2015 Journal Article Cytokines in graft-versus-host diseaseHenden, Andrea S. and Hill, Geoffrey R. (2015). Cytokines in graft-versus-host disease. Journal of Immunology, 194 (10), 4604-4612. doi: 10.4049/jimmunol.1500117 |
2015 Journal Article Autophagy is required for stem cell mobilization by G-CSFLeveque-El Mouttie, Lucie, Vu, Therese, Lineburg, Katie E., Kuns, Rachel D., Bagger, Frederik O., Teal, Bianca E., Lor, Mary, Boyle, Glen M., Bruedigam, Claudia, Mintern, Justine D., Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2015). Autophagy is required for stem cell mobilization by G-CSF. Blood, 125 (19), 2933-2936. doi: 10.1182/blood-2014-03-562660 |
2015 Journal Article NK cells require IL-28R for optimal in vivo activitySouza-Fonseca-Guimaraes, Fernando, Young, Arabella, Mittal, Deepak, Martinet, Ludovic, Bruedigam, Claudia, Takeda, Kazuyoshi, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Hill, Geoffrey R. and Smyth, Mark J. (2015). NK cells require IL-28R for optimal in vivo activity. Proceedings of the National Academy of Sciences of the United States of America, 112 (18), E2376-E2384. doi: 10.1073/pnas.1424241112 |
2015 Journal Article Immunosurveillance and therapy of multiple myeloma are CD226 dependentGuillerey, Camille, de Andrade, Lucas Ferrari, Vuckovic, Slavica, Miles, Kim, Ngiow, Shin Foong, Yong, Michelle C. R., Teng, Michele W. L., Colonna, Marco, Ritchie, David S., Chesi, Martha, Bergsagel, P. Leif, Hill, Geoffrey R., Smyth, Mark J. and Martinet, Ludovic (2015). Immunosurveillance and therapy of multiple myeloma are CD226 dependent. Journal of Clinical Investigation, 125 (5), 2077-2089. doi: 10.1172/JCI77181 |
Featured 2015 Journal Article Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantationVarelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen A., Yanik, Gregory A., Blazar, Bruce R., Tey, Siok-Keen, Clouston, Andrew D., MacDonald, Kelli P. A., Cooke, Kenneth R. and Hill, Geoffrey R. (2015). Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. Blood, 125 (15), 2435-2444. doi: 10.1182/blood-2014-07-590232 |
2015 Journal Article CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cellsPaget, C., Chow, M. T., Gherardin, N. A., Beavis, P. A., Uldrich, A. P., Duret, H., Hassane, M., Souza-Fonseca-Guimaraes, F., Mogilenko, D. A., Staumont-Salle, D., Escalante, N. K., Hill, G. R., Neeson, P., Ritchie, D. S., Dombrowicz, D., Mallevaey, T., Trottein, F., Belz, G. T., Godfrey, D. I. and Smyth, M. J. (2015). CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells. Immunology and Cell Biology, 93 (2), 198-212. doi: 10.1038/icb.2014.94 |
2015 Journal Article Autophagy and haematopoietic stem cell transplantationLeveque, Lucie, Le Texier, Laetitia, Lineburg, Katie E., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2015). Autophagy and haematopoietic stem cell transplantation. Immunology and Cell Biology, 93 (1), 43-50. doi: 10.1038/icb.2014.95 |
2015 Journal Article Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivationTey, S.-K., Davenport, M. P., Hill, G. R., Kennedy, G. A., Durrant, S. T., Khanna, R. and Cromer, D. (2015). Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivation. Bone Marrow Transplantation, 50 (2), 315-316. doi: 10.1038/bmt.2014.265 |
2015 Journal Article α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in miceUryu, Hidetaka, Hashimoto, Daigo, Kato, Koji, Hayase, Eiko, Matsuoka, Satomi, Ogasawara, Reiki, Takahashi, Shuichiro, Maeda, Yoshinobu, Iwasaki, Hiromi, Miyamoto, Toshihiro, Saijo, Shinobu, Iwakura, Yoichiro, Hill, Geoffrey R., Akashi, Koichi and Teshima, Takanori (2015). α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice. Blood, 125 (19), 3014-3023. doi: 10.1182/blood-2014-12-615781 |
2015 Journal Article Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammationUllah, Md Ashik, Revez, Joana A., Loh, Zhixuan, Simpson, Jennifer, Zhang, Vivian, Bain, Lisa, Varelias, Antiopi, Rose-John, Stefan, Blumenthal, Antje, Smyth, Mark J., Hill, Geoffrey R., Sukkar, Manuel A. R, Ferreira M. A. R. and Phipps, Simon (2015). Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation. Journal of Allergy and Clinical Immunology, 136 (4), 1065-1073. doi: 10.1016/j.jaci.2015.02.032 |
2014 Journal Article Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapyBruedigam, C., Bagger, F.O., Heidel, F.H., Paine, Kuhn C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W. (2014). Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. Cell Stem Cell, 15 (6), 775-790. doi: 10.1016/j.stem.2014.11.010 |
