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2001

Journal Article

Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis

Jennings, C., West, J., Waine, C., Craik, D. J. and Anderson, M. (2001). Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis. Proceedings of The National Academy of Sciences of The United States of America, 98 (19), 10614-10619. doi: 10.1073/pnas.191366898

Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis

2001

Journal Article

Chemistry, properties, and phylogenetic implications of the methylated carrageenans from red algae of the genus Areschougia (Areschougiaceae, Gigartinales, Rhodophyta)

Chiovitti, A., Kraft, G. T., Bacic, A., Craik, D. J. and Liao, M. L. (2001). Chemistry, properties, and phylogenetic implications of the methylated carrageenans from red algae of the genus Areschougia (Areschougiaceae, Gigartinales, Rhodophyta). Journal of Phycology, 37 (6), 1127-1137. doi: 10.1046/j.1529-8817.2001.01086.x

Chemistry, properties, and phylogenetic implications of the methylated carrageenans from red algae of the genus Areschougia (Areschougiaceae, Gigartinales, Rhodophyta)

2001

Journal Article

The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata

Schirra, H. J., Scanlon, M. J., Lee, M. C. S., Anderson, M. A. and Craik, D. J. (2001). The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata. Journal of Molecular Biology, 306 (1), 69-79. doi: 10.1006/jmbi.2000.4318

The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata

2001

Journal Article

The cystine knot motif in toxins and implications for drug design

Craik, D. J., Daly, N. L. and Waine, C. (2001). The cystine knot motif in toxins and implications for drug design. Toxicon, 39 (1), 43-60. doi: 10.1016/S0041-0101(00)00160-4

The cystine knot motif in toxins and implications for drug design

2001

Journal Article

Alpha-conotoxins: Nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leads

Dutton, J. L. and Craik, D. J. (2001). Alpha-conotoxins: Nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leads. Current Medicinal Chemistry, 8 (4), 327-344. doi: 10.2174/0929867013373453

Alpha-conotoxins: Nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leads

2001

Journal Article

Ring flexibility within tricyclic antidepressant drugs

Casarotto, M. G. and Craik, D. J. (2001). Ring flexibility within tricyclic antidepressant drugs. Journal of Pharmaceutical Sciences, 90 (6), 713-721. doi: 10.1002/jps.1027

Ring flexibility within tricyclic antidepressant drugs

2001

Journal Article

Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from rhesus macaque leukocytes

Trabi, M., Schirra, H. J. and Craik, D. J. (2001). Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from rhesus macaque leukocytes. Biochemistry, 40 (14), 4211-4221. doi: 10.1021/bi002028t

Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from rhesus macaque leukocytes

2001

Journal Article

Solution structures by H-1 NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant

Korsinczky, M. L. J., Schirra, H. J., Rosengren, K. J., West, J., Condie, B. A., Otvos, L., Anderson, M. A. and Craik, D. J. (2001). Solution structures by H-1 NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant. Journal of Molecular Biology, 311 (3), 579-591. doi: 10.1006/jmbi.2001.4887

Solution structures by H-1 NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant

2000

Journal Article

Pharmaceutical applications of NMR

Craik, David J. and Scanlon, Martin J. (2000). Pharmaceutical applications of NMR. Annual Reports on NMR Spectroscopy, 42, 115-174.

Pharmaceutical applications of NMR

2000

Journal Article

Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F)

Poulsen, Sally-Ann, Watson, Andrew A., Fairlie, David P. and Craik, David J. (2000). Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F). Journal of Structural Biology, 130 (2-3), 142-152. doi: 10.1006/jsbi.2000.4267

Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F)

2000

Journal Article

Insect peptides with improved protease-resistance protect mice against bacterial infection

Otvos, L. J., Bokonyi, K., Varga, I., Otvos, B. I., Hoffmann, R., Ertl, H. C. J., Wade, J. D., McManus, AM, Craik, D. J. and Bulet, P. (2000). Insect peptides with improved protease-resistance protect mice against bacterial infection. Protein Science, 9 (4), 742-749. doi: 10.1110/ps.9.4.742

Insect peptides with improved protease-resistance protect mice against bacterial infection

2000

Journal Article

Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site

Abbenante, G., Kovacs, D. M., Leung, D. L., Craik, D. J., Tanzi, R. E. and Fairlie, D. P. (2000). Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site. Biochemical And Biophysical Research Communications, 268 (1), 133-135. doi: 10.1006/bbrc.2000.2098

Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site

2000

Journal Article

Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 2. Three-dimensional solution structure

Hill, JM, Alewood, PF and Craik, DJ (2000). Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 2. Three-dimensional solution structure. European Journal of Biochemistry, 267 (15), 4649-4657. doi: 10.1046/j.1432-1327.2000.01507.x

Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 2. Three-dimensional solution structure

2000

Journal Article

Acyclic permutants of naturally occurring cyclic proteins - Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1

Daly, NL and Craik, DJ (2000). Acyclic permutants of naturally occurring cyclic proteins - Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1. Journal of Biological Chemistry, 275 (25), 19068-19075. doi: 10.1074/jbc.M000450200

Acyclic permutants of naturally occurring cyclic proteins - Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1

2000

Journal Article

Chemical synthesis, characterization and activity of RK-1, a novel alpha-defensin-related peptide

Dawson, Nicola F., Craik, David J., McManus, Ailsa M., Dashper, Stuart G., Reynolds, Eric C., Tregear, Geoffrey W., Otvos, Laszlo and Wade, John D. (2000). Chemical synthesis, characterization and activity of RK-1, a novel alpha-defensin-related peptide. Journal of Peptide Science, 6 (1), 19-25. doi: 10.1002/(SICI)1099-1387(200001)6:13.3.CO;2-T

Chemical synthesis, characterization and activity of RK-1, a novel alpha-defensin-related peptide

2000

Journal Article

Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease

Daly, N. L., Hoffmann, R., Otvos, L. J. and Craik, D. J. (2000). Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease. Biochemistry, 39 (30), 9039-9046. doi: 10.1021/bi0004807

Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease

2000

Journal Article

Three-dimensional structure of RK-1: A novel alpha-defensin peptide

McManus, A. M., Dawson, N. F., Wade, J. D., Carrington, L. E., Winzor, D. J. and Craik, D. J. (2000). Three-dimensional structure of RK-1: A novel alpha-defensin peptide. Biochemistry, 39 (51), 15757-15764. doi: 10.1021/bi000457l

Three-dimensional structure of RK-1: A novel alpha-defensin peptide

2000

Journal Article

Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 1. Isolation, characterization and chemical synthesis

Hill, J. M., Atkins, A. R., Loughnan, M. L., Jones, A., Adams, D. A., Martin, R. C., Lewis, R. J., Craik, D. J. and Alewood, P. F. (2000). Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 1. Isolation, characterization and chemical synthesis. European Journal of Biochemistry, 267 (15), 4642-4648. doi: 10.1046/j.1432-1327.2000.01508.x

Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 1. Isolation, characterization and chemical synthesis

2000

Journal Article

Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes

Lewis, Richard J., Nielsen, Katherine J., Craik, David J., Loughnan, Marion L., Adams, Denise A., Sharpe, Iain A., Luchian, Tudor, Adams, David J., Bond, Trudy, Thomas, Linda, Jones, Alun, Matheson, Jodi-Lea, Drinkwater, Roger, Andrews, Peter R. and Alewood, Paul F. (2000). Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. Journal of Biological Chemistry, 275 (45), 35335-35344. doi: 10.1074/jbc.M002252200

Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes

2000

Journal Article

Acyclic permutants of naturally occurring cyclic proteins

Daly, N. L. and Craik, D. J. (2000). Acyclic permutants of naturally occurring cyclic proteins. The Journal of Biological Chemistry, 275 (25), 19068-19075.

Acyclic permutants of naturally occurring cyclic proteins