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2004 Journal Article Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitroRussell, F. D., Kearns, P., Toth, I. and Molenaar, P. (2004). Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitro. Journal of Pharmacology And Experimental Therapeutics, 310 (1), 209-214. doi: 10.1124/jpet.104.065425 |
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2004 Journal Article Cardiovascular actions of human urotensin II - considerations for hypertensionRussell, F. D. and Molenaar, P. (2004). Cardiovascular actions of human urotensin II - considerations for hypertension. Naunyn-Schmiedebergs Archives of Pharmacology, 369 (3), 271-273. doi: 10.1007/s00210-004-0876-y |
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2004 Journal Article Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failureBrattelid, T, Qvigstad, E, Lynham, JA, Molenaar, P, Aass, H, Geiran, O, Skomedal, T, Osnes, JB, Levy, FO and Kaumann, AJ (2004). Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure. Naunyn-Schmiedeberg's Arch Pharmacol, 370 (3), 157-166. doi: 10.1007/s00210-004-0963-0 |
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2004 Journal Article Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heartRussell, FD and Molenaar, P (2004). Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart. Cardiovascular Research, 63 (4), 673-681. doi: 10.1016/j.cardiores.2004.05.009 |
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2003 Journal Article Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptorsJoseph, Shirin S., Lynham, James A., Molenaar, Peter, Grace, Andrew A., Colledge, William H. and Kaumann, Alberto J. (2003). Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptors. Naunyn-Schmiedeberg's Archives of Pharmacology, 368 (6), 496-503. doi: 10.1007/s00210-003-0835-z |
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2003 Journal Article (-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptorSarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., Li, Li, Kaumann, Alberto J. and Molenaar, Peter (2003). (-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor. Naunyn-Schmiedeberg's Archives of Pharmacology, 367 (1), 10-21. doi: 10.1007/s00210-002-0652-9 |
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2003 Journal Article Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failureRussell, F. D., Meyers, D. E., Galbraith, A., Bett, N., Toth, I., Kearns, P. S. and Molenaar, P. (2003). Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. American Journal of Physiology - Heart & Circulatory Physiology, 285 (Oct.2003), H1576-H1581. doi: 10.1152/ajpheart.00217.2003 |
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2003 Journal Article The 'state' of beta-adrenoceptorsMolenaar, P. (2003). The 'state' of beta-adrenoceptors. British Journal of Pharmacology, 140 (1), 1-2. doi: 10.1038/sj.bjp.0705420 |
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2002 Journal Article Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitroMolenaar, P., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L., West, M. J. and Russell, F. D. (2002). Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro. Journal of The American College of Cardiology, 40 (7), 1275-1282. doi: 10.1016/S0735-1097(02)02137-X |
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2002 Journal Article (-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.Kaumann, AJ, Lynham, JA, Joseph, SS, Colledge, WH, Grace, AA and Molenaar, P (2002). (-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.. British Journal of Pharmacology, 135 |
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2001 Journal Article Cardiostimulant effects of urotensin-II in human heart in vitroRussell, FD, Molenaar, P and O'Brien, DM (2001). Cardiostimulant effects of urotensin-II in human heart in vitro. British Journal of Pharmacology, 132 (1), 5-9. doi: 10.1038/sj.bjp.0703811 |
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2001 Journal Article Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptorHeubach, J. F., Graf, E. M., Molenaar, P., Jager, A., Schroder, F., Herzig, S., Harding, S. E. and Ravens, U. (2001). Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor. British Journal of Pharmacology, 133 (1), 73-82. doi: 10.1038/sj.bjp.0704045 |
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2001 Journal Article Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacologyKaumann, AJ, Engelhardt, S, Hein, L, Molenaar, P and Lohse, M (2001). Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacology. Naunyn-schmiedebergs Archives of Pharmacology, 363 (1), 87-93. doi: 10.1007/s002100000336 |
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2000 Journal Article Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-proteinMolenaar, P., Bartel, S., Cochrane, A., Vetter, D., Jalali, H., Pohlner, P., Burrell, K., Karczewski, P, Krause, E. and Kaumann, A. J. (2000). Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein. Circulation, 102 (15), 1814-1821. doi: 10.1161/01.CIR.102.15.1814 |
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2000 Journal Article Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout miceOostendorp, J., Preitner, F., Moffatt, J., Jimenez, M., Giacobino, J. P., Molenaar, P. and Kaumann, A. J. (2000). Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout mice. British Journal of Pharmacology, 130 (4), 747-758. doi: 10.1038/sj.bjp.0703365 |
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2000 Journal Article Quantitative analysis of vascular to cardiac selectivity of L- and T-type voltage-operated calcium channel antagonists in human tissuesAngus, J, Sarsero, D, Fujiwara, T, Molenaar, P and Xi, Q (2000). Quantitative analysis of vascular to cardiac selectivity of L- and T-type voltage-operated calcium channel antagonists in human tissues. Clinical And Experimental Pharmacology And Physiology, 27 (12), 1019-1021. doi: 10.1046/j.1440-1681.2000.03369.x |
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2000 Journal Article The human heart endothelin system: ET-1 synthesis, storage, release and effectRussell, F. D. and Molenaar, P. (2000). The human heart endothelin system: ET-1 synthesis, storage, release and effect. Trends in Pharmacological Sciences, 21 (9), 353-359. doi: 10.1016/S0165-6147(00)01524-8 |
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2000 Journal Article Contractile and arrhythmic effects of endothelin receptor agonists in human heart in vitro: Blockade with SB 209670Burrell, K. M., Molenaar, P., Dawson, P. J. and Kaumann, A. J. (2000). Contractile and arrhythmic effects of endothelin receptor agonists in human heart in vitro: Blockade with SB 209670. Journal of Pharmacology and Experimental Therapeutics, 292 (1), 449-459. |
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1999 Journal Article Putative beta(4)-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[H-3]-CGP 12177 bindingSarsero, D., Molenaar, P., Kaumann, A. J. and Freestone, N. S. (1999). Putative beta(4)-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[H-3]-CGP 12177 binding. British Journal of Pharmacology, 128 (7), 1445-1460. doi: 10.1038/sj.bjp.0702936 |
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1999 Journal Article Activation of beta(2)-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failureKaumann, A, Bartel, S, Molenaar, P, Sanders, L, Burrell, K, Vetter, D, Hempel, P, Karczewski, P and Krause, EG (1999). Activation of beta(2)-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure. Circulation, 99 (1), 65-72. |
