2018 Journal Article Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammationJacquelin, Sebastien, Straube, Jasmin, Cooper, Leanne, Vu, Therese, Song, Axia, Bywater, Megan, Baxter, Eva, Heidecker, Matthew, Wackrow, Brad, Porter, Amy, Ling, Victoria, Green, Joanne, Austin, Rebecca, Kazakoff, Stephen, Waddell, Nicola, Hesson, Luke B., Pimanda, John E., Stegelmann, Frank, Bullinger, Lars, Döhner, Konstanze, Rampal, Raajit K., Heckl, Dirk, Hill, Geoffrey R. and Lane, Steven W. (2018). Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation. Blood, 132 (26), blood-2018. doi: 10.1182/blood-2018-04-846220 |
2018 Journal Article Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockadeMinnie, Simone A., Kuns, Rachel D., Gartlan, Kate H., Zhang, Ping, Wilkinson, Andrew N., Samson, Luke, Guillerey, Camille, Engwerda, Christian, MacDonald, Kelli P. A., Smyth, Mark J., Markey, Kate A., Vuckovic, Slavica and Hill, Geoffrey R. (2018). Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockade. Blood, 132 (16), 1675-1688. doi: 10.1182/blood-2018-01-825240 |
2018 Journal Article Bone marrow transplantation generates T cell–dependent control of myeloma in miceVuckovic, Slavica, Minnie, Simone A., Smith, David, Gartlan, Kate H., Watkins, Thomas S., Markey, Kate A., Mukhopadhyay, Pamela, Guillerey, Camille, Kuns, Rachel D., Locke, Kelly R., Pritchard, Antonia L., Johansson, Peter A., Varelias, Antiopi, Zhang, Ping, Huntington, Nicholas D., Waddell, Nicola, Chesi, Marta, Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Bone marrow transplantation generates T cell–dependent control of myeloma in mice. Journal of Clinical Investigation, 129 (1) CI98888, 106-121. doi: 10.1172/jci98888 |
2018 Conference Publication Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter StudyZomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878 |
2018 Conference Publication Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter StudyZomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878 |
2018 Journal Article TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myelomaGuillerey, Camille, Harjunpää, Heidi, Carrié, Nadège, Kassem, Sahar, Teo, Tricia, Miles, Kim, Krumeich, Sophie, Weulersse, Marianne, Cuisinier, Marine, Stannard, Kimberley, Yu, Yuan, Minnie, Simone A., Hill, Geoffrey R., Dougall, William C., Avet-Loiseau, Hervé, Teng, Michele W. L., Nakamura, Kyohei, Martinet, Ludovic and Smyth, Mark J. (2018). TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myeloma. Blood, 132 (16), blood-2018. doi: 10.1182/blood-2018-01-825265 |
2018 Journal Article Immune regulatory cell infusion for graft-versus-host disease prevention and therapyBlazar, Bruce R., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2018). Immune regulatory cell infusion for graft-versus-host disease prevention and therapy. Blood, 131 (24), 2651-2660. doi: 10.1182/blood-2017-11-785865 |
2018 Journal Article Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host diseaseTakahashi, Shuichiro, Hashimoto, Daigo, Hayase, Eiko, Ogasawara, Reiki, Ohigashi, Hiroyuki, Ara, Takahide, Yokoyama, Emi, Ebata, Ko, Matsuoka, Satomi, Hill, Geoffrey R., Sugita, Junichi, Onozawa, Masahiro and Teshima, Takanori (2018). Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease. Blood, 131 (18), 2074-2085. doi: 10.1182/blood-2017-06-792614 |
2018 Conference Publication Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibriumMinnie, Simone, Vuckovic, Slavica, Smith, David, Gartlan, Kate H., Watkins, Thomas S., Kuns, Rachel D., Guillerey, Camille, Chesi, Marta, Markey, Kate A., Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.19 |
2018 Conference Publication Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colonVarelias, Antiopi, Bunting, Mark, Ormerod, Kate, Koyama, Motoko, Olver, Stuart, Straube, Jasmin, Kuns, Rachel, Robb, Renee, Henden, Andrea, Cooper, Leanne, Lachner, Nancy, Gartlan, Kate, Lantz, Olivier J., Kjer-Nielsen, Lars, Mak, Jeffrey, Fairlie, David, Clouston, Andrew, McCluskey, James, Rossjohn, Jamie, Lane, Steven, Hugenholtz, Phil and Hill, Geoff (2018). Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.15 |
2018 Conference Publication Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In VivoWilkinson, Andrew N., Kuns, Rachel D., Varelias, Antiopi, Vuckovic, Slavica, Rose-John, Stefan, Gartlan, Kate H. and Hill, Geoffrey R. (2018). Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.2 |
