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2025 Journal Article Hybrid discrete and finite element analysis enables fast evaluation of hip joint cartilage mechanical responseVenäläinen, Mikko S., Li, Mao, Töyräs, Juha, Korhonen, Rami K., Fripp, Jurgen, Crozier, Stuart, Chandra, Shekhar S. and Engstrom, Craig (2025). Hybrid discrete and finite element analysis enables fast evaluation of hip joint cartilage mechanical response. Journal of Biomechanics, 182 112568, 1-6. doi: 10.1016/j.jbiomech.2025.112568 |
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2025 Journal Article Arousal burden is highest in supine sleeping position and during light sleepPitkänen, Minna, Huovinen, Juho, Rissanen, Marika, Pitkänen, Henna, Kainulainen, Samu, Penzel, Thomas, Fanfulla, Francesco, Anttalainen, Ulla, Saaresranta, Tarja, Grote, Ludger, Hedner, Jan, Staats, Richard, Duce, Brett, Töyräs, Juha, Oksenberg, Arie and Leppänen, Timo (2025). Arousal burden is highest in supine sleeping position and during light sleep. Journal of Clinical Sleep Medicine, 21 (2), 337-344. doi: 10.5664/jcsm.11398 |
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2025 Journal Article EXPLORING THE RELATIONSHIP BETWEEN LIGAMENT MICROSTRUCTURE AND MECHANICS IN OA-AFFECTED HUMAN KNEESGheisari, A., Kositsky, A., Karjalainen, V.-P., Gupta, S. Das, Virtanen, V., Nippolainen, E., Kröger, H., Töyräs, J., Saarakkala, S., Afara, I.O., Korhonen, R.K. and Finnilä, M.A.J. (2025). EXPLORING THE RELATIONSHIP BETWEEN LIGAMENT MICROSTRUCTURE AND MECHANICS IN OA-AFFECTED HUMAN KNEES. Osteoarthritis Imaging, 5 100287, 100287. doi: 10.1016/j.ostima.2025.100287 |
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2025 Conference Publication Assessment of Joint Integrity via Near-Infrared Spectroscopic Estimation of Biomarkers in Synovial Fluid: A Potential Tool for Early Detection of OsteoarthritisShahini, Fatemeh, Oikari, Sanna, Sadeesh, Nithin, Nippolainen, Ervin, Brommer, Harold, Töyräs, Juha, Nieminen, Petteri and Afara, Isaac O. (2025). Assessment of Joint Integrity via Near-Infrared Spectroscopic Estimation of Biomarkers in Synovial Fluid: A Potential Tool for Early Detection of Osteoarthritis. Washington, D.C.: Optica Publishing Group. doi: 10.1364/ecbo.2025.w1a.5 |
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2024 Journal Article Nocturnal short-term HRV reflects impaired daytime vigilance better than overnight HRV in suspected OSA patientsHietakoste, Salla, Karhu, Tuomas, Lombardi, Carolina, Armañac-Julián, Pablo, Bailón, Raquel, Duce, Brett, Sillanmäki, Saara, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2024). Nocturnal short-term HRV reflects impaired daytime vigilance better than overnight HRV in suspected OSA patients. Sleep, 48 (4) zsae282. doi: 10.1093/sleep/zsae282 |
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2024 Journal Article Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilagePaakkari, Petri, Inkinen, Satu I., Mohammadi, Ali, Nieminen, Miika T., Joenathan, Anisha, Grinstaff, Mark W., Töyräs, Juha, Mäkelä, Janne T. A. and Honkanen, Juuso T. J. (2024). Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage. Scientific Reports, 14 (1) 29956, 1-14. doi: 10.1038/s41598-024-78237-1 |
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2024 Journal Article Temporal and sleep stage‐dependent agreement in manual scoring of respiratory eventsPitkänen, Minna, Pitkänen, Henna, Nath, Rajdeep Kumar, Nikkonen, Sami, Kainulainen, Samu, Korkalainen, Henri, Ólafsdóttir, Kristín Anna, Arnardottir, Erna Sif, Sigurdardottir, Sigridur, Penzel, Thomas, Fanfulla, Francesco, Anttalainen, Ulla, Saaresranta, Tarja, Grote, Ludger, Hedner, Jan, Staats, Richard, Töyräs, Juha and Leppänen, Timo (2024). Temporal and sleep stage‐dependent agreement in manual scoring of respiratory events. Journal of Sleep Research, 34 (3) e14391, e14391. doi: 10.1111/jsr.14391 |
