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2025 Journal Article Biomarker profile and disease burden associated with intermittent and long-term oral corticosteroid use in patients with severe asthma prior to biologic initiation in real-life (STAR)Schleich, Florence, Larenas-Linnemann, Désirée, Altraja, Alan, Pérez de Llano, Luis, Kostikas, Konstantinos, Sadatsafavi, Mohsen, Bourdin, Arnaud, Alton Pleasants, Roy, Hew, Mark, Chen, Wenjia, Jiménez-Maldonado, Libardo, Couillard, Simon, Suppli Ulrik, Charlotte, Bulkhi, Adeeb A., Tsai, Ming-Ju, Christoff, George C., Papadopoulos, Nikolaos G., Pfeffer, Paul E., Ryan, Dermot, Bergeron, Celine, Al-Ahmad, Mona S., Dorscheid, Delbert R., Wang, Eileen, Blakey, John D., Cochrane, Belinda, Peters, Matthew J., Popov, Todor A., Torres-Duque, Carlos A., Hansen, Susanne ... Price, David B. (2025). Biomarker profile and disease burden associated with intermittent and long-term oral corticosteroid use in patients with severe asthma prior to biologic initiation in real-life (STAR). World Allergy Organization Journal, 18 (7) 101066, 101066. doi: 10.1016/j.waojou.2025.101066 |
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2025 Journal Article Impact of clinical remission on quality of life in severe eosinophilic asthma treated with mepolizumabHamada, Yuto, Thomas, Dennis, McDonald, Vanessa M., Harvey, Erin S., Fricker, Michael, Gillman, Andrew, Hew, Mark, Kritikos, Vicky, Upham, John W. and Gibson, Peter G. (2025). Impact of clinical remission on quality of life in severe eosinophilic asthma treated with mepolizumab. Annals of Allergy, Asthma & Immunology. doi: 10.1016/j.anai.2025.06.017 |
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2025 Journal Article Early Treatment Response to Mepolizumab Predicts Clinical Remission in Severe Eosinophilic AsthmaHamada, Yuto, Gibson, Peter G., Harvey, Erin S., Stevens, Sean, Lewthwaite, Hayley, Fricker, Michael, McDonald, Vanessa M., Gillman, Andrew, Hew, Mark, Kritikos, Vicky, Upham, John W. and Thomas, Dennis (2025). Early Treatment Response to Mepolizumab Predicts Clinical Remission in Severe Eosinophilic Asthma. Journal of Allergy and Clinical Immunology: In Practice, 13 (2), 333-342.e9. doi: 10.1016/j.jaip.2024.10.041 |
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2025 Journal Article Experiences of Oral Corticosteroid Use and Adverse Effects: A National Cross-Sectional Survey of People with AsthmaJones, Arwel W., Mcdonald, Vanessa M., Mcloughlin, Rebecca F., Vella, Teresa M., Flynn, Anthony W., Blakey, John, Wolfenden, Luke, Hew, Mark, Upham, John W., Thomas, Dennis, Bardin, Philip and Holland, Anne E. (2025). Experiences of Oral Corticosteroid Use and Adverse Effects: A National Cross-Sectional Survey of People with Asthma. Patient Preference and Adherence, 19, 75-85. doi: 10.2147/PPA.S487743 |
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2025 Journal Article Predicting future exacerbations in uncontrolled asthma: A discovery/validation approach using large-scale clinical proteomicsJurak, Lisa M., Yang, Ian A., Simpson, Jodie L., Gibson, Peter G., Hill, Michelle M. and Upham, John W. (2025). Predicting future exacerbations in uncontrolled asthma: A discovery/validation approach using large-scale clinical proteomics. Journal of Allergy and Clinical Immunology, 155 (6), 1846-1856.e2. doi: 10.1016/j.jaci.2025.02.028 |
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2025 Journal Article Distinct trajectories of treatment response to mepolizumab toward remission in patients with severe eosinophilic asthmaHamada, Yuto, Thomas, Dennis, Harvey, Erin S., Stevens, Sean, Fricker, Michael, Lewthwaite, Hayley, McDonald, Vanessa M., Gillman, Andrew, Hew, Mark, Kritikos, Vicky, Upham, John W. and Gibson, Peter G. (2025). Distinct trajectories of treatment response to mepolizumab toward remission in patients with severe eosinophilic asthma. The European respiratory journal, 65 (1) 2400782, 2400782. doi: 10.1183/13993003.00782-2024 |
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2025 Journal Article Unlocking Asthma Remission: Key Insights From an Expert Roundtable DiscussionThomas, Dennis, Lewthwaite, Hayley, Gibson, Peter G., Majellano, Eleanor, Clark, Vanessa, Fricker, Michael, Hamada, Yuto, Anderson, Gary P., Backer, Vibeke, Bardin, Philip, Beasley, Richard, Chien, Jimmy, Farah, Claude S., Harrington, John, Harvey, Erin, Hew, Mark, Holland, Anne E., Jenkins, Christine, Katelaris, Constance H., Katsoulotos, Gregory, Murray, Kirsty, Peters, Matthew, Thomas, Rejoy, Tonga, Katrina, Upham, John W., Wark, Peter and McDonald, Vanessa M. (2025). Unlocking Asthma Remission: Key Insights From an Expert Roundtable Discussion. Respirology, 30 (6), 466-479. doi: 10.1111/resp.70047 |
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2024 Journal Article Patient-centred composite scores as tools for assesment of response to biological therapy for paediatric and adult severe asthmaKhaleva, Ekaterina, Brightling, Chris, Eiwegger, Thomas, Altraja, Alan, Bégin, Philippe, Blumchen, Katharina, Bossios, Apostolos, Bourdin, Arnaud, Ten Brinke, Anneke, Brusselle, Guy, Silvia Bumbacea, Roxana, Bush, Andrew, Casale, Thomas B, Clarke, Graham W., Chaudhuri, Rekha, Fan Chung, Kian, Coleman, Courtney, Corren, Jonathan, Dahlén, Sven-Erik, Deschildre, Antoine, Djukanovic, Ratko, Eger, Katrien, Exley, Andrew, Fleming, Louise, Fowler, Stephen J., Gaillard, Erol A., Gappa, Monika, Gupta, Atul, Michael Haitchi, Hans ... on behalf of the 3TR Asthma Definition of Response Working Group (2024). Patient-centred composite scores as tools for assesment of response to biological therapy for paediatric and adult severe asthma. European Respiratory Journal, 65 (3) 2400691, 1-18. doi: 10.1183/13993003.00691-2024 |
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2024 Journal Article Exploring definitions and predictors of severe asthma clinical remission after biologic treatment in adultsPerez-De-Llano, Luis, Scelo, Ghislaine, Tran, Trung N., Le, Tham T., Fagerås, Malin, Cosio, Borja G., Peters, Matthew, Pfeffer, Paul E., Al-Ahmad, Mona, Al-Lehebi, Riyad O., Altraja, Alan, Bergeron, Celine, Bjermer, Leif H., Bjerrum, Anne S., Bulathsinhala, Lakmini, Busby, John, Cano Rosales, Diana J., Canonica, Giorgio W., Carter, Victoria A., Charriot, Jeremy, Christoff, George C., Denton, Eve J., Dorscheid, Delbert R., Fernandez Sanchez, Maria J., Fonseca, João A., Gibson, Peter G., Goh, Celine Y.Y., Heaney, Liam G., Heffler, Enrico ... Price, David B. (2024). Exploring definitions and predictors of severe asthma clinical remission after biologic treatment in adults. American Journal of Respiratory and Critical Care Medicine, 210 (7), 869-880. doi: 10.1164/rccm.202311-2192OC |
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2024 Journal Article Exploring definitions and predictors of response to biologics for severe asthmaScelo, Ghislaine, Tran, Trung N., Le, Tham T., Fagerås, Malin, Dorscheid, Delbert, Busby, John, Al-Ahmad, Mona, Al-Lehebi, Riyad, Altraja, Alan, Beastall, Aaron, Bergeron, Celine, Bjermer, Leif, Bjerrum, Anne S., Cano-Rosales, Diana Jimena, Canonica, Giorgio Walter, Carter, Victoria, Charriot, Jeremy, Christoff, George C., Cosio, Borja G., Denton, Eve, Fernandez-Sanchez, Maria Jose, Fonseca, João A., Gibson, Peter G., Goh, Celine, Heaney, Liam G., Heffler, Enrico, Hew, Mark, Iwanaga, Takashi, Katial, Rohit ... Price, David B. (2024). Exploring definitions and predictors of response to biologics for severe asthma. Journal of Allergy and Clinical Immunology: In Practice, 12 (9), 2347-2361. doi: 10.1016/j.jaip.2024.05.016 |
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2024 Journal Article Real-world biologics response and super-response in the International Severe Asthma Registry cohortDenton, Eve, Hew, Mark, Peters, Matthew J., Upham, John W., Bulathsinhala, Lakmini, Tran, Trung N., Martin, Neil, Bergeron, Celine, Al-Ahmad, Mona, Altraja, Alan, Larenas-Linnemann, Desiree, Murray, Ruth, Celis-Preciado, Carlos Andres, Al-Lehebi, Riyad, Belhassen, Manon, Bhutani, Mohit, Bosnic-Anticevich, Sinthia Z., Bourdin, Arnaud, Brusselle, Guy G., Busby, John, Canonica, Giorgio Walter, Heffler, Enrico, Chapman, Kenneth R., Charriot, Jeremy, Christoff, George C., Chung, Li Ping, Cosio, Borja G., Cote, Andreanne, Costello, Richard W. ... Price, David B. (2024). Real-world biologics response and super-response in the International Severe Asthma Registry cohort. Allergy, 79 (10), 2700-2716. doi: 10.1111/all.16178 |
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2024 Journal Article Twenty-four month outcomes of extended- versus standard-course antibiotic therapy in children hospitalized with pneumonia in high-risk settings: a randomized controlled trialKok, Hing C., McCallum, Gabrielle B., Yerkovich, Stephanie T., Grimwood, Keith, Fong, Siew M., Nathan, Anna M., Byrnes, Catherine A., Ware, Robert S., Nachiappan, Nachal, Saari, Noorazlina, Morris, Peter S., Yeo, Tsin W., Oguoma, Victor M., Masters, I. Brent, de Bruyne, Jessie A., Eg, Kah P., Lee, Bilawara, Ooi, Mong H., Upham, John W., Torzillo, Paul J. and Chang, Anne B. (2024). Twenty-four month outcomes of extended- versus standard-course antibiotic therapy in children hospitalized with pneumonia in high-risk settings: a randomized controlled trial. Pediatric Infectious Disease Journal, 43 (9), 872-879. doi: 10.1097/inf.0000000000004407 |
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2024 Journal Article Biologics (mepolizumab and omalizumab) induced remission in severe asthma patientsThomas, Dennis, McDonald, Vanessa M., Stevens, Sean, Harvey, Erin S., Baraket, Melissa, Bardin, Philip, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Gillman, Andrew, Hew, Mark, Hodge, Sandra, James, Alan, Jenkins, Christine, Katelaris, Constance H., Katsoulotos, Gregory P., Langton, David, Lee, Joy, Marks, Guy, Peters, Matthew, Radhakrishna, Naghmeh, Reynolds, Paul N., Rimmer, Janet, Sivakumaran, Pathmanathan, Upham, John W., Wark, Peter, Yang, Ian A. and Gibson, Peter G. (2024). Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients. Allergy, 79 (2), 384-392. doi: 10.1111/all.15867 |
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2024 Journal Article Azithromycin induced asthma remission in adults with persistent uncontrolled asthma: a secondary analysis of a randomised, double-blind, placebo-controlled trialThomas, Dennis, McDonald, Vanessa M., Stevens, Sean, Baraket, Melissa, Hodge, Sandra, James, Alan, Jenkins, Christine, Marks, Guy B., Peters, Matthew, Reynolds, Paul, Upham, John W., Yang, Ian A. and Gibson, Peter G. (2024). Azithromycin induced asthma remission in adults with persistent uncontrolled asthma: a secondary analysis of a randomised, double-blind, placebo-controlled trial. CHEST, 166 (2), 262-270. doi: 10.1016/j.chest.2024.02.048 |
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2024 Journal Article Effects of moderate- versus vigorous-intensity exercise training on asthma outcomes in adultsValkenborghs, Sarah R., Wood, Lisa G., Callister, Robin, Upham, John W., Grainge, Christopher L., Anderson, Sophie, Williams, Lily M., McLoughlin, Rebecca F., Williams, Evan J. and Scott, Hayley A. (2024). Effects of moderate- versus vigorous-intensity exercise training on asthma outcomes in adults. Journal of Allergy and Clinical Immunology: In Practice, 12 (10), 2744-2753. doi: 10.1016/j.jaip.2024.06.015 |
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2023 Journal Article Impact of landscape fire smoke exposure on patients with asthma with or without laryngeal hypersensitivityVertigan, Anne E., Harvey, Erin S., Beyene, Tesfalidet, Van Buskirk, Joseph, Holliday, Elizabeth G., Bone, Sarah L., McDonald, Vanessa M., Horvat, Jay C., Murphy, Vanessa E., Jensen, Megan E., Morgan, Geoffrey G., Zosky, Graeme R., Peters, Matthew, Farah, Claude S., Jenkins, Christine R., Katelaris, Constance H., Harrington, John, Langton, David, Bardin, Philip, Katsoulotos, Gregory P., Upham, John W., Chien, Jimmy, Bowden, Jeffrey J., Rimmer, Janet, Bell, Rose and Gibson, Peter G. (2023). Impact of landscape fire smoke exposure on patients with asthma with or without laryngeal hypersensitivity. The Journal of Allergy and Clinical Immunology: In Practice, 11 (10), 3107-3115.e2. doi: 10.1016/j.jaip.2023.06.015 |
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2023 Journal Article Severe asthma ILC2s demonstrate enhanced proliferation that is modified by biologicsMalik, Bilal, Bartlett, Nathan W., Upham, John W., Nichol, Kristy S., Harrington, John and Wark, Peter A. B. (2023). Severe asthma ILC2s demonstrate enhanced proliferation that is modified by biologics. Respirology, 28 (8), 758-766. doi: 10.1111/resp.14506 |
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2023 Journal Article Right ventricular functional recovery assessment with stress echocardiography and cardiopulmonary exercise testing after pulmonary embolism: a pilot prospective multicentre studySamaranayake, Chinthaka Bhagya, Upham, John, Tran, Khoa, Howard, Luke S, Nguyen, Sean, Lwin, Myo, Anderson, James, Wahi, Sudhir, Price, Laura C, Wort, Stephen, Li, Wei, McCabe, Colm and Keir, Gregory J (2023). Right ventricular functional recovery assessment with stress echocardiography and cardiopulmonary exercise testing after pulmonary embolism: a pilot prospective multicentre study. BMJ Open Respiratory Research, 10 (1) e001637, e001637. doi: 10.1136/bmjresp-2023-001637 |
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2023 Journal Article Can Allergen Immunotherapy Improve Antiviral Immunity in Patients with Allergic Asthma?Upham, John W. (2023). Can Allergen Immunotherapy Improve Antiviral Immunity in Patients with Allergic Asthma?. American Journal of Respiratory and Critical Care Medicine, 207 (9), 1112-1114. doi: 10.1164/rccm.202302-0234ed |
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2023 Journal Article Comorbidities modify the phenotype but not the treatment effectiveness to mepolizumab in severe eosinophilic asthmaKritikos, Vicky, Harvey, Erin S., Stevens, Sean, Katelaris, Constance H., Langton, David, Rimmer, Janet, Farah, Claude S., Gillman, Andrew, Hew, Mark, Radhakrishna, Naghmeh, Thomas, Dennis, Gibson, Peter G., Baraket, Melissa, Bardin, Philip, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Grainge, Christopher, Harkness, Nicholas, Harrington, Zinta, Jenkins, Christine, Katsoulotos, Gregory P., McDonald, Vanessa M., Lee, Joy, Peters, Matthew, Reddel, Helen K., Reynolds, Paul N., Sivakumaran, Pathmanathan ... Wark, Peter A. B. (2023). Comorbidities modify the phenotype but not the treatment effectiveness to mepolizumab in severe eosinophilic asthma. Journal of Allergy and Clinical Immunology: In Practice, 11 (3), 885-895.e13. doi: 10.1016/j.jaip.2022.12.004 |
