28 (12) 125003, 1-16. doi: 10.1117/1.JBO.28.12.125003

Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrix

2023

Journal Article

3D T<sub>1</sub> relaxation time measurements in an equine model of subtle post‐traumatic osteoarthritis using MB‐SWIFT

Pala, Swetha, Hänninen, Nina E., Mohammadi, Ali, Ebrahimi, Mohammadhossein, te Moller, Nikae C. R., Brommer, Harold, René van Weeren, P., Mäkelä, Janne T. A., Korhonen, Rami K., Afara, Isaac O., Töyräs, Juha, Mikkonen, Santtu, Nissi, Mikko J. and Nykänen, Olli (2023). 3D T1 relaxation time measurements in an equine model of subtle post‐traumatic osteoarthritis using MB‐SWIFT. Journal of Orthopaedic Research, 41 (12), 2657-2666. doi: 10.1002/jor.25629

3D T<sub>1</sub> relaxation time measurements in an equine model of subtle post‐traumatic osteoarthritis using MB‐SWIFT

2023

Journal Article

Review and perspective on sleep-disordered breathing research and translation to clinics

Korkalainen, Henri, Kainulainen, Samu, Islind, Anna Sigridur, Óskarsdóttir, María, Strassberger, Christian, Nikkonen, Sami, Töyräs, Juha, Kulkas, Antti, Grote, Ludger, Hedner, Jan, Sund, Reijo, Hrubos-Strom, Harald, Saavedra, Jose M., Ólafsdóttir, Kristín Anna, Ágústsson, Jón S., Terrill, Philip I., McNicholas, Walter T., Arnardóttir, Erna Sif, Leppänen, Timo and On behalf of SLEEP REVOLUTION (2023). Review and perspective on sleep-disordered breathing research and translation to clinics. Sleep Medicine Reviews, 73 101874, 1-12. doi: 10.1016/j.smrv.2023.101874

Review and perspective on sleep-disordered breathing research and translation to clinics

2023

Journal Article

Refractive index of human articular cartilage varies with tissue structure and composition

Khan, Bilour, Nippolainen, Ervin, Shahini, Fatemeh, Torniainen, Jari, Mikkonen, Santtu, Nonappa, Popov, Alexey, Töyräs, Juha and Afara, Isaac (2023). Refractive index of human articular cartilage varies with tissue structure and composition. Journal of the Optical Society of America A, 40 (12), 2205-2214. doi: 10.1364/josaa.498722

Refractive index of human articular cartilage varies with tissue structure and composition

2023

Journal Article

Self-applied somnography: technical feasibility of electroencephalography and electro-oculography signal characteristics in sleep staging of suspected sleep-disordered adults

Rusanen, Matias, Korkalainen, Henri, Gretarsdottir, Heidur, Siilak, Tiina, Olafsdottir, Kristin Anna, Töyräs, Juha, Myllymaa, Sami, Arnardottir, Erna Sif, Leppänen, Timo and Kainulainen, Samu (2023). Self-applied somnography: technical feasibility of electroencephalography and electro-oculography signal characteristics in sleep staging of suspected sleep-disordered adults. Journal of Sleep Research, 33 (2) e13977, e13977. doi: 10.1111/jsr.13977

Self-applied somnography: technical feasibility of electroencephalography and electro-oculography signal characteristics in sleep staging of suspected sleep-disordered adults

2023

Journal Article

Impact of experimental setup parameters on measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands

Kafian-Attari, Iman, Nippolainen, Ervin, Bergmann, Florian, Mirhashemi, Arash, Pakkari, Petri, Foschum, Florian, Kienle, Alwin, Töyräs, Juha and Afara, Isaac (2023). Impact of experimental setup parameters on measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands. Biomedical Optics Express, 14 (7), 3397-3412. doi: 10.1364/boe.488801

Impact of experimental setup parameters on measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands

2023

Journal Article

Oxygen resaturation rate is significantly associated with objectively assessed excessive daytime sleepiness in suspected obstructive sleep apnoea patients

