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2024 Journal Article Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cellsSo, Choon Leng, Robitaille, Mélanie, Sadras, Francisco, McCullough, Michael H., Milevskiy, Michael J. G., Goodhill, Geoffrey J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells. Communications Biology, 7 (1) 467, 1-14. doi: 10.1038/s42003-024-06163-z |
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2022 Journal Article ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathwayBassett, John J., Robitaille, Mélanie, Peters, Amelia A., Bong, Alice H. L., Taing, Meng‐Wong, Wood, Ian A., Sadras, Francisco, Roberts‐Thomson, Sarah J. and Monteith, Gregory R. (2022). ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway. The FASEB Journal, 36 (1) e22108, e22108. doi: 10.1096/fj.202002031rr |
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2020 Journal Article A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functionsAzimi, Iman, Stevenson, Ralph J., Zhang, Xuexin, Meizoso-Huesca, Aldo, Xin, Ping, Johnson, Martin, Flanagan, Jack U., Chalmers, Silke B., Yoast, Ryan E., Kapure, Jeevak S., Ross, Benjamin P., Vetter, Irina, Ashton, Mark R., Launikonis, Bradley S., Denny, William A., Trebak, Mohamed and Monteith, Gregory R. (2020). A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functions. ACS Pharmacology and Translational Science, 3 (1) acsptsci.9b00081, 135-147. doi: 10.1021/acsptsci.9b00081 |
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2017 Journal Article Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cellsPeters, A. A., Jamaludin, S. Y. N., Yapa, K. T. D. S., Chalmers, S., Wiegmans, A. P., Lim, H. F., Milevskiy, M. J. G., Azimi, I., Davis, F. M., Northwood, K. S., Pera, E., Marcial, D. L., Dray, E., Waterhouse, N. J., Cabot, P. J., Gonda, T. J., Kenny, P. A., Brown, M. A., Khanna, K. K., Roberts-Thomson, S. J. and Monteith, G. R. (2017). Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells. Oncogene, 36 (46), 6490-6500. doi: 10.1038/onc.2017.234 |
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2017 Journal Article The calcium-cancer signalling nexusMonteith, Gregory R., Prevarskaya, Natalia and Roberts-Thomson, Sarah J. (2017). The calcium-cancer signalling nexus. Nature Reviews Cancer, 17 (6), 367-380. doi: 10.1038/nrc.2017.18 |
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2014 Journal Article Targeting EMT in cancer: opportunities for pharmacological interventionDavis, Felicity M., Stewart, Teneale A., Thompson, Erik W. and Monteith, Gregory R. (2014). Targeting EMT in cancer: opportunities for pharmacological intervention. Trends in Pharmacological Sciences, 35 (9), 479-488. doi: 10.1016/j.tips.2014.06.006 |
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2014 Journal Article Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependentDavis, F. M., Azimi, I., Faville, R. A., Peters, A. A., Jalink, K., Putney Jr, J. W., Goodhill, G. J., Thompson, E. W., Roberts-Thomson, S. J. and Monteith, G. R. (2014). Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent. Oncogene, 33 (18), 2307-2316. doi: 10.1038/onc.2013.187 |
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2010 Journal Article Store-independent activation of Orai1 by SPCA2 in mammary tumorsFeng, Mingye, Grice, Desma, Faddy, Helen, Nguyen, Nguyen, Leitch, Sharon, Wang, Yingyu, Muend, Sabina, Kenny, Paraic A, Sukumar, Saraswati, Roberts-Thomson, Sarah J., Monteith, Gregory R. and Rao, Rajini (2010). Store-independent activation of Orai1 by SPCA2 in mammary tumors. Cell, 143 (1), 84-98. doi: 10.1016/j.cell.2010.08.040 |
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2007 Journal Article Calcium and cancer: targeting Ca2+ transportMonteith, Gregory R., McAndrew, Damara, Faddy, Helen M. and Roberts-Thomson, Sarah J. (2007). Calcium and cancer: targeting Ca2+ transport. Nature Reviews Cancer, 7 (7), 519-530. doi: 10.1038/nrc2171 |
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2024 Journal Article TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cellsBong, Alice H. L., Robitaille, Mélanie, Lin, Sichun, McCart-Reed, Amy, Milevskiy, Michael, Angers, Stéphane, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells. Cell Death Discovery, 10 (1) 421, 1-12. doi: 10.1038/s41420-024-02183-0 |