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2024 Conference Publication Worsening hypoxic load impairs cardiorespiratory couplingHietakoste, Salla, Armañac-Julián, Pablo, Karhu, Tuomas, Bailón, Raquel, Sillanmäki, Saara, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2024). Worsening hypoxic load impairs cardiorespiratory coupling. 2024 13th Conference of the European Study Group on Cardiovascular Oscillations: Physiologically-Guided Signal Processing of Cardiovascular and Cerebrovascular Oscillations, ESGCO 2024, Zaragoza, Spain, 23-25 October 2024. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/esgco63003.2024.10767029 |
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2024 Conference Publication O004 Incorporating arousals into sleep vs. wakefulness classification outperforms traditional binary classification at 1-second epoch resolutionSomaskandhan, P., Korkalainen, H., Leppänen, T., Töyräs, J., Melehan, K., Wilson, D., Ruehland, W., Mann, D. and Terrill, P. (2024). O004 Incorporating arousals into sleep vs. wakefulness classification outperforms traditional binary classification at 1-second epoch resolution. Sleep DownUnder 2024, Gold Coast, QLD Australia, 16-19 October 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/sleepadvances/zpae070.004 |
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2024 Conference Publication Ventilatory burden predicts change in self‑reported sleepiness following continuous positive airway pressure treatment in obstructive sleep apnoeaStaykov, E., Mann, D., Duce, B., Kainulainen, S., Leppänen, T., Töyräs, J., Azarbarzin, A., Sands, S. and Terrill, P. (2024). Ventilatory burden predicts change in self‑reported sleepiness following continuous positive airway pressure treatment in obstructive sleep apnoea. 2024 Australasian Sleep Association, Gold Coast, QLD Australia, 16-19 October 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/sleepadvances/zpae070.090 |
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2024 Journal Article An automated and robust tool for musculoskeletal and finite element modeling of the knee jointEsrafilian, Amir, Chandra, Shekhar S., Gatti, Anthony A., Nissi, Mikko, Mustonen, Anne-Mari, Saisanen, Laura, Reijonen, Jusa, Nieminen, Petteri, Julkunen, Petro, Toyras, Juha, Saxby, David J., Lloyd, David G. and Korhonen, Rami K. (2024). An automated and robust tool for musculoskeletal and finite element modeling of the knee joint. IEEE Transactions on Biomedical Engineering, 72 (1), 1-13. doi: 10.1109/tbme.2024.3438272 |
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2024 Journal Article Relationship between depth-wise refractive index and biomechanical properties of human articular cartilageKhan, Bilour, Nippolainen, Ervin, Shahini, Fatemeh, Nonappa,, Popov, Alexey, Töyräs, Juha and Afara, Isaac O. (2024). Relationship between depth-wise refractive index and biomechanical properties of human articular cartilage. Journal of biomedical optics, 29 (9) 095003, 095003. doi: 10.1117/1.JBO.29.9.095003 |
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2024 Journal Article “An excellent servant but a terrible master”: understanding the value of wearables for self-management in people with cystic fibrosis and their healthcare providers – a qualitative studyMattison, Graeme, Canfell, Oliver J., Smith, Daniel, Forrester, Doug, Reid, David, Töyräs, Juha and Dobbins, Chelsea (2024). “An excellent servant but a terrible master”: understanding the value of wearables for self-management in people with cystic fibrosis and their healthcare providers – a qualitative study. International Journal of Medical Informatics, 189 105532, 105532. doi: 10.1016/j.ijmedinf.2024.105532 |
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2024 Journal Article Estimation of photon path length and penetration depth in articular cartilage zonal architecture over the therapeutic windowKafian-Attari, I., Nippolainen, E., Bergmann, F., George, A., Paakkari, P., Mirhashemi, A., Foschum, F., Kienle, A., Toyras, J. and Afara, I. O. (2024). Estimation of photon path length and penetration depth in articular cartilage zonal architecture over the therapeutic window. IEEE Transactions on Biomedical Engineering, 71 (8), 2300-2310. doi: 10.1109/TBME.2024.3368012 |
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2024 Journal Article Infrared spectroscopy can differentiate between cartilage injury models: implication for assessment of cartilage integrityShahini, Fatemeh, Oskouei, Soroush, Nippolainen, Ervin, Mohammadi, Ali, Sarin, Jaakko K., Moller, Nikae C. R. te, Brommer, Harold, Shaikh, Rubina, Korhonen, Rami K., van Weeren, P. René, Töyräs, Juha and Afara, Isaac O. (2024). Infrared spectroscopy can differentiate between cartilage injury models: implication for assessment of cartilage integrity. Annals of Biomedical Engineering, 52 (9), 2521-2533. doi: 10.1007/s10439-024-03540-x |
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2024 Journal Article Laser-irradiating infrared attenuated total reflection spectroscopy of articular cartilage: potential and challenges for diagnosing osteoarthritisKrebs, P., Nägele, M., Fomina, P., Virtanen, V., Nippolainen, E., Shaikh, R., Afara, I. O., Töyräs, J., Usenov, I., Sakharova, T., Artyushenko, V., Tafintseva, V., Solheim, J.H., Zimmermann, B., Kohler, A., König, O., Saarakkala, S. and Mizaikoff, B. (2024). Laser-irradiating infrared attenuated total reflection spectroscopy of articular cartilage: potential and challenges for diagnosing osteoarthritis. Osteoarthritis and Cartilage Open, 6 (2) 100466, 100466. doi: 10.1016/j.ocarto.2024.100466 |
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2024 Journal Article Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apneaChen, Xin, Leppänen, Timo, Kainulainen, Samu, Howarth, Timothy P., Oksenberg, Arie, Töyräs, Juha, Terrill, Philip I. and Korkalainen, Henri (2024). Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apnea. Journal of Clinical Sleep Medicine, 20 (10), 1595-1606. doi: 10.5664/jcsm.11198 |
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2024 Journal Article Site-specific elastic and viscoelastic biomechanical properties of healthy and osteoarthritic human knee joint articular cartilageLinus, Awuniji, Tanska, Petri, Nippolainen, Ervin, Tiitu, Virpi, Töyras, Juha, Korhonen, Rami K., Afara, Isaac O. and Mononen, Mika E. (2024). Site-specific elastic and viscoelastic biomechanical properties of healthy and osteoarthritic human knee joint articular cartilage. Journal of Biomechanics, 169 112135, 112135. doi: 10.1016/j.jbiomech.2024.112135 |
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2024 Journal Article Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apneaPahari, Purbanka, Korkalainen, Henri, Karhu, Tuomas, Arnardottir, Erna Sif, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2024). Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea. Journal of Sleep Research, 33 (2) e13988, e13988. doi: 10.1111/jsr.13988 |
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2024 Journal Article Increased flow limitation during sleep is associated with increased psychomotor vigilance task lapses in individuals with suspected obstructive sleep apneaStaykov, Eric, Mann, Dwayne L., Duce, Brett, Kainulainen, Samu, Leppänen, Timo, Töyräs, Juha, Azarbarzin, Ali, Georgeson, Thomas, Sands, Scott A. and Terrill, Philip I. (2024). Increased flow limitation during sleep is associated with increased psychomotor vigilance task lapses in individuals with suspected obstructive sleep apnea. CHEST, 165 (4), 990-1003. doi: 10.1016/j.chest.2023.11.031 |
