2021 Journal Article Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatmentNiessen, Natalie M., Gibson, Peter G., Baines, Katherine J., Barker, Daniel, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Simpson, Jodie L. and Fricker, Michael (2021). Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment. Allergy, 76 (7) all.14768, 2090-2101. doi: 10.1111/all.14768 |
2021 Journal Article Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trialRuffles, Tom J. C., Goyal, Vikas, Marchant, Julie M., Masters, I. Brent, Yerkovich, Stephanie, Buntain, Helen, Cook, Anne, Schultz, Andre, Upham, John W., Champion, Anita, Versteegh, Lesley and Chang, Anne B. (2021). Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial. The Lancet Respiratory Medicine, 9 (10), 1121-1129. doi: 10.1016/s2213-2600(21)00104-1 |
2021 Journal Article Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort studyRuffles, Tom J.C., Marchant, Julie M., Masters, Ian B., Yerkovich, Stephanie T., Wurzel, Danielle F., Gibson, Peter G., Busch, Greta, Baines, Katherine J., Simpson, Jodie L., Smith-Vaughan, Heidi C., Pizzutto, Susan J., Buntain, Helen M., Hodge, Gregory, Hodge, Sandra, Upham, John W. and Chang, Anne B. (2021). Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort study. Respirology, 26 (3), 241-248. doi: 10.1111/resp.13950 |
2021 Journal Article Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetingsMaltby, Steven, McDonald, Vanessa M., Upham, John W., Bowler, Simon D., Chung, Li Ping, Denton, Eve J., Fingleton, James, Garrett, Jeffrey, Grainge, Christopher L., Hew, Mark, James, Alan L., Jenkins, Christine, Katsoulotos, Gregory, King, Gregory G., Langton, David, Marks, Guy B., Menzies‐Gow, Andrew, Niven, Robert M., Peters, Matthew, Reddel, Helen K., Thien, Francis, Thomas, Paul S., Wark, Peter A. B., Yap, Elaine, Gibson, Peter G. and , (2021). Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings. Internal Medicine Journal, 51 (2) imj.14806, 169-180. doi: 10.1111/imj.14806 |
2021 Journal Article The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthmaO Neill, Ciaran, Gibson, Peter G., Heaney, Liam G., Upham, John W., Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, Jenkins, Christine R., Peters, Matthew, Marks, Guy B., James, Alan L. and Simpson, Jodie L. (2021). The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma. European Respiratory Journal, 57 (2) 2002436, 2002436. doi: 10.1183/13993003.02436-2020 |
2021 Journal Article Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control studySamaranayake, Chinthaka B., Keir, Gregory, McCabe, Colm, Anderson, James, Tran, Khoa and Upham, John W. (2021). Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study. ERJ Open Research, 7 (1) 00762, 1-4. doi: 10.1183/23120541.00762-2020 |
2020 Journal Article Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signalingvan der Heide, Saskia L., Xi, Yang and Upham, John W. (2020). Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signaling. Frontiers in Cellular and Infection Microbiology, 10 510619, 1-12. doi: 10.3389/fcimb.2020.510619 |
2020 Journal Article Cumulative dispensing of high oral corticosteroid doses for treating asthma in AustraliaHew, Mark, McDonald, Vanessa M, Bardin, Phil G, Chung, Li Ping, Farah, Claude S, Barnard, Amanda, Cooper, Mark S, Gibson, Peter G and Upham, John W (2020). Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia. Medical Journal of Australia, 213 (7), 316-320. doi: 10.5694/mja2.50758 |
2020 Journal Article Plasmacytoid dendritic cells and asthma: a review of current knowledgeXi, Yang and Upham, John W. (2020). Plasmacytoid dendritic cells and asthma: a review of current knowledge. Expert Review of Respiratory Medicine, 14 (11), 1095-`1106. doi: 10.1080/17476348.2020.1803741 |
2020 Journal Article HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodellingLoh, Zhixuan, Simpson, Jennifer, Ullah, Ashik, Zhang, Vivian, Gan, Wan J., Lynch, Jason P., Werder, Rhiannon B., Sikder, Al Amin, Lane, Katie, Sim, Choon Boon, Porrello, Enzo, Mazzone, Stuart B., Sly, Peter D., Steptoe, Raymond J., Spann, Kirsten M., Sukkar, Maria B., Upham, John W. and Phipps, Simon (2020). HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling. PLoS Pathogens, 16 (7) e1008651, 1-21. doi: 10.1371/journal.ppat.1008651 |
2020 Journal Article How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?Upham, John W. and Jurak, Lisa M. (2020). How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?. Clinical and Experimental Allergy, 50 (9) cea.13694, 994-1006. doi: 10.1111/cea.13694 |
2020 Journal Article Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsetsMurray, Liisa M., Yerkovich, Stephanie T., Ferreira, Manuel A. and Upham, John W. (2020). Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsets. European Respiratory Journal, 56 (4) 1902453, 1902453. doi: 10.1183/13993003.02453-2019 |
2020 Journal Article Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in childrenHodge, Sandra, Macowan, Matthew, Liu, Hong, Hamon, Rhys, Chen, Alice C.-H., Marchant, Julie M., Pizzutto, Susan J., Upham, John W. and Chang, Anne B. (2020). Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in children. Pediatric Pulmonology, 55 (6), 1414-1423. doi: 10.1002/ppul.24728 |
2020 Journal Article Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cellsSimpson, Jennifer, Loh, Zhixuan, Ullah, Md Ashik, Lynch, Jason P., Werder, Rhiannon B., Collinson, Natasha, Zhang, Vivian, Dondelinger, Yves, Bertrand, Mathieu J M, Everard, Mark L., Blyth, Christopher C., Hartel, Gunter, Van Oosterhout, Antoon J., Gough, Peter J., Bertin, John, Upham, John W., Spann, Kirsten M. and Phipps, Simon (2020). Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells. American Journal of Respiratory and Critical Care Medicine, 201 (11), 1358-1371. doi: 10.1164/rccm.201906-1149OC |
2020 Journal Article Mepolizumab effectiveness and identification of super-responders in severe asthmaHarvey, Erin S., Langton, David, Katelaris, Constance, Stevens, Sean, Farah, Claude S., Gillman, Andrew, Harrington, John, Hew, Mark, Kritikos, Vicky, Radhakrishna, Naghmeh, Bardin, Philip, Peters, Matthew, Reynolds, Paul N., Upham, John W., Baraket, Melissa, Bowler, Simon, Bowden, Jeffrey, Chien, Jimmy, Chung, Li Ping, Grainge, Christopher, Jenkins, Christine, Katsoulotos, Gregory P., Lee, Joy, McDonald, Vanessa M., Reddel, Helen K., Rimmer, Janet, Wark, Peter A B and Gibson, Peter G. (2020). Mepolizumab effectiveness and identification of super-responders in severe asthma. The European Respiratory Journal, 55 (5) 1902420, 1902420. doi: 10.1183/13993003.02420-2019 |
2020 Journal Article Asthma in children and adults – what are the differences and what can they tell us about asthma?Turner, Steve and Upham, John W. (2020). Asthma in children and adults – what are the differences and what can they tell us about asthma?. Frontiers in Pediatrics, 8 141, 141. doi: 10.3389/fped.2020.00141 |
2020 Journal Article Severe Asthma Toolkit: An online resource for multidisciplinary health professionals - Needs assessment, development process and user analytics with survey feedbackMaltby, Steven, Gibson, Peter G., Reddel, Helen K., Smith, Lorraine, Wark, Peter A. B., King, Gregory G., Upham, John W., Clark, Vanessa L., Hew, Mark, Owens, Louisa, Oo, Stephen, James, Alan L., Thompson, Bruce, Marks, Guy B. and McDonald, Vanessa M. (2020). Severe Asthma Toolkit: An online resource for multidisciplinary health professionals - Needs assessment, development process and user analytics with survey feedback. BMJ Open, 10 (3) e032877, 1-10. doi: 10.1136/bmjopen-2019-032877 |
2020 Journal Article Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthmaLynch, Jason P., Werder, Rhiannon B., Curren, Bodie F., Sikder, Md. Al Amin, Ullah, Ashik, Sebina, Ismail, Rashid, Ridwan B., Zhang, Vivian, Upham, John W., Hill, Geoff R., Steptoe, Raymond J. and Phipps, Simon (2020). Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma. Mucosal Immunology, 13 (4), 652-664. doi: 10.1038/s41385-020-0268-8 |
2020 Journal Article Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients : Regional IgE specificity for grass pollensKailaivasan, Thina H, Timbrell, Victoria L, Solley, Graham, Smith, William B, McLean-Tooke, Andrew, van Nunen, Sheryl, Smith, Peter, Upham, John W, Langguth, Daman and Davies, Janet M (2020). Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients : Regional IgE specificity for grass pollens. Clinical and Translational Immunology, 9 (2) e01103, e01103. doi: 10.1002/cti2.1103 |
2020 Journal Article The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018Blyth, Christopher C., Cheng, Allen C., Crawford, Nigel W., Clark, Julia E., Buttery, Jim P., Marshall, Helen S., Francis, Joshua R., McRae, Jocelynne, Kotsimbos, Tom, Kelly, Paul M., Macartney, Kristine K., on behalf of the Paediatric Active Enhanced Disease Surveillance (PAEDS), Influenza Complications Alert Network (FluCAN) Collaboration and Upham, John (2020). The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018. Vaccine, 38 (13), 2779-2787. doi: 10.1016/j.vaccine.2020.02.031 |