2018 Journal Article Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onsetHülsdünker, Jan, Ottmüller, Katja J., Neeff, Hannes P., Koyama, Motoko, Gao, Zhan, Thomas, Oliver S., Follo, Marie, Al-Ahmad, Ali, Prinz, Gabriele, Duquesne, Sandra, Dierbach, Heide, Kirschnek, Susanne, Lämmermann, Tim, Blaser, Martin J., Fife, Brian T., Blazar, Bruce R., Beilhack, Andreas, Hill, Geoffrey R., Häcker, Georg and Zeiser, Robert (2018). Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood, 131 (16), 1858-1869. doi: 10.1182/blood-2017-10-812891 |
2018 Journal Article Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cellsMathew, Nimitha R, Baumgartner, Francis, Braun, Lukas, O'Sullivan, David, Thomas, Simone, Waterhouse, Miguel, Müller, Tony A, Hanke, Kathrin, Taromi, Sanaz, Apostolova, Petya, Illert, Anna L, Melchinger, Wolfgang, Duquesne, Sandra, Schmitt-Graeff, Annette, Osswald, Lena, Yan, Kai-Li, Weber, Arnim, Tugues, Sonia, Spath, Sabine, Pfeifer, Dietmar, Follo, Marie, Claus, Rainer, Lübbert, Michael, Rummelt, Christoph, Bertz, Hartmut, Wäsch, Ralph, Haag, Johanna, Schmidts, Andrea, Schultheiss, Michael ... Zeiser, Robert (2018). Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine, 24 (4), 526-526. doi: 10.1038/nm0418-526c |
2018 Journal Article Recipient mucosal-associated invariant T cells control GVHD within the colonVarelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y. W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill, Geoffrey R. (2018). Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation, 128 (5), 1919-1936. doi: 10.1172/JCI91646 |
2018 Journal Article Granulocytes are unresponsive to IL-6 due to an absence of gp130Wilkinson, Andrew N., Gartlan, Kate H., Kelly, Greg, Samson, Luke D., Olver, Stuart D., Avery, Judy, Zomerdijk, Nienke, Tey, Siok-Keen, Lee, Jason S., Vuckovic, Slavica and Hill, Geoffrey R. (2018). Granulocytes are unresponsive to IL-6 due to an absence of gp130. Journal of Immunology, 200 (9), 3547-3555. doi: 10.4049/jimmunol.1701191 |
2018 Journal Article Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipientsHardy, Kristine, Smith, Corey, Tu, Wen Juan, McCuaig, Robert, Panikkar, Archana, Dasari, Vijayendra, Wu, Fan, Tey, Siok-Keen, Hill, Geoffrey R., Khanna, Rajiv and Rao, Sudha (2018). Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients. Blood Advances, 2 (6), 656-668. doi: 10.1182/bloodadvances.2018015909 |
2018 Journal Article Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMTMarkey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Lane, Steven W. and Hill, Geoffrey R. (2018). Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT. Bone Marrow Transplantation, 53 (6), 800-803. doi: 10.1038/s41409-018-0148-y |
2018 Journal Article The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemiaStraube, Jasmin, Ling, Victoria Y, Hill, Geoffrey R and Lane, Steven W (2018). The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia. Blood, 131 (10), 1148-1153. doi: 10.1182/blood-2017-09-807438 |
2018 Journal Article Early blood stream infection after BMT is associated with cytokine dysregulation and poor overall survivalCatchpoole, Elizabeth M., Thirunavukarasu, Caitlin E., Varelias, Antiopi, Schlebusch, Sanmarié, Olver, Stuart, Zomerdijk, Nienke, Osland, Emma, Kennedy, Glen A., Tey, Siok-Keen, Hill, Geoffrey R. and Markey, Kate A. (2018). Early blood stream infection after BMT is associated with cytokine dysregulation and poor overall survival. Biology of Blood and Marrow Transplantation, 24 (7), 1360-1366. doi: 10.1016/j.bbmt.2018.02.025 |
2018 Journal Article Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cellsMathew, Nimitha R., Baumgartner, Francis, Braun, Lukas, O'Sullivan, David, Thomas, Simone, Waterhouse, Miguel, Müller, Tony A., Hanke, Kathrin, Taromi, Sanaz, Apostolova, Petya, Illert, Anna L., Melchinger, Wolfgang, Duquesne, Sandra, Schmitt-Graeff, Annette, Osswald, Lena, Yan, Kai-Li, Weber, Arnim, Tugues, Sonia, Spath, Sabine, Pfeifer, Dietmar, Follo, Marie, Claus, Rainer, Lübbert, Michael, Rummelt, Christoph, Bertz, Hartmut, Wäsch, Ralph, Haag, Johanna, Schmidts, Andrea, Schultheiss, Michael ... Zeiser, Robert (2018). Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine, 24 (3), 282-291. doi: 10.1038/nm.4484 |