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2019 Conference Publication Inhibiting EZH2 function prevents and treats chronic graft vs host disease (cGVHD) by disrupting germinal center formation and plasma cell maturationZaiken, Michael C., Flynn, Ryan, Paz, Katelyn, Rhee, Stephanie, Park, Paul, Hemming, Matthew, Sage, Peter, Sharpe, Arlene, Luznik, Leonard, Mailard, Ivan, Hill, Geoffrey R., MacDonald, Kelli, Serody, Jonathon, Cutler, Corey, Koreth, John, Miklos, David, Antin, Joseph, Soiffer, Robert, Ritz, Jerome, Bradner, Jay, Qi, Jun and Blazar, Bruce R. (2019). Inhibiting EZH2 function prevents and treats chronic graft vs host disease (cGVHD) by disrupting germinal center formation and plasma cell maturation. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.42 |
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2019 Conference Publication Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathologyKoyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce R., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.38 |
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2019 Conference Publication B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethalitySaha, Asim, Taylor, Patricia A., Lees, Christopher J., Panoskaltsis-Mortari, Angela, Osborn, Mark J., Feser, Colby J., Thangavelu, Govindarajan, Melchinger, Wolfgang, Refaeli, Yosef, Hill, Geoffrey R., Munn, David H., Serody, Jonathan S., Maillard, Ivan, Kreymborg, Katharina, van den Brink, Marcel, Dong, Chen, Huang, Shuyu, Zang, Xingxing, Allison, James P, Zeiser, Robert and Blazar, Bruce R. (2019). B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.10 |
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2019 Journal Article Effect of plasmapheresis on ATG (Thymoglobulin) clearance prior to adoptive T cell transferZhang, Ping, Curley, Cameron I., Mudie, Kari, Nakagaki, Midori, Hill, Geoffrey R., Roberts, Jason A. and Tey, Siok-Keen (2019). Effect of plasmapheresis on ATG (Thymoglobulin) clearance prior to adoptive T cell transfer. Bone Marrow Transplantation, 54 (12), 2110-2116. doi: 10.1038/s41409-019-0505-5 |
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2019 Journal Article Expansion of IL-17A-secreting CD8 + mucosa-associated invariant T cells in peripheral blood following stem cell mobilizationVarelias, Antiopi, Gartlan, Kate H., Wilkinson, Andrew N., Olver, Stuart D., Samson, Luke D., Tey, Siok-Keen, MacDonald, Kelli P. A. and Hill, Geoffrey R. (2019). Expansion of IL-17A-secreting CD8 + mucosa-associated invariant T cells in peripheral blood following stem cell mobilization. Blood Advances, 3 (5), 718-723. doi: 10.1182/bloodadvances.2018025601 |
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2019 Journal Article Phase I trial of inducible caspase 9 T cells in adult stem cell transplant demonstrates massive clonotypic proliferative potential and long-term persistence of transgenic T cellsZhang, Ping, Raju, Jyothy, Ullah, Md Ashik, Au, Raymond, Varelias, Antiopi, Gartlan, Kate H, Olver, Stuart D., Samson, Luke D., Sturgeon, Elise, Zomerdijk, Nienke, Avery, Judy, Gargett, Tessa, Brown, Michael P., Coin, Lachlan J., Ganesamoorthy, Devika, Hutchins, Cheryl, Pratt, Gary R, Kennedy, Glen A., Morton, A. James, Curley, Cameron I., Hill, Geoffrey R. and Tey, Siok-Keen (2019). Phase I trial of inducible caspase 9 T cells in adult stem cell transplant demonstrates massive clonotypic proliferative potential and long-term persistence of transgenic T cells. Clinical Cancer Research, 25 (6), 1749-1755. doi: 10.1158/1078-0432.CCR-18-3069 |
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2019 Journal Article Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantationMartins, Jose Paulo, Andoniou, Christopher E., Fleming, Peter, Kuns, Rachel D., Schuster, Iona S., Voigt, Valentina, Daly, Sheridan, Varelias, Antiopi, Tey, Siok-Keen, Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation. Science, 363 (6424), 288-293. doi: 10.1126/science.aat0066 |
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2019 Journal Article Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host diseasePaz, Katelyn, Flynn, Ryan, Du, Jing, Qi, Jun, Luznik, Leo, Maillard, Ivan, MacDonald, Kelli P., Hill, Geoffrey R., Serody, Jonathan S., Murphy, William J., Sage, Peter T., Sharpe, Arlene H., Miklos, David, Cutler, Corey S., Koreth, John, Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Bradner, James E., Melnick, Ari M. and Blazar, Bruce R. (2019). Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease. Blood, 133 (1), 94-99. doi: 10.1182/blood-2018-03-839993 |
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2019 Journal Article Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host diseasePaz, Katelyn, Flynn, Ryan, Du, Jing, Tannheimer, Stacey, Johnson, Amy J., Dong, Shuai, Stark, Anne-Katrien, Okkenhaug, Klaus, Panoskaltsis-Mortari, Angela, Sage, Peter T., Sharpe, Arlene H., Luznik, Leo, Ritz, Jerome, Soiffer, Robert J., Cutler, Corey S., Koreth, John, Antin, Joseph H., Miklos, David B., MacDonald, Kelli P., Hill, Geoffrey R., Maillard, Ivan, Serody, Jonathan S., Murphy, William J., Munn, David H., Feser, Colby, Zaiken, Michael, Vanhaesebroeck, Bart, Turka, Laurence A., Byrd, John C. and Blazar, Bruce R. (2019). Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease. American Journal of Transplantation, 19 (6) ajt.15305, 1820-1830. doi: 10.1111/ajt.15305 |
