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2021

Journal Article

Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment

Niessen, Natalie M., Gibson, Peter G., Baines, Katherine J., Barker, Daniel, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Simpson, Jodie L. and Fricker, Michael (2021). Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment. Allergy, 76 (7) all.14768, 2090-2101. doi: 10.1111/all.14768

Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment

2021

Journal Article

Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial

Ruffles, Tom J. C., Goyal, Vikas, Marchant, Julie M., Masters, I. Brent, Yerkovich, Stephanie, Buntain, Helen, Cook, Anne, Schultz, Andre, Upham, John W., Champion, Anita, Versteegh, Lesley and Chang, Anne B. (2021). Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial. The Lancet Respiratory Medicine, 9 (10), 1121-1129. doi: 10.1016/s2213-2600(21)00104-1

Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial

2021

Journal Article

Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort study

Ruffles, Tom J.C., Marchant, Julie M., Masters, Ian B., Yerkovich, Stephanie T., Wurzel, Danielle F., Gibson, Peter G., Busch, Greta, Baines, Katherine J., Simpson, Jodie L., Smith-Vaughan, Heidi C., Pizzutto, Susan J., Buntain, Helen M., Hodge, Gregory, Hodge, Sandra, Upham, John W. and Chang, Anne B. (2021). Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort study. Respirology, 26 (3), 241-248. doi: 10.1111/resp.13950

Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort study

2021

Journal Article

Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings

Maltby, Steven, McDonald, Vanessa M., Upham, John W., Bowler, Simon D., Chung, Li Ping, Denton, Eve J., Fingleton, James, Garrett, Jeffrey, Grainge, Christopher L., Hew, Mark, James, Alan L., Jenkins, Christine, Katsoulotos, Gregory, King, Gregory G., Langton, David, Marks, Guy B., Menzies‐Gow, Andrew, Niven, Robert M., Peters, Matthew, Reddel, Helen K., Thien, Francis, Thomas, Paul S., Wark, Peter A. B., Yap, Elaine, Gibson, Peter G. and , (2021). Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings. Internal Medicine Journal, 51 (2) imj.14806, 169-180. doi: 10.1111/imj.14806

Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings

2021

Journal Article

The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma

O Neill, Ciaran, Gibson, Peter G., Heaney, Liam G., Upham, John W., Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, Jenkins, Christine R., Peters, Matthew, Marks, Guy B., James, Alan L. and Simpson, Jodie L. (2021). The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma. European Respiratory Journal, 57 (2) 2002436, 2002436. doi: 10.1183/13993003.02436-2020

The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma

2021

Journal Article

Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study

Samaranayake, Chinthaka B., Keir, Gregory, McCabe, Colm, Anderson, James, Tran, Khoa and Upham, John W. (2021). Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study. ERJ Open Research, 7 (1) 00762, 1-4. doi: 10.1183/23120541.00762-2020

Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study

2020

Journal Article

Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signaling

van der Heide, Saskia L., Xi, Yang and Upham, John W. (2020). Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signaling. Frontiers in Cellular and Infection Microbiology, 10 510619, 1-12. doi: 10.3389/fcimb.2020.510619

Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signaling

2020

Journal Article

Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia

Hew, Mark, McDonald, Vanessa M, Bardin, Phil G, Chung, Li Ping, Farah, Claude S, Barnard, Amanda, Cooper, Mark S, Gibson, Peter G and Upham, John W (2020). Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia. Medical Journal of Australia, 213 (7), 316-320. doi: 10.5694/mja2.50758

Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia

2020

Journal Article

Plasmacytoid dendritic cells and asthma: a review of current knowledge

Xi, Yang and Upham, John W. (2020). Plasmacytoid dendritic cells and asthma: a review of current knowledge. Expert Review of Respiratory Medicine, 14 (11), 1095-`1106. doi: 10.1080/17476348.2020.1803741

Plasmacytoid dendritic cells and asthma: a review of current knowledge

2020

Journal Article

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

Loh, Zhixuan, Simpson, Jennifer, Ullah, Ashik, Zhang, Vivian, Gan, Wan J., Lynch, Jason P., Werder, Rhiannon B., Sikder, Al Amin, Lane, Katie, Sim, Choon Boon, Porrello, Enzo, Mazzone, Stuart B., Sly, Peter D., Steptoe, Raymond J., Spann, Kirsten M., Sukkar, Maria B., Upham, John W. and Phipps, Simon (2020). HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling. PLoS Pathogens, 16 (7) e1008651, 1-21. doi: 10.1371/journal.ppat.1008651

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

2020

Journal Article

How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?

Upham, John W. and Jurak, Lisa M. (2020). How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?. Clinical and Experimental Allergy, 50 (9) cea.13694, 994-1006. doi: 10.1111/cea.13694

How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?

