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2020

Journal Article

Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels

Zhang, Xuexin, Xin, Ping, Yoast, Ryan E., Emrich, Scott M., Johnson, Martin T., Pathak, Trayambak, Benson, J. Cory, Azimi, Iman, Gill, Donald L., Monteith, Gregory R. and Trebak, Mohamed (2020). Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels. Cell Calcium, 91 102281, 102281. doi: 10.1016/j.ceca.2020.102281

Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels

2020

Journal Article

Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy

Taylor, Jack, Azimi, Iman, Monteith, Gregory and Bebawy, Mary (2020). Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy. Journal of Extracellular Vesicles, 9 (1) 1734326, 1734326. doi: 10.1080/20013078.2020.1734326

Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy

2020

Journal Article

Assessment of doxorubicin-induced remodeling of Ca2+ signaling and associated Ca2+ regulating proteins in MDA-MB-231 breast cancer cells

Bong, Alice H.L., Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Assessment of doxorubicin-induced remodeling of Ca2+ signaling and associated Ca2+ regulating proteins in MDA-MB-231 breast cancer cells. Biochemical and Biophysical Research Communications, 522 (2), 532-538. doi: 10.1016/j.bbrc.2019.11.136

Assessment of doxorubicin-induced remodeling of Ca2+ signaling and associated Ca2+ regulating proteins in MDA-MB-231 breast cancer cells

2020

Journal Article

Transient receptor potential cation channel subfamily V and breast cancer

So, Choon Leng, Milevskiy, Michael J. G. and Monteith, Gregory R. (2020). Transient receptor potential cation channel subfamily V and breast cancer. Laboratory Investigation, 100 (2), 199-206. doi: 10.1038/s41374-019-0348-0

Transient receptor potential cation channel subfamily V and breast cancer

2020

Journal Article

Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuli

Stewart, Teneale A., Azimi, Iman, Marcial, Daneth, Peters, Amelia A., Chalmers, Silke B., Yapa, Kunsala T. D. S, Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuli. Laboratory Investigation, 100 (2), 224-233. doi: 10.1038/s41374-019-0280-3

Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuli

2019

Journal Article

NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin

Bong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin. Molecular Oncology, 14 (1) 1878-0261.12589, 87-104. doi: 10.1002/1878-0261.12589

NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin

2019

Journal Article

Calcium signalling and breast cancer

So, Choon Leng, Saunus, Jodi M., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). Calcium signalling and breast cancer. Seminars in Cell & Developmental Biology, 94, 74-83. doi: 10.1016/j.semcdb.2018.11.001

Calcium signalling and breast cancer

2019

Journal Article

The calcium-signaling toolkit in cancer: remodeling and targeting

Roberts-Thomson, Sarah J., Chalmers, Silke B. and Monteith, Gregory R. (2019). The calcium-signaling toolkit in cancer: remodeling and targeting. Cold Spring Harbor Perspectives in Biology, 11 (8) a035204, a035204. doi: 10.1101/cshperspect.a035204

The calcium-signaling toolkit in cancer: remodeling and targeting

2019

Journal Article

ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses

Azimi, Iman, Milevskiy, Michael J. G., Chalmers, Silke B., Yapa, Kunsala T. D. S., Robitaille, Mélanie, Henry, Christopher, Baillie, Gregory J., Thompson, Erik W., Roberts-Thomson, Sarah J and Monteith, Gregory R (2019). ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses. Cancers, 11 (2) 208, 208. doi: 10.3390/cancers11020208

ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses

2018

Journal Article

Pharmacological inhibition of store-operated calcium entry in MDA-MB-468 basal A breast cancer cells: consequences on calcium signalling, cell migration and proliferation

Azimi, Iman, Bong, Alice H., Poo, Greta X. H., Armitage, Kaela, Lok, Dawn, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). Pharmacological inhibition of store-operated calcium entry in MDA-MB-468 basal A breast cancer cells: consequences on calcium signalling, cell migration and proliferation. Cellular and Molecular Life Sciences, 75 (24), 4525-4537. doi: 10.1007/s00018-018-2904-y

Pharmacological inhibition of store-operated calcium entry in MDA-MB-468 basal A breast cancer cells: consequences on calcium signalling, cell migration and proliferation

2018

Journal Article

ORAI channels and cancer

Chalmers, Silke B. and Monteith, Gregory R. (2018). ORAI channels and cancer. Cell Calcium, 74, 160-167. doi: 10.1016/j.ceca.2018.07.011