Howarth, Timothy P., Karhu, Tuomas, Kainulainen, Samu, Chen, Xin, Mahamid, Alaa, Töyräs, Juha and Leppänen, Timo (2023). Oxygen resaturation rate is significantly associated with objectively assessed excessive daytime sleepiness in suspected obstructive sleep apnoea patients. Sleep Medicine, 107, 171-178. doi: 10.1016/j.sleep.2023.04.027

Oxygen resaturation rate is significantly associated with objectively assessed excessive daytime sleepiness in suspected obstructive sleep apnoea patients

2023

Journal Article

Characterisation of cartilage damage via fusing mid-infrared, near-infrared, and Raman spectroscopic data

Shaikh, Rubina, Tafintseva, Valeria, Nippolainen, Ervin, Virtanen, Vesa, Solheim, Johanne, Zimmermann, Boris, Saarakkala, Simo, Töyräs, Juha, Kohler, Achim and Afara, Isaac O. (2023). Characterisation of cartilage damage via fusing mid-infrared, near-infrared, and Raman spectroscopic data. Journal of Personalized Medicine, 13 (7) 1036, 1036. doi: 10.3390/jpm13071036

Characterisation of cartilage damage via fusing mid-infrared, near-infrared, and Raman spectroscopic data

2023

Journal Article

Visible and near-infrared spectroscopy enables differentiation of normal and early osteoarthritic human knee joint articular cartilage

Linus, Awuniji, Tanska, Petri, Sarin, Jaakko K., Nippolainen, Ervin, Tiitu, Virpi, Mäkelä, Janne. T. A., Töyräs, Juha, Korhonen, Rami K., Mononen, Mika E. and Afara, Isaac O. (2023). Visible and near-infrared spectroscopy enables differentiation of normal and early osteoarthritic human knee joint articular cartilage. Annals of Biomedical Engineering, 51 (10), 2245-2257. doi: 10.1007/s10439-023-03261-7

Visible and near-infrared spectroscopy enables differentiation of normal and early osteoarthritic human knee joint articular cartilage

2023

Journal Article

Raman spectroscopy and machine learning enables estimation of articular cartilage structural, compositional, and functional properties

Shehata, Eslam, Nippolainen, Ervin, Shaikh, Rubina, Ronkainen, Ari-Petteri, Töyräs, Juha, Sarin, Jaakko K. and Afara, Isaac O. (2023). Raman spectroscopy and machine learning enables estimation of articular cartilage structural, compositional, and functional properties. Annals of Biomedical Engineering, 51 (10), 2301-2312. doi: 10.1007/s10439-023-03271-5

Raman spectroscopy and machine learning enables estimation of articular cartilage structural, compositional, and functional properties

2023

Journal Article

Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance

Pahari, Purbanka, Korkalainen, Henri, Karhu, Tuomas, Rissanen, Marika, Arnardottir, Erna Sif, Hrubos‐Strøm, Harald, Duce, Brett, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2023). Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance. Journal of Sleep Research, 32 (3) e13803, 1-9. doi: 10.1111/jsr.13803

Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance

2023

Journal Article

A multi-objective based scheduling framework for effective resource utilization in cloud computing

Reddy, Pillareddy Vamsheedhar and Reddy, Karri Ganesh (2023). A multi-objective based scheduling framework for effective resource utilization in cloud computing. IEEE Access, 11, 37178-37193. doi: 10.1109/access.2023.3266294

A multi-objective based scheduling framework for effective resource utilization in cloud computing

2023

Journal Article

Deep learning-based algorithm accurately classifies sleep stages in preadolescent children with sleep-disordered breathing symptoms and age-matched controls

Somaskandhan, Pranavan, Leppänen, Timo, Terrill, Philip I., Sigurdardottir, Sigridur, Arnardottir, Erna Sif, Ólafsdóttir, Kristín A., Serwatko, Marta, Sigurðardóttir, Sigurveig Þ., Clausen, Michael, Töyräs, Juha and Korkalainen, Henri (2023). Deep learning-based algorithm accurately classifies sleep stages in preadolescent children with sleep-disordered breathing symptoms and age-matched controls. Frontiers in Neurology, 14 1162998, 1-12. doi: 10.3389/fneur.2023.1162998

Deep learning-based algorithm accurately classifies sleep stages in preadolescent children with sleep-disordered breathing symptoms and age-matched controls