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2016

Journal Article

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network

Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Irving, Louis B., Korman, Tony M., Senenayake, Sanjaya, Macartney, Kristine K., Blyth, Christopher C., Brown, Simon, Waterer, Grant, Hewer, Robert, Friedman, N Deborah, Wark, Peter A., Simpson, Graham, Upham, John, Bowler, Simon D., Lessing, Albert, Kotsimbos, Tom and Kelly, Paul M. (2016). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network. Communicable Diseases Intelligence Quarterly Report, 40 (4), E521-E526.

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network

2016

Journal Article

Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis

Wurzel, Danielle F., Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W., Petsky, Helen L., Smith-Vaughan, Heidi, Masters, Brent, Buntain, Helen and Chang, Anne B. (2016). Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis. Chest, 150 (5), 1101-1108. doi: 10.1016/j.chest.2016.06.030

Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis

2016

Journal Article

Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria

Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., Guo, M., Reddel, H. K., Jenkins, C., Marks, G. B., Thien, F., Rimmer, J., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Wright, C., Bint, M., Yozghatlian, V., Burgess, S., Sivakumaran, P., Yan, K. Y., Kritikos, V., Peters, M., Baraket, M., Aminazad, A., Robinson, P., Jaffe, A. ... Gibson, P. G. (2016). Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria. Clinical and Experimental Allergy, 46 (11), 1407-1415. doi: 10.1111/cea.12774

Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria

2016

Journal Article

Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity

Lynch, Jason P., Werder, Rhiannon B., Simpson, Jennifer, Loh, Zhixuan, Zhang, Vivian, Haque, Ashraful, Spann, Kirsten, Sly, Peter D., Mazzone, Stuart B., Upham, John W. and Phipps, Simon (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity. Journal of Allergy and Clinical Immunology, 138 (5), 1326-1337. doi: 10.1016/j.jaci.2016.02.039

Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity

2016

Journal Article

Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

Navarro, Severine, Pickering, Darren A., Ferreira, Ivana B., Jones, Linda, Ryan, Stephanie, Troy, Sally, Leech, Andrew, Hotez, Peter J., Zhan, Bin, Laha, Thewarach, Prentice, Roger, Sparwasser, Tim, Croese, John, Engwerda, Christian R., Upham, John W., Julia, Valerie, Giacomin, Paul R. and Loukas, Alex (2016). Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine, 8 (362) 362ra143, 362ra143-362ra143. doi: 10.1126/scitranslmed.aaf8807

Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

2016

Journal Article

Understanding the immune and inflammatory response to rhinoviruses: recent advances with relevance to asthma

Kunarajah, Kuhan, Pena, Olga and Upham, John W. (2016). Understanding the immune and inflammatory response to rhinoviruses: recent advances with relevance to asthma. Current Respiratory Medicine Reviews, 12 (3), 215-224. doi: 10.2174/1573398X12666160909102919

Understanding the immune and inflammatory response to rhinoviruses: recent advances with relevance to asthma

2016

Journal Article

Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the influenza complications alert network (FluCAN)

Blyth, C. C., Macartney, K. K., Hewagama, S., Senenayake, S., Friedman, N. D., Simpson, G., Upham, J., Kotsimbos, T., Kelly, P. and Cheng, A. C. (2016). Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the influenza complications alert network (FluCAN). Eurosurveillance, 21 (30), 25-33. doi: 10.2807/1560-7917.ES.2016.21.30.30301

Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the influenza complications alert network (FluCAN)

2016

Journal Article

Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype

Scott, H. A., Gibson, P. G., Garg, M. L., Upham, J. W. and Wood, L. G. (2016). Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype. Allergy, 71 (7), 1037-1047. doi: 10.1111/all.12891

Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype

2016

Journal Article

Identification of STOML2 as a putative novel asthma risk gene associated with IL6R

Revez, J. A., Matheson, M. C., Hui, J., Baltic, S., James, A., Upham, J. W., Dharmage, S., Thompson, P. J., Martin, N. G., Hopper, J. L. and Ferreira, M. A. R. (2016). Identification of STOML2 as a putative novel asthma risk gene associated with IL6R. Allergy, 71 (7), 1020-1030. doi: 10.1111/all.12869

Identification of STOML2 as a putative novel asthma risk gene associated with IL6R