ORAI channels and cancer

2018

Journal Article

An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assay

Stevenson, Ralph J, Azimi, Iman, Flanagan, Jack U, Inserra, Marco, Vetter, Irina, Monteith, Gregory R and Denny, William A (2018). An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assay. Bioorganic & Medicinal Chemistry, 26 (12), 3406-3413. doi: 10.1016/j.bmc.2018.05.012

An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assay

2018

Journal Article

An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells

Kaemmerer, Elke, Turner, Dane, Peters, Amelia A., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells. Journal of pharmacological and toxicological methods, 92, 13-19. doi: 10.1016/j.vascn.2018.02.005

An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells

2018

Journal Article

Calcium signaling and the therapeutic targeting of cancer cells

Bong, Alice H. L. and Monteith, Gregory R. (2018). Calcium signaling and the therapeutic targeting of cancer cells. Biochimica et Biophysica Acta, 1865 (11), 1786-1794. doi: 10.1016/j.bbamcr.2018.05.015

Calcium signaling and the therapeutic targeting of cancer cells

2018

Journal Article

Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells

Jamaludin, S. Y. N., Azimi, I., Davis, F. M., Peters, A. A., Gonda, T. J., Thompson, E. W., Roberts-Thomson, S. J. and Monteith, G. R. (2018). Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells. Oncology Letters, 15 (4), 4289-4295. doi: 10.3892/ol.2018.7827

Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells

2018

Journal Article

Assessment of the TRPM8 inhibitor AMTB in breast cancer cells and its identification as an inhibitor of voltage gated sodium channels

Yapa, Kunsala T. D. S., Deuis, Jennifer, Peters, Amelia A., Kenny, Paraic A., Roberts-Thomson, Sarah J., Vetter, Irina and Monteith, Gregory R. (2018). Assessment of the TRPM8 inhibitor AMTB in breast cancer cells and its identification as an inhibitor of voltage gated sodium channels. Life Sciences, 198, 128-135. doi: 10.1016/j.lfs.2018.02.030

Assessment of the TRPM8 inhibitor AMTB in breast cancer cells and its identification as an inhibitor of voltage gated sodium channels

2018

Journal Article

Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m

Bassett, John J., Bong, Alice H.L., Janke, Ellen K., Robitaille, Mélanie, Roberts-Thomson, Sarah J., Peters, Amelia A. and Monteith, Gregory R. (2018). Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m. Cell Calcium, 72, 39-50. doi: 10.1016/j.ceca.2018.02.003

Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m

2017

Journal Article

Hypoxia-induced reactive oxygen species mediate N-cadherin and SERPINE1 expression, EGFR signalling and motility in MDA-MB-468 breast cancer cells

Azimi, Iman, Petersen, Rosalie M., Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2017). Hypoxia-induced reactive oxygen species mediate N-cadherin and SERPINE1 expression, EGFR signalling and motility in MDA-MB-468 breast cancer cells. Scientific Reports, 7 (1) 15140, 1-11. doi: 10.1038/s41598-017-15474-7

Hypoxia-induced reactive oxygen species mediate N-cadherin and SERPINE1 expression, EGFR signalling and motility in MDA-MB-468 breast cancer cells

2017

Journal Article

TRPC1 is a differential regulator of hypoxia-mediated events and Akt signalling in PTEN-deficient breast cancer cells

Azimi, Iman, Milevskiy, Michael J. G., Kaemmerer, Elke, Turner, Dane, Yapa, Kunsala T. D. S., Brown, Melissa A., Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2017). TRPC1 is a differential regulator of hypoxia-mediated events and Akt signalling in PTEN-deficient breast cancer cells. Journal of Cell Science, 130 (14), 2292-2305. doi: 10.1242/jcs.196659

TRPC1 is a differential regulator of hypoxia-mediated events and Akt signalling in PTEN-deficient breast cancer cells

2017

Journal Article

Breast cancer cells: focus on the consequences of epithelial-to-mesenchymal transition

Bong, Alice H. L. and Monteith, Gregory R. (2017). Breast cancer cells: focus on the consequences of epithelial-to-mesenchymal transition. International Journal of Biochemistry & Cell Biology, 87 (33), 23-26. doi: 10.1016/j.biocel.2017.03.014

Breast cancer cells: focus on the consequences of epithelial-to-mesenchymal transition