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2009 Journal Article Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acidsMcGeary, Ross P., Vella, Peter, Mak, Jeffery Y. W., Guddat, Luke W. and Schenk, Gerhard (2009). Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids. Bioorganic & Medicinal Chemistry Letters, 19 (1), 163-166. doi: 10.1016/j.bmcl.2008.10.125 |
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2008 Journal Article Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenesHadler, K., Tanifum, E.A., Yip, S.H.-C., Mitic, N., Guddat, L.W., Jackson, C.J., Gahan, L.R., Nguyen, K., Carr, P.D., Ollis, D.L., Hengge, A.C., Larrabee, J.A. and Schenk, G. (2008). Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. Journal of the American Chemical Society, 130 (43), 14129-14138. doi: 10.1021/ja803346w |
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2008 Journal Article Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?Hadler, K.ieran S., Huber, Thomas, Cassady, A. Ian, Weber, Jane, Robinson, Jodie, Burrows, Allan, Kelly, Gregory, Guddat, Luke W., Hume, David A., Schenk, Gerhard and Flanagan, Jack U. (2008). Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?. BMC Research Notes, 1 (1) 78, 1-8. doi: 10.1186/1756-0500-1-78 |
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2008 Journal Article Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preferenceJackson, Colin J., Hadler, Kieran S., Carr, Paul D., Oakley, Aaron J., Yip, Sylvia, Schenk, Gerhard and Ollis, David L. (2008). Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 64 (8), 681-685. doi: 10.1107/S1744309108017600 |
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2008 Journal Article Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligandMirams, Ruth E., Smith, Sarah J., Hadler, Kieran S., Ollis, David L., Schenk, Gerhard and Gahan, Lawrence R. (2008). Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand. Journal of Biological Inorganic Chemistry, 13 (7), 1065-1072. doi: 10.1007/s00775-008-0392-5 |
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2008 Journal Article Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycleSchenk, Gerhard, Elliott, Tristan W., Leung, Eleanor, Carrington, Lyle E., Mitic, Natasa, Gahan, Lawrence R. and Guddat, Luke W. (2008). Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Structural Biology, 8 (6) 6, 1-13. doi: 10.1186/1472-6807-8-6 |
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2008 Journal Article Structural and spectroscopic studies of a model for catechol oxidaseSmith, Sarah J., Noble, Christopher J., Palmer, Randahl C., Hanson, Graeme R., Schenk, Gerhard, Gahan, Lawrence R. and Riley, Mark J. (2008). Structural and spectroscopic studies of a model for catechol oxidase. Journal of Biological Inorganic Chemistry, 13 (4), 499-510. doi: 10.1007/s00775-007-0334-7 |
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2008 Journal Article A structural and catalytic model for zinc phosphoesterasesBuchholz, Rebecca R., Etienne, Morgan E., Dorgelo, Anneke, Mirams, Ruth E., Smith, Sarah J., Chow, Shiao Yun, Hanton, Lyall R., Jameson, Geoffrey B., Schenk, Gerhard and Gahan, Lawrence R. (2008). A structural and catalytic model for zinc phosphoesterases. Dalton Transactions, 2008 (43), 6045-6054. doi: 10.1039/b806391e |
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2008 Journal Article Probing the role of the divalent metal ion in uteroferrin using metal ion replacement and a comparison to isostructural biomimeticsSchenk, Gerhard, Peralta, Rosely A., Batista, Suzana Cimara, Bortoluzzi, Adailton J., Szpoganicz, Bruno, Dick, Andrew K., Herrald, Paul, Hanson, Graeme R., Szilagyi, Robert K., Riley, Mark J., Gahan, Lawrence R. and Neves, Ademir (2008). Probing the role of the divalent metal ion in uteroferrin using metal ion replacement and a comparison to isostructural biomimetics. Journal of Biological Inorganic Chemistry, 13 (1), 139-155. doi: 10.1007/s00775-007-0305-z |
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2008 Journal Article Enzymatic bioremediation: Organophosphate degradation by binuclear metallo-hydrolasesEly, F., Foo, J. L., Jackson, C. J., Gahan, L. R., Ollis, D. L. and Schenk, G. (2008). Enzymatic bioremediation: Organophosphate degradation by binuclear metallo-hydrolases. Current Topics in Biochemical Research, 2008 (9), 63-78. |