Featured 2014 Journal Article Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trialKennedy, Glen A., Varelias, Antiopi, Vuckovic, Slavica, Le Texier, Laetitia, Gartlan, Kate H., Zhang, Ping, Thomas, Gethin, Anderson, Lisa, Boyle, Glen, Cloonan, Nicole, Leach, Justine, Sturgeon, Elise, Avery, Judy, Olver, Stuart D., Lor, Mary, Misra, Ashish K., Hutchins, Cheryl, Morton, A. James, Durrant, Simon T. S., Subramoniapillai, Elango, Butler, Jason P., Curley, Cameron I., MacDonald, Kelli P. A., Tey, Siok-Keen and Hill, Geoffrey R. (2014). Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial. The Lancet Oncology, 15 (13), 1451-1459. doi: 10.1016/S1470-2045(14)71017-4 |
2014 Journal Article Ibrutinib treatment ameliorates murine chronic graft-versus-host diseaseDubovsky, Jason A., Flynn, Ryan, Du, Jing, Harrington, Bonnie K., Zhong, Yiming, Kaffenberger, Benjamin, Yang, Carrie, Towns, William H., Lehman, Amy, Johnson, Amy J., Muthusamy, Natarajan, Devine, Steven M., Jaglowski, Samantha, Serody, Jonathan S., Murphy, William J., Munn, David H., Luznik, Leo, Hill, Geoffrey R., Wong, Henry K., MacDonald, Kelli K. P., Maillard, Ivan, Koreth, John, Elias, Laurence, Cutler, Corey, Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Panoskaltsis-Mortari, Angela, Byrd, John C. and Blazar, Bruce R. (2014). Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. Journal of Clinical Investigation, 124 (11), 4867-4876. doi: 10.1172/JCI75328 |
2014 Journal Article TRAIL+ NK Cells Control CD4+ T Cell Responses during Chronic Viral Infection to Limit AutoimmunitySchuster, Iona S., Wikstrom, Matthew E., Brizard, Geraldine, Coudert, Jerome D., Estcourt, Marie J., Manzur, Mitali, O'Reilly, Lorraine A., Smyth, Mark J., Trapani, Joseph A., Hill, Geoffrey R., Andoniou, Christopher E. and Degli-Esposti, Mariapia A. (2014). TRAIL+ NK Cells Control CD4+ T Cell Responses during Chronic Viral Infection to Limit Autoimmunity. Immunity, 41 (4), 646-656. doi: 10.1016/j.immuni.2014.09.013 |
2014 Journal Article Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosisSmith, Daniel J., Hill, Geoffrey R., Bell, Scott C. and Reid, David W. (2014). Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis. PLoS ONE, 9 (10) e109891, 1-8. doi: 10.1371/journal.pone.0109891 |
2014 Journal Article CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host diseaseAlexander K.A., Flynn R., Lineburg K.E., Kuns R.D., Teal B.E., Olver S.D., Lor M., Raffelt N.C., Koyama M., Leveque L., Le Texier L., Melino M., Markey K.A., Varelias A., Engwerda C., Serody J.S., Janela B., Ginhoux F., Clouston A.D., Blazar B.R., Hill G.R. and MacDonald K.P.A. (2014). CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease. Journal of Clinical Investigation, 124 (10), 4266-4280. doi: 10.1172/JCI75935 |
2014 Journal Article The biology of graft-versus-host disease: experimental systems instructing clinical practiceMarkey, Kate A., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2014). The biology of graft-versus-host disease: experimental systems instructing clinical practice. Blood, 124 (3), 354-362. doi: 10.1182/blood-2014-02-514745 |
2014 Journal Article Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliteransFlynn, Ryan, Du, Jing, Veenstra, Rachelle G., Reichenbach, Dawn K., Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Freeman, Gordon J., Serody, Jonathan S., Murphy, William J., Munn, David H., Sarantopoulos, Stefanie, Luznik, Leo, Maillard, Ivan, Koreth, John, Cutler, Corey, Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Dubovsky, Jason A., Byrd, John C., MacDonald, Kelli P., Hill, Geoff R. and Blazar, Bruce R. (2014). Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood, 123 (25), 3988-3998. doi: 10.1182/blood-2014-03-562231 |
2014 Journal Article Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunityHaque, Ashraful, Best, Shannon E., De Oca, Marcela Montes, James, Kylie R., Ammerdorffer, Anne, Edwards, Chelsea L., De Labastida Rivera, Fabian, Amante, Fiona H., Bunn, Patrick T., Sheel, Meru, Sebina, Ismail, Koyama, Motoko, Varelias, Antiopi, Hertzog, Paul J., Kalinke, Ulrich, Gun, Sin Yee, Renia, Laurent, Ruedl, Christiane, MacDonald, Kelli P.A., Hill, Geoffrey R. and Engwerda, Christian R. (2014). Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity. Journal of Clinical Investigation, 124 (6), 2483-2496. doi: 10.1172/JCI70698 |
2014 Journal Article Cross-dressing by donor dendritic cells after allogeneic bone marrow transplantation contributes to formation of the immunological synapse and maximizes responses to indirectly presented antigenMarkey, Kate A., Koyama, Motoko, Gartlan, Kate H., Leveque, Lucie, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2014). Cross-dressing by donor dendritic cells after allogeneic bone marrow transplantation contributes to formation of the immunological synapse and maximizes responses to indirectly presented antigen. Journal of Immunology, 192 (11), 5426-5433. doi: 10.4049/jimmunol.1302490 |