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2014 Journal Article Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10MacDonald, Kelli P. A., Le Texier, Laetitia, Zhang, Ping, Morris, Helen, Kuns, Rachel D., Lineburg, Katie E., Leveque, Lucie, Don, Alistair L., Markey, Kate A., Vuckovic, Slavica, Bagger, Frederik O., Boyle, Glen M., Blazar, Bruce R. and Hill, Geoffrey R. (2014). Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10. Journal of Immunology, 192 (7), 3180-3189. doi: 10.4049/jimmunol.1302315 |
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2014 Journal Article Immunotherapy following relapse of acute leukaemia after T-cell-replete allogeneic peripheral blood progenitor cell transplantation: importance of new onset chronic graft-versus-host diseaseCurley, C., Hill, G. R., McLean, A. and Kennedy, G. A. (2014). Immunotherapy following relapse of acute leukaemia after T-cell-replete allogeneic peripheral blood progenitor cell transplantation: importance of new onset chronic graft-versus-host disease. International Journal of Laboratory Hematology, 36 (2), 197-204. doi: 10.1111/ijlh.12153 |
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2014 Journal Article Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioningKoyama, M., Hashimoto, D., Nagafuji, K., Eto, T., Ohno, Y., Aoyama, K., Iwasaki, H., Miyamoto, T., Hill, G.R., Akashi, K. and Teshima, T. (2014). Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning. Bone Marrow Transplantation, 49 (1), 110-115. doi: 10.1038/bmt.2013.134 |
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2014 Journal Article The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signalsWikstrom, Matthew E., Khong, Andrea, Fleming, Peter, Kuns, Rachel, Hertzog, Paul J., Frazer, Ian H., Andoniou, Christopher E., Hill, Geoffrey R. and Degli-Esposti, Mariapia A. (2014). The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals. European Journal of Immunology, 44 (2), 409-419. doi: 10.1002/eji.201243109 |
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2013 Journal Article PD-1 dependent exhaustion of CD8+ T cells drives chronic malariaHorne-Debets, Joshua M., Faleiro, Rebecca, Karunarathne, Deshapriya S., Liu, Xue Q., Lineburg, Katie E., Poh, Chek Meng, Grotenbreg, Gijsbert M., Hill, Geoffrey R., MacDonald, Kelli P. A., Good, Michael F., Renia, Laurent, Ahmed, Rafi, Sharpe, Arlene H. and Wykes, Michelle N. (2013). PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria. Cell Reports, 5 (5), 1204-1213. doi: 10.1016/j.celrep.2013.11.002 |
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2013 Journal Article Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem cell transplantationAndani, Rafiq, Robertson, Ivan, MacDonald, Kelli P. A., Durrant, Simon, Hill, Geoffrey R. and Khosrotehrani, Kiarash (2013). Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem cell transplantation. Experimental Dermatology, Accepted Article (1), 1-11. doi: 10.1111/exd.12301 |
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2013 Journal Article Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivoZhang, Ping, Tey, Siok-Keen, Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Raju, Jyothy, Leveque, Lucie, Markey, Kate A., Varelias, Antiopi, Clouston, Andrew D., Lane, Steven W., Macdonald, Kelli P. A. and Hill, Geoffrey R. (2013). Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. Journal of Immunology, 191 (10), 5291-5303. doi: 10.4049/jimmunol.1301181 |
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2013 Journal Article Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection ComplicationsTey, Siok-Keen, Kennedy, Glen A., Cromer, Deborah, Davenport, Miles P., Walker, Susan, Jones, Linda I., Crough, Tania, Durrant, Simon T., Morton, James A., Butler, Jason P., Misra, Ashish K., Hill, Geoffrey R. and Khanna, Rajiv (2013). Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection Complications. PLoS ONE, 8 (10) e74744, e74744. doi: 10.1371/journal.pone.0074744 |
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2013 Journal Article CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus.Ong, Monique L., Wikstrom, Matthew E., Fleming, Peter, Estcourt, Marie J., Hertzog, Paul J., Hill, Geoffrey R., Andoniou, Christopher E. and Degli-Esposti, Mariapia A. (2013). CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus.. Blood, 122 (1), 55-60. doi: 10.1182/blood-2012-12-471227 |
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2013 Journal Article UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophagesHandoko, Herlina Y., Rodero, Mathieu P., Boyle, Glen M., Ferguson, Blake, Engwerda, Christian, Hill, Geoff, Muller, H. Konrad, Khosrotehrani, Kiarash and Walker, Graeme J. (2013). UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages. Journal of Investigative Dermatology, 133 (7), 1803-1812. doi: 10.1038/jid.2013.9 |
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2013 Journal Article Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia veraMullally, Ann, Bruedigam, Claudia, Poveromo, Luke, Heidel, Florian H., Purdon, Amy, Vu, Therese, Austin, Rebecca, Heckl, Dirk, Breyfogle, Lawrence J., Kuhn, Catherine Paine, Kalaitzidis, Demetrios, Armstrong, Scott A., Williams, David A., Hill, Geoff R., Ebert, Benjamin L. and Lane, Steven W. (2013). Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera. Blood, 121 (18), 3692-3702. doi: 10.1182/blood-2012-05-432989 |
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2013 Journal Article Promoting regulation via the inhibition of DNAM-1 after transplantationKoyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Leveque, Lucie, Chan, Christopher J., Robb, Renee J., Markey, Kate A., Alexander, Kylie A., Varelias, Antiopi, Clouston, Andrew D., Smyth, Mark J., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2013). Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood, 121 (17), 3511-3520. doi: 10.1182/blood-2012-07-444026 |
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2013 Journal Article CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3Seillet, Cyril, Jackson, Jacob T., Markey, Kate A., Brady, Hugh J. M., Hill, Geoffrey R., MacDonald, Kelli P. A., Nutt, Stephen L. and Belz, Gabrielle T. (2013). CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3. Blood, 121 (9), 1574-1583. doi: 10.1182/blood-2012-07-445650 |
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2013 Journal Article Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacyColeman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100 |
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2013 Journal Article Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infectionZinkernagel, M.S., Chinnery, H.R., Ong, M.L., Petitjean, C., Voigt, V., McLenachan, S., McMenamin, P.G., Hill, G.R., Forrester, J.V., Wikstrom, M.E. and Degli-Esposti, M.A. (2013). Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection. American Journal of Pathology, 182 (3), 875-885. doi: 10.1016/j.ajpath.2012.11.031 |
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2012 Journal Article Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantationRobb, R.J., Lineburg, K.E., Kuns, R.D., Wilson, Y.A., Raffelt, N.C., Olver, S.D., Varelias, A., Alexander, K.A., Teal, B.E., Sparwasser, T., Hammerling, G.J., Markey, K.A., Koyama, M., Clouston, A.D., Engwerda, C.R., Hill, G.R. and MacDonald, K.P.A. (2012). Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation. Blood, 119 (24), 5898-5908. doi: 10.1182/blood-2011-12-396119 |
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2012 Journal Article Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsetsMarkey, Kate A., Koyama, Motoko, Kuns, Rachel D., Lineburg, Katie E., Wilson, Yana A., Olver, Stuart D., Raffelt, Neil C., Don, Alistair L. J., Varelias, Antiopi, Robb, Renee J., Cheong, Melody, Engwerda, Christian R., Steptoe, Raymond J., Ramshaw, Hayley S., Lopez, Angel F., Vega-Ramos, Javier, Lew, Andrew M., Villadangos, Jose A., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2012). Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood, 119 (24), 5918-5930. doi: 10.1182/blood-2011-12-398164 |
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2012 Journal Article The interferon-dependent orchestration of innate and adaptive immunity after transplantationRobb, R.J. and Hill, G.R. (2012). The interferon-dependent orchestration of innate and adaptive immunity after transplantation. Blood, 119 (23), 5351-5358. doi: 10.1182/blood-2012-02-368076 |
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2012 Journal Article The IL-17 Differentiation Pathway and Its Role in Transplant OutcomeSerody, J.S. and Hill, G.R. (2012). The IL-17 Differentiation Pathway and Its Role in Transplant Outcome. Biology of Blood and Marrow Transplantation, 18 (1 SUPPL.), S56-S61. doi: 10.1016/j.bbmt.2011.10.001 |
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2012 Journal Article Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host diseaseKoyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Raffelt, Neil C., Wilson, Yana A., Don, Alistair L. J., Lineburg, Katie E., Cheong, Melody, Robb, Renee J., Markey, Kate A., Varelias, Antiopi, Malissen, Bernard, Hammerling, Gunter J., Clouston, Andrew D., Engwerda, Christian R., Bhat, Purnima, MacDonald, Kelli P. A. and Hill, Geoffrey R. (2012). Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease. Nature Medicine, 18 (1), 135-142. doi: 10.1038/nm.2597 |