2020

Journal Article

Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsets

Murray, Liisa M., Yerkovich, Stephanie T., Ferreira, Manuel A. and Upham, John W. (2020). Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsets. European Respiratory Journal, 56 (4) 1902453, 1902453. doi: 10.1183/13993003.02453-2019

Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsets

2020

Journal Article

Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in children

Hodge, Sandra, Macowan, Matthew, Liu, Hong, Hamon, Rhys, Chen, Alice C.-H., Marchant, Julie M., Pizzutto, Susan J., Upham, John W. and Chang, Anne B. (2020). Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in children. Pediatric Pulmonology, 55 (6), 1414-1423. doi: 10.1002/ppul.24728

Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in children

2020

Journal Article

Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells

Simpson, Jennifer, Loh, Zhixuan, Ullah, Md Ashik, Lynch, Jason P., Werder, Rhiannon B., Collinson, Natasha, Zhang, Vivian, Dondelinger, Yves, Bertrand, Mathieu J M, Everard, Mark L., Blyth, Christopher C., Hartel, Gunter, Van Oosterhout, Antoon J., Gough, Peter J., Bertin, John, Upham, John W., Spann, Kirsten M. and Phipps, Simon (2020). Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells. American Journal of Respiratory and Critical Care Medicine, 201 (11), 1358-1371. doi: 10.1164/rccm.201906-1149OC

Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells

2020

Journal Article

Mepolizumab effectiveness and identification of super-responders in severe asthma

Harvey, Erin S., Langton, David, Katelaris, Constance, Stevens, Sean, Farah, Claude S., Gillman, Andrew, Harrington, John, Hew, Mark, Kritikos, Vicky, Radhakrishna, Naghmeh, Bardin, Philip, Peters, Matthew, Reynolds, Paul N., Upham, John W., Baraket, Melissa, Bowler, Simon, Bowden, Jeffrey, Chien, Jimmy, Chung, Li Ping, Grainge, Christopher, Jenkins, Christine, Katsoulotos, Gregory P., Lee, Joy, McDonald, Vanessa M., Reddel, Helen K., Rimmer, Janet, Wark, Peter A B and Gibson, Peter G. (2020). Mepolizumab effectiveness and identification of super-responders in severe asthma. The European Respiratory Journal, 55 (5) 1902420, 1902420. doi: 10.1183/13993003.02420-2019

Mepolizumab effectiveness and identification of super-responders in severe asthma

2020

Journal Article

Asthma in children and adults – what are the differences and what can they tell us about asthma?

Turner, Steve and Upham, John W. (2020). Asthma in children and adults – what are the differences and what can they tell us about asthma?. Frontiers in Pediatrics, 8 141, 141. doi: 10.3389/fped.2020.00141

Asthma in children and adults – what are the differences and what can they tell us about asthma?

2020

Journal Article

Severe Asthma Toolkit: An online resource for multidisciplinary health professionals - Needs assessment, development process and user analytics with survey feedback

Maltby, Steven, Gibson, Peter G., Reddel, Helen K., Smith, Lorraine, Wark, Peter A. B., King, Gregory G., Upham, John W., Clark, Vanessa L., Hew, Mark, Owens, Louisa, Oo, Stephen, James, Alan L., Thompson, Bruce, Marks, Guy B. and McDonald, Vanessa M. (2020). Severe Asthma Toolkit: An online resource for multidisciplinary health professionals - Needs assessment, development process and user analytics with survey feedback. BMJ Open, 10 (3) e032877, 1-10. doi: 10.1136/bmjopen-2019-032877

Severe Asthma Toolkit: An online resource for multidisciplinary health professionals - Needs assessment, development process and user analytics with survey feedback

2020

Journal Article

Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma

Lynch, Jason P., Werder, Rhiannon B., Curren, Bodie F., Sikder, Md. Al Amin, Ullah, Ashik, Sebina, Ismail, Rashid, Ridwan B., Zhang, Vivian, Upham, John W., Hill, Geoff R., Steptoe, Raymond J. and Phipps, Simon (2020). Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma. Mucosal Immunology, 13 (4), 652-664. doi: 10.1038/s41385-020-0268-8

Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma

2020

Journal Article

Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients : Regional IgE specificity for grass pollens

Kailaivasan, Thina H, Timbrell, Victoria L, Solley, Graham, Smith, William B, McLean-Tooke, Andrew, van Nunen, Sheryl, Smith, Peter, Upham, John W, Langguth, Daman and Davies, Janet M (2020). Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients : Regional IgE specificity for grass pollens. Clinical and Translational Immunology, 9 (2) e01103, e01103. doi: 10.1002/cti2.1103

Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients : Regional IgE specificity for grass pollens

2020

Journal Article

The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018

Blyth, Christopher C., Cheng, Allen C., Crawford, Nigel W., Clark, Julia E., Buttery, Jim P., Marshall, Helen S., Francis, Joshua R., McRae, Jocelynne, Kotsimbos, Tom, Kelly, Paul M., Macartney, Kristine K., on behalf of the Paediatric Active Enhanced Disease Surveillance (PAEDS), Influenza Complications Alert Network (FluCAN) Collaboration and Upham, John (2020). The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018. Vaccine, 38 (13), 2779-2787. doi: 10.1016/j.vaccine.2020.02.031

The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018