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2008 Journal Article Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycleSchenk, Gerhard, Elliott, Tristan W., Leung, Eleanor, Carrington, Lyle E., Mitic, Natasa, Gahan, Lawrence R. and Guddat, Luke W. (2008). Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Structural Biology, 8 (6) 6, 1-13. doi: 10.1186/1472-6807-8-6 |
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2008 Journal Article Structure and mechanism of inhibition of plant acetohydroxyacid synthaseDuggleby, R.G., McCourt, J.A. and Guddat, Luke W. (2008). Structure and mechanism of inhibition of plant acetohydroxyacid synthase. Plant Physiology and Biochemistry, 2008 (46), 309-324. doi: 10.1016/j.plaphy.2007.12.004 |
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2007 Journal Article Plant collagenase: Unique collagenolytic activity of cysteine proteases from gingerKim, M., Hamilton, S. E., Guddat, L. W. and Overall, C. M. (2007). Plant collagenase: Unique collagenolytic activity of cysteine proteases from ginger. Biochimica Et Biophysica Acta General Subjects, 1770 (12), 1627-1635. doi: 10.1016/j.bbagen.2007.08.003 |
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2007 Journal Article Structure, function and diversity of plant purple acid phosphatasesLeung, Eleanor W. W., Teixeira, Marina, Guddat, Luke W., Mitić, Natasa and Schenk, Gerhard (2007). Structure, function and diversity of plant purple acid phosphatases. Current Topics in Plant Biology, 8, 21-31. |
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2006 Journal Article Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferasesKeough, Dianne T., Skinner-Adams, Tina, Jones, Malcolm K., Ng, Ai-Lin., Brereton, Ian M., Guddat, Luke W. and de Jersey, John (2006). Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry, 49 (25), 7479-7486. doi: 10.1021/jm061012j |
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2006 Journal Article Structure-function relationships in human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) by random mutagenesisZheng, Yuan-Zhi, Guddat, Luke, Farlow, Anthony and de Jersey, John (2006). Structure-function relationships in human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) by random mutagenesis. Chemical Research in Chinese Universities, 22 (2), 251-252. doi: 10.1016/S1005-9040(06)60090-1 |
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2006 Journal Article The Catalytic Mechanisms of Binuclear MetallohydrolasesMitic, Natasa, Smith, Sarah J., Neves, Ademir, Guddat, Luke W., Gahan, Lawrence R. and Schenk, Gerhard (2006). The Catalytic Mechanisms of Binuclear Metallohydrolases. Chemical Reviews, 106 (8), 3338-3363. doi: 10.1021/cr050318f |
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2006 Journal Article Herbicide-binding Sites Revealed in the Structure of Plant Acetohydroxyacid SynthaseMcCourt, J. A., Pang, S. S., King-Scott, J., Guddat, L. W. and Duggleby, R. G. (2006). Herbicide-binding Sites Revealed in the Structure of Plant Acetohydroxyacid Synthase. Proceedings of The National Academy of Sciences of The United States of America, 103 (3), 569-573. doi: 10.1073/pnas.0508701103 |
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2006 Journal Article Mammalian-like purple acid phosphatases in plantsDe Jersey, J., Zheng, Yuan-Zhi, Fan, H. K., Schenk, G., Guddat, L. and Hamilton, S. (2006). Mammalian-like purple acid phosphatases in plants. Chemical Research In Chinese Universities, 22 (2), 263-264. doi: 10.1016/S1005-9040(06)60093-7 |
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2006 Journal Article Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanismElliott, T. W., Mitic, N., Gahan, L. R., Guddat, L. W. and Schenk, G. (2006). Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism. Journal of the Brazilian Chemical Society, 17 (8), 1558-1565. doi: 10.1590/S0103-50532006000800011 |
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2006 Journal Article Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilisMillers, E. K. I., Masci, P. P., Lavin, M. F., de Jersey, J. and Guddat, L. W. (2006). Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 62 (Pt 7), 642-645. doi: 10.1107/S1744309106019099 |
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2006 Journal Article Identification and molecular modeling of a novel, plant-like, human purple acid phosphataseFlanagan, J. U., Cassady, A. I., Schenk, G., Guddat, L. W. and Hume, D. A. (2006). Identification and molecular modeling of a novel, plant-like, human purple acid phosphatase. Gene, 377 (1), 12-20. doi: 10.1016/j.gene.2006.02.031 |
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2005 Journal Article The crystal structure of a bacterial Class II ketol-acid reductolsomerase: Domain conservation and evolutionTyagi, R., Duquerroy, S., Navaza, J., Guddat, L. W. and Duggleby, R. G. (2005). The crystal structure of a bacterial Class II ketol-acid reductolsomerase: Domain conservation and evolution. Protein Science, 14 (12), 3089-3100. doi: 10.1110/ps.051791305 |
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2005 Journal Article Structure-activity relationships for a new family of sulfonylurea herbicidesWang, Jian-Guo, Li, Zheng-Ming, Ma, Zheng-Ming, Wang, Bao-Lei, Jiang, Lin, Pang, Siew Siew, Lee, Yu-Ting, Guddat, Luke W. and Duggleby, Ronald G. (2005). Structure-activity relationships for a new family of sulfonylurea herbicides. Journal of Computer-aided Molecular Design, 19 (11), 801-820. doi: 10.1007/s10822-005-9028-9 |
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2005 Journal Article Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors - ReplySkinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, James S. and Andrews, Katherine T. (2005). Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors - Reply. Journal of Infectious Diseases, 191 (8), 1382-1383. doi: 10.1086/428782 |
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2005 Journal Article Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors [3] (multiple letters)Savarino, Andrea, Cauda, Roberto, Cassone, Antonio, Skinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, J. James S. and Andrews, Katherine T. (2005). Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors [3] (multiple letters). Journal of Infectious Diseases, 191 (8), 1381-1383. doi: 10.1086/428781 |
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2005 Journal Article Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthaseMcCourt, J. A., Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2005). Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. Biochemistry, 44 (7), 2330-2338. doi: 10.1021/bi047980a |
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2005 Journal Article The crystal structure of free human hypoxanthineguanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycleKeough, Dianne T., Brereton, Ian M., De Jersey, John and Guddat, Luke W. (2005). The crystal structure of free human hypoxanthineguanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle. Journal of Molecular Biology, 351 (1), 170-181. doi: 10.1016/j.jmb.2005.05.061 |
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2005 Journal Article Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphataseSchenk, G., Gahan, L. R., Carrington, L. E., Mitic, N., Valizadeh, M., Hamilton, S. E., de Jersey, J. and Guddat, L. W. (2005). Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase. Proceedings of The National Academy of Sciences of The United States of America, 102 (2), 273-278. doi: 10.1073/pnas.0407239102 |
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2005 Journal Article Probing the mechanism of the bifunctional enzyme ketol-acid reductoisomerase by site-directed mutagenesis of the active siteTyagi, Rajiv, Lee, Yu-Ting, Guddat, Luke W. and Duggleby, Ronald G. (2005). Probing the mechanism of the bifunctional enzyme ketol-acid reductoisomerase by site-directed mutagenesis of the active site. Febs Journal, 272 (2), 593-602. doi: 10.1111/j.1742-4658.2004.04506.x |
