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2015

Journal Article

A pioneering early microreactor concept for ultrafast nitration reactions — Placing the seminal Brennecke and Kobe 1956 contribution into perspective

David Cantillo (2015). A pioneering early microreactor concept for ultrafast nitration reactions — Placing the seminal Brennecke and Kobe 1956 contribution into perspective. Journal of Flow Chemistry, 5 (4), 195-196. doi: 10.1556/1846.2015.00021

A pioneering early microreactor concept for ultrafast nitration reactions — Placing the seminal Brennecke and Kobe 1956 contribution into perspective

2015

Journal Article

Light-induced C-H arylation of (hetero)arenes by in situ generated diazo anhydrides

Cantillo, David, Mateos, Carlos, Rincon, Juan A., de Frutos, Oscar and Oliver Kappe, C. (2015). Light-induced C-H arylation of (hetero)arenes by in situ generated diazo anhydrides. Chemistry: A European Journal, 21 (37), 12894-12898. doi: 10.1002/chem.201502357

Light-induced C-H arylation of (hetero)arenes by in situ generated diazo anhydrides

2015

Journal Article

Homogeneous vs immobilized palladium catalysts for continuous flow cross-coupling chemistry

Cantillo, David and Kappe, C. Oliver (2015). Homogeneous vs immobilized palladium catalysts for continuous flow cross-coupling chemistry. Chimica Oggi, 33 (4), 6-10.

Homogeneous vs immobilized palladium catalysts for continuous flow cross-coupling chemistry

2015

Journal Article

Continuous-flow technology - A tool for the safe manufacturing of active pharmaceutical ingredients

Gutmann, Bernhard, Cantillo, David and Kappe, C. Oliver (2015). Continuous-flow technology - A tool for the safe manufacturing of active pharmaceutical ingredients. Angewandte Chemie (International Edition), 54 (23), 6688-6728. doi: 10.1002/anie.201409318

Continuous-flow technology - A tool for the safe manufacturing of active pharmaceutical ingredients

2015

Journal Article

Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin

Ullen, Andreas, Nusshold, Christoph, Glasnov, Toma, Saf, Robert, Cantillo, David, Eibinger, Gerald, Reicher, Helga, Fauler, Guenter, Bernhart, Eva, Hallstrom, Seth, Kogelnik, Nora, Zangger, Klaus, Kappe, C. Oliver, Malle, Ernst and Sattler, Wolfgang (2015). Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin. Biochemical Pharmacology, 93 (4), 470-481. doi: 10.1016/j.bcp.2014.12.017

Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin

2015

Journal Article

Benchmarking immobilized Di- and triarylphosphine palladium catalysts for continuous-flow cross-coupling reactions: efficiency, durability, and metal leaching studies

Greco, Roberto, Goessler, Walter, Cantillo, David and Kappe, C. Oliver (2015). Benchmarking immobilized Di- and triarylphosphine palladium catalysts for continuous-flow cross-coupling reactions: efficiency, durability, and metal leaching studies. ACS Catalysis, 5 (2), 1303-1312. doi: 10.1021/cs5020089

Benchmarking immobilized Di- and triarylphosphine palladium catalysts for continuous-flow cross-coupling reactions: efficiency, durability, and metal leaching studies

2014

Journal Article

Immobilized transition metals as catalysts for cross-couplings in continuous flow-a critical assessment of the reaction mechanism and metal leaching

Cantillo, David and Kappe, C. Oliver (2014). Immobilized transition metals as catalysts for cross-couplings in continuous flow-a critical assessment of the reaction mechanism and metal leaching. ChemCatChem, 6 (12), 3286-3305. doi: 10.1002/cctc.201402483

Immobilized transition metals as catalysts for cross-couplings in continuous flow-a critical assessment of the reaction mechanism and metal leaching

2014

Journal Article

Sequential nitration/hydrogenation protocol for the synthesis of triaminophloroglucinol: safe generation and use of an explosive intermediate under continuous-flow conditions

Cantillo, David, Damm, Markus, Dallinger, Doris, Bauser, Marcus, Berger, Markus and Kappe, C. Oliver (2014). Sequential nitration/hydrogenation protocol for the synthesis of triaminophloroglucinol: safe generation and use of an explosive intermediate under continuous-flow conditions. Organic Process Research and Development, 18 (11), 1360-1366. doi: 10.1021/op5001435

Sequential nitration/hydrogenation protocol for the synthesis of triaminophloroglucinol: safe generation and use of an explosive intermediate under continuous-flow conditions

2014

Journal Article

A continuous-flow protocol for light-induced benzylic fluorinations

Cantillo, David, de Frutos, Oscar, Rincon, Juan A., Mateos, Carlos and Kappe, C. Oliver (2014). A continuous-flow protocol for light-induced benzylic fluorinations. The Journal of Organic Chemistry, 79 (17), 8486-8490. doi: 10.1021/jo5016757

A continuous-flow protocol for light-induced benzylic fluorinations

2014

Journal Article

Stepwise formation of 1,3-diazolium-4-thiolates by munchnone cycloadditions: promising candidates for nonlinear optics

