2018 Journal Article Optimising treatment for severe asthmaUpham, John W. and Chung, Li Ping (2018). Optimising treatment for severe asthma. Medical Journal of Australia, 209 (2 Suppl), S22-S27. doi: 10.5694/mja18.00175 |
2018 Journal Article Sputum cytology during late-phase responses to inhalation challenge with different allergensRevez, J. A., Killian, K. J., O'Byrne, P. M., Boulet, L-P., Upham, J. W., Gauvreau, G. M. and Ferreira, M. A. R. (2018). Sputum cytology during late-phase responses to inhalation challenge with different allergens. Allergy, 73 (7), 1470-1478. doi: 10.1111/all.13415 |
2018 Journal Article PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ productionWerder, Rhiannon B., Lynch, Jason P., Simpson, Jennifer C., Zhang, Vivian, Hodge, Nick H., Poh, Matthew, Forbes-Blom, Elizabeth, Kulis, Christina, Smythe, Mark L., Upham, John W., Spann, Kirsten, Everard, Mark L. and Phipps, Simon (2018). PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production. Science Translational Medicine, 10 (440) eaao0052, eaao0052. doi: 10.1126/scitranslmed.aao0052 |
2018 Journal Article Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunityWerder, Rhiannon B, Zhang, Vivian, Lynch, Jason P, Snape, Natale, Upham, John W, Spann, Kirsten and Phipps, Simon (2018). Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity. The Journal of allergy and clinical immunology, 141 (5), 1607-1619.e9. doi: 10.1016/j.jaci.2017.07.051 |
2018 Journal Article Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profilesChen, Alice C. -H., Pena, Olga M., Nel, Hendrik J., Yerkovich, Stephanie T., Chang, Anne B., Baines, Katherine J., Gibson, Peter G., Petsky, Helen L., Pizzutto, Susan J., Hodge, Sandra, Masters, Ian B., Buntain, Helen L. and Upham, John W. (2018). Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles. Pediatric Pulmonology, 53 (5), 575-582. doi: 10.1002/ppul.23984 |
2018 Journal Article Working while unwell: Workplace impairment in people with severe asthmaHiles, S. A., Harvey, E. S., McDonald, V. M., Peters, M., Bardin, P., Reynolds, P. N., Upham, J. W., Baraket, M., Bhikoo, Z., Bowden, J., Brockway, B., Chung, L. P., Cochrane, B., Foxley, G., Garrett, J., Hew, M., Jayaram, L., Jenkins, C., Katelaris, C., Katsoulotos, G., Koh, M. S., Kritikos, V., Lambert, M., Langton, D., Rivero, A. L., Marks, G. B., Middleton, P. G., Nanguzgambo, A., Radhakrishna, N. ... Gibson, P. G. (2018). Working while unwell: Workplace impairment in people with severe asthma. Clinical and Experimental Allergy, 48 (6), 650-662. doi: 10.1111/cea.13153 |
2018 Journal Article Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitisChen, Alice C. -H., Tran, Hai B., Xi, Yang, Yerkovich, Stephanie T., Baines, Katherine J., Pizzutto, Susan J., Carroll, Melanie, Robertson, Avril A. B., Cooper, Matthew A., Schroder, Kate, Simpson, Jodie L., Gibson, Peter G., Hodge, Greg, Masters, Ian B., Buntain, Helen M., Petsky, Helen L., Prime, Samantha J., Chang, Anne B., Hodge, Sandra and Upham, John W. (2018). Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis. ERJ Open Research, 4 (1) 00130-2017, 00130-2017. doi: 10.1183/23120541.00130-2017 |
2017 Journal Article Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansionLynch, Jason P., Werder, Rhiannon B., Loh, Zhixuan, Sikder, Md Al Amin, Curren, Bodie, Zhang, Vivian, Rogers, Matthew J. , Lane, Katie, Simpson, Jennifer, Mazzone, Stuart B., Spann, Kirsten, Hayball, John, Diener, Kerrilyn, Everard, Mark L., Blyth, Christopher C., Forstner, Christian, Dennis, Paul G., Murtaza, Nida, Morrison, Mark, Ó Cuív, Páraic, Zhang, Ping, Haque, Ashraful, Hill, Geoffrey R., Sly, Peter D., Upham, John W. and Phipps, Simon (2017). Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. The Journal of Experimental Medicine, 215 (2), 537-557. doi: 10.1084/jem.20170298 |
2017 Journal Article Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16Xi, Yang, Troy, Niamh M., Anderson, Denise, Pena, Olga M., Lynch, Jason P., Phipps, Simon, Bosco, Anthony and Upham, John W. (2017). Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16. Frontiers in Immunology, 8 (OCT) 1351, 1351. doi: 10.3389/fimmu.2017.01351 |
2017 Journal Article Presence of atopy increases the risk of asthma relapseTeoh, Laurel, Mackay, Ian M, Van Asperen, Peter P, Acworth, Jason P, Hurwitz, Mark, Upham, John W, Siew, Weng Hou, Wang, Claire Y T, Sloots, Theo P, Neeman, Teresa and Chang, Anne B (2017). Presence of atopy increases the risk of asthma relapse. Archives of disease in childhood, 103 (4), 346-351. doi: 10.1136/archdischild-2017-312982 |
2017 Journal Article Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trialGupta, D., Winckel, K., Burrows, J., Ross, J. and Upham, J. W. (2017). Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trial. Journal of Smoking Cessation, 12 (1), 1-10. doi: 10.1017/jsc.2015.14 |
2017 Journal Article Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1βChen, Alice C.-H., Xi, Yang, Carroll, Melanie, Petsky, Helen L., Gardiner, Samantha J., Pizzutto, Susan J., Yerkovich, Stephanie T., Baines, Katherine J., Gibson, Peter G., Hodge, Sandra, Masters, Ian B., Buntain, Helen M., Chang, Anne B. and Upham, John W. (2017). Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β. ERJ Open Research, 3 (4) 00025-2017, 00025-2017. doi: 10.1183/23120541.00025-2017 |
2017 Journal Article Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trialGibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather, Taylor, Steven L., Leong, Lex E. X., Rogers, Geraint B. and Simpson, Jodie L. (2017). Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. The Lancet, 390 (10095), 659-668. doi: 10.1016/S0140-6736(17)31281-3 |
2017 Journal Article Management of hypoxaemic respiratory failure in a Respiratory High-dependency UnitHukins, Craig, Wong, Mimi, Murphy, Michelle and Upham, John (2017). Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit. Internal Medicine Journal, 47 (7), 784-792. doi: 10.1111/imj.13403 |
2017 Journal Article Bronchiectasis in children: current concepts in immunology and microbiologyPizzutto, Susan J., Hare, Kim M. and Upham, John W. (2017). Bronchiectasis in children: current concepts in immunology and microbiology. Frontiers in Pediatrics, 5 123, 123. doi: 10.3389/fped.2017.00123 |
2017 Journal Article Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiologyTaylor, Steven L., Leong, Lex E. X., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B., Gibson, Peter G., Simpson, Jodie L. and Rogers, Geraint B. (2017). Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology. Journal of Allergy and Clinical Immunology, 141 (1), 94-103.e15. doi: 10.1016/j.jaci.2017.03.044 |
2017 Journal Article Can biomarkers help us hit targets in difficult-to-treat asthma?Fricker, Michael, Heaney, Liam G. and Upham, John W. (2017). Can biomarkers help us hit targets in difficult-to-treat asthma?. Respirology, 22 (3), 430-442. doi: 10.1111/resp.13014 |
2017 Journal Article ResponseWurzel, Danielle F., Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W. and Chang, Anne B. (2017). Response. Chest, 151 (4), 940-941. doi: 10.1016/j.chest.2016.12.030 |
2017 Journal Article Dendritic cells in human lung disease: recent advancesUpham, John W. and Xi, Yang (2017). Dendritic cells in human lung disease: recent advances. Chest, 151 (3), 668-673. doi: 10.1016/j.chest.2016.09.030 |
2017 Journal Article RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthmaArikkatt, Jaisy, Ullah, Md Ashik, Short, Kirsty Renfree, Zhang, Vivian, Gan, Wan Jun, Loh, Zhixuan, Werder, Rhiannon B., Simpson, Jennifer, Sly, Peter D., Mazzone, Stuart B., Spann, Kirsten M., Ferreira, Manuel A R., Upham, John W., Sukkar, Maria B. and Phipps, Simon (2017). RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma. eLife, 6 e21199. doi: 10.7554/eLife.21199 |