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2023

Journal Article

Impact of GVHD prophylaxis on CMV reactivation and disease after HLA-matched peripheral blood stem cell transplantation

Ueda Oshima, Masumi, Xie, Hu, Zamora, Danniel, Flowers, Mary E., Hill, Geoffrey R, Mielcarek, Marco, Sandmaier, Brenda M, Gooley, Theodore A and Boeckh, Michael J. (2023). Impact of GVHD prophylaxis on CMV reactivation and disease after HLA-matched peripheral blood stem cell transplantation. Blood Advances, 7 (8), 1394-1403. doi: 10.1182/bloodadvances.2022009112

Impact of GVHD prophylaxis on CMV reactivation and disease after HLA-matched peripheral blood stem cell transplantation

2023

Journal Article

Oncogenic drivers dictate immune control of acute myeloid leukemia

Austin, Rebecca J., Straube, Jasmin, Halder, Rohit, Janardhanan, Yashaswini, Bruedigam, Claudia, Witkowski, Matthew, Cooper, Leanne, Porter, Amy, Braun, Matthias, Souza-Fonseca-Guimaraes, Fernando, Minnie, Simone A., Cooper, Emily, Jacquelin, Sebastien, Song, Axia, Bald, Tobias, Nakamura, Kyohei, Hill, Geoffrey R., Aifantis, Iannis, Lane, Steven W. and Bywater, Megan J. (2023). Oncogenic drivers dictate immune control of acute myeloid leukemia. Nature Communications, 14 (1) 2155, 1-14. doi: 10.1038/s41467-023-37592-9

Oncogenic drivers dictate immune control of acute myeloid leukemia

2023

Journal Article

Infection induces tissue-resident memory NK cells that safeguard tissue health

Schuster, Iona S., Sng, Xavier Y. X., Lau, Colleen M., Powell, David R., Weizman, Orr-El, Fleming, Peter, Neate, Georgia E. G., Voigt, Valentina, Sheppard, Sam, Maraskovsky, Andreas I., Daly, Sheridan, Koyama, Motoko, Hill, Geoffrey R., Turner, Stephen J., O’Sullivan, Timothy E., Sun, Joseph C., Andoniou, Christopher E. and Degli-Esposti, Mariapia A. (2023). Infection induces tissue-resident memory NK cells that safeguard tissue health. Immunity, 56 (3), 531-546.e6. doi: 10.1016/j.immuni.2023.01.016

Infection induces tissue-resident memory NK cells that safeguard tissue health

2023

Journal Article

A novel RIPK1 inhibitor attenuates GVHD

Hill, Geoffrey R. and Koyama, Motoko (2023). A novel RIPK1 inhibitor attenuates GVHD. Blood, 141 (9), 969-970. doi: 10.1182/blood.2022019019

A novel RIPK1 inhibitor attenuates GVHD

2023

Journal Article

Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity

Larson, Jemma H., Jin, Sujeong, Loschi, Michael, Wagers, Sara Bolivar, Thangavelu, Govindarajan, Zaiken, Michael C., McDonald-Hyman, Cameron, Saha, Asim, Aguilar, Ethan G., Koehn, Brent, Osborn, Mark J., Panoskaltsis-Mortari, Angela, Macdonald, Kelli P.A., Hill, Geoffrey R., Murphy, William J., Serody, Jonathan S, Maillard, Ivan, Kean, Leslie S., Kim, Sangwon V., Littman, Dan R. and Blazar, Bruce R. (2023). Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. American Journal of Transplantation, 23 (8), 1102-1115. doi: 10.1016/j.ajt.2023.01.030

Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity

2023

Journal Article

Corrigendum: IL-10–producing Th1 cells possess a distinct molecular signature in malaria

Edwards, Chelsea L., Ng, Susanna S., de Labastida Rivera, Fabian, Corvino, Dillon, Engel, Jessica A., Montes de Oca, Marcela, Bukali, Luzia, Frame, Teija C.M., Bunn, Patrick T., Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Wang, Yulin, Na, Jinrui, Amante, Fiona H., Loughland, Jessica R., Soon, Megan S.F., Waddell, Nicola, Mukhopadhay, Pamela, Koufariotis, Lambros T., Johnston, Rebecca L., Lee, Jason S., Kuns, Rachel, Zhang, Ping, Boyle, Michelle J., Hill, Geoffrey R., McCarthy, James S., Kumar, Rajiv and Engwerda, Christian R. (2023). Corrigendum: IL-10–producing Th1 cells possess a distinct molecular signature in malaria. Journal of Clinical Investigation, 133 (4) e169299. doi: 10.1172/jci169299