Cantillo, David, Avalos, Martin, Babiano, Reyes, Cintas, Pedro, Jimenez, Jose L., Light, Mark E., Palacios, Juan C. and Porro, Rocio (2014). Stepwise formation of 1,3-diazolium-4-thiolates by munchnone cycloadditions: promising candidates for nonlinear optics. The Journal of Organic Chemistry, 79 (9), 4201-4205. doi: 10.1021/jo500349g

Stepwise formation of 1,3-diazolium-4-thiolates by munchnone cycloadditions: promising candidates for nonlinear optics

2014

Journal Article

Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis

Cantillo, David, de Frutos, Oscar, Rincon, Juan A., Mateos, Carlos and Kappe, C. Oliver (2014). Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis. Organic Letters, 16 (3), 896-899. doi: 10.1021/ol403650y

Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis

2014

Journal Article

Effect of configuration of 2-vinyldiazocarbonyl compounds on their reactivity: experimental and computational study

Supurgibekov, Murat B., Cantillo, David, Kappe, C. Oliver, Prakash, G. K. Surya and Nikolaev, Valerij A. (2014). Effect of configuration of 2-vinyldiazocarbonyl compounds on their reactivity: experimental and computational study. Organic and Biomolecular Chemistry, 12 (4), 682-689. doi: 10.1039/c3ob42102c

Effect of configuration of 2-vinyldiazocarbonyl compounds on their reactivity: experimental and computational study

2014

Journal Article

A scalable procedure for light-induced benzylic brominations in continuous flow

Cantillo, David, de Frutos, Oscar, Rincon, Juan A., Mateos, Carlos and Kappe, C. Oliver (2014). A scalable procedure for light-induced benzylic brominations in continuous flow. The Journal of Organic Chemistry, 79 (1), 223-229. doi: 10.1021/jo402409k

A scalable procedure for light-induced benzylic brominations in continuous flow

2013

Journal Article

Direct preparation of nitriles from carboxylic acids in continuous flow

Cantillo, David and Kappe, C. Oliver (2013). Direct preparation of nitriles from carboxylic acids in continuous flow. The Journal of Organic Chemistry, 78 (20), 10567-10571. doi: 10.1021/jo401945r

Direct preparation of nitriles from carboxylic acids in continuous flow

2013

Journal Article

In situ generation of diimide from hydrazine and oxygen: continuous-flow transfer hydrogenation of olefins

Pieber, Bartholomaeus, Martinez, Sabrina Teixeira, Cantillo, David and Kappe, C. Oliver (2013). In situ generation of diimide from hydrazine and oxygen: continuous-flow transfer hydrogenation of olefins. Angewandte Chemie (International Edition), 52 (39), 10241-10244. doi: 10.1002/anie.201303528

In situ generation of diimide from hydrazine and oxygen: continuous-flow transfer hydrogenation of olefins

2013

Journal Article

Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals

Cantillo, David, Moghaddam, Mojtaba Mirhosseini and Kappe, C. Oliver (2013). Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals. Journal of Organic Chemistry, 78 (9), 4530-4542. doi: 10.1021/jo400556g

Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals

2013

Journal Article

On the Fischer indole synthesis of 7-ethyltryptophol-mechanistic and process intensification studies under continuous flow conditions

Gutmann, Bernhard, Gottsponer, Michael, Elsner, Petteri, Cantillo, David, Roberge, Dominique M. and Kappe, C. Oliver (2013). On the Fischer indole synthesis of 7-ethyltryptophol-mechanistic and process intensification studies under continuous flow conditions. Organic Process Research and Development, 17 (2), 294-302. doi: 10.1021/op300363s

On the Fischer indole synthesis of 7-ethyltryptophol-mechanistic and process intensification studies under continuous flow conditions

2012

Journal Article

An experimental and computational assessment of acid-catalyzed azide-nitrile cycloadditions

Cantillo, David, Gutmann, Bernhard and Kappe, C. Oliver (2012). An experimental and computational assessment of acid-catalyzed azide-nitrile cycloadditions. The Journal of Organic Chemistry, 77 (23), 10882-10890. doi: 10.1021/jo3022742

An experimental and computational assessment of acid-catalyzed azide-nitrile cycloadditions

2012

Journal Article

Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols

Damm, Markus, Nusshold, Christoph, Cantillo, David, Rechberger, Gerald N., Gruber, Karl, Sattler, Wolfgang and Kappe, C. Oliver (2012). Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols. Journal of Proteomics, 75 (18), 5533-5543. doi: 10.1016/j.jprot.2012.07.043

Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols

2012

Journal Article

On the prebiotic synthesis of D-sugars catalyzed by L-peptides: assessments from first-principles calculations

Cantillo, David, Avalos, Martin, Babiano, Reyes, Cintas, Pedro, Jimenez, Jose L. and Palacios, Juan C. (2012). On the prebiotic synthesis of D-sugars catalyzed by L-peptides: assessments from first-principles calculations. Chemistry: A European Journal, 18 (28), 8795-8799. doi: 10.1002/chem.201200466

On the prebiotic synthesis of D-sugars catalyzed by L-peptides: assessments from first-principles calculations