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2023 Journal Article The intersection between cysteine proteases, Ca2+ signalling and cancer cell apoptosisHua, Trinh, Robitaille, Mélanie, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2023). The intersection between cysteine proteases, Ca2+ signalling and cancer cell apoptosis. Biochimica et Biophysica Acta - Molecular Cell Research, 1870 (7) 119532, 1-13. doi: 10.1016/j.bbamcr.2023.119532 |
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2023 Journal Article Intersection between calcium signalling and epithelial-mesenchymal plasticity in the context of cancerJanke, Ellen K., Chalmers, Silke B., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2023). Intersection between calcium signalling and epithelial-mesenchymal plasticity in the context of cancer. Cell Calcium, 112 102741, 1-9. doi: 10.1016/j.ceca.2023.102741 |
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2023 Journal Article TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluidsSo, Choon Leng, Robitaille, Mélanie and Monteith, Gregory R. (2023). TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluids. Cell Calcium, 109 102685, 1-3. doi: 10.1016/j.ceca.2022.102685 |
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2022 Journal Article AKT regulation of ORAI1-mediated calcium influx in breast cancer cellsBong, Alice Hui Li, Hua, Trinh, So, Choon Leng, Peters, Amelia A., Robitaille, Mélanie, Tan, Yin Yi, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2022). AKT regulation of ORAI1-mediated calcium influx in breast cancer cells. Cancers, 14 (19) 4794, 1-14. doi: 10.3390/cancers14194794 |
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2022 Journal Article Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cellsSo, Choon Leng, Meinert, Christoph, Xia, Qing, Robitaille, Mélanie, Roberts-Thomson, Sarah J and Monteith, Gregory R (2022). Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cells. Cell Calcium, 104 102569, 1-10. doi: 10.1016/j.ceca.2022.102569 |
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2022 Journal Article ORAI1-regulated gene expression in breast cancer cells: Roles for STIM1 binding, calcium influx and transcription factor translocationRobitaille, Mélanie, Chan, Shao Ming, Peters, Amelia A., Dai, Limin, So, Choon Leng, Bong, Alice H. L., Sadras, Francisco, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2022). ORAI1-regulated gene expression in breast cancer cells: Roles for STIM1 binding, calcium influx and transcription factor translocation. International Journal of Molecular Sciences, 23 (11) 5867, 1-14. doi: 10.3390/ijms23115867 |
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2022 Journal Article Uncoiling the link between STIM1 and metastatic pathways in estrogen receptor negative breast cancer cellsMonteith, Prof. Gregory R, Robitaille, Mélanie and Roberts-Thomson, Sarah J. (2022). Uncoiling the link between STIM1 and metastatic pathways in estrogen receptor negative breast cancer cells. Cell Calcium, 103 102563, 102563. doi: 10.1016/j.ceca.2022.102563 |
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2021 Journal Article An emerging role for calcium signaling in cancer-associated fibroblastsSadras, Francisco, Monteith, Gregory R. and Roberts-Thomson, Sarah J. (2021). An emerging role for calcium signaling in cancer-associated fibroblasts. International Journal of Molecular Sciences, 22 (21) 11366, 1-11. doi: 10.3390/ijms222111366 |
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2021 Journal Article Altered calcium influx pathways in cancer-associated fibroblastsSadras, Francisco, Stewart, Teneale A., Robitaille, Mélanie, Peters, Amelia A., Croft, Priyakshi Kalita-de, Soon, Patsy S., Saunus, Jodi M., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2021). Altered calcium influx pathways in cancer-associated fibroblasts. Biomedicines, 9 (6) 680, 1-13. doi: 10.3390/biomedicines9060680 |
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2020 Journal Article Activation of the ion channel TRPV4 induces epithelial to mesenchymal transition in breast cancer cellsAzimi, Iman, Robitaille, Mélanie, Armitage, Kaela, So, Choon Leng, Milevskiy, Michael J. G., Northwood, Korinne, Lim, Huai Fang, Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Activation of the ion channel TRPV4 induces epithelial to mesenchymal transition in breast cancer cells. International Journal of Molecular Sciences, 21 (24) 9417, 1-14. doi: 10.3390/ijms21249417 |