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2018 Journal Article Distinct roles for CD4+ Foxp3+ regulatory T cells and IL-10–mediated immunoregulatory mechanisms during experimental visceral Leishmaniasis caused by Leishmania donovaniBunn, Patrick T., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Kumar, Rajiv, Ng, Susanna S., Edwards, Chelsea L., Faleiro, Rebecca J., Sheel, Meru, Amante, Fiona H., Frame, Teija C. M., Muller, Werner, Haque, Ashraful, Uzonna, Jude E., Hill, Geoffrey R. and Engwerda, Christian R. (2018). Distinct roles for CD4+ Foxp3+ regulatory T cells and IL-10–mediated immunoregulatory mechanisms during experimental visceral Leishmaniasis caused by Leishmania donovani. The Journal of Immunology, 201 (11), 3362-3372. doi: 10.4049/jimmunol.1701582 |
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2018 Book Chapter Monocytes, macrophages, and dendritic cellsCollin, Matthew and Hill, Geoffrey R. (2018). Monocytes, macrophages, and dendritic cells. Wintrobe's Clinical Hematology: Fourteenth Edition. (pp. 616-683) Philadelphia, PA United States: Wolters Kluwer. |
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2018 Journal Article Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammationJacquelin, Sebastien, Straube, Jasmin, Cooper, Leanne, Vu, Therese, Song, Axia, Bywater, Megan, Baxter, Eva, Heidecker, Matthew, Wackrow, Brad, Porter, Amy, Ling, Victoria, Green, Joanne, Austin, Rebecca, Kazakoff, Stephen, Waddell, Nicola, Hesson, Luke B., Pimanda, John E., Stegelmann, Frank, Bullinger, Lars, Döhner, Konstanze, Rampal, Raajit K., Heckl, Dirk, Hill, Geoffrey R. and Lane, Steven W. (2018). Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation. Blood, 132 (26), blood-2018. doi: 10.1182/blood-2018-04-846220 |
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2018 Journal Article Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockadeMinnie, Simone A., Kuns, Rachel D., Gartlan, Kate H., Zhang, Ping, Wilkinson, Andrew N., Samson, Luke, Guillerey, Camille, Engwerda, Christian, MacDonald, Kelli P. A., Smyth, Mark J., Markey, Kate A., Vuckovic, Slavica and Hill, Geoffrey R. (2018). Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockade. Blood, 132 (16), 1675-1688. doi: 10.1182/blood-2018-01-825240 |
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2018 Journal Article Bone marrow transplantation generates T cell–dependent control of myeloma in miceVuckovic, Slavica, Minnie, Simone A., Smith, David, Gartlan, Kate H., Watkins, Thomas S., Markey, Kate A., Mukhopadhyay, Pamela, Guillerey, Camille, Kuns, Rachel D., Locke, Kelly R., Pritchard, Antonia L., Johansson, Peter A., Varelias, Antiopi, Zhang, Ping, Huntington, Nicholas D., Waddell, Nicola, Chesi, Marta, Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Bone marrow transplantation generates T cell–dependent control of myeloma in mice. Journal of Clinical Investigation, 129 (1) CI98888, 106-121. doi: 10.1172/jci98888 |
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2018 Conference Publication Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter StudyZomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878 |
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2018 Conference Publication Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter StudyZomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878 |
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2018 Journal Article TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myelomaGuillerey, Camille, Harjunpää, Heidi, Carrié, Nadège, Kassem, Sahar, Teo, Tricia, Miles, Kim, Krumeich, Sophie, Weulersse, Marianne, Cuisinier, Marine, Stannard, Kimberley, Yu, Yuan, Minnie, Simone A., Hill, Geoffrey R., Dougall, William C., Avet-Loiseau, Hervé, Teng, Michele W. L., Nakamura, Kyohei, Martinet, Ludovic and Smyth, Mark J. (2018). TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myeloma. Blood, 132 (16), blood-2018. doi: 10.1182/blood-2018-01-825265 |
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2018 Journal Article Immune regulatory cell infusion for graft-versus-host disease prevention and therapyBlazar, Bruce R., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2018). Immune regulatory cell infusion for graft-versus-host disease prevention and therapy. Blood, 131 (24), 2651-2660. doi: 10.1182/blood-2017-11-785865 |
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2018 Journal Article Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host diseaseTakahashi, Shuichiro, Hashimoto, Daigo, Hayase, Eiko, Ogasawara, Reiki, Ohigashi, Hiroyuki, Ara, Takahide, Yokoyama, Emi, Ebata, Ko, Matsuoka, Satomi, Hill, Geoffrey R., Sugita, Junichi, Onozawa, Masahiro and Teshima, Takanori (2018). Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease. Blood, 131 (18), 2074-2085. doi: 10.1182/blood-2017-06-792614 |
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2018 Conference Publication Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In VivoWilkinson, Andrew N., Kuns, Rachel D., Varelias, Antiopi, Vuckovic, Slavica, Rose-John, Stefan, Gartlan, Kate H. and Hill, Geoffrey R. (2018). Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.2 |