Corrigendum: IL-10–producing Th1 cells possess a distinct molecular signature in malaria

2023

Conference Publication

Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation

Geramita, Emily, Ventura, Kedwin, Bhise, Shruti, Moore, Erika, Krakow, Elizabeth F., Hill, Geoffrey R., Furlan, Scott N., Shlomchik, Warren D. and Ito, Sawa (2023). Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation. 2023 Tandem Meetings of ASTCT and CIBMTR, Orlando, FL United States, 15-19 February 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s2666-6367(23)00122-7

Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation

2023

Conference Publication

Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease

Boiko, Julie R., Ensbey, Kathleen S., Schmidt, Christine R., Waltner, Olivia G., Minnie, Simone A., Furlan, Scott N. and Hill, Geoffrey R. (2023). Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease. 2023 Tandem Meetings of ASTCT and CIBMTR, Orlando, FL United States, 15-19 February 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s2666-6367(23)00389-5

Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease

2023

Journal Article

IL-10-producing Th1 cells possess a distinct molecular signature in malaria

Edwards, Chelsea L., Ng, Susanna S., de Labastida Rivera, Fabian, Corvino, Dillon, Engel, Jessica A., Montes de Oca, Marcela, Bukali, Luzia, Frame, Teija C.M., Bunn, Patrick T., Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Wang, Yulin, Na, Jinrui, Amante, Fiona H., Loughland, Jessica R., Soon, Megan S.F., Waddell, Nicola, Mukhopadhay, Pamela, Koufariotis, Lambros T., Johnston, Rebecca L., Lee, Jason S., Kuns, Rachel, Zhang, Ping, Boyle, Michelle J., Hill, Geoffrey R., McCarthy, James S., Kumar, Rajiv and Engwerda, Christian R. (2023). IL-10-producing Th1 cells possess a distinct molecular signature in malaria. Journal of Clinical Investigation, 133 (1) e153733, 1-15. doi: 10.1172/jci153733

IL-10-producing Th1 cells possess a distinct molecular signature in malaria

2023

Journal Article

Supporting family members requested to donate hematopoietic stem cells to a relative: development and pilot testing of a psycho-educational resource

Zomerdijk, Nienke, Turner, Jane, Gottlieb, David, Barnes, Annette, Butler, Jason P., Markey, Kate A. and Hill, Geoffrey R. (2023). Supporting family members requested to donate hematopoietic stem cells to a relative: development and pilot testing of a psycho-educational resource. Journal of Psychosocial Oncology Research & Practice, 5 (1), 1-7. doi: 10.1097/or9.0000000000000095

Supporting family members requested to donate hematopoietic stem cells to a relative: development and pilot testing of a psycho-educational resource

2023

Journal Article

Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche

Koyama, Motoko, Samson, Luke, Ensbey, Kathleen S., Takahashi, Shuichiro, Clouston, Andrew D., Martin, Paul J. and Hill, Geoffrey R. (2023). Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche. Blood, 141 (3), 315-319. doi: 10.1182/blood.2022015808

Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche

2022

Journal Article

TIGIT inhibition and lenalidomide synergistically promote anti-myeloma immune responses after stem cell transplantation in mice

Minnie, Simone A., Waltner, Olivia G., Ensbey, Kathleen S., Olver, Stuart D., Collinge, Alika D., Sester, David P., Schmidt, Christine R., Legg, Samuel R.W., Takahashi, Shuichiro, Nemychenkov, Nicole S., Sekiguchi, Tomoko, Driessens, Gregory, Zhang, Ping, Koyama, Motoko, Spencer, Andrew, Holmberg, Leona A., Furlan, Scott N., Varelias, Antiopi and Hill, Geoffrey R. (2022). TIGIT inhibition and lenalidomide synergistically promote anti-myeloma immune responses after stem cell transplantation in mice. Journal of Clinical Investigation, 133 (4) e157907, 1-11. doi: 10.1172/jci157907

TIGIT inhibition and lenalidomide synergistically promote anti-myeloma immune responses after stem cell transplantation in mice

2022

Conference Publication

A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients

Hill, Joshua A., Lee, Yeon Joo, Vande Vusse, Lisa K., Xie, Hu, Lisa Chung, E., Keane-Candib, Jacob, Waghmare, Alpana, Cheng, Guang-Shing, Zhu, Haiying, Huang, Meei-Li, Hill, Geoffrey, Jerome, Keith R., Gharib, Sina A, Leisenring, Wendy M., Zerr, Danielle M., Dadwal, Sanjeet S. and Boeckh, Michael J. (2022). A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients. IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.1716

A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients

2022

Conference Publication

Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT)

Zamora, Danniel, Krantz, Elizabeth M., Joncas-Schronce, Laurel, Akoto, Brenda, Stevens-Ayers, Terry L., Bender Ignacio, Rachel A., Hill, Joshua A., Degli-Esposti, Mariapia, Hill, Geoffrey and Boeckh, Michael J. (2022). Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT). IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.549

Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT)

2022

Conference Publication

CMV Reactivation in Hematopoietic Cell Transplant Candidates: A Novel Risk Factor for Post-transplant Reactivation

Zamora, Danniel, Xie, Hu, Hill, Joshua A., Duke, Elizabeth, Green, Margaret, Kimball, Louise E., Holmberg, Leona, Waghmare, Alpana, Greninger, Alexander L., Jerome, Keith R., Flowers, Mary, Hill, Geoffrey, Leisenring, Wendy M. and Boeckh, Michael J. (2022). CMV Reactivation in Hematopoietic Cell Transplant Candidates: A Novel Risk Factor for Post-transplant Reactivation. IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.683

CMV Reactivation in Hematopoietic Cell Transplant Candidates: A Novel Risk Factor for Post-transplant Reactivation

2022

Conference Publication

Lithium Attenuates Graft-Versus-Host Disease Via Effects on the Intestinal Stem Cell Niche

Koyama, Motoko, Samson, Luke, Ensbey, Kathleen S., Clouston, Andrew D., Martin, Paul J. and Hill, Geoffrey R. (2022). Lithium Attenuates Graft-Versus-Host Disease Via Effects on the Intestinal Stem Cell Niche. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-162592

Lithium Attenuates Graft-Versus-Host Disease Via Effects on the Intestinal Stem Cell Niche

2022

Journal Article

Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity

Minnie, Simone A., Waltner, Olivia G., Ensbey, Kathleen S., Nemychenkov, Nicole S., Schmidt, Christine R., Bhise, Shruti S., Legg, Samuel R. W., Campoy, Gabriela, Samson, Luke D., Kuns, Rachel D., Zhou, Ting, Huck, John D., Vuckovic, Slavica, Zamora, Danniel, Yeh, Albert, Spencer, Andrew, Koyama, Motoko, Markey, Kate A., Lane, Steven W., Boeckh, Michael, Ring, Aaron M., Furlan, Scott N. and Hill, Geoffrey R. (2022). Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity. Science Immunology, 7 (76) eabo3420, 1-18. doi: 10.1126/sciimmunol.abo3420

Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity

2022

Journal Article

Multiplex microsphere PCR (mmPCR) allows simultaneous gram typing, detection of fungal DNA, and antibiotic resistance genes

Browne, Daniel J., Liang, Fang, Gartlan, Kate H., Harris, Patrick N. A., Hill, Geoffrey R., Corrie, Simon R. and Markey, Kate A. (2022). Multiplex microsphere PCR (mmPCR) allows simultaneous gram typing, detection of fungal DNA, and antibiotic resistance genes. Laboratory Medicine, 53 (5), 459-464. doi: 10.1093/labmed/lmac023

Multiplex microsphere PCR (mmPCR) allows simultaneous gram typing, detection of fungal DNA, and antibiotic resistance genes

2022

Conference Publication

CD8 T cells display distinct trajectories of T cell exhaustion in the bone marrow of mice with multiple myeloma

Minnie, Simone A., Nemychenkov, Nicole S., Waltner, Olivia G., Ensbey, Kathleen S., Schmidt, Christine R., Bhise, Shruti S., Furlan, Scott N. and Hill, Geoffrey R. (2022). CD8 T cells display distinct trajectories of T cell exhaustion in the bone marrow of mice with multiple myeloma. Annual Meeting of the American-Association-for-Cancer-Research (AACR), New Orleans La, Apr 08-13, 2022. PHILADELPHIA: AMER ASSOC CANCER RESEARCH.

CD8 T cells display distinct trajectories of T cell exhaustion in the bone marrow of mice with multiple myeloma

2022

Conference Publication

Stromal cell derived IL6 inhibits the extrinsic apoptotic pathway in multiple myeloma cell lines

Ackley, James C., McCachren, Samuel, Lonial, Sagar, Green, Damien J., Riddell, Stanley R., Hill, Geoffrey R., Dhodapkar, Madhav V. and Boise, Lawrence H. (2022). Stromal cell derived IL6 inhibits the extrinsic apoptotic pathway in multiple myeloma cell lines. Annual Meeting of the American-Association-for-Cancer-Research (AACR), New Orleans La, Apr 08-13, 2022. PHILADELPHIA: AMER ASSOC CANCER RESEARCH.

Stromal cell derived IL6 inhibits the extrinsic apoptotic pathway in multiple myeloma cell lines