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2007 Journal Article Synthesis and characterization of the tetranuclear iron(III) complex of a new asymmetric multidentate ligand. A structural model for purple acid phosphatasesBoudalis, Athanassios K., Aston, Robyn E., Smith, Sarah J., Mirams, Ruth E., Riley, Mark J., Schenk, Gerhard, Blackman, Allan G., Hanton, Lyall R. and Gahan, Lawrence R. (2007). Synthesis and characterization of the tetranuclear iron(III) complex of a new asymmetric multidentate ligand. A structural model for purple acid phosphatases. Dalton Transactions, 2007 (44), 5132-5139. doi: 10.1039/b709293h |
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2007 Journal Article The Reaction Mechanism of the Ga(III)Zn(II) Derivative of Uteroferrin and Corresponding BiomimeticsSmith, S. J., Casellato, A., Hadler, K. S., Mitic, N., Riley, M. J., Bortoluzzi, A. J., Szpoganicz, B., Schenk, G., Neves, A. and Gahan, L. R. (2007). The Reaction Mechanism of the Ga(III)Zn(II) Derivative of Uteroferrin and Corresponding Biomimetics. Journal of Biological Inorganic Chemistry, 12 (8), 1207-1220. doi: 10.1007/s00775-007-0286-y |
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2007 Journal Article Diesterase activity and substrate binding in purple acid phosphatasesCox, R. S., Schenk, G., Mitic, N., Gahan, L. R. and Hengge, A. C. (2007). Diesterase activity and substrate binding in purple acid phosphatases. Journal of The American Chemical Society, 129 (31), 9550-9551. doi: 10.1021/ja072647q |
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2007 Journal Article Using directed evolution to improve the solubility of the C-terminal domain of Escherichia coli aminopeptidase P - Implications for metal binding and protein stabilityLiu, J. W., Hadler, K. S., Schenk, G. and Ollis, D. (2007). Using directed evolution to improve the solubility of the C-terminal domain of Escherichia coli aminopeptidase P - Implications for metal binding and protein stability. FEBS Journal, 274 (18), 4742-4751. doi: 10.1111/j.1742-4658.2007.06022.x |
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2007 Journal Article Kinetic and Spectroscopic Studies of N694C Lipoxygenase: A Probe of the Substrate Activation Mechanism of a Nonheme Ferric EnzymeNeidig, M., Wecksler, A., Schenk, G., Holman, T. and Solomon, E. (2007). Kinetic and Spectroscopic Studies of N694C Lipoxygenase: A Probe of the Substrate Activation Mechanism of a Nonheme Ferric Enzyme. Journal of the American Chemical Society, 129 (24), 7531-7537. doi: 10.1021/ja068503d |
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2007 Journal Article An Unprecedented Fe-III(mu-OH)Zn-II Complex that Mimics the Structural and Functional Properties of Purple Acid PhosphatasesNeves, A., Lanznaster, M., Bortoluzzi, A. J., Peralta, R. A., Casellato, A., Castellano, E. E., Herrald, P., Riley, M. J. and Schenk, G. (2007). An Unprecedented Fe-III(mu-OH)Zn-II Complex that Mimics the Structural and Functional Properties of Purple Acid Phosphatases. Journal of The American Chemical Society, 129 (24), 7486-7487. doi: 10.1021/ja071184l |
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2007 Journal Article Binuclear metallohydrases : emerging drug targetsSchenk, Gerhard (2007). Binuclear metallohydrases : emerging drug targets. Chemistry in Australia, 74 (8), 32-33. |
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2007 Journal Article Structure, function and diversity of plant purple acid phosphatasesLeung, Eleanor W. W., Teixeira, Marina, Guddat, Luke W., Mitić, Natasa and Schenk, Gerhard (2007). Structure, function and diversity of plant purple acid phosphatases. Current Topics in Plant Biology, 8, 21-31. |
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2006 Journal Article Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active siteJackson, Colin J., Carr, Paul D., Kim, Hye-Kyung, Liu, Jian-Wei, Herrald, Paul, Mitic, Natasa, Schenk, Gerhard, Smith, Clyde A. and Ollis, David L. (2006). Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site. Biochemical Journal, 397 (3), 501-508. doi: 10.1042/BJ20060276 |
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2006 Journal Article The Catalytic Mechanisms of Binuclear MetallohydrolasesMitic, Natasa, Smith, Sarah J., Neves, Ademir, Guddat, Luke W., Gahan, Lawrence R. and Schenk, Gerhard (2006). The Catalytic Mechanisms of Binuclear Metallohydrolases. Chemical Reviews, 106 (8), 3338-3363. doi: 10.1021/cr050318f |