2016

Journal Article

Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry

Gibson, P. G., Reddel, H., McDonald, V. M., Marks, G., Jenkins, C., Gillman, A., Upham, J., Sutherland, M., Rimmer, J., Thien, F., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Robinson, P., Wright, C., Yozghatlian, V., Burgess, S., Sivakumaran, P., Jaffe, A., Bowden, J., Wark, P. A., Yan, K. Y., Kritikos, V., Peters, M., Hew, M., Aminazad, A. ... Guo, M. (2016). Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry. Internal Medicine Journal, 46 (9), 1054-1062. doi: 10.1111/imj.13166

Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry

2016

Journal Article

Periostin levels and eosinophilic inflammation in poorly-controlled asthma

Simpson, Jodie L., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Jia, Guiquan, Holweg, Cecile T. J. and Gibson, Peter G. (2016). Periostin levels and eosinophilic inflammation in poorly-controlled asthma. BMC Pulmonary Medicine, 16 (1) 67, 67.1-67.7. doi: 10.1186/s12890-016-0230-4

Periostin levels and eosinophilic inflammation in poorly-controlled asthma

2016

Journal Article

Combination long acting bronchodilators for COPD

Upham, John W. and Gleeson, Sarah J. (2016). Combination long acting bronchodilators for COPD. Medicine Today, 17 (4), 73-74.

Combination long acting bronchodilators for COPD

2016

Journal Article

Vitamin D in asthma: is the golden bullet losing its luster?

Upham, John W. and Sly, Peter D. (2016). Vitamin D in asthma: is the golden bullet losing its luster?. American Journal of Respiratory and Critical Care Medicine, 193 (6), 598-600. doi: 10.1164/rccm.201511-2213ED

Vitamin D in asthma: is the golden bullet losing its luster?

2016

Journal Article

Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma

Simpson, Jodie L., Daly, Joshua, Baines, Katherine J., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Hugenholtz, Philip, Willner, Dana and Gibson, Peter G. (2016). Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma. European Respiratory Journal, 47 (3), 792-800. doi: 10.1183/13993003.00405-2015

Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma

2016

Journal Article

Protracted bacterial bronchitis: the last decade and the road ahead

Chang, Anne B., Upham, John W., Masters, I. Brent, Redding, Gregory R., Gibson, Peter G., Marchant, Julie M. and Grimwood, Keith (2016). Protracted bacterial bronchitis: the last decade and the road ahead. Pediatric Pulmonology, 51 (3), 225-242. doi: 10.1002/ppul.23351

Protracted bacterial bronchitis: the last decade and the road ahead

2016

Journal Article

Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids

Simpson, Jodie L., Carroll, Melanie, Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Gibson, Peter G. and Upham, John W. (2016). Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids. Chest, 149 (3), 704-713. doi: 10.1016/j.chest.2015.12.018

Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids

2016

Journal Article

Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?

Hodge, Sandra, Upham, John W., Pizzutto, Susan, Petsky, Helen L., Yerkovich, Stephanie, Baines, Katherine J., Gibson, Peter, Simpson, Jodie L., Buntain, Helen, Chen, Alice C. H., Hodge, Greg and Chang, Anne B. (2016). Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?. Chest, 149 (2), 508-515. doi: 10.1016/j.chest.2015.10.066

Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?

2016

Journal Article

Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis(Review)

Pizzutto, Susan J., Upham, John W., Yerkovich, Stephanie T. and Chang, Anne B. (2016). Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis(Review). Cochrane Database of Systematic Reviews, 2016 (1) CD007525. doi: 10.1002/14651858.CD007525.pub3

Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis(Review)

2016

Journal Article

Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma

Hodge, S., Hodge, G., Simpson, J. L., Yang, I. A., Upham, J., James, A., Gibson, P. G. and Reynolds, P. N. (2016). Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma. Clinical and Experimental Allergy, 46 (1), 60-70. doi: 10.1111/cea.12634

Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma

2015

Journal Article

Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?

Xi, Yang, Finlayson, Arvid, White, Oliva J., Carroll, Melanie L. and Upham, John W. (2015). Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?. Clinical and Translational Immunology, 4 (10) e46, e46. doi: 10.1038/cti.2015.27

Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?