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2025

Conference Publication

Machine Learning-Based Classification of Early Osteoarthritis Using Contrast-Enhanced Computed Tomography

Paakkari, Petri, Inkinen, Satu I., Jäntti, Jiri, Tuppurainen, Juuso, Nurmirinta, Teemu A., Nieminen, Miika T., Weeren, René van, Snyder, Brian, Töyräs, Juha, Honkanen, Miitu, Grinstaff, Mark, Tanska, Petri, Mäkelä, Janne and Honkanen, Juuso T. (2025). Machine Learning-Based Classification of Early Osteoarthritis Using Contrast-Enhanced Computed Tomography. OARSI 2025 World Congress on Osteoarthritis, Incheon, South Korea, 24-27 April 2025. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2025.03.014

Machine Learning-Based Classification of Early Osteoarthritis Using Contrast-Enhanced Computed Tomography

2025

Journal Article

Retrospective validation of automatic sleep analysis with grey areas model for human‐in‐the‐loop scoring approach

Rusanen, Matias, Jouan, Gabriel, Huttunen, Riku, Nikkonen, Sami, Sigurðardóttir, Sigríður, Töyräs, Juha, Duce, Brett, Myllymaa, Sami, Arnardottir, Erna Sif, Leppänen, Timo, Islind, Anna Sigridur, Kainulainen, Samu and Korkalainen, Henri (2025). Retrospective validation of automatic sleep analysis with grey areas model for human‐in‐the‐loop scoring approach. Journal of Sleep Research, 34 (3) e14362, 1-13. doi: 10.1111/jsr.14362

Retrospective validation of automatic sleep analysis with grey areas model for human‐in‐the‐loop scoring approach

2025

Journal Article

Relationships between human patellar tendon and tibial cartilage viscoelastic properties in osteoarthritic knees: an exploratory investigation

Kositsky, Adam, Linus, Awuniji, Stenroth, Lauri, Nippolainen, Ervin, Kröger, Heikki, Töyräs, Juha, Mäkelä, Janne T.A., Liukkonen, Mimmi K., Tanska, Petri, Afara, Isaac O., Mononen, Mika E. and Korhonen, Rami K. (2025). Relationships between human patellar tendon and tibial cartilage viscoelastic properties in osteoarthritic knees: an exploratory investigation. Journal of Biomechanics, 189 112772, 112772-189. doi: 10.1016/j.jbiomech.2025.112772

Relationships between human patellar tendon and tibial cartilage viscoelastic properties in osteoarthritic knees: an exploratory investigation

2025

Journal Article

Non-Destructive Assessment of Tissue Engineered Cartilage Maturity Using Visible and Near Infrared Spectroscopy Combined with Machine Learning

Elkadi, Omar Anwar, Abinzano, Florencia, Nippolainen, Ervin, González, Ona Bach, Töyräs, Juha, Levato, Riccardo, Malda, Jos and Afara, Isaac O. (2025). Non-Destructive Assessment of Tissue Engineered Cartilage Maturity Using Visible and Near Infrared Spectroscopy Combined with Machine Learning. Biosensors and Bioelectronics, 286 117587, 117587-286. doi: 10.1016/j.bios.2025.117587

Non-Destructive Assessment of Tissue Engineered Cartilage Maturity Using Visible and Near Infrared Spectroscopy Combined with Machine Learning

2025

Conference Publication

Viscoelastic Properties Of Human Collateral Knee Ligaments Are Related And Altered In Osteoarthritis

Kositsky, Adam, Gheisari, Anahita, Karjalainen, Ville-Pauli, Virtanen, Vesa, Nippolainen, Ervin, Linus, Awuniji, Kröger, Heikki, Töyräs, Juha, Tanska, Petri, Saarakkala, Simo, Mononen, Mika, Afara, Isaac, Korhonen, Rami K. and Finnilä, Mikko (2025). Viscoelastic Properties Of Human Collateral Knee Ligaments Are Related And Altered In Osteoarthritis. OARSI 2025 World Congress on Osteoarthritis, Incheon, South Korea, 24-27 April 2025. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2025.02.022

Viscoelastic Properties Of Human Collateral Knee Ligaments Are Related And Altered In Osteoarthritis

2025

Conference Publication

Towards Automatic Segmentation Of Cartilage In Contrast-enhanced Computed Tomography

Orava, Heta, Myller, Katariina A., Paakkari, Petri, Jäntti, Jiri, Honkanen, Miitu, Honkanen, Juuso T., Virén, Tuomas, Grinstaff, Mark, Töyräs, Juha, Väänänen, Sami P. and Mäkelä, Janne (2025). Towards Automatic Segmentation Of Cartilage In Contrast-enhanced Computed Tomography. OARSI 2025 World Congress on Osteoarthritis, Incheon, South Korea, 24-27 April 2025. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2025.02.404

Towards Automatic Segmentation Of Cartilage In Contrast-enhanced Computed Tomography

2025

Journal Article

Dual-Contrast Agent with Nanoparticle and Molecular Components in Photon-Counting Computed Tomography: Assessing Articular Cartilage Health

Paakkari, Petri, Inkinen, Satu I., Jäntti, Jiri, Tuppurainen, Juuso, Fugazzola, Maria C., Joenathan, Anisha, Ylisiurua, Sampo, Nieminen, Miika T., Kröger, Heikki, Mikkonen, Santtu, van Weeren, René, Snyder, Brian D., Töyräs, Juha, Honkanen, Miitu K. M., Matikka, Hanna, Grinstaff, Mark W., Honkanen, Juuso T. J. and Mäkelä, Janne T. A. (2025). Dual-Contrast Agent with Nanoparticle and Molecular Components in Photon-Counting Computed Tomography: Assessing Articular Cartilage Health. Annals of Biomedical Engineering, 53 (6), 1-16. doi: 10.1007/s10439-025-03715-0

Dual-Contrast Agent with Nanoparticle and Molecular Components in Photon-Counting Computed Tomography: Assessing Articular Cartilage Health

2025

Journal Article

Machine learning approaches for the fusion of near-infrared, mid-infrared, and Raman data to identify cartilage degradation in human osteochondral plugs

Tafintseva, Valeria, Nippolainen, Ervin, Virtanen, Vesa, Solheim, Johanne Heitmann, Zimmermann, Boris, Saarakkala, Simo, Kröger, Heikki, Kohler, Achim, Töyräs, Juha, Afara, Isaac O. and Shaikh, Rubina (2025). Machine learning approaches for the fusion of near-infrared, mid-infrared, and Raman data to identify cartilage degradation in human osteochondral plugs. Applied Spectroscopy, 79 (3), 385-395. doi: 10.1177/00037028241285583

Machine learning approaches for the fusion of near-infrared, mid-infrared, and Raman data to identify cartilage degradation in human osteochondral plugs

2025

Conference Publication

Heart rate variability: an early biomarker of cystic fibrosis exacerbation

Mattison, G., Dobbins, C., Smith, D., Reid, D., Canfell, O., Sullivan, C., Toyras, J., Okano, S., Pelecanos, A., Hartel, G. and Forrester, D. (2025). Heart rate variability: an early biomarker of cystic fibrosis exacerbation. TSANZSRS Annual Scientific meeting 2025, Adelaide, SA, Australia, 21-25 March 2025. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/imj.70003

Heart rate variability: an early biomarker of cystic fibrosis exacerbation

2025

Journal Article

The human patellar tendon is mechanically homogenous at its mid-substance

Kositsky, Adam, Stenroth, Lauri, Nippolainen, Ervin, Torniainen, Jari, Mäkelä, Janne T.A., Paakkari, Petri, Paakkonen, Tommi, Kröger, Heikki, Töyräs, Juha, Afara, Isaac O. and Korhonen, Rami K. (2025). The human patellar tendon is mechanically homogenous at its mid-substance. Journal of the Mechanical Behavior of Biomedical Materials, 163 106875, 1-10. doi: 10.1016/j.jmbbm.2024.106875

The human patellar tendon is mechanically homogenous at its mid-substance

2025

Journal Article

Hybrid discrete and finite element analysis enables fast evaluation of hip joint cartilage mechanical response

Venäläinen, Mikko S., Li, Mao, Töyräs, Juha, Korhonen, Rami K., Fripp, Jurgen, Crozier, Stuart, Chandra, Shekhar S. and Engstrom, Craig (2025). Hybrid discrete and finite element analysis enables fast evaluation of hip joint cartilage mechanical response. Journal of Biomechanics, 182 112568, 1-6. doi: 10.1016/j.jbiomech.2025.112568

Hybrid discrete and finite element analysis enables fast evaluation of hip joint cartilage mechanical response

2025

Journal Article

Community prevalence of positional obstructive sleep apnea

Duce, Brett L., Kulkas, Antti E., Leppänen, Timo T., Oksenberg, Arie, Töyräs, Juha and Hukins, Craig A. (2025). Community prevalence of positional obstructive sleep apnea. Journal of Clinical Sleep Medicine, 21 (5), 875-882. doi: 10.5664/jcsm.11584

Community prevalence of positional obstructive sleep apnea

2025

Journal Article

Arousal burden is highest in supine sleeping position and during light sleep

Pitkänen, Minna, Huovinen, Juho, Rissanen, Marika, Pitkänen, Henna, Kainulainen, Samu, Penzel, Thomas, Fanfulla, Francesco, Anttalainen, Ulla, Saaresranta, Tarja, Grote, Ludger, Hedner, Jan, Staats, Richard, Duce, Brett, Töyräs, Juha, Oksenberg, Arie and Leppänen, Timo (2025). Arousal burden is highest in supine sleeping position and during light sleep. Journal of Clinical Sleep Medicine, 21 (2), 337-344. doi: 10.5664/jcsm.11398

Arousal burden is highest in supine sleeping position and during light sleep

2025

Journal Article

The Relationship Between the Optical Properties of Articular Cartilage and the Biomechanical Parameters of the Tissue

Kafian-Attari, Iman, Ebrahimi, Mohammad, Nippolainen, Ervin, Mirhashemi, Arash, Paakkari, Petri, Bergmann, Florian, Foschum, Florian, Kienle, Alwin, Toyras, Juha and Afara, Isaac (2025). The Relationship Between the Optical Properties of Articular Cartilage and the Biomechanical Parameters of the Tissue. Journal of Biophotonics, 18 (4) e202400460, e202400460. doi: 10.1002/jbio.202400460

The Relationship Between the Optical Properties of Articular Cartilage and the Biomechanical Parameters of the Tissue

2025

Journal Article

Orientation-Independent T2 Mapping Enhances MRI-Based Cartilage Characterization

Leskinen, Henri P. P., Tuppurainen, Juuso, Jäntti, Jiri, Mäkelä, Janne T. A., Nippolainen, Ervin, Afara, Isaac O., Töyräs, Juha, Nykänen, Olli and Nissi, Mikko J. (2025). Orientation-Independent T2 Mapping Enhances MRI-Based Cartilage Characterization. Annals of Biomedical Engineering. doi: 10.1007/s10439-025-03774-3

Orientation-Independent T2 Mapping Enhances MRI-Based Cartilage Characterization

2025

Journal Article

EXPLORING THE RELATIONSHIP BETWEEN LIGAMENT MICROSTRUCTURE AND MECHANICS IN OA-AFFECTED HUMAN KNEES

Gheisari, A., Kositsky, A., Karjalainen, V.-P., Gupta, S. Das, Virtanen, V., Nippolainen, E., Kröger, H., Töyräs, J., Saarakkala, S., Afara, I.O., Korhonen, R.K. and Finnilä, M.A.J. (2025). EXPLORING THE RELATIONSHIP BETWEEN LIGAMENT MICROSTRUCTURE AND MECHANICS IN OA-AFFECTED HUMAN KNEES. Osteoarthritis Imaging, 5 100287, 100287. doi: 10.1016/j.ostima.2025.100287

EXPLORING THE RELATIONSHIP BETWEEN LIGAMENT MICROSTRUCTURE AND MECHANICS IN OA-AFFECTED HUMAN KNEES

2024

Journal Article

Nocturnal short-term HRV reflects impaired daytime vigilance better than overnight HRV in suspected OSA patients

Hietakoste, Salla, Karhu, Tuomas, Lombardi, Carolina, Armañac-Julián, Pablo, Bailón, Raquel, Duce, Brett, Sillanmäki, Saara, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2024). Nocturnal short-term HRV reflects impaired daytime vigilance better than overnight HRV in suspected OSA patients. Sleep, 48 (4) zsae282. doi: 10.1093/sleep/zsae282

Nocturnal short-term HRV reflects impaired daytime vigilance better than overnight HRV in suspected OSA patients

2024

Journal Article

Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage

Paakkari, Petri, Inkinen, Satu I., Mohammadi, Ali, Nieminen, Miika T., Joenathan, Anisha, Grinstaff, Mark W., Töyräs, Juha, Mäkelä, Janne T. A. and Honkanen, Juuso T. J. (2024). Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage. Scientific Reports, 14 (1) 29956, 1-14. doi: 10.1038/s41598-024-78237-1

Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage

2024

Journal Article

Temporal and sleep stage‐dependent agreement in manual scoring of respiratory events

Pitkänen, Minna, Pitkänen, Henna, Nath, Rajdeep Kumar, Nikkonen, Sami, Kainulainen, Samu, Korkalainen, Henri, Ólafsdóttir, Kristín Anna, Arnardottir, Erna Sif, Sigurdardottir, Sigridur, Penzel, Thomas, Fanfulla, Francesco, Anttalainen, Ulla, Saaresranta, Tarja, Grote, Ludger, Hedner, Jan, Staats, Richard, Töyräs, Juha and Leppänen, Timo (2024). Temporal and sleep stage‐dependent agreement in manual scoring of respiratory events. Journal of Sleep Research, 34 (3) e14391, e14391. doi: 10.1111/jsr.14391

Temporal and sleep stage‐dependent agreement in manual scoring of respiratory events

2024

Conference Publication

Worsening hypoxic load impairs cardiorespiratory coupling

Hietakoste, Salla, Armañac-Julián, Pablo, Karhu, Tuomas, Bailón, Raquel, Sillanmäki, Saara, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2024). Worsening hypoxic load impairs cardiorespiratory coupling. 2024 13th Conference of the European Study Group on Cardiovascular Oscillations: Physiologically-Guided Signal Processing of Cardiovascular and Cerebrovascular Oscillations, ESGCO 2024, Zaragoza, Spain, 23-25 October 2024. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/esgco63003.2024.10767029

Worsening hypoxic load impairs cardiorespiratory